Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action by Aurangzeb Sana, Aurongzeb Muhammad, Shamim Shahbaz, Rashid Yasmeen, Khan Khalid Mohammed, Aziz Tariq, Alharbi Metab, Alasmari Abdullah F.

“…Normal mode analysis investigations provided additional confirmation regarding the stability of the conformational interactions between the HslV protease and the active compounds. In addition, the predicted absorption, distribution, metabolism, excretion, and toxicity properties of these lead compounds remarkably demonstrated their considerable drug-like and non-toxic qualities. …”
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Anthelmintic activity of 1,10-phenanthroline-5,6-dione-based metallodrugs by Maria E. Cirino, Thainá R. Teixeira, Alessandro M. H. Silva, Ana C. C. Borges, Lucas Fukui-Silva, Luis G. Wagner, Christiane Fernandes, Malachy McCann, André L. S. Santos, Josué de Moraes

“…Given the promising biological properties of phendione and its metal complexes, these findings contribute to the growing body of research seeking to address the urgent need for new anthelmintic therapies.…”
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Dependence on Humidity and Aerosol Composition of the Gas-particle Partitioning of Weakly and Moderately Polar VOCs by Jeonghyeon Ahn, Guiying Rao, Eric P. Vejerano

“…Kp values for both TCE and n-BuOH decreased as RH levels increased; the Kp for both VOCs declined sharply at an RH > 35% onto inorganic aerosol particles, whereas the Kp declined slowly onto organic aerosol particles. …”
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Impact of Biomass Burning on Air Quality in Temuco City, Chile by Felipe Reyes, Sofía Ahumada, Francisca Rojas, Pedro Oyola, Yeanice Vásquez, Claudio Aguilera, Andres Henriquez, Ernesto Gramsch, Choong-Min Kang, Sanna Saarikoski, Kimmo Teinilä, Minna Aurela, Hilkka Timonen

“…Abstract Residential wood burning emits a complex mixture of particulate and gaseous compounds. In this article we show an in-depth chemical characterization of particulate matter evidencing the impact of biomass burning on the urban air quality in Greater Temuco, the capital city of the Araucanía Region, Chile. …”
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Unlocking the potential of hydrogen deuterium exchange via an iterative continuous-flow deuteration process by Kevin Tatoueix, Marco Lepron, Cédric Barboux, Marie-Christine Scherrmann, Grégory Pieters, Sophie Feuillastre

“…This report pinpoints an approach to unlock the potential of HDE using the concept of iterative runs in continuous-flow technology (recirculation process). This closed-loop process grants access now to deuterated compounds with high isotopic purities, labelled at a precise site or perdeuterated on demand, in a fast, productive, and environmentally friendly way.…”
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Manufacture and characterization of lightweight sand-plastic composites made of plastic waste and sand: Effect of sand types by Salih Mekideche, Mansour Rokbi, Zine El Abidine Rahmouni, Resego Phiri, Sanjay Mavinkere Rangappa, Suchart Siengchin

“…Many tests and analysis were carried out in this investigation. First of all, two initial used compounds (waste PP and various silica sand) were analyzed by using ATR-FTIR, XRF, and grain size distribution. …”
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Herbal remedies as a potential alternative therapy for arthritis by Disha Trivedi, Riya Jayapal Roja, Eva Künnemann

“…Additionally, regular movement of the joints is necessary for natural compounds to act in the human body and provide wellness.…”
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Phytocannabinoids: a new frontier in Alzheimer’s disease management by Jagadeesh S. Rao

“…Both phytocannabinoids contribute to physiological and pharmacological effects. …”
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Chemical characterization of fruits of Garcinia brasiliensis Mart. by Caroline Woelffel Silva, Patricia Cristina Gonçalves, Camile Zanichelli Costa, Karla Lírio Soares, Patrícia Berilli Batista, Stephano Marques, Mário Roberto Maróstica Júnior, Stanislau Bogusz Junior, Oscar Núñez, Rodrigo Scherer

“…The proximate composition was carried out according to A.O.A.C. guide, organic acids by HPLC-PDA, minerals by ICP-OES, fatty acids by GC-FID, B-group vitamins, and the phenolic compounds profile by LC-MS/MS. …”
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A CACTA-like transposon in the Anthocyanidin synthase 1 (Ans-1) gene is responsible for apricot fruit colour in the raspberry (Rubus idaeus) cultivar 'Varnes'. by Daniel James Sargent, Matteo Buti, Stefan Martens, Claudio Pugliesi, Kjersti Aaby, Dag Røen, Chandra Bhan Yadav, Felicidad Fernández Fernández, Muath Alsheikh, Jahn Davik, R Jordan Price

