Ultrasensitive interferons quantification reveals different cytokine profile secretion in inflammatory myopathies and can serve as biomarkers of activity in dermatomyositis by Loïs Bolko, Loïs Bolko, Loïs Bolko, Céline Anquetil, Céline Anquetil, Alba Llibre, Solène Maillard, Damien Amelin, Karim Dorgham, Vincent Bondet, Océane Landon-Cardinal, Océane Landon-Cardinal, Océane Landon-Cardinal, Ségolène Toquet, Ségolène Toquet, Kuberaka Mariampillai, Samuel Malatre, Alexandrine Mahoudeau, Baptiste Hervier, Mathieu Rodero, Guy Gorochov, Darragh Duffy, Olivier Benveniste, Olivier Benveniste, Yves Allenbach, Yves Allenbach

“…Patients with active DM had a higher median IFN-α level (0.49 pg/ml [0.1-3.7]) compared with non-active patients (0.03 pg/ml [0.01-0.07] p<0.05). …”
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UHPLC-QTOF-MS/MS profiling, molecular networking, and molecular docking analysis of Gliricidia sepium (Jacq.) Kunth. ex. Walp. stem ethanolic extract and its gastroprotective effec... by Aya A. Wafaey, Seham S. El-Hawary, Osama G. Mohamed, Sahar S. Abdelrahman, Alaa M. Ali, Ahmed A. El-Rashedy, Mohamed F. Abdelhameed, Farid N. Kirollos

“…Histopathological examination revealed significant improvements in gastric tissue morphology in GSS-treated groups compared to the control group. Molecular docking studies indicated potential interactions between GSS ethanolic extract compounds and various target proteins involved in oxidative stress, inflammation, and gastric protection in gastritis. …”
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Effect of prenatal multiple micronutrient supplementation on birth weight in Ethiopia: protocol for a pragmatic cluster-randomised trial by Joanna Schellenberg, Charles Opondo, Tanya Marchant, Lars Åke Persson, Masresha Tessema, Atkure Defar, Alemneh Kabeta Daba, Girum Taye, Senait Alemayehu, Elias Asfaw, Anene Tesfa, Bedasa Tessema, Kalkidan Zenebe

“…A 2019 meta-analysis reported a mean increase of 35 g in birth weight among newborns of women who took multiple micronutrient supplements in pregnancy compared with those who took iron-folic acid. Responding to that evidence, the government of Ethiopia decided to implement a 21 district pilot of the use of multiple micronutrient supplementation in routine antenatal care and requested an evaluation of implementation outcomes, including on birth weight.Methods and analysis A pragmatic, facility-based, randomised trial is being conducted in 42 districts over five regions of Ethiopia between January 2023 and December 2024. …”
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Forensic Assessment of Alcohol Intoxication in Cases of Fatal Road Traffic Accidents in Lithuania by Beata Kirstukaitė, Akvilė Paškauskienė, Sigitas Chmieliauskas, Sigitas Laima, Diana Vasiljevaitė, Jurgita Stasiūnienė

“…. – 5 a. m.) 2.28 ± 0.91, comparing to in afternoon hours (12 p. m. – 5 p. m.) 1.49 ± 0.99, evening hours (5 p. m. – 9 p. m.) 2.10 ± 0.73 and morning hours (5 a. m. – 12 p. m.) 1.94 ± 1.00. …”
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Proximity extension assay revealed novel inflammatory biomarkers for follicular development and ovarian function: a prospective controlled study combining serum and follicular flui... by Chong Wang, Ying Feng, Yu Chen, Xianhua Lin, Xiangjuan Li

“…Olink proteomic proximity extension assay (PEA) technology was used to compare the differentially expressed proteins (DEPs), and patients were divided into two subgroups—the normal ovarian reserve (NOR) group and the DOR group—for further bioinformatics analysis and verification by enzyme-linked immunosorbent assay (ELISA).ResultsIn total, 16 DEPs were detected between the mature group and the immature group (FF), and 11 DEPs were detected between the ovulation group and the menstruation group (serum). …”
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Forecasting mental states in schizophrenia using digital phenotyping data. by Thierry Jean, Rose Guay Hottin, Pierre Orban

“…In conclusion, when using performance metrics that properly account for class imbalance, ordinal forecast models demonstrated comparable performance to the prevalent binary classification approach without losing valuable clinical information from self-reports, thus providing richer and easier to interpret predictions.…”
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Exploring RNA cargo in extracellular vesicles for pleural mesothelioma detection by Agnieszka Kraft, Michaela B. Kirschner, Vanessa Orlowski, Manuel Ronner, Caroline Bodmer, Valentina Boeva, Isabelle Opitz, Mayura Meerang

“…To investigate whether these markers could serve as biomarkers for PM detection in blood, we compared the RNA content of PM-EVs with the cargo of EVs isolated from the plasma of healthy donors (publicly available data). …”
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Assessing hemorrhagic risks in combination therapy: implications of angiogenesis inhibitors and immune checkpoint inhibitors by Yuhui Yang, Yuhui Yang, Yuhui Yang, Pingping Long, Pingping Long, Ying Tuo, Ying Tuo, Xiaoxiao Wang

“…To assess whether the hemorrhage risk is higher with combination therapy compared to monotherapy, additive and multiplicative models were employed to evaluate the interactions between combination and single-agent treatments.ResultsThe combination of AGIs and ICIs significantly increased the risk of hemorrhagic adverse events, particularly tumor and pulmonary hemorrhage. …”
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Benchmarking LLM chatbots’ oncological knowledge with the Turkish Society of Medical Oncology’s annual board examination questions by Efe Cem Erdat, Engin Eren Kavak

