Covariate-adjusted construction of gene regulatory networks using a combination of generalized linear model and penalized maximum likelihood. by Omid Chatrabgoun, Alireza Daneshkhah, Parisa Torkaman, Mark Johnston, Nader Sohrabi Safa, Ali Kashif Bashir

“…Also, we exhibit flexibility of the proposed method presented in this paper by comparing with the other methods to demonstrate the super validity of our approach.…”
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Investigating the impact of integrating land consolidation with agricultural mechanization on the technical, energy, and environmental dimensions of paddy production by Farshad Haghjooy Maklavani, Mohammad Gholami Parashkoohi, Davood Mohammad Zamani, Hamed Afshari

“… This research investigates how the integration of land consolidation and agricultural mechanization can enhance the technical efficiency, energy consumption, and environmental sustainability of paddy cultivation compared to conventional farming practices. Our primary objective is to assess whether consolidated and mechanized farming systems result in higher productivity and lower energy use, while also reducing environmental impacts such as greenhouse gas emissions, water consumption, and soil erosion. …”
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Proactive Distributed Emergency Response With Heterogeneous Tasks Allocation by Justice Darko, Hyoshin Park

“…Overall, our model reports a significant reduction in total incident delay compared to conventional TIM models. With UAV support, we demonstrate a further decrease in the total incident delay ranging between 5% and 45% for the different number of incidents. …”
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A Comparison between the Effectiveness of computerized Cognitive Rehabilitation Training and transcranial Direct Current Stimulation on Dialysis Patients’ Executive Functions by Fatemeh Firouzan, Vahid Sadeghi-Firoozabadi, Vahid Nejati, Jalil Fathabadi, Ahmad Firouzan

“…The present study aims to compare the efficiency of transcranial Direct Current Stimulation (tDCS) with computerized Cognitive Rehabilitation Training (cCRT) on dialysis patients' executive functions…”
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Hydrophobic deep eutectic solvents as novel, sustainable aids for intracellular protein release from Saccharomyces cerevisiae by Tjalling Gijsbert Tjalsma, Yannick Patrice Didion, Ziran Su, Magdalena Malankowska, Pablo Torres-Montero, José Luis Martínez, Manuel Pinelo

“…Despite the similar structures of the hydrogen bond acceptor (HBA) and hydrogen bond donor (HBD), DESs with L-menthol and lidocaine as HBA and a fatty acid as HBD exhibited superior performance compared to DESs consisting solely of L-menthol and lidocaine or those derived from fatty acids only. …”
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Influence of multiple décollement and cover rock rheology on the structural evolution of thin-skinned fold-and-thrust belts: insights from discrete element modelling by Eslamirezaei, Nazanin, Alavi, Seyed Ahmad, Nabavi, Seyed Tohid, Ghassemi, Mohammad Reza

“…The DE-modelling results compared with natural examples, as well as analogue and numerical models, show that our mechanical modelling can overall match thin-skinned fold-and-thrust belts with multiple décollements that present different structural style.…”
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Elicitation of Norwegian EQ-5D-5L values for hypothetical and experience-based health states based on the EuroQol Valuation Technology (EQ-VT) protocol by Knut Stavem, Tonya Moen Hansen, Ylva Helland, Liv Ariane Augestad, Kim Rand, Andrew Garratt

“…Using a sampling strategy supporting the collection of values for both hypothetical and experienced health states, the study will have the additional aim of assessing the feasibility of collecting experience-based values in accordance with the latest EQ-5D valuation study protocol, and comparing values with those given for hypothetical health states.Methods and analysis Multistage random sampling and quota-sampling will contribute to representativeness. …”
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Impact of copper stress in the intestinal barriers and gut microbiota of Chinese stripe-necked turtle (Mauremys sinensis) by Zeeshan Ali, Ijaz Khan, Muhammad Shahid Iqbal, Haitao Shi, Li Ding, Meiling Hong

