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Transcriptome analysis and cytochrome P450 monooxygenase reveal the molecular mechanism of Bisphenol A degradation by Pseudomonas putida strain YC-AE1
Published 2023“…Pseudomonas putida YC‑AE1 was isolated in our previous study and exerted a strong degradation capacity toward BPA at high concentrations; however, the molecular degradation mechanism is still enigmatic. …”
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3864
In vitro propagation of Codonopsis pilosula (Franch.) Nannf. using apical shoot segments and phytochemical assessments of the maternal and regenerated plants
Published 2023“…Furthermore, the tissues (roots and shoots) of maternal and in vitro‑regenerated C. pilosula plants were subjected to Fourier‑transform near‑infrared (FT‑NIR) spectrometry, Gas chromatography‑mass spectrometry (GC–MS), and their total flavonoids, phenolics, and antioxidant capacity were determined and compared. Results Full‑strength Murashige and Skoog (MS) medium augmented with vitamins and benzylaminopurine (1.5 mg·L−1 ) regenerated the highest shoot number (12 ± 0.46) per explant. …”
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3865
Motivation And Employees’ Performance in Local Governments: A Case Study of Kabale Municipal Council, Kabale District
Published 2023“…The study recommends that the government offers support in form of capacity building and staff promotions as a way of realizing quality and good performance in the local governments and the administration of Kabale Municipal Council. …”
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3866
Learners' Perception of English Language Learning in Universal Secondary Schools in Kisoro District.
Published 2023“…Since effective learning takes place through interactive communication between the more knowledgeable person and the learner, there must be a more empowering plan to ensure that teachers and learners have basic capacity to use English as the medium of instruction. …”
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3867
Relato de uma extensão em tempos de isolamento social: Criação de um recurso educacional sobre matemática na pandemia de COVID-19
Published 2025-02-01“…Neste cenário, surgiu o projeto de extensão “A Matemática na Pandemia de COVID-19” da UNIFESP, no qual uma dupla de professores universitários com formação em Física propôs levar informações e conhecimentos matemáticos às pessoas através do Facebook®, com o objetivo de combater a desinformação e subsidiar a população na compreensão de dados divulgados sobre a pandemia. …”
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Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer
Published 2025-02-01“…This study underscores the therapeutic potential of TRII/21R-modified CAR-NK cells as a breakthrough strategy for combating cancer.…”
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3869
Epidemiology and Factors Influencing Davis Cup Retirements Over the Past Twenty Years
Published 2024-11-01“… # Conclusion This study provides valuable insights for coaches, players, support teams, and epidemiologists regarding retirements and their associated risk factors in Davis Cup tournaments. …”
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In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection
Published 2025-03-01“…The rapid development of mRNA drugs highlights the potential of mRNA-encoded ACE2 decoys in emergencies to combat diverse SARS-CoV-2 variants, including future variants.…”
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The dipeptide carnosine alleviates acute pancreatitis in an experimental model
Published 2024-12-01“…Moreover, alterations in oxidative stress biomarkers in the pancreas, including ROS formation, decreased antioxidant capacity, lipid peroxidation, and glutathione depletion, were detected in the AP group (P<0.001). …”
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Transcriptomic, histological and biochemical analyses of Macrobrachium nipponense response to acute heat stress
Published 2025-01-01“…The digestive, metabolic, and antioxidative capacity were enhanced in the gills and hepatopancreas of M. nipponense at 30 °C and 35 °C. …”
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Exploring the Mechanisms of Zhenbao Pills in the Treatment of Stroke through Network Pharmacology Combined with Mendelian Randomization
Published 2025-01-01“…We also used Mendelian randomization (MR) to assess causal relationships between feature genes and stroke incidence, for which colocalization was employed for validation. Furthermore, molecular docking and Gene Expression Omnibus (GEO) datasets were used for preliminary confirmation. …”
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A nucleoside-modified mRNA vaccine prevents enterovirus A71 infection in mouse model
Published 2025-02-01“…Immune sera provided complete protection against lethal EV-A71 challenge, significantly reducing viral load and pathology.DiscussionThis study demonstrates that the mRNA vaccine exhibits significant potential for combating non-enveloped viruses. These findings highlight the promising role of mRNA platforms in advancing vaccine development against non-enveloped viral pathogens, offering new avenues for future research and clinical applications.…”
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Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies.
Published 2025-01-01“…Development of new vaccines and antibodies for emerging viral threats requires substantial resources and time, and traditional development platforms for vaccines and antibodies are often too slow to combat continuously evolving immunological escape variants, reducing their efficacy over time. …”
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Actividad larvicida de especies vegetales de la flora salvadoreña para el control de Aedes aegypti
Published 2020-06-01“… En la lucha por la protección del medio ambiente y la salud de la población, es de vital importancia encontrar formas alternativas de control para el combate de insectos vectores como el Aedes aegypti. …”
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Characterization of subcutaneous and visceral de-differentiated fat cells
Published 2025-03-01“…Objective: The capacity of mature adipocytes to de-differentiate into fibroblast-like cells has been demonstrated in vitro and a few, rather specific in vivo conditions. …”
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Medicalización y cólera en Córdoba a fines del siglo XIX. Las epidemias de 1867-68 y 1886-87
Published 2016-01-01“…De este modo, consideramos que la conformación de ciertas instituciones, como el Consejo de Higiene Provincial y la Asistencia Pública Municipal, determinó el ascenso de la élite médica a ciertos niveles del Estado, lugares desde donde pudieron legitimarse con el desarrollo de estrategias de combate contra el cólera.…”
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Assessment of Land Use and Land Cover Changes in Afi River Forest Reserve Cross River State, Nigeria
Published 2025-02-01“…The observed trends highlight the urgent need for immediate action to combat environmental degradation in the Afi River Forest Reserve. …”
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Changes in the intestinal microbiota induced by the postnatal environment and their association with hypertension
Published 2025-02-01“…Moreover, decreased systolic blood pressure was observed in the SW group compared to the SS group in adulthood. Thus, we could establish a link between microbiota composition and hypertension development, associating it with the loss of the ''low-abundance'' bacterial taxa. …”
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