Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination sur... by Lihua Huang, Liuliu He, Qingfeng Zeng, Jinjing Huang, Xiaoyan Luo, Qiuming Zhong

“…Hazard ratios (HR) and 95% confidence intervals (CIs) for all-cause and CVD mortality were calculated using weighted Cox proportional hazards and restricted cubic spline models.ResultsAmong the 1,931 participants (mean [SE] age, 73.2 [0.2] years; 61.9% female), over a median follow-up period of 7.6 years, a total of 1,003 deaths were observed, including 412 from CVD. …”
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Symptoms of anxiety, depression, and post-traumatic stress disorder 6 weeks and 6 months after ICU: Six out of 10 survivors affected by E van der Merwe, L Stroud, G Sharp, N van Vuuren, M Mosola, T Fodo, F Paruk

“…The mental component summary score (MCS) of the RAND short form-36 was used to determine the effect of psychological symptoms on health-related quality of life (HRQOL). Results. The median age of the 107 ICU survivors was 42 years, and half of them were admitted for complications of COVID-19. …”
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Interventions for SARS-CoV-2 prevention among Jailed adults: A network-based modeling analysis by Isaac Schneider, Karina Wallrafen-Sam, Shanika Kennedy, Matthew J. Akiyama, Anne C. Spaulding, Samuel M. Jenness

“…A reference scenario and nine intervention scenarios were simulated three hundred times to estimate the median and interquartile range (IQR) of the outcome measures. …”
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Reconocimiento, redistribuición y condición inmigrante: Las luchas de los trabajadores agrícolas de la región de Murcia by Andrés Pedreño Cánovas

“…En un primer momento, el debate apareció como una dicotomía contrapuesta en la que las perspectivas materialistas ponían el acento sobre las desigualdades producidas en el ámbito económico y por tanto en la redistribución como el elemento esencial de la justicia social y, por el contrario, las tendencias postmodernas y multiculturales afirmaban que los cambios culturales en marcha requerían de un énfasis en el reconocimiento. …”
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Epidemiology, clinical spectrum, and outcomes of severe malaria in Eastern Uganda: a prospective study by Cate Namayanja, George Paasi, Jimmy Patrick Alunyo, Denis Amorut, Charles Benard Okalebo, William Okiror, Paul Ongodia, Grace Abongo, Rita Muhindo, Yovani A. M. Lubaale, Peter Olupot-Olupot

“…Results A total of 1,379 participants were recruited. The median age was 4 years (2 months–12 years). Most children 757/1379 (54.9%) were under 5 years, and 825/1379 (59.8%) were males. …”
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How long does it take to start minimal enteral feeding in preterm Neonates admitted to NICUs in Southern Oromia, Ethiopia? by Anteneh Fikrie, Terefu Yambo, Alo Edin, Miesa Gelchu, Dejene Hailu, Mark Spigt

“…Result The overall incidence density of TF initiation was reported as 43.6 per 100 neonate-days. Moreover, the median (IQR) time to initiate TF was found to be 2 (1–4) days. …”
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External validation and revision of the Lafontaine criteria for unstable distal radius fractures: a retrospective study by Pornpanit Dissaneewate, Phatklao Thanavirun, Yanin Tangjaroenpaisan, Kantapon Dissaneewate

“…The criteria were updated using risk factors with stronger associations in the multivariable logistic regression analysis, and the inter-rater reliability of potential predictors was evaluated. Results The median age of the patients was 63 years; 78% were female. …”
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The association between serum fructosamine and random spot urine fructose levels with the severity of non-alcoholic fatty liver disease – an analytical cross-sectional study by H Kamuzinzi, M Kgomo, P Rheeder, N Dada, P Bester

“…There was no significant difference between the groups regarding serum fructosamine, measured as median (interquartile range): mild 257 (241 - 286) μmol/L, moderate 239 (230 - 280) μmol/L and severe 260 (221 - 341) μmol/L, p=0.5; or random spot urine fructose: mild 0.86 (0.51 - 1.30) mmol/L, moderate 0.84 (0.51 - 2.62) mmol/L and severe 0.71 (0.58 - 1.09) mmol/L, p = 0.8. …”
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Barriers to 12-month treatment of common anxiety, mood, and substance use disorders in the World Mental Health (WMH) surveys by Maria Carmen Viana, Alan E. Kazdin, Meredith G. Harris, Dan J. Stein, Daniel V. Vigo, Irving Hwang, Sophie M. Manoukian, Nancy A. Sampson, Jordi Alonso, Laura Helena Andrade, Guilherme Borges, Brendan Bunting, José Miguel Caldas-de-Almeida, Giovanni de Girolamo, Peter de Jonge, Oye Gureje, Josep Maria Haro, Elie G. Karam, Viviane Kovess-Masfety, Jacek Moskalewicz, Fernando Navarro-Mateu, Daisuke Nishi, Marina Piazza, José Posada-Villa, Kate M. Scott, Cristian Vladescu, Bogdan Wojtyniak, Zahari Zarkov, Ronald C. Kessler, Timothy Kessler, World Mental Health Survey collaborators

