Neutrophil gelatinase-associated lipocalin: a biochemical marker for acute kidney injury and long-term outcomes in patients presenting to the emergency department by Kah Hui Brian Teo, Swee Han Lim, Ying Hao, Yin Keong Daryl Lo, Ziwei Lin, Manish Kaushik, Chieh Suai Tan, Mohammed Zuhary Thajudeen, Choon Peng Jeremy Wee

“…Mean serum NGAL levels were raised (P < 0.001) in patients with AKI (670.0 ± 431.9 ng/dL) compared with patients without AKI (490.3 ± 391.6 ng/dL). …”
Get full text

Provocative tests of anal sphincter function correlate with symptoms and subtypes of faecal incontinence by John McLaughlin, Dipesh H Vasant, Asbjørn Mohr Drewes, Abhiram Sharma, Matthew Davenport, Edward Kiff, Karen Telford, Alexander O'Connor, Donghua Liao, Niels Klarskov

“…With FLIP, there was a trend towards reduced squeeze function in the urge group (pressure-diameter volume loop at 50 mL; p=0.295).Conclusions FLIP and AAR correlate better with FI symptoms compared with HRAM. Therefore, these provocative tests could be used to guide the management of FI in prospective studies.…”
Get full text

Eptinezumab-jjmr, a humanized monoclonal specific to Calcitonin Gene Related Peptide, for the preventive treatment of migraine in adults by Amnon A. Berger, Joseph Keefe, Cain W. Stark, Matthew Moore, Giovanni F. Ramírez, Julia R. Cucarola, Andrew H. Han, Alan D. Kaye, Latha Ganti

“…Further research is required to properly compare eptinezumab with existing pharmacotherapy and update guidelines on the appropriate combinations of therapies that are not available and the correct patient selection for each.…”
Get full text

Generating context-specific sports training plans by combining generative adversarial networks. by Juquan Tan, Jingwen Chen

“…Subjective evaluations reveal significant improvements in context-specific and applicability, with ratings averaging 4.8/5 compared to 3.9/5 for baseline models. The GAN framework effectively integrates multimodal data, demonstrating dynamic adaptability and high efficiency suitable for real-world applications. …”
Get full text

Reliability and Validity of the Y-balance Test in Young Adults with Chronic Low Back Pain by Yousef Alshehre, Khalid Alkhathami, Kelli Brizzolara, Mark Weber, Sharon Wang-Price

“… # Purpose To determine the inter-rater reliability of the YBT and to compare dynamic balance between young adults with CLBP and an asymptomatic group…”
Get full text

A woman’s place is in theatre: women’s perceptions and experiences of working in surgery from the Association of Surgeons of Great Britain and Ireland women in surgery working grou... by Maria Irene Bellini, Yitka Graham, Catherine Hayes, Roxanna Zakeri, Rowan Parks, Vassilios Papalois

“…The quantitative data were analysed through descriptive statistics and qualitative analysis was undertaken using a constant comparative analysis of the participants’ comments, to identify salient patterns (themes).Results A total of 81 female participants replied (42% response rate based on the Facebook group members), with 88% (n=71) perceiving surgery as a male-dominated field. …”
Get full text

Efficacy of vericiguat in patients with chronic heart failure and reduced ejection fraction: a prospective observational study by Yinge Zhan, Liu Li, Jie Zhou, Yishan Ma, Xuchong Guan, Suo Wang, Ya Chang

“…Additionally, Vericiguat significantly improved Peak Oxygen Consumption (from 14.24 ± 6.21 to 19.03 ± 4.87 ml/kg/min) and Anaerobic Threshold (from 10.48 ± 3.82 to 13.48 ± 3.31 ml/kg/min). Compared to the standard treatment group, the Vericiguat group demonstrated significantly higher Peak Oxygen Consumption, Anaerobic Threshold, and a lower Carbon Dioxide Equivalent Slope, with P values all below 0.05. …”
Get full text

Balancing selection at a wing pattern locus is associated with major shifts in genome-wide patterns of diversity and gene flow by Rodríguez de Cara, María Ángeles, Jay, Paul, Rougemont, Quentin, Chouteau, Mathieu, Whibley, Annabel, Huber, Barbara, Piron-Prunier, Florence, Ramos, Renato Rogner, Freitas, André V. L., Salazar, Camilo, Silva-Brandão, Karina Lucas, Torres, Tatiana Teixeira, Joron, Mathieu

“…We show that H. numata populations which carry the inversions as a balanced polymorphism show markedly distinct patterns of diversity compared to all other taxa. They show the highest genetic diversity and effective population size estimates in the entire clade, as well as a low level of geographic structure and isolation by distance across the entire Amazon basin. …”
Get full text

A biomechanical comparison of posterior malleolar fracture fixation using screws and locking plates in Trimalleolar fractures: a finite element study by Chih-Wei Chang, Yen-Nien Chen, Guan-Heng Jhong, Kuo-Chih Su, Chun-Ting Li

“…Abstract Background The aim of the study is to compare the mechanical stability of posterior malleolar fractures fixed with different screw types and locking plates in the management of trimalleolar ankle fractures using the finite element (FE) method. …”
Get full text

Improving the survival under gastric conditions of a potential multistrain probiotic produced in co-culture by Marcelo Fernando Valle-Vargas, Yesica Vanesa Rojas-Muñoz, Ruth Yolanda Ruiz-Pardo, Luisa Villamil-Díaz, María Ximena Quintanilla-Carvajal