“…Similarly, at genus level Romboutsia, Cetobacterium decreased, while Turicibacter and Sarcina significantly increases in copper-treated groups compared to the control. This indicating the unique properties of copper including its essentiality, reactivity, and accumulation enables it to profoundly impact gut bacteria, altering both their composition and function. …”
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A Criterion-based Approach for the Systematic and Transparent Extrapolation of Clinical Trial Survival Data by Gabriel Tremblay, Patrick Haines, Andrew Briggs

“…**Methods:** A criterion-based guide was devised to allow the accurate extrapolation and justification of survival estimates in a MBC study comparing eribulin (Halaven) monotherapy with treatment of their (patient’s) physician’s choice (TPC). …”
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Circulating microRNA panels for multi-cancer detection and gastric cancer screening: leveraging a network biology approach by Leila Kamkar, Samaneh Saberi, Mehdi Totonchi, Kaveh Kavousi

“…Methods This study aimed to identify biomarkers with high sensitivity and specificity for multiple and specific cancer screening. 972 Serum miRNA profiles were compared across thirteen cancer types and healthy individuals using weighted miRNA co-expression network analysis. …”
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Human&vehicle-in-the-loop test method in human factors research on automated vehicles: Conceptualization, realization, case-study, and lessons learned by Markus Steimle, Vanessa Stange, Mark Vollrath, Markus Maurer

“…We present selected results, compare them across the studies, and derive lessons learned from implementing and conducting the studies. …”
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CHOLINE TRANSPORTER-RELATED 4 (CTR4) Is Involved in Drought and Saline Tolerance in Rice by Yu Shicong, Luo Ruxian, Zheng Shuqin, Ning Jing, Shi Yuanzhu, Guo Daiming, Jia Liangmeng, Wang Sen, Xiao Guizong, Guo Pengwang, Li Yang, Ma Xiaoding

“…In knockout mutants, the total membrane lipid content, especially unsaturated fatty acids, was significantly reduced. Compared with the wild type, knockout mutants exhibited decreased membrane lipid stability under drought and salt stress, faster water loss, higher relative electrolyte leakage, and lower levels of proline and soluble sugars, leading to impaired tolerance to drought and salt stress. …”
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Do wolframin, P-glycoprotein, and GRP78/BiP cooperate to alter the response of L1210 cells to endoplasmic reticulum stress or drug sensitivity? by Simona Kurekova, Lucia Pavlikova, Mario Seres, Viera Bohacova, Jana Spaldova, Albert Breier, Zdena Sulova

“…The results of this paper demonstrated increased wolframin expression in P-gp positive cells compared to P-gp negative cells. Immunoprecipitation experiments revealed the formation of complexes between wolframin and ERS related proteins (PERK, ATF6 and GRP78/BiP), the amount of which varied depending on the presence of the above ER stressors. …”
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Evaluation of the efficacy of percutaneous spinal cord stimulation according to the single or double leads by Esra Ertilav, Osman Nuri Aydin

“…Abstract Aim The aim of the study was to compare the efficacy of single or double lead in percutaneous spinal cord stimulation (SCS). …”
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Investigating Two-dimensional Horizontal Mesh Grid Effects on the Eulerian Atmospheric Transport Model Using Artificial Neural Network by Amine Ajdour, Brahim Ydir, Houria Bouzghiba, Ishaq Dimeji Sulaymon, Anas Adnane, Dris Ben Hmamou, Kenza Khomsi, Jamal Chaoufi, Gábor Géczi, Radouane Leghrib

“…The findings are validated using monitoring data over different periods of 2010, 2016, and 2021 and compared with results from prior research. The initial aspect reveals: (1) Enhanced resolution increases the probability of accurate forecasts, particularly for ozone, with PM10 displaying less distinct patterns. (2) Spatial resolution has minimal impact on temperature and wind speed. (3) Planetary Boundary Layer Height (PBLH) exhibits higher sensitivity, influencing Land Use and Land Cover (LULC), primarily due to emissions, advocating for higher resolution. …”
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Differences and analogies in thyroid cancer discovered incidentally or by thyroid-related screening: a multicenter study by Laura Croce, Rosaria Maddalena Ruggeri, Camilla Virili, Carlo Cappelli, Marsida Teliti, Pietro Costa, Spyridon Chytiris, Antonio Nicocia, Francesca Coperchini, Maria Flavia Bagaglini, Flavia Magri, Alfredo Campennì, Mario Rotondi

