Fecal microbiota transplantation modulates jejunal host-microbiota interface in weanling piglets by Shankumar Mooyottu, Muhammed Shafeekh Muyyarikkandy, Farnaz Yousefi, Ganwu Li, Orhan Sahin, Eric Burrough, Joy Scaria, Brett Sponseller, Alejandro Ramirez

“…Results The jejunal microbiota showed a significant increase in alpha diversity in the third week post-FMT compared with the ileum and colon. FMT significantly enriched the jejunal microbiota composition, while multiple bacterial genera were specifically lacking in control weanling piglets. …”
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Sequence-based GWAS in 180,000 German Holstein cattle reveals new candidate variants for milk production traits by Ana-Marija Križanac, Christian Reimer, Johannes Heise, Zengting Liu, Jennie E. Pryce, Jörn Bennewitz, Georg Thaller, Clemens Falker-Gieske, Jens Tetens

“…The top potential causal variants determined with fine-mapping explained a large percentage of genetic variance compared to random ones; 178 variants explained 11.5%, 104 explained 7.7%, and 68 variants explained 3.9% of the variance for MY, FY, and PY, respectively, demonstrating the potential for causality. …”
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Examining the Impact of Certificate of Need Laws on the Utilization and Reimbursement of Cataract Surgeries Among Medicare Beneficiaries by Alvina Liang, Jennifer L. Lindsey

“…However, little is known about the impact of CON laws on cataract surgery utilization and reimbursement. **Objectives:** To compare utilization and reimbursement for non-complex cataract surgery in CON and non-CON states. …”
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Intravenous versus subcutaneous tocilizumab in Takayasu arteritis: multicentre retrospective study by Patrice Cacoub, Arsène Mekinian, David Saadoun, Pavel I Novikov, Savino Sciascia, Corrado Campochiaro, Olivier Fain, Ilya Smitienko, Nicolas Schleinitz, Patrick Jégo, Francesco Muratore, Carlo Salvarani, Elena Galli, Sabine Berthier, Marc Lambert, François Maurier, Isabelle Kone-Paut, Sergey Moiseev, Masataka Kuwana, Alexandre Belot, Martin Michaud, Francis Gaches, Achille Aouba, Xavier Puechal, Karim Sacre, Tiphaine Goulenok, Alessandro Tomelleri, Thomas Sené, Elena Marina Baldissera, Luigi Boiardi, Abid Awisat, Ygal Benhamou, Vahan Mukuchyan, Mathieu Vautier, Azeddine Dellal, Lucie Biard, Julie Seguier, José Hernández-Rodríguez, Olivier Espitia, Sebastien Humbert, Guillaume Denis, Nolan Hassold, Dagna Lorenzo, Helene Munoz Pons, Jean Baptiste Gaultier, Le Mouel Edwige, Antoinette Perlat, Bertrand Lioger, Jonathan Broner, Virginie Dufrost, Faten Frikha, Alexandra Audemard-Verger, Pascal Woaye-Hune, Pierre Zeminsky, Moya Alvarado, Matheus Vieira, Alberto Lo Gullo

“…Objectives In this large multicentre study, we compared the effectiveness and safety of tocilizumab intravenous versus subcutaneous (SC) in 109 Takayasu arteritis (TAK) patients.Methods We conducted a retrospective multicentre study in referral centres from France, Italy, Spain, Armenia, Israel, Japan, Tunisia and Russia regarding biological-targeted therapies in TAK, since January 2017 to September 2019.Results A total of 109 TAK patients received at least 3 months tocilizumab therapy and were included in this study. …”
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Implementing adaptive e-learning for newborn care in Tanzania: an observational study of provider engagement and knowledge gains by Peter Andrew Meaney, Christine Lynn Joyce, Ambrose Agweyu, Joseph R Mwanga, Marc Berg, Adolfine Hokororo, Hanston Ndosi, Alex Dahlen, Theopista Jacob, Florence Salvatory Kalabamu, Rishi Mediratta, Boris Rozenfeld, Zachary Haines Smith, Neema Chami, Namala Mkopi, Castory Mwanga, Enock Diocles

“…Higher baseline conscious-competence (OR 31.6 (95% CI 5.8 to 183.5)) and being a nursing officer (aOR: 5.6 (95% CI 1.8 to 18.1)), compared with medical officer, were associated with initial learning completion or persistent activity.Conclusion aESNC reach was high in a population of frontline providers across diverse levels of care in Tanzania. …”
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CSF shunts as conduits for metastasis: is there a discrepancy between retrograde and antegrade spread? by Andrea Cuschieri, Robert Pisani, Shawn Agius