“…Co-culture of L. lactis A12 with Priestia species improved significantly (p < 0.05) the antagonistic activity (10.41 mm) against S. agalactiae compared to mono-culture (7.70 mm). Our results suggested that was possible to produce a potential multistrain preparation in a lab bioreactor with high viability of L. lactis A12 (9.33 Log10 CFU/mL), high survival to gastric conditions (> 85%), and with antagonistic activity against fish pathogen. …”
Get full text

Respuesta de la vegetación a un rolado en la Provincia Fitogeográfica del Monte, Buenos Aires, Argentina by D.V. Peláez, F.R. Blazquez, H.D. Giorgetti, G.D. Rodríguez

“…Asimismo, sugieren que la reducción de la cobertura de las especies leñosas podría favorecer en el mediano o largo plazo (> 3 años) el incremento de la cobertura foliar y densidad de P. ligularis y N. tenuis. Un período de al menos un año sin pastoreo o con un pastoreo liviano después del rolado sería necesario para permitir la recuperación, principalmente de P. napostaense, de las gramíneas perennes deseables.…”
Get full text

The prognostic effect of immunohistochemical staining rates in patients with non–muscle-invasive bladder cancer by Aykut Demirci, Melike Ordu

“…Pathological data and survival rates were compared according to the staining rates. Statistical Analysis Used: Data obtained in the study were analyzed statistically with SPSS 22.0 (SPSS, Chicago, IL, USA). …”
Get full text

The Association between Ambient Fine Particulate Matter and Oral Neoplasm among Smokers and Betel Quids Chewers by Mei-Sheng Ku, Pallop Siewchaisakul, Amy Ming-Fang Yen, Chen-Yu Liu

“…After adjusting for sex, age, and behavior of betel quid chewing and cigarette smoking, we found that subjects from areas of higher levels of PM2.5 (≥ 35 µg m−3) had an increased risk of OPMD/OC and OC by 11% (aRR = 1.11; 95% CI: 1.09–1.13) and 55% (aRR = 1.55; 95% CI: 1.49–1.60) respectively, compared to those from areas of lower PM2.5 (< 35 µg m−3). …”
Get full text

Exploration of the quantitative-effectiveness association between acupuncture temporal parameters and chemotherapy-induced peripheral neuropathy in cancer patients: a dose-response... by Hao Tian, Qin Luo, Liuyang Huang, Liuyang Huang, Liuyang Huang, Guang Chen, Mingsheng Sun, Fanrong Liang

“…This study evaluated and compared the effectiveness of acupuncture treatments for CIPN.MethodsWe searched six databases from their inception to August 2024 to identify eligible randomized controlled trials (RCTs). …”
Get full text

Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis by Xiaoxue Wang, Longhao Cheng, Aijun Liu, Lihong Liu, Lili Gong, Guolin Shen

“…Metabolites were analyzed and identified using ultra high liquid chromatography coupled with Q Orbitrap mass spectrometry (UPLC-HRMS), followed by verification through a self-built database. Results Compared with HC participants, a total of 70 metabolites were identified as undergoing significant changes in NDMM. …”
Get full text

Movement Competency Screen: Rethinking the Rating by Justine Benoit-Piau, Mélanie Morin, Christine Guptill, Sylvie Fortin, Nathaly Gaudreault

“… # Results Internal consistency was higher for the 5-level scoring of the MCS items ($\alpha$=0.548) compared to the 3-level scoring system ($\alpha$=0.494). …”
Get full text

Investigation on the influencing mechanism and quantitative evaluation of stirred heat effect in high-speed mechanical seals by Xuezhong Ma, Xiaoxin Xiao

“…A three-dimensional thermohydrodynamic numerical model consisting of the fluid film, sealed chamber and sealing rings is developed to investigate the influencing mechanism of stirred heat by the comparative analyses of fluid flow, heat generation and transfer and evaluates its influence level by the parameterized analyses about the rotational speed, flushing flow rate, sealing pressure and sealing face structure. …”
Get full text

Screening, diagnosis, treatment and outcomes of developmental dysplasia of the hip in Brazilian population: a scoping review by Emily Schaeffer, Patricia Moreno Grangeiro, Patrícia Eduarda Conrado Martins Rocha Jaleca, Sheila Lam, Sana Arora, Daniel Frank Liggio

“…No study examined the effectiveness of specific screening programmes or compared their outcomes. The most common diagnostic methods were the Ortolani manoeuvre and ultrasonography using the Graf method. …”
Get full text

Isometric Knee Strength is Greater in Individuals Who Score Higher on Psychological Readiness to Return to Sport After Primary Anterior Cruciate Ligament Reconstruction by Barrie S. Sugarman, Zach B. Sullivan, Daniel Le, Carolyn Killelea, Mallory S. Faherty, Lee H. Diehl, Jocelyn R Wittstein, Jonathan C. Riboh, Alison P. Toth, Annunziato Amendola, Dean C. Taylor, Timothy C. Sell

“…The cohort was divided into two groups, high score (HS) and low score (LS), based on median ACL-RSI score, and performance on static and dynamic postural stability testing, lower extremity isokinetic and isometric strength testing, and single leg hop testing was compared between the groups using an independent samples t-test…”
Get full text

Assessment of point-of-care quantitative serum canine pancreatic lipase testing for diagnosing acute pancreatitis in dogs by Pin-Chen Liu, Pin-Chen Liu, Kendy Tzu-yun Teng, Kendy Tzu-yun Teng, Tsia-Lu Lin, Chi-Hsuan Sung, Tsun-Li Cheng, Chi-Chung Chou, Chi-Chung Chou

“…By day 3 of hospitalization, serum Vcheck CPL had significantly decreased in dogs with suspected acute pancreatitis compared to day 1. The ICC score between the clinical consensus score, Vcheck CPL, and SNAP ® cPL was 0.75, indicating good agreement. …”
Get full text