Hymecromone Administration in Real Clinical Practice: Results of the Prospective Multicentre Observational Study in the Republic of Kazakhstan by A. V. Nersesov, D. A. Kaybullaeva, V. S. Rakhmetova, I. A. Lozinskaya, A. K. Kurmangalieva, V. S. Ayupova, A. B. Orazbaeva, A. K. Kanabaeva, Yu. O. Shulpekova

“…The study included 2 patient visits and an intermediate telephone contact. A visual analogue scale and RAPID questionnaire were used to characterise biliary pain; severity of associated symptoms, bowel habit and a quality of life according the SF-12 were also assessed. …”
Get full text

EMT-driven plasticity prospectively increases cell–cell variability to promote therapeutic adaptation in breast cancer by Lauriane Muller, Frédérique Fauvet, Christelle Chassot, Francesca Angileri, Angèle Coutant, Cyril Dégletagne, Laurie Tonon, Pierre Saintigny, Alain Puisieux, Anne-Pierre Morel, Maria Ouzounova, Pierre Martinez

Get full text

Health and social care use, costs, and satisfaction among key workers accessing Resilience Hub support during the COVID-19 pandemic by Aleix Rowlandson, Filippo Varese, Linda M. Davies, Paul French, Kate Allsopp, Lesley-Anne Carter, Daniel Hind, Katherine McGuirk, Alan Barrett, Gita Bhutani, Fay Huntley, Joanne Jordan, May Sarsam, Hein Ten Cate, Holly Walker, Ruth Watson, Jack Wilkinson, Jenni Willbourn, Gemma E. Shields

“…Most Hub clients reported Hub contact post referral (219/299, 73.2%), with many accessing mental health support (171/299, 57.2%) or on waitlists (34/299, 11.4%). …”
Get full text

Economic-productive analysis of a mixed cattle-bubaline model mixed model in the Northern region of Corrientes Province in Argentina by Pablo Maldonado-Vargas, Vanesa Guadalupe Mierke, Liliana Laura Pellerano, Guillermo Sebastián Grimaldi, Orlando Alberto Álvarez, Natalia Mercedes Vallejos, Margarita Rosa Itatí Romero, Francisco Daniel Romero, Alexis Sebastián Bandeo, Gonzalo Enrique Tuñón, José Luis Konrad

“… The production of buffaloes has been consistently growing in Argentina, with an increase in the number of animals and spread in 19 of the 23 provinces of the country, with an evident regional grouping. The Northeastern region of Argentina contains the provinces of Corrientes, Formosa, Chaco, Misiones, and Entre Rios, where 88.89% of the buffaloes, with Corrientes having the most significant numbers of animals and farmers. …”
Get full text

CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens by Sara W. Feigelson, Tali Dadosh, Nehora Levi, Anita Sapoznikov, Hadas Weinstein-Marom, Hadas Weinstein-Marom, Dayana Blokon-Kogan, Dayana Blokon-Kogan, Yahel Avraham, Tamar Unger, Gideon Gross, Gideon Gross, Rony Dahan, Ronen Alon

“…For efficient mAb decoration, we have introduced a mAb binding Fc receptor (FcR) scaffold, FcγRIIB1 (CD32B1), which we found to be enriched on B lymphocyte microvilli (MV). This isoform contains an inhibitory ITIM motif within a cytoplasmic tail anchored to the cortical cytoskeleton. …”
Get full text

Refined construction of semi-provincial hydrogeological models using hierarchical modeling: A case study in Western Shandong Province, China by Guangjun Ji, Zizhao Cai, Xiaobo Tan, Tao Wang, Chuanqi Wang, Qiuxiao Xu, Bo Zhou, Yang Cui

“…Study region: Western Shandong Province, China, covering an area of 83,700 km², is a study area that contains various representative hydrogeological conditions. …”
Get full text

A multistage drug delivery approach for colorectal primary tumors and lymph node metastases by Yihang Yuan, Quanjun Lin, Hai-Yi Feng, Yunpeng Zhang, Xing Lai, Mao-Hua Zhu, Jue Wang, Jiangpei Shi, Yanhu Huang, Lele Zhang, Qin Lu, Zeli Yuan, Jonathan F. Lovell, Hong-Zhuan Chen, Peng Sun, Chao Fang

“…The liposomal membrane contains 1,2-dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) (DPPG) and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), two phospholipids sensitive to secreted phospholipase A2 in human colorectal tumors. …”
Get full text

Prediksi Bidang Penelitian dan Rekomendasi Dosen Pembimbing Skripsi Berdasarkan Konten Latar Belakang pada Naskah Proposal Menggunakan Metode Multi-Class Support Vector Machine dan... by Yustinus Radityo Pradana, Ahmad Afif Supianto, Yusi Tyroni Mursityo

