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3781
Role of phytochemicals in cardiovascular disease management: Insights into mechanisms, efficacy, and clinical application
Published 2025-02-01“…Multiple mechanisms, such as combating oxidative stress, controlling inflammation, enhancing the function of endothelial cells, regulating lipid levels, preventing platelet clot formation, and managing blood pressure, have demonstrated the cardiovascular benefits of these phytochemicals. …”
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3782
Modern air defense methods and countermeasures for use in operational-tactical missiles
Published 2024-06-01“…This necessitates a diverse array of defense systems, ranging from integrated military units to specialized onboard apparatus tailored for individual combat vehicles. Analysis extends to hypothetical attack scenarios on strategically vital installations, considering the deployment of military units equipped with radar systems, air defense forces, and aviation resources. …”
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3783
Towards equitable carbon responsibility: Integrating trade-related emissions and carbon sinks in urban decarbonization
Published 2025-03-01“…Our proposed CMR framework provides a robust basis for incentivizing coordinated mitigation efforts, promoting decarbonization in supply chains and enhancement of urban carbon sink capacities.…”
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3784
The molecular receptor NKBB enhances the persistence and anti-hepatocellular carcinoma activity of GPC3 CAR-T cells
Published 2025-02-01“…Our study showed that the molecular receptor NKBB conferred GPC3 CAR-T cells with enhanced migration and infiltration abilities towards HCC, higher central memory T (TCM) cell proportion and proliferation capacity, and reduced exhaustion level. GC3328z-NKBB CAR-T cells exhibited improved cytotoxicity against HCC cells and prolonged persistence. …”
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3785
Changes in Drop and Repeated Jump Ground Reaction Forces After a 10-Week Offseason Strength and Conditioning Program in Division I American Football Players
Published 2025-02-01“…Dependent samples t-tests compared changes in DJ metrics, while repeated measures analyses of variance compared changes in RJ metrics. …”
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3786
Study on flexural cracking characteristics of polypropylene fiber reinforced concrete beams with BFRP bars
Published 2025-07-01“…When the flexural bearing capacity is 80 %, the average crack spacing is reduced by 6.1 % - 13.4 %. …”
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3787
¿Hambre en México? Una alternativa metodológica para medir seguridad alimentaria
Published 2019-01-01“…Conclusiones: Las políticas públicas deben distinguir niveles de seguridad alimentaria y dar prioridad a políticas económicas y de salud a nivel nacional, sin dejar a un lado la política social con programas de combate a la pobreza alimentaria, que persiste en regiones específicas de México.…”
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3788
The phytohormone abscisic acid enhances remyelination in mouse models of multiple sclerosis
Published 2024-12-01“…In in vitro models, we further demonstrated that ABA treatment elevates lipid droplet formation by enhancing the phagocytic capacity of macrophages. Additionally, in a mouse model of microglial activation, we showed that ABA-treated mice maintain a less inflammatory microglial phenotype.ConclusionOur findings highlight a crucial role for macrophages and microglia in enabling ABA to enhance the remyelination process. …”
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3789
ParSite is a multicolor DNA labeling system that allows for simultaneous imaging of triple genomic loci in living cells.
Published 2025-01-01“…A pair of genomic loci labeled by ParSite could be colocalized with p53-binding protein 1 (53BP1) in response to CRISPR/Cas9-mediated double-strand breaks (DSBs). …”
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3790
Quality of life and psychological and gastrointestinal symptoms after cholecystectomy: a population-based cohort study
Published 2017-04-01“…Cholecystectomy for gallstone colic was associated with nausea in men. There were no associations between quality of life, symptoms of anxiety and depression, constipation, heartburn, or acid regurgitation.…”
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3791
Factors associated with successful treatment outcomes among tuberculosis patients in a district municipality of Vhembe, Limpopo
Published 2025-01-01“…Contributions: This study highlight the need for heightened advocacy for supervised TB treatment and increased effort to combat the death of patients while on TB treatment.…”
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3792
Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins
Published 2025-02-01“…Antivirulence drugs offer a new approach to treating bacterial infections by targeting specific virulence factors without affecting bacterial growth, thus helping to combat infection without exerting selective pressure on bacteria or inducing resistance. …”
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3793
Single cell RNA sequencing reveals human tooth type identity and guides in vitro hiPSC derived odontoblast differentiation (iOB)
Published 2023-07-01“…Further, we elucidate the critical role of FGF signaling in odontoblast maturation and its biomineralization capacity using the de novo designed FGFR1/2c isoform specific minibinder scaffolded as a C6 oligomer that acts as a pathway agonist. …”
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3794
Influencia de las universidades colombianas sobre la percepción de la Responsabilidad Social Empresaria de sus estudiantes
Published 2025-01-01“…Se seleccionó una muestra de 925 estudiantes de carreras de gestión de nueve universidades colombianas, y se midió si eran capaces de reconocer 18 prácticas de Responsabilidad Social Empresaria. …”
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3795
The impact of staple crop price instability and fragmented policy on food security and sustainable development: a case study from Bangladesh
Published 2025-02-01“…Wheat prices were generally more stable compared to rice. Despite increased rice production over the years, significant price instability and seasonal fluctuations continue in production, imports, and pricing. …”
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3796
Exploration of the anti-inflammatory potential of Polygonum bistorta L.: protection against LPS-induced acute lung injury in rats via NF-ĸβ pathway inhibition
Published 2025-02-01“…ELISA testing on BALF found that the plant extract efficiently reinstated superoxide dismutase, total anti-oxidant capacity, malondialdehyde, and total oxidative stress. qRT-PCR indicated a decline in the endotoxin-induced overproduction of pro-inflammatory markers, oxidative stress, transcription factor, and downregulated antioxidant potential in extract-treated groups. …”
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3797
Effect of tree size attributes on fruit production and animal-mediated seed dispersal web in Melia azedarach L. (Chinaberry) in north-west Himalaya, India
Published 2025-01-01“…Our findings indicate that the tree-size attributes like diameter, height, and crown length strongly affected fruit yield capacity in trees of Melia azedarach. Large trees are likely to be reproductively matured and are prioritising resources for reproduction rather than growth. …”
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3798
Equitable transportation and resilience hubs: Analysis of underserved population needs, usage, and travel behaviour
Published 2025-01-01“…To begin addressing these problems and increase community capacity, resilience hubs – physical locations that support residents in emergencies and everyday conditions – have emerged as a possible equitable strategy. …”
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3799
Genome-wide identification and characterization of transcription factors involved in defense responses against Sclerotinia sclerotiorum in Brassica juncea
Published 2025-02-01“…Nevertheless, the availability of immune or highly resistant germplasm and mechanisms to combat S. sclerotiorum, particularly in B. juncea, remains insufficient. …”
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3800
GmERF57 negatively regulates root development and phosphate absorption in soybean
Published 2025-03-01“…Silencing GmERF57 expression promoted root development and enhanced plant Pi uptake; conversely, overexpression of GmERF57 yielded contrasting phenotypes compared to silenced roots. We further uncovered that GmERF57 physically interacts with GmTUB1 (β-tubulin protein) and modulates soybean root architecture and Pi uptake capacity by downregulating GmTUB1 and other Pi starvation response genes. …”
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