“…Using metabolomics, we quantified anthocyanins in red and apricot raspberry fruits and demonstrated that, in contrast to red-fruited raspberries, fruits of the apricot cultivar 'Varnes' contain low concentrations of only a small number of anthocyanin compounds. …”
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Association between Emission Parameters and Material-phase Concentrations of Phthalate Plasticizers and their Alternatives by Chenyang Bi, Clara M. A. Eichler, Chunyi Wang, John C. Little

“…While concerns have been increasing regarding the use of phthalate plasticizers in products and the emission of phthalates has been characterized in previous studies, the emission characteristics of compounds that are now being used as alternatives for phthalates remain poorly understood. …”
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Guiding chili variety selection for Zao chili in Guizhou: Based on a systematic study of sensory, physicochemical, and volatile characteristics by Xueya Wang, Kuan Lu, Wenxin Li, Ju Chen, Yong Yin, Xiaojing Sun, Min Lu, Jianwen He

“…The ZC produced by FQB3 had the highest comprehensive sensory score (89.7), characterized by high total acid and amino acid nitrogen content and low crude fibre content. There were 181 volatile compounds in the ZCs, including 32 common compounds and 79 differential compounds. …”
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Performance Evaluation of Produced Water Quality from a Nearshore Oil Treatment Facility by DBM Nwokoma, KK Dagde

“…Parameters examined were Temperature, pH, Oil and Grease, Total Dissolved Solids TDS, Total Suspended Solids TSS, Biological Oxygen Demand BOD5. The average temperature of the produced water was reduced from 42.0oC to 25.9oC. …”
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Phytomedicine nanoformulations for Parkinson's disease by Chinthu V. Saji, K P Mohanakumar, Rajesh A Shenoi

“…In recent years, attentions of both clinicians and patients have shifted to herbal medicines that are rich source of bioactive compounds with therapeutic potential to target multiple pathways involved in PD pathology. …”
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The Role of Interviewer Observations in Obtaining Representative Data in Repeated Cross-National Studies by Hafsteinn Einarsson, Alexandru Cernat, Natalie Shlomo

“…These issues can be compounded when conducting cross-national surveys that are repeated over time. …”
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Correlation of Vitamin B12 Levels with Clinical and Laboratory Features in Patients of Dengue Fever by Asma Abdul Razzak

“…Thrombocytopenia and platelet dysfunction, which cause severe bleeding in dengue patients and other life-threatening consequences, are symptoms of this virus. Vitamin B12 aids in preventing thrombocytopenia and maintaining a normal level of thrombocytes4 Compounds having vitamin B12 action are generally referred to as cobalamins since vitamin B12 includes the element cobalt.5 It is crucial for the production and maturation of platelets in the bone marrow hence, a deficit might result in thrombocytopenia. …”
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Direct detection and identification of viruses in saliva using a SpecID ionization modified mass spectrometer. by Pierre Alusta, Angel Paredes, Marli Azevedo, Lisa Mullis, Dan Buzatu

“…This paper describes the use of a SpecID Mass Spectrometer that can detect the presence of viral particles in saliva at very low levels (<500 virions/0.5 ml). The main goal of this study was to demonstrate that our previously developed, portable, mass spectrometry based method, SpecID, could also be sued for detecting viruses in saliva, including but not limited to SARS-CoV-2; the SpecID method has the potential to provide a reliable solution that overcomes some of the challenges with molecular testing like PCR.…”
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Laboratory and field assays indicate that a widespread no-see-um, Culicoides furens (Poey) is susceptible to permethrin by Vilma M. Cooper, Eva A. Buckner, Yongxing Jiang, Nathan Burkett-Cadena

“…With adulticides as the primary method of Culicoides control, there is growing concern about insecticide resistance, compounded by the lack of tools to monitor Culicoides susceptibility. …”
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The role of microorganisms and microbial enzymes in commercial fermented mushroom production: a comprehensive review of their action mechanisms, quality attributes and health benef... by Mohamed A. Farag, Nurkhalida Kamal, Hamizah Shahirah Hamezah, Merna Saleh, Jiachao Zhang, Ahmed Mediani, Mostafa H. Baky

“…Several studies have demonstrated that bioactive compounds from mushrooms exert remarkable biological activities, however, they have low oral bioavailability, restricting their therapeutic application. …”
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Synergizing GIS and genetic algorithms to enhance road management and fund allocation with a comprehensive case study approach by Ahmed Gouda Mohamed, Fahad K. Alqahtani, ElHassan Reda Ismail, Mohamed Nabawy

“…Abstract This study identifies a critical knowledge gap, revealing how the deterioration of roads, compounded by extensive usage and additional factors, poses significant risks to the road networks’ functionality. …”
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