“…Abstract In Fakultas Ilmu Komputer Universitas Brawijaya (FILKOM UB), thesis work started by making preproposal which contains the background and thesis  field/topic. In the working of thesis, undergraduate student needs to be accompanied by a supervisor. …”
Get full text

Exploring expressed concerns and uncanny feeling in patients with shortness of breath calling out-of-hours primary care by Michelle Spek, Dorien L. Zwart, Esther de Groot, Michelle R. Timmerman, Maarten van Smeden, Daphne C. A. Erkelens, Anna S. M. Dobbe, Mathé Delissen, Frans H. Rutten, Roderick P. Venekamp

“…Abstract Background Patients contacting out-of-hours primary care (OHS-PC) with shortness of breath (SOB) are often concerned. …”
Get full text

Perancangan User Experiance Website Travel Mabruro Menggunakan Pendekatan Human-Centered Design by Safira Nur Rahmah, Hanifah Muslimah Az- Zahra, Yusi Tyroni Mursityo

“…Namun pandemi COVID-19 membuat Travel Mabruro membutuhkan pelayanan online dalam pengelolaan pendaftaran jamaah dan pengurusan administrasi guna mengurangi kontak fisik yang dilakukan, untuk itu Travel Mabruro memanfaatkan situs web yang telah dimiliki sebelumnya, untuk dilakukan penambahan layanan tersebut. …”
Get full text

Territorios rurales en transformación: desafíos y oportunidades frente al reto de la despoblación by Néstor Vercher

“…Sin embargo, para que estas iniciativas sean viables, es imprescindible contar con infraestructuras y servicios adecuados. …”
Get full text

Territorios rurales en transformación: desafíos y oportunidades frente al reto de la despoblación by Néstor Vercher

“…Sin embargo, para que estas iniciativas sean viables, es imprescindible contar con infraestructuras y servicios adecuados. …”
Get full text

Genetic characteristics and pathogenesis of clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus isolated from poultry in South Korea, 2022–2023 by Ra Mi Cha, Min-Ji Park, Yoon-Gi Baek, Yu-Na Lee, Yunyueng Jang, Yong-Myung Kang, Gyeong-Beom Heo, Se-Hee An, Kwang-Nyeong Lee, Jae-Kyeom Kim, Hye-Ryoung Kim, Youn-Jeong Lee, Eun-Kyoung Lee

“…Ducks inoculated with genotypes 22G1 or 22G7 (A/duck/Korea/H537/2022(H5N1)) showed neurological signs, with 60 %–80 % mortality rate. In the contact groups of ducks, 100 % of transmissibility was observed. …”
Get full text

Determination of the physicochemical and microbiological quality of buffalo milk in the south of lake Maracaibo by Luis Álvarez, Alexis Zambrano, Datty Rosales-Zambrano

“…The purpose of this work is to evaluate the physicochemical and microbiological quality of buffalo milk used in a lactuary in western Venezuela, according to the official regulations in force in the country. It was developed at the Chemical, Industrial and Agricultural Analysis Research Laboratory (LIAQIA), in conjunction with the Venezuelan dairy company CONLAC and the VATCA Laboratory. …”
Get full text

Visual Environment Factors Influencing Staying Behaviors During Cycling on Countryside Greenways by Ting WEN, Yun ZHANG, Ming DU

“…ObjectiveCountryside greenways represent an organic extension of urban green slow-moving traffic systems into suburban areas, addressing urban residents' demands for closer contact with nature and fostering the development of an integrated urban-rural belt. …”
Get full text

Editorial by Jörg Tremmel, Markus Rutsche

“…In his review of Giubilini’s The Ethics of Vaccination, Marius Kunte notes that it contains a “thought-provoking plea” for individual, collective and institutional obligations to reach high vaccination rates. …”
Get full text

Call for Papers: How attractive are political parties and trade unions to young people? by IF and FRFG

“…Its editorial board consists of about 50 internationally renowned experts from ten different countries. The 2/2018 and 1/2019 double edition will have the additional help of Professor Ann-Kristin Kölln, University of Aarhus, who will be serving as guest editor. …”
Get full text

Call for Papers: Constitutions and Intergenerational Justice by IF and FRFG

“…. • Are there any examples of countries where constitutions are regularly reviewed and amended? …”
Get full text

IGJR 1/2020: Housing crisis: How can we improve the situation for young people? by IF and FRFG

“…Its editorial board consists of about 50 internationally renowned experts from ten different countries. IGJR is indexed under Directory of Open Access Journals (DOAJ).   …”
Get full text