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Spatial and seasonal distribution of selected nitrogen cycle genes in deep waters of the Baltic Proper
Published 2025-02-01“…At all sites, genes encoding nitrogen reduction enzymes were most abundant, while the presence of NOS encoding genes was found in Bacteroidetes and Proteobacteria phyla within all sites. …”
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Subgenome asymmetry of gibberellins-related genes plays important roles in regulating rapid growth of bamboos
Published 2025-01-01“…Our results showed that gibberellin A1 was important for the rapid shoot growth of the world's largest bamboo, Dendrocalamus sinicus, and indicated that two gibberellins (GAs)-related genes, KAO and SLRL1, were key to the rapid shoot growth and culm size in woody bamboos. …”
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East Asian Gene flow bridged by northern coastal populations over past 6000 years
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Overexpression of NtCET4 gene in tobacco promoted vegetative bud activity and delayed flowering
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Inflammatory Gene Signature Identified by Machine Algorithms Reveals Novel Biomarkers of Coronary Artery Disease
Published 2025-02-01“…The intersection of DEGs with inflammation-related genes was used to identify the differentially expressed inflammation-related genes (DIRGs). …”
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Analysis of expression and transport activity of sugar transporter gene HpSWEET7 from red pitaya
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Inactivation of the CMAH gene and deficiency of Neu5Gc play a role in human brain evolution
Published 2025-02-01“…These missing genes might be the key to the evolution of humans’ unique cognitive skills. …”
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Population features of prevalence and clinical-diagnostic role of NOD2 gene polymorphisms associated with Crohn’s disease
Published 2018-08-01“…Key points. It is established that there are significant differences in prevalence and clinical manifestations of R702W, G908R and 3020insC polymorphisms of NOD2 gene associated to CD in different countries, as well as in different regions of the same country and in representatives of different ethnic groups enhabiting different regions. …”
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Exploring MAP3K genes in gastric cancer: biomarkers, tumor microenvironment dynamics, and chemotherapy resistance
Published 2025-02-01“…Methylation profiling further supported the idea that promoter hypomethylation of MAP3K1, MAP3K4, MAP3K7, MAP3K8, MAP3K9, and MAP3K10 genes was associated with their up-regulation. Single-cell functional analysis elucidated the involvement of MAP3K genes in shaping the tumor microenvironment. miRNA-mRNA network analysis revealed intricate regulatory mechanisms, with hsa-mir-200b-3p emerging as a key regulator. …”
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To construct and validate a risk score model of angiogenesis-related genes to predict the prognosis of hepatocellular carcinoma
Published 2025-02-01“…On the single-cell level, it was confirmed that the key genes (AEBP1, ATP2A3, PLAT, and PNMA1) expressed differently between liver cancer and adjacent tissue cell groups. …”
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Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy
Published 2025-02-01“…Thus, this study was conducted to explore the complement system-related key biomarkers for patients with DN. Methods DN microarray datasets were downloaded from the GEO database, followed by differentially expressed genes (DEGs) screening. …”
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Evaluation of the relatedness between the biofilm-associated genes and antimicrobial resistance among Acinetobacter baumannii isolates in the southwest Iran
Published 2025-02-01“…Biofilm production is recognized as a key mechanism contributing to this resistance. This study aims to explore the relationship between biofilm production, the presence of biofilm-associated genes, and antibiotic resistance patterns in A. baumannii isolates obtained from ICU patients. …”
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The Role of Phosphatidylethanolamine-N-methyltransferase (PEMT) Gene rs12449964 Polymorphism in the Development of Acute Pancreatitis and its Complications
Published 2019-12-01“…Along with its function in the synthesis of phosphatidylcholine, the methylation of phosphatidylethanolamine promotes the turnover of S-adenosylmethionine for the synthesis of cysteine and glutathione through transulphurisation. PEMT is a gene encoding the phosphatidylethanolamine-N-methyltransferase enzyme.Aim. …”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease
Published 2025-02-01“…However, the cellular and molecular links between ferroptosis, immune inflammation, and the brain-peripheral blood axis in Alzheimer’s disease (AD) remain unclear.Methods: We integrated bulk RNA-seq data from AD brain tissue and peripheral blood and refined the screening of AD candidate genes through differential gene expression analysis, weighted gene co-expression network analysis (WGCNA), and other approaches. …”
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