A comparison of the acute effects of high intensity interval training and moderate intensity continuous training on working memory and emotional state in adolescent women with subt... by Shiwei Yuan, Lili Lin, Libin Liu, Xinyuan Zhang, Qian Gu

“…However, it is not yet clear what kind of exercise intensity is suitable for individuals with subthreshold depression. …”
Get full text

Exploring cement Production's role in GDP using explainable AI and sustainability analysis in Nepal by Ramhari Poudyal, Biplov Paneru, Bishwash Paneru, Tilak Giri, Bibek Paneru, Tim Reynolds, Khem Narayan Poudyal, Mohan B. Dangi

“…In cross-validation, the Extra Trees model with a mean cross-validation R2 score of 0.93 and a low standard deviation of 0.04 proved to be the best-performing model, as evidenced by lower differences in R2 score across folds compared to other models, demonstrating its high predictive performance. …”
Get full text

Unraveling the association and regulatory role of miR-146b-5p in coronary artery disease by Xiaozhu Ma, Shuai Mei, Yi He, Qidamugai Wuyun, Li Zhou, Ziyang Cai, Qiushi Luo, Yi Wen, Jiangtao Yan

“…We found that miR-146b-5p was significantly increased in PBMCs of patients with CAD compared with the control group. Binary logistic regression revealed that miR-146b-5p was associated with CAD. …”
Get full text

The Case for Brutalist Honesty in Medical Education by Markle DT

“…D Thomas Markle Department of Family and Community Medicine, School of Medicine, University of New Mexico, Albuquerque, NM, USACorrespondence: D Thomas Markle, Department of Family & Community Medicine, UNM School of Medicine, MSC08 4720, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA, Email [email protected]: The assumption of a prioi trust between students and institutions of medical education is anachronistic and promotes both unnecessary student anxiety and the adoption of hidden curriculums to offset perceived risk due to a lack of transparency. Compared to the past, students now have access to a wealth of outside data to evaluate their curricular progress and career prospects against, and yet institutions are lagging behind in openly disclosing information related to metrics of student success (course passing rates, number of repeat students per class, Step 1 pass rate, etc.) that would engender trust and afford students greater agency in their academic decisions.Approach: In developing a new academic counseling office, the author deployed a method of using brutalist honesty as a means of student support, both in terms of answering all curriculum questions truthfully no matter the topic and with individualized data analytics to provide objective evidence as to student performance progress. …”
Get full text

Missing The Forest For The Trees: A Lack Of Upper Extremity Physical Performance Testing In Sports Physical Therapy by Matthew L Gauthier, Casey A Unverzagt, Luciana De Michelis Mendonça, Amee L Seitz

“…A secondary aim was to compare practice patterns of clinicians with sports physical therapy specialty certification to clinicians without…”
Get full text

Liver and Nutrition. An Optimal Diet for Non-Alcoholic Fatty Liver Disease by M. V. Mayevskaya, V. T. Ivashkin

“…Food produced from whole grain has a lower energy potential as compared to that produced from refined grain. Meat contains various nutrients, such as proteins, iron, zinc, B12 vitamin, as well as sodium, saturated fatty acids and cholesterol, which serve as risk factors for the development of NAFLD and other cardio-metabolic disorders. …”
Get full text

Enhancing Arabic text-to-speech synthesis for emotional expression in visually impaired individuals using the artificial hummingbird and hybrid deep learning model by Mahmoud M. Selim, Mohammed S. Assiri

“…The performance validation of the AMCDD-AHODL approach portrayed a superior accuracy value of 95.80 % compared to the existing ML and DL models. Therefore, the AMCDD-AHODL technique is applied for the early identification of various kinds of depression that can decrease the distress from the illness and the stigma related to mental health problems.…”
Get full text

Accounting for racial bias and social determinants of health in a model of hypertension control by Yang Hu, Nicholas Cordella, Rebecca G. Mishuris, Ioannis Ch. Paschalidis

“…Black patients face a 4.7 $$\times$$ × higher False Positive Rate (FPR) and a 0.58 $$\times$$ × lower False Negative Rate (FNR) compared to White patients. Decision threshold differentiation was implemented to equalize FNR. …”
Get full text

Trajectory of the arterial-alveolar oxygen gradient in COPD for a decade. by Kazuma Nagata, Susumu Sato, Kiyoshi Uemasu, Naoya Tanabe, Atsuyasu Sato, Shigeo Muro, Toyohiro Hirai

“…Retrospective tracking from the initiation of long-term oxygen therapy (LTOT) revealed significant increases in A-aDO2 from 5 years prior to LTOT initiation in the CRF group when compared to the non-CRF group.<h4>Conclusions</h4>An increasing trend in A-aDO2 may be a significant sign for the future development of CRF. …”
Get full text

Effects of nano-selenium and/or vitamin E supplementation on growth performance, antioxidant status, histopathology and resistance to Aspergillus flavus in Nile tilapia (Oreochromi... by Walaa K. Bazina, Wesam A. Tawfik, Nadia A. Abd Elghany, Saadea Saadony, Zulhisyam Abdul Kari, Muna Omer Alamoudi, Mohamed Y. M. Aly, Abuelhassan Elshazly Younis, Roshmon Thomas Mathew, Moaheda E. H. Eissa, Mohammad Bodrul Munir, Saadiah Ibrahim, Ismail Yousef, Yusuf O. H. Omar, El-Sayed Hemdan Eissa, Heba E. Abd Elnabi