“…Methods Data on barriers were obtained from face-to-face interviews in 22 community surveys across 19 countries (n = 102,812 respondents aged ≥ 18 years, 57.7% female, median age [interquartile range]: 43 [31–57] years; 68.5% weighted average response rate) in the World Mental Health (WMH) surveys. …”
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Surgical Treatment Patterns, Healthcare Resource Utilization, and Economic Burden in Patients with Tenosynovial Giant Cell Tumor Who Underwent Joint Surgery in the United States by Feng Lin, Winghan J. Kwong, Sherry Shi, Irina Pivneva, Eric Q. Wu, John A. Abraham

“…**Results:** Of 835 eligible TGCT patients, 462 (55%) patients who had ≥1 joint surgery post-index were included. During a median follow-up of 5.7 years, 78% of patients underwent their first joint surgery in year 1 and 41% had ≥1 repeat surgery. …”
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Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults by Wenxin Bian, Raaj K. Biswas, Matthew N. Ahmadi, Yu Sun Bin, Svetlana Postnova, Andrew J. K. Phillips, Nicholas A. Koemel, Jean-Philippe Chaput, Shantha M. W. Rajaratnam, Peter A. Cistulli, Emmanuel Stamatakis

“…We observed a U-shaped association between sleep duration and incident dementia, with only short sleep (< 7 h) being significantly associated with a higher risk of dementia. The median sleep duration for short sleepers (< 7 h) of 6.5 h, compared to the reference point of 7.9 h was associated with HR of 1.19 (95%CI 1.01,1.40) for incident dementia. …”
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Inter-rater reliability and prognostic value of baseline Radiographic Assessment of Lung Edema (RALE) scores in observational cohort studies of inpatients with COVID-19 by Andrew I Kim, William Bain, Alison Morris, Barbara Methe, Bryan J McVerry, Georgios D Kitsios, Daniel Kotok, Janet S Lee, Nameer Al-Yousif, Christine E Girard, Jana J Jacobs, Konstantin Golubykh, Hafiz Qurashi, Michael Lu, Saketram Komanduri, Anatoliy Korzhuk, Halimat O Lawal, Nicholas Abourizk, Caitlin Schaefer, Kevin J Mitchell, Catherine M Dietz, Ellen K Hughes, Clara S Brandt, Georgia M Fitzgerald, Robin Joyce, Asmaa S Chaudhry, Jose D Rivera, Shruti Shettigar, Allen Lavina, Samantha R Gillenwater, Anas Hadeh, Faraaz A Shah, Matthew Bittner, Niall Prendergast, John Evankovich, Navitha Ramesh, Cathy Kessinger

“…In the discovery cohort, the required level of respiratory support at the time of CXR acquisition (supplemental oxygen or non-invasive ventilation (n=178); invasive-mechanical ventilation (n=234), extracorporeal membrane oxygenation (n=13)) was significantly associated with RALE scores (median (IQR): 20.0 (14.1–26.7), 26.0 (20.5–34.0) and 44.5 (34.5–48.0), respectively, p&lt;0.0001). …”
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Noninvasive diagnostic methods of liver fibrosis in patients with primary biliary cirrhosis and primary sclerosing cholangitis: role of indirect serological markers by A. F. Sheptulina, Ye. N. Shirokova, V. T. Ivashkin

“…Results. In PBC group (median age Me [interquartile range] was 54 years [49-62]) 50,5% (n=48) of patients had significant liver fibrosis (F≥2) and 21,1% (n=20) - liver cirrhosis (F4). …”
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Fatores associados às mudanças percebidas na atividade física e comportamento sedentário na comunidade universitária brasileira durante a pandemia da covid-19 by Marcos Cezar Pitombo da Silva Junior, Enaiane Cristina Menezes, Sand Araújo Tenório, Sueyla Ferreira da Silva dos Santos, Thiago Ferreira de Sousa, Luiz Rodrigo Augustemak de Lima