“…This study aims to evaluate and compare the oncological knowledge of four LLMs using standardized board examination questions. …”
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Longitudinal Invariance Testing Of The Knee Injury Osteoarthritis Outcome Score For Joint Replacement Scale (KOOS-JR) by Alexandra Dluzniewski, Caleb Allred, Madeline P Casanova, Jonathan D Moore, Adam C Cady, Russell T Baker

“…Latent group means were compared with statistical significance set at α ≤ .05 and Cohen’s d effect size as d = 0.2 (small), d = 0.5 (medium), and d = 0.8 (large)…”
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Self-reported sleep in late pregnancy in relation to birth size and fetal distress: the E Moe, Māmā prospective cohort study by Laura D Howe, Sarah-Jane Paine, T Leigh Signal, Bronwyn Sweeney, Monique Priston, Diane Muller, Kathy Lee, Mark Huthwaite, Philippa Gander

“…Many of the associations we observed were considerably stronger in Māori compared with non-Māori women.Conclusions We did not find evidence of previously reported associations between snoring and SGA. …”
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Association of adenylate cyclase activity in vasopressor-type neurally mediated syncope based on the α2b-AR gene. by Tomoyoshi Komiyama, Kengo Ayabe, Kunzo Orita, Ayumi Sasaki, Yuka Kitamura, Hideyuki Matsuzawa, Teppei Yamashita, Eiichiro Nagata, Yasuhiro Kanatani, Koichiro Yoshioka

“…Additionally, patients with the Glu9/12 heterotype were found to have a higher risk of syncope after prolonged standing compared to those with the Glu12/12 homotype. These results suggest that patients with the Glu12/12 homotype exhibit elevated AC activity levels, which may help increase blood pressure to prevent syncope. …”
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La actividad peroxidasa en caña de azúcar (Saccharum spp): evolución temporal de la reacción y su posible rol en la resistencia a la roya marrón (Puccinia melanocephala, H&P Sydow)... by C.R. MACHADO ASSEFH, N.G. COLLAVINO, M. DAZ, M.I. POCOVÍ, J. MARIOTTI

“…La roya marrón de la caña de azúcar, causada por Puccinia melanocephala, es una enfermedad foliar de preocupación en casi todos los países donde se cultiva la caña de azúcar. …”
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Psychosocial work characteristic profiles and health outcomes in registered nurses at different stages of their careers: a cross-sectional study by Katri Lönnqvist, Timo Sinervo, Anu-Marja Kaihlanen, Marko Elovainio

“…The low strain/high support profile group and the moderate strain/high support profile group had statistically better self-rated health (p = < 0.001), less psychological distress (p = < 0.001) and less sleep problems (p = < 0.001) compared to the high strain/low support profile group. …”
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Prospective Study of Surgical Management of Midshaft Clavicle Fractures by Pawan Kumar, Mritunjay Kumar

“…There was no major complication, one patient had superficial infection, deep infection in 1 case, nonunion in 1 case and plate breakage in one patient. Results were compared with cases treated conservatively. Conclusion: In the present era of competition, cosmesis and advancement with least morbidity and excellent results is required. …”
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INTEGRATION OF THE BALTIC STOCK MARKETS WITH GLOBAL MARKETS DURING THE PREVIOUS DECADE by Anmar Pretorius

“…The preliminary analysis compares the economic structures of the three domestic economies, the industry contributions of the stock exchanges, and the major international countries investing in the three stock markets. …”
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Comparison of Modified Biophysical Profile with Doppler Ultrasonographic Analysis in Determining Fetal well Being in the Third Trimester by Kadir Bakay, Ahmet Varolan, Ali Yazgan, Atif Akyol, İnci Davas

“… OBJECTIVES: In this study we aim to compare modified biophysical profile with Doppler ultrasonographic analysis in determining fetal well being in the third trimester. …”
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Pengembangan Metode Interpolasi Splin Kubik Terapit dan Aplikasinya pada Masalah Pelacakan Trajektori Objek by Elvathna Syafwan, Mahdhivan Syafwan, Shandy Tresnawati

“…In particular, this problem is examined for second-order clamped cubic spline, and the interpolated results are compared with those for natural and first-order clamped cubic splines. …”
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Agreement Between Isokinetic Dynamometer and Hand-held Isometric Dynamometer as Measures to Detect Lower Limb Asymmetry in Muscle Torque After Anterior Cruciate Ligament Reconstruc... by Angelica Ivarsson, Anna Cronström

“…Cross-tabulations showed that the hand-held dynamometer detected a significantly larger number of participants with abnormal flexion torque limb symmetry index compared to the isokinetic dynamometer. # Conclusion The wide limits of agreements and Cohen's Kappa coefficients values revealed insufficient agreement between the measurements taken with the two instruments, indicating that the instruments should not be used interchangeably. …”
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Cost Effectiveness Analysis of Eribulin Mesylate as a Treatment for Metastatic Breast Cancer in Spain: Management in the Later Line of Therapy by Gabriel Tremblay, Unnati Majethia, Ilias Kontoudis, Jesús De Rosendo

“…The study objective was to compare the cost-effectiveness of eribulin in Spain as a second-line treatment for HER2-negative MBC with its current status as a third-line treatment for patients who have received capecitabine. …”
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