“…The aim of this systematic review was to comparatively assess the nature of antegrade and retrograde metastatic spread along CSF shunts. …”
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The agronomic mechanism of root lodging resistance and yield stability for sweet corn in response to planting density and nitrogen rates at different planting dates by Qinggan Liang, Qinggan Liang, Qinggan Liang, Qinggan Liang, Hailong Chang, Hailong Chang, Hongrong Chen, Hongrong Chen, Qingdan Wu, Qingdan Wu, Yuanxia Qin, Zhuqing Wang, Gang Wang, Xuhui Li, Weiwei Chen, Jiantao Wu, Jiantao Wu, Qinnan Wang, Jianqiang Wang, Jianqiang Wang

“…The maximum yield output was achieved in the plants under N150D25 via a significant increase in individual ear fresh weight, kernel number per row, and grain number per ear via path analysis. Compared with that of N200D30 (local field management), the yield of N150D25 plants increased by 22.33%–30.00% during the three growing seasons. …”
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CX3CR1+ age-associated CD4+ T cells contribute to synovial inflammation in late-onset rheumatoid arthritis by Mitsuhiro Akiyama, Sohma Wakasugi, Keiko Yoshimoto, Koichi Saito, Sho Ishigaki, Risa Inukai, Yoshiyuki Matsuno, Waleed Alshehri, Yasushi Kondo, Yuko Kaneko

“…Late-onset rheumatoid arthritis (LORA) exhibits unique characteristics compared to other RA forms, suggesting distinct immunological mechanisms. …”
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Quantifying the tumour vasculature environment from CD-31 immunohistochemistry images of breast cancer using deep learning based semantic segmentation by Tristan Whitmarsh, Wei Cope, Julia Carmona-Bozo, Roido Manavaki, Stephen-John Sammut, Ramona Woitek, Elena Provenzano, Emma L. Brown, Sarah E. Bohndiek, Ferdia A. Gallagher, Carlos Caldas, Fiona J. Gilbert, Florian Markowetz

“…We also performed a 3D histology analysis on a separate tumour sample as a proof of principle, providing a more comprehensive visualization of vasculature morphology compared to the standard 2D cross-section of a tissue sample. …”
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SkelETT—Skeleton-to-Emotion Transfer Transformer by Pedro Victor Vieira Paiva, Josue Junior Guimaraes Ramos, Marina Gavrilova, Marco Antonio Garcia de Carvalho

“…Transfer performance is measured on the BoLD body emotion recognition dataset. Compared to the state-of-the-art, we report significant gains in accuracy (<inline-formula> <tex-math notation="LaTeX">$\approx ~34$ </tex-math></inline-formula>% higher), training time (<inline-formula> <tex-math notation="LaTeX">$\approx ~50$ </tex-math></inline-formula>% less), and model complexity reduction (<inline-formula> <tex-math notation="LaTeX">$\approx ~80$ </tex-math></inline-formula>% less trainable parameters).…”
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The predicted value for venous thromboembolism based on a modified model of caprini combined with fasting blood glucose and D-dimer: a retrospective study by Ping Wang, Yusi Yang, Lin Zheng, Xiaotong Qi, Sheng Yan, Honglin Dong

“…Therefore, we constructed three models. caprini + D-dimer, caprini + FBG, and caprini + D-dimer + FBG. We compared them with caprini alone. Caprini + FBG + D-dimer showed the greatest ROC (0.784, 95% CI 0.730–0.837, Delong test P = 0.002 vs. …”
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Prediction of mechanical characteristics of shearer intelligent cables under bending conditions. by Lijuan Zhao, Dongyang Wang, Guocong Lin, Shuo Tian, Hongqiang Zhang, Yadong Wang

“…The results show that, compared to other predictive models, the proposed model achieves reductions in Mean Squared Error (MSE), Root Mean Squared Error (RMSE), and Mean Absolute Error (MAE) to 0.0002, 0.0159, and 0.0126, respectively, with the coefficient of determination (R2) increasing to 0.981. …”
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The mcpC mutant of Salmonella enteritidis exhibits attenuation and confers both immunogenicity and protective efficacy in mice by Lu Zhang, Li Chen, Xuqiang Zhang, Yang Li, Qingfeng Zheng, Yun Li, Ning Li, Qiumei Shi, Yanying Zhang, Tonglei Wu