“…A slight but significant increase (P  < 0.05) in whole-body composition was observed in all treatment groups compared to the control. Biochemical parameters, serum digestive enzyme activity, and antioxidant levels improved significantly with dietary supplementation. …”
Get full text

Evolution of CFD as an engineering science. A personal perspective with emphasis on the finite volume method by Runchal, Akshai Kumar

“…Computational Fluid Dynamics—CFD for short—is a comparatively recent development that has made a significant impact in engineering sciences. …”
Get full text

TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

“…Notably, HK2 levels were markedly higher in pancreatic cancer tissues compared to adjacent normal tissues. TWIST1 was found to directly bind and interact with HK2, showing co-localization in the cytoplasm of PDAC cells. …”
Get full text

Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 by Henry Chen, Henry Chen, Adam L. Numis, Adam L. Numis, Renée A. Shellhaas, John R. Mytinger, Debopam Samanta, Rani K. Singh, Rani K. Singh, Shaun A. Hussain, Danielle Takacs, Kelly G. Knupp, Li-Rong Shao, Carl E. Stafstrom

“…Among children with trisomy 21 and IESS, treatment with ACTH or oral corticosteroids may yield higher response rates compared with vigabatrin. However, supporting data are largely from single-center, retrospective cohort studies.MethodsLeveraging the multi-center, prospective National Infantile Spasms Consortium (NISC) database, we evaluated the efficacy of first-line (standard) treatments for IESS in children with trisomy 21. …”
Get full text

Association of only-child status and household pet ownership with attention-deficit/hyperactivity disorder among Chinese preschool children: a population-based study by Yuying Zhang, Shuangyan Qiu, Vivian Yawei Guo, Weiqing Chen, Xiaomei Han, Weikang Yang

“…Only-child status was associated with an increased risk of ADHD [adjusted odds ratio: 1.30 (95%CI: 1.23–1.38). Compared to children without a pet (cats or dogs) at ages 0–3 years, pet ownership at ages only 0–1 year, only 1–3 years, and both ages were associated with increased odds of ADHD: 1.59 (1.30–1.95), 1.58 (1.28–1.93), and 1.66 (1.42–1.92), respectively, after controlling for potential confounders. …”
Get full text

Quantum size effects and tailoring the electron energy levels in semiconductors: comparison study on Al x Ga 1-x As and Ga x In 1-x As quantum wires by M. K. Abu-Assy, Fatin Fadhel Mahmood, Z. A. El-Wahab

“…The electron energy levels in rectangular AlxGa1-xAs and GaxIn1-xAs quantum wires with infinite potential barrier were calculated at different x values and different cross-section areas to explore the role of dopant and compared with the cylindrical shape. The calculations of the electron confinement energy in the first and second energy levels indicate that the energy value in cylindrical quantum wire is less than its value in rectangular one while for E 3 the energy value in cylindrical quantum wire is larger than its value in rectangular one for all values of x. …”
Get full text

Host 3' flap endonuclease Mus81 plays a critical role in trimming the terminal redundancy of hepatitis B virus relaxed circular DNA during covalently closed circular DNA formation. by Hu Zhang, Quanxin Long, Yuanjie Liu, Alexander L Marchetti, Cheng-Der Liu, Ning Sun, Haitao Guo

“…The production of HBV rcDNA and cccDNA in HepDES-C1822G cells was comparable to wt levels. Next-generation sequencing (NGS) analysis revealed that the positive (+) strand DNA of rcDNA and both strands of cccDNA predominantly carried the wt nt1822 residue, indicating that the 5' TR of (-) strand DNA serves as the template during rcDNA replication, forming a duplex with the (+) strand DNA, while the 3' TR forms a flap-like structure, which is subsequently removed during cccDNA formation. …”
Get full text

Adaptive Neuro-Fuzzy Inference System guided objective function parameter optimization for inverse treatment planning by Eduardo Cisternas Jiménez, Fang-Fang Yin, Fang-Fang Yin, Fang-Fang Yin

“…The system evaluates dosimetric parameters and compares dose distributions, dose-volume histograms, and dosimetric statistics between the conventional FIS and ANFIS. …”
Get full text

Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin... by EA Obichi, CC Monago, DC Belonwu

“…CA significantly (p<0.05) increased the SOD and CAT activities, PCV, and Hb concentrations of the treated diabetic rats (TDR) while the TBARS was significantly (p<0.05) decreased compared to the diabetic control (DC). Our findings suggest that CA exhibited reversal effects on these selected oxidative and haematologic markers in rats which were previously damaged by HFD and STZ.…”
Get full text

The effect of prednisolone ingestion and acute exercise on lipocalin-2 and its variants in young men: a pilot randomised crossover study by Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger

“…Regardless of treatment, LCN2, C87A, R81E, and hLCN2 increased immediately after exercise compared with baseline (all p < 0.04). C87A, but not LCN2 or its other variants, remained elevated at 180 min post-ex (p = 0.007). …”
Get full text

Tangeretin offers neuroprotection against colchicine-induced memory impairment in Wistar rats by modulating the antioxidant milieu, inflammatory mediators and oxidative stress in t... by Olalekan Bukunmi Ogunro, Mojisola Esther Karigidi, Gideon Ampoma Gyebi, Areej Turkistani, Ahmad H. Almehmadi

“…This study evaluated the impact of tangeretin in mitigating cognitive dysfunction and oxidative stress induced by colchicine in rats, comparing its efficacy with donepezil hydrochloride. …”
Get full text