Transitioning from wet lab to artificial intelligence: a systematic review of AI predictors in CRISPR by Ahtisham Fazeel Abbasi, Muhammad Nabeel Asim, Andreas Dengel

“…Abstract The revolutionary CRISPR-Cas9 system leverages a programmable guide RNA (gRNA) and Cas9 proteins to precisely cleave problematic regions within DNA sequences. This groundbreaking technology holds immense potential for the development of targeted therapies for a wide range of diseases, including cancers, genetic disorders, and hereditary diseases. …”
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Spatial heterogeneity in deployment and upscaling of wind power in Swedish municipalities by Yodefia Rahmad, Fredrik Hedenus, Jessica Jewell, Vadim Vinichenko

“…One approach is to examine historical deployment to identify factors shaping its distribution within a country. Current literature presents inconsistent results and lacks theoretically grounded approaches. …”
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Changes in faecal haemoglobin values over sequential rounds of faecal immunochemical tests (FIT) in a surveillance population by Amanda J Cross, Kate Wooldrage, Gemma Mortell, Gwen A Murphy

“…We investigated whether changes in FIT values over multiple rounds were associated with advanced colorectal neoplasia (ACN) detection.Methods A cohort of men and women aged 60–72 years deemed intermediate risk by the 2002 UK adenoma surveillance guidelines and scheduled for three yearly colonoscopies were recruited (January 2012–December 2013) within the English Bowel Cancer Screening Programme and offered a quantitative FIT at 1, 2 and 3 years post-baseline colonoscopy for a prospective analysis within a diagnostic accuracy study. …”
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A wicked problem: Systemic issues surrounding Canadian equestrian dressage and dressage horse welfare by Megan Ross, Kathryn Proudfoot, Katrina Merkies, Charlotte Lundgren, Caroline Ritter

“…The objectives of this study were to: (1) explore the cultural context of the Canadian dressage industry, including how horse well-being is integrated within the culture; and (2) investigate coaches’ and riders’ perceptions and experiences with the use of horses for dressage. …”
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THE DEVELOPMENT OF A MOBILE APPLICATION ISMIND FOR FORMATIVE STUDENTS’ ASSESSMENT by Aslina Saad, Fatin Naiemah Khairulanuar, Bahbibi Rahmatullah

“…The proposed methodology consists of the details of phases, various activities within each phase, techniques, models, and tools for each activity as well as deliverables of each phase offer a helpful guideline for anyone interested in developing a similar application. …”
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Implementation of a Targeted Technologic Screening Tool to Increase Pneumococcal Vaccine Uptake in Health-System Retail Pharmacies: A Quality Improvement Initiative by Annika Skogg, Alicia Zagel, R. May O'Donnell, Ann Philbrick, Mary Nelson, Allyson Schlichte, Kassie Klasen

“…Methods: A PDSA cycle was employed to activate alerts within 24 retail pharmacies for patients indicated to be eligible for PCV20 vaccination. …”
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Effectiveness of a Protective Barrier for Aerosol Transmission Control during Oxygen Therapy with Different Devices by Hsiu-Mei Chang, Ben-Ran Fu, Hao-Wei Yu, Fu-Tsai Chung, Chen-June Seak, Ying-Chun Chen, Shih-Cheng Hu

“…Experiments using solely protective barrier (Case C) showed higher improvements in aerosol leakage than those using only the air extraction system (Case B); however, aerosol accumulation within the protective barrier remains an issue. In cases (Case D) using both the air extraction system and a protective barrier, the improvements were the highest, with some values even exceeding 99%; additionally, the aerosol concentration within the protective barrier was reduced. …”
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Estimation of population structure in emmer wheat germplasm conserved in the National Genebank of India by Jatin Tanwar, Sandhya Tyagi, Shivani Sharma, Preeti Jakhar, Gaurav Kumar, Sherry R. Jacob, Amit Kumar Singh, Shailendra K. Jha, Jyoti Kumari

“…Indigenous and exotic collections were categorized into distinct subclusters within the same cluster with some overlapping suggesting limited genomic differentiation between these collections. …”
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Enhanced brightness and photostability of dye-sensitized Nd-doped rare earth nanocomposite for in vivo NIR-IIb vascular and orthotopic tumor imaging by Syue-Liang Lin, Shih-Po Su, Yuan-Zhen Yang, Cheng-Yu Chiang, Hsin-Yu Chi, Cheng Allen Chang, Tse-Ying Liu, Huihua Kenny Chiang

“…Abstract Rare-earth doped nanoparticles (RENPs) have shown promise in biomedical imaging, particularly within the NIR-IIb region, due to their deep tissue penetration and minimal light scattering. …”
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Analysis of significantly associated regions and candidate genes for dwarf stem trait in Brassica napus based on BSA-sequencing by ZHAO Weiguo, TA Na, WANG Hao, YANG Zelin