“…Our aim was to assess the prevalence of thyroid-related disease (TD) versus incidental diagnosis (ID) pre-surgery reasons leading to TC diagnosis and to compare the two groups in terms of clinical characteristics, size and severity of TC at presentation and rate of non-thyroid cancers and cardiovascular/metabolic comorbidities. …”
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CRISPR/Cas genome editing for cotton precision breeding: mechanisms, advances, and prospects by Vijay Sheri, Harikrishnan Mohan, Phanikanth Jogam, Anshu Alok, Gulab Khan Rohela, Baohong Zhang

“…It allows precise and efficient manipulation within the cotton genome when compared with other genetic engineering tools. Current developments in CRISPR/Cas technology, including prime editing, base editing, and multiplexing editing, have expanded the scope of traits in cotton breeding that can be targeted. …”
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Optic Nerve Sheath Diameter in Predicting the Neurological Outcomes of Cardiac Arrest Survivors: A Systematic Review and Meta-analysis by Parisa Jafari Khouzani, Erfan Rahmani, Mehdi Rezaei, Sasan Pohrbagher Benam, Atousa Moghadam Fard, Reza Amani-Beni, Maziar Daneshvar, Faezeh Jalayer Sarnaghy, Naghme Masoomi Goodarzi, Ramila Abedi Azar, Amirhossein Mirbolook, Peyman Bashghareh, Elham Bibak, Babak Goodarzi, Zahra Salarinezhad, Reza Zahedpasha, Marzieh Hajizaman, Negar Pourhossein Rahmani, Azam Darvishi, Alireza Hadizadeh, Fatemeh Zandi, Ashkan Azizi, Armin Naderi, Sepideh Shah Hosseini, Asie Sanjary, Mozhdeh Mohammadi Virsoudi, Habibollah Afshang, Seyedsaber Mirabdali, Navid Fathalian, Pouria Momeni, Mahsan Valizade, Fateme Nozari, Hamed Ghorbani, Sanam Mohammadzadeh, Seyed Kiavash Sajadi, Azam Abdollahi, Mehrdad Farrokhi

“…Furthermore, meta-regression analysis revealed that ONSD measurement using CT scans is significantly associated with lower sensitivity and higher specificity compared to ultrasound (P = 0.009 and P = 0.01). …”
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Artificial Intelligence in Identifying Patients With Undiagnosed Nonalcoholic Steatohepatitis by Onur Baser, Gabriela Samayoa, Nehir Yapar, Erdem Baser

“…In addition to the baseline model, a gradient-boosted classification tree, naïve Bayes, and random forest model were created and compared using receiver operator characteristics, area under the curve, and accuracy. …”
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Association of blood pressure and left ventricular mass with subclinical coronary atherosclerosis by Weiting Huang, Calvin Chin, Rehena Sultana, Chirk Jenn Ng, Jonathan Jiunn Liang Yap, Enver De Wei Loh, Swee Yaw Tan, Siew Ching Kong, Khung K Yeo

“…Across all LVMI groups, higher BP was associated with the presence of CAC. Compared with individuals with normotensive BP and normal LVMI, those with normotensive BP and high LVMI had no increased risk of prevalent CAC (p=0.530); however, risk was progressively higher in those with hypertensive BP and normal LVMI (risk ratio (RR) 1.47, 95% CI 1.13 to 1.91), or hypertensive BP and high LVMI (RR 1.72, 95% CI 1.26 to 2.36).Conclusions In this healthy asymptomatic population, hypertension was the strongest risk factor for high LVMI and prevalent CAC. …”
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