“…Furthermore, the immunogenicity of ΔmcpC was analyzed in mice by measuring specific IgG and SIgA antibody levels, lymphocyte proliferation, cytokine expression, and the protective efficacy of ΔmcpC vaccination.ResultsCompared to the wild-type strain, ΔmcpC exhibited no significant changes in biofilm formation or adhesion to Caco-2 cells. …”
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Association between cadherin-related family member 3 rs6967330-A and human rhinovirus-C induced wheezing in children by Hanhaoyu Fu, Ri De, Yu Sun, Yao Yao, Runan Zhu, Dongmei Chen, Yutong Zhou, Qi Guo, Linqing Zhao

“…More patients infected with HRV-C had history of allergy (P = 0.004), family history of asthma (P = 0.001), wheezing (P = 0.005) and asthma (P = 0.001) than those infected with HRV-A or HRV-B, while patients infected with HRV-C were less likely to have older siblings compared to those infected with HRV-A (P = 0.014). …”
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Center of Pressure Velocity and Dynamic Postural Control Strategies Vary During Y-Balance and Star Excursion Balance Testing by Kristen L Jagger, Brent Harper

“… # Conclusion External proprioceptive feedback from the reach indicator improved DPC during the YBT and MYBT when compared to the MSEBT. Sagittal plane COP velocities were reduced when external proprioceptive feedback from the reach indicator was present, while frontal plane COP velocities were not affected in this group of participants…”
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Ethnoracial disparities in childhood growth trajectories in Brazil: a longitudinal nationwide study of four million children by Helena Benes Matos da Silva, Rita de Cássia Ribeiro-Silva, Juliana Freitas de Mello e Silva, Irina Chis Ster, Poliana Rebouças, Emanuelle Goes, Maria Yury Ichihara, Andrêa Ferreira, Julia M. Pescarini, Rosemeire Leovigildo Fiaccone, Enny S. Paixão, Maurício L. Barreto

“…Conclusion We observed racial disparities in nutritional status and childhood growth trajectories, with children of Indigenous mothers presenting less favorable outcomes compared to their White counterparts. The strengthening of policies aimed at protecting Indigenous children should be urgently undertaken to address systematic ethnoracial health inequalities.…”
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A lightweight wheat ear counting model in UAV images based on improved YOLOv8 by Ruofan Li, Xiaohua Sun, Kun Yang, Zhenxue He, Zhenxue He, Xinxin Wang, Xinxin Wang, Chao Wang, Chao Wang, Bin Wang, Fushun Wang, Fushun Wang, Hongquan Liu, Hongquan Liu

“…Experimental results demonstrate that the improved PSDS-YOLOv8 model achieves Mean Average Precision(mAP) 50 and mAP50:95 scores of 96.5% and 55.2%, which increases by 2.8% and 4.4%, while the number of parameters is reduced by 40.6% in comparison with the baseline YOLOv8 model. Compared to YOLOv5, YOLOv7, YOLOv9, YOLOv10, YOLOv11, Faster RCNN, SSD, and RetinaNet, the improved model demonstrates superior accuracy and fewer parameters, exhibiting the best overall performance. …”
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Discrepancies in safety reporting for chronic back pain clinical trials: an observational study from ClinicalTrials.gov and publications by Nick Boyne, Alison Duke, Jack Rea, Adam Khan, Alec Young, Jared Van Vleet, Matt Vassar

“…Only 4 (10%) publications fully reported adverse events (AEs) without discrepancies, while 36 (90%) contained at least one inconsistency compared to ClinicalTrials.gov. Discontinuation due to AEs was explicitly reported in 24 (60%) of ClinicalTrials.gov entries and in 30 (75%) of publications, with discrepancies in 16 trials (40%). …”
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Worth the effort? A practical examination of random effects in hidden Markov models for animal telemetry data by Brett T. McClintock

“…I performed an extensive simulation study comparing the performance of a suite of fixed and random effect models for individual heterogeneity in the hidden state process of a two‐state HMM. …”
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Evaluating causes and gestures: source-related and crossmodal features in the perception of environmental sounds by Sven-Amin Lembke

“…Manipulated sounds that emphasized gesture salience yielded only slight improvements of identification accuracy compared to original environmental sounds. Participants were more confident in identifying the source/cause in sounds containing pitch gestures than those containing loudness gestures, while lexical and semantic diversity in describing underlying materials (source) and actions (cause) varied considerably. …”
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