“…Five candidate genes within the significantly associated regions were identified and involved in the regulation of plant auxin synthesis and gibberellin signal transduction.…”
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Pre-injection of exosomes can significantly suppress ovarian cancer growth by activating the immune system in mice by Yuanyuan Wang, Changyi Zhang, Huimin Zeng, Liangliang Wang, Zanhong Wang, Zhiqiang Han

“…Furthermore, we found a substantial increase in the proportion of CD3 + T cells, particularly CD8 + T cells, within the omental tissue where exosomes homed. This increase was accompanied by a significant enhancement in granzyme B levels within CD8 + T cells. …”
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Influence of day and night temperature and carbon dioxide concentration on growth, yield, and quality of green butterhead and red oakleaf lettuce. by Sean T Tarr, Roberto G Lopez

“…Production of lettuce (Lactuca sativa) within vertical farms is an expanding segment of controlled environment agriculture-precise manipulation of environmental parameters including mean daily temperature (MDT) and carbon dioxide (CO2) concentration enables year-round production, alongside color, yield, and crop size regulation. …”
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Mortality and readmission following hip fracture surgery: a retrospective study comparing conventional and fast-track care by Kristin Haugan, Lars G Johnsen, Trude Basso, Olav A Foss

“…Objective To compare the efficacies of two pathways—conventional and fast-track care—in patients with hip fracture.Design Retrospective single-centre study.Setting University hospital in middle Norway.Participants 1820 patients aged ≥65 years with hip fracture (intracapsular, intertrochanteric or subtrochanteric).Interventions 788 patients were treated according to conventional care from April 2008 to September 2011, and 1032 patients were treated according to fast-track care from October 2011 to December 2013.Primary and secondary outcome Primary: mortality and readmission to hospital, within 365 days follow-up. Secondary: length of stay.Results We found no statistically significant differences in mortality and readmission rate between patients in the fast-track and conventional care models within 365 days after the initial hospital admission. …”
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Frailty in older adults admitted to hospital: outcomes from the Western Sydney Clinical Frailty Registry by Julee McDonagh, Richard I Lindley, Karen Byth, Reejamol John, Caleb Ferguson

“…Abstract Objectives To examine baseline frailty and its association with rehospitalisation and mortality within 12 months among older adults enrolled in the Western Sydney Clinical Frailty Registry. …”
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Stigma associated with mental illness: perspectives of judges and attorneys in Lebanon — a cross-sectional study by Rayan Mroué, Michele Cherro, Ghida Kassir, Elias Ghossoub, Nadia Dandan

“…Conclusions The findings imply that enhancing mental health education and awareness within the legal profession could be a key strategy to reduce stigma and improve the overall treatment of individuals with mental health issues within the criminal justice system in Lebanon.…”
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Assessment of Knowledge Gaps in Cervical Cancer Screening and HPV Vaccination Among Chinese Women: A Comprehensive Population-Based Study by Huang X, Ruan G, Sun P

“…Factors associated with lower CCS knowledge included low monthly household income, lack of rural cooperative medical insurance, low literacy, not having received CCS within the past 3 years, unmarried status, and childbirth history. …”
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Investigating the role of endocytosis in the uptake of photoassimilates in Gracilariopsis lemaneiformis (Rhodophyta) by Haihong Chen, Ziyan Shi, Hongxin Ji, Shengqi Ye, Xiaoqian Zhou, Zhijie dan, Xin Shen

“…Further inhibition of endocytic activity in G. lemaneiformis using EIPA resulted in a significant reduction in the content of floridean starch within NEC, whereas the decrease in floridean starch content in EC was not statistically significant. …”
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Short-term endoscopic alterations of early gastric cancer after successful eradication of Helicobacter pylori by Xiaohan Yan, Jingze Li, Zehua Zhang, Bensong Duan, Meidong Xu, Qinwei Xu

“…However, our study aimed to investigate the endoscopic alterations of EGC within 3 months after eradication, which has not been reported clearly yet. …”
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Heterogeneity analysis provides evidence for a genetically homogeneous subtype of bipolar-disorder. by Caroline C McGrouther, Aaditya V Rangan, Arianna Di Florio, Jeremy A Elman, Nicholas J Schork, John Kelsoe, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium

“…<h4>Results</h4>In this paper, we leverage recent advances in heterogeneity analysis to look for genetically-driven subgroups (i.e., biclusters) within the broad phenotype of Bipolar Disorder. We first apply this covariate-corrected biclustering algorithm to a cohort of 2524 BD cases and 4106 controls from the Bipolar Disease Research Network (BDRN) within the Psychiatric Genomics Consortium (PGC). …”
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A comparative study of traditional high-fidelity (manikin-based) simulation and virtual high-fidelity simulations concerning their effectiveness and perception by Izabela Sałacińska, Patrycja Trojnar, Krisztina Éles Gebriné, Viktória Törő, Viktória Törő, Attila Sárváry, Paweł Więch

“…Furthermore, there were no notable differences between virtual and traditional simulations regarding specific aspects such as satisfaction with learning, self-confidence in learning, and expectations. However, within the virtual simulation group, females rated active learning significantly higher. …”
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