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Baseline atherogenic index of plasma and its trajectory predict onset of type 2 diabetes in a health screened adult population: a large longitudinal study by Yongbing Sun, Xinbei Lin, Zhi Zou, Caiwen Zhao, Ao Liu, Jing Zhou, Zhonglin Li, Xiaoling Wu, Shewei Dou, Jiadong Zhu, Tao Li, Xue Lv, Yong Wang, Yongli Li

“…Methods This longitudinal study included data from 42,850 participants who underwent health check-ups at Henan Provincial People’s Hospital between January 2018 and August 2024. …”
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Treatment Patterns of Long-Acting Somatostatin Analogs for Neuroendocrine Tumors by Callisia N. Clarke, Paul Cockrum, Thomas J.R. Beveridge, Michelle Jerry, Donna McMorrow, Anh Thu Tran, Alexandria T. Phan

“…Compared with octreotide LAR patients, treatment duration was longer for lanreotide patients (median, 41.3 vs 26.8 months; log-rank _p_=.004). Fewer lanreotide patients received rescue treatment with short-acting octreotide (7.9% vs 14.4%; _p_=.011), and a first (6.2% vs 27.3%) and second dose escalation (0.8% vs 5.2%; both _p_<.05). …”
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Clinical Characteristics of 31 Patients with Chest Pain Variant Asthma by Mao W, Gao Y, Sun W, Li J, Wang J, Wang Z, Zhang L, Huang K

“…Main features of chest pain manifested as dull pain and mild pain with unfixed location, and several patients were presented with distending pain, pinprick pain, chest pain related to breathing, chest pain position-related and chest pain like angina pectoris. The median duration of their chest pain was four months, and 77.4% of the patients did not find any trigger. …”
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Long-term safety of tofacitinib up to 9.5 years: a comprehensive integrated analysis of the rheumatoid arthritis clinical development programme by Peter Nash, Yoshiya Tanaka, Kevin L Winthrop, Eun Bong Lee, Xavier Mariette, Jeffrey R Curtis, Kenneth Kwok, Connie Chen, Pinaki Biswas, Lisy Wang, Christina Charles-Schoeman, Ann Madsen, Stanley B Cohen, Andrea Shapiro, Jürgen Wollenhaupt

“…Incidence rates (IRs; patients with events/100 patient-years [PY]; 95% CIs) of first-time occurrences were obtained for adverse events (AEs) of interest.Results 7061 patients received tofacitinib (total exposure: 22 875 PY; median [range] exposure: 3.1 [0 to 9.6] years). IRs (95% CI) for serious AEs, serious infections, herpes zoster (all), opportunistic infections (excluding tuberculosis [TB]) and TB were 9.0 (8.6 to 9.4), 2.5 (2.3 to 2.7), 3.6 (3.4 to 3.9), 0.4 (0.3 to 0.5) and 0.2 (0.1 to 0.2), respectively. …”
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Effectiveness and safety of PD-1/L1 inhibitors as first-line therapy for patients with advanced or metastatic urothelial carcinoma who are ineligible for platinum-based chemotherap... by Weiming Liang, Weiming Liang, Zhijing Wang, Zhilong Huang, Yanping Huang, Chunyan Li, Yiwen Liang, Miaoyan Huang, Duo Zhang, Chenchen Li

“…The CR, PR, SD, PD, ORR, DCR, and grade ≥ 3 trAEs rate were 0.06 [95% confidence interval (CI), 0.04 to 0.07], 0.22 (95% CI, 0.16 to 0.30), 0.27 (95% CI, 0.23 to 0.31), 0.31 (95% CI, 0.20 to 0.44), 0.28 (95% CI, 0.21 to 0.37), 0.57 (95% CI, 0.47 to 0.67) and 0.26 (95% CI, 0.14 to 0.40), respectively. The median PFS and OS were 4.5 months and 13.7 months, respectively. …”
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Epidemiological Changes in Hospitalized Bronchiolitis in Children Under 2 Years of Age in Hangzhou Before and After COVID-19 Restriction Easing by Xu X, Chen X, He J, Su L, Tong X, Sun Y, Huang S, Bai G, Chen Z

“…It also investigated seasonal variations in the incidence of bronchiolitis and pathogen distribution across different years.Results: This study included a total of 697 children with bronchiolitis, with a median age of 7.5 (4.2– 12.0) months. Of these, 68.9% were boys and 31.1% were girls. …”
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