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Diversity of beetles (Arthropoda, Insecta, Coleoptera) associated with coniferous forests in Honduras
Published 2025-02-01Get full text
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Spireoside Controls Blast Disease by Disrupting Membrane Integrity of Magnaporthe oryzae
Published 2025-01-01Get full text
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CHOLINE TRANSPORTER-RELATED 4 (CTR4) Is Involved in Drought and Saline Tolerance in Rice
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Methodical approaches in experimental modelling of non-alcoholic fatty liver disease
Published 2015-09-01“…In the first the liver of laboratory animals is the main pathogenic target, metabolic disorders develop insignificantly (lines of animals with of Acetyl-CoA oxidase gene deletion, knockoutmice for methionine-adenosyl transferases-1А gene and animals with deleted specific hepatic phosphatase and tensin homologue gene). …”
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A mechanism-informed deep neural network enables prioritization of regulators that drive cell state transitions
Published 2025-02-01“…Abstract Cells are regulated at multiple levels, from regulations of individual genes to interactions across multiple genes. Some recent neural network models can connect molecular changes to cellular phenotypes, but their design lacks modeling of regulatory mechanisms, limiting the decoding of regulations behind key cellular events, such as cell state transitions. …”
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Alternative splicing expands the antiviral IFITM repertoire in Chinese rufous horseshoe bats.
Published 2024-12-01“…The human interferon-induced transmembrane protein (IFITM) family consists of three antiviral IFITM genes that arose by gene duplication. These genes restrict virus entry and are key players in antiviral interferon responses. …”
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Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro
Published 2025-02-01“…Except G2576T mutations in 23S rRNA gene, the distribution of other mutations (A2451T, T2504A, C2404T, T2500A, G2447T) exhibited obvious strain heterogeneity. …”
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A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer
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A new signature associated with anoikis predicts the outcome and immune infiltration in nasopharyngeal carcinoma
Published 2025-02-01“…Key gene expression levels were validated through real-time PCR and immunohistochemical staining. …”
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Exploring biomarkers and molecular mechanisms of Type 2 diabetes mellitus promotes colorectal cancer progression based on transcriptomics
Published 2025-02-01“…The key biological processes were screened by gene ontology and gene set enrichment analysis. …”
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Single-cell landscape of dynamic changes in CD8+ T cells, CD4+ T cells and exhausted T cells in hepatocellular carcinoma
Published 2025-02-01“…Differential expression of seven genes in CD8+ T cells, CD4+ T cells and exhausted T cells were key targets for improving immunotherapy response in HCC.…”
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Blood molecular subtypes to guide precision treatment strategies in systemic juvenile idiopathic arthritis
Published 2025-02-01“…GSK3B and p38 MAPK inhibitors showed a significant counteracting effect on the perturbed gene expression of sJIA. Conclusions Neutrophil activation was the key feature in active sJIA. …”
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GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease
Published 2025-02-01“…Subsequently, the expression of hub genes was validated using additional TBI- and PD-related GEO datasets and the Comparative Toxicogenomics Database (CTD). …”
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Decoding the specific minty-like aroma of ‘Rucheng baimaocha’ (camellia pubescens) black tea
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Moss-pathogen interactions: a review of the current status and future opportunities
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