Wake-up call for recovery: a paradigm shift to address the deep crisis in Israel’s public mental health services in the shadow of October 7, 2023 by Amir Krivoy, Gadi Rosenthal

“…This transformation aims to create a holistic, efficient, and patient-centered mental health system, better equipped to handle future challenges and reduce the societal and economic burdens of mental illness in Israel.…”
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Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases by Wei Wei, Michael Hurwitz, Sabina Signoretti, Lucia Jilaveanu, Toni K Choueiri, David L Rimm, Adebowale Adeniran, Sandra Martínez, Harriet M Kluger, David A Schoenfeld, Myrto Moutafi, Dijana Djureinovic, Ross D Merkin, David A Braun, Fabio Parisi

“…Our findings may have important implications for designing future biomarker and treatment studies and may aid in development of brain metastases-specific therapies.…”
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fNIRS neurofeedback facilitates emotion regulation: Exploring individual differences over the ventrolateral prefrontal cortex by Yiwei Li, Sijin Li, Hua Li, Yuyao Tang, Dandan Zhang

“…This research underscores the potential of personalized NF approaches, offering new avenues for tailored therapeutic interventions in the future.…”
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How to teach the anatomy of the inguinal canal? A multimodal approach by Shina Yeo Qing Chun, Nathaniel Dexter Salim, Lai YuFu Jarrell, Joshua Koh Zhi Yuan, Eng-Tat Ang, Davide Lomanto

“…Additionally, results from group model creation could be affected by the dynamics amongst members. Future work should aim to address these issues.…”
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Improved population coverage of the human papillomavirus vaccine after implementation of a school-based vaccination programme: the Singapore experience by Karuppiah Vijayalakshmi, Anne Hui Yi Goei

“…This model can be applied to future school health programmes.…”
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Challenges and barriers to physician decision-making for prescribing and deprescribing among patients with multimorbidity in eastern China’s primary care settings: a qualitative st... by Ming Yan, Zhijie Xu, Andrew Farmer, Yu Xia, Mi Yao, Lingyan Wu, Xinmei Zhou, Liyan Han

“…The challenges were further compounded by multiple barriers, including clinical inertia among physicians, patient resistance to medication changes, inadequate decision support and training, and time constraints in clinical consultation.Conclusions The complexity of prescribing and deprescribing decisions faced by PCPs in treating patients with multimorbidity in China is influenced by interconnected factors related to physicians, patients, technology and working environment. Future research could develop and evaluate implementation strategies to address specific challenges and barriers to allow PCPs to make effective medication decisions for patients with multimorbidity.…”
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Challenges for funders in monitoring compliance with policies on clinical trials registration and reporting: analysis of funding and registry data in the UK by Rachel L Knowles, Frances Rawle, Kam Pou Ha, Julia Mueller, Rosa Parker

“…Reporting of the main findings was achieved for most trials within 24 months of completion; however, the number of unreported trials remains a concern and should be a focus for future funder policy initiatives. Identifying trials from grant management and grant monitoring systems was challenging therefore funders should ensure investigators reliably provide trial registries with information and regularly update entries with details of trial publications and protocols.…”
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Hybrid intelligence framework for optimizing shear capacity of lightweight FRP-reinforced concrete beams by Iman Faridmehr, Moncef L. Nehdi, Mohammad Ali Sahraei, Kiyanets Aleksandr Valerievich, Chiara Bedon

“…Incorporating artificial intelligence, sophisticated optimization methodologies, and thorough statistical evaluations establishes a holistic approach for the structural examination of FRP-RC beams, providing improved precision and valuable viewpoints for the refinement of future designs.…”
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Comparative Analysis of Biomarkers in Type 2 Diabetes Patients With and Without Comorbidities: Insights Into the Role of Hypertension and Cardiovascular Disease by Symeon Savvopoulos, Haralampos Hatzikirou, Herbert F Jelinek

“…Mitochondrial oxidative stress indicators, coagulation, and inflammatory markers help assess diabetes disease development and provide appropriate medications. Future studies will examine longitudinal biomarker evolution.…”
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Microvascular dysfunction in a murine model of Alzheimer’s disease using intravital microscopy by Danielle Sidsworth, Noah Tregobov, Noah Tregobov, Colin Jamieson, Jennifer Reutens-Hernandez, Joshua Yoon, Geoffrey W. Payne, Geoffrey W. Payne, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers

“…These findings suggest reduced vascular responsiveness may contribute to the systemic vascular deficits previously observed in AD models. Future research using diverse models and broader variables could further elucidate peripheral vascular dysfunction’s role in AD pathogenesis, including its impact on motor symptoms and disease progression. …”
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Efforts to strengthen anatomic pathology diagnostic services for cancer in sub-Saharan Africa: a scoping review protocol by Katherine Van Loon, Elia John Mmbaga, Marcia Edelweiss, Dianna L. Ng, Asteria Herman Kimambo, Edda Vuhahula, Beatrice Paul Mushi, Omolade Adegoke, Johanna Goldberg, Pendo M. Ibrahim, Zainab Illonga, Julia Jackman, Luisa Jamisse

“…The information gathered will be used to inform the design of future pathology capacity-building interventions. …”
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USING DIGITAL BUSINESS SIMULATORS IN ECONOMIC AND MANAGERIAL DEVELOPMENT OF MASTER’S IN INFORMATION TECHNOLOGIES by Dmytro S. Antoniuk, Oleg M. Spirin, Tetiana A. Vakaliuk

“…The concepts are crucial for future professionals working in IT, interacting in teams, and developing in people- and task-management areas. …”
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Long-chain chlorinated paraffins (LCCPs) exposure induces apoptosis in primary chicken embryo hepatocytes through oxidative stress by Haochu Deng, Yezi Taishi, Guoxia Wang, Yuebing Kong, Ruoting Zhang, Xin Zheng

“…In conclusion, the current work shows that LCCPs have multiple toxic effects on primary chicken embryo hepatocytes, and lays a theoretical foundation for future research on the harmful effects of LCCPs in the poultry industry.…”
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Ethnopharmocology, phytochemistry and pharmacology of the genus Orthosiphon: A review by Rui Wang, Ling Qiu, Qing-wen Zhang, Ligen Lin

“…Don) Benth, which might be attributed to the ethnopharmacological background, geographical constraints, and the distribution of these species. In the future, more investigations on other species of the genus Orthosiphon are needed. …”
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Psychosocial distress, perceived need and utilization of psycho- social support services in patients in the early phase after the first cancer diagnosis by Hannah Zingler, Diana Steinmann, Jochen Ernst, Ute Goerling, Myriel Hermann, Beate Hornemann, Anja Mehnert-Theuerkauf, Tanja Zimmermann

“…These should be investigated in more detail in future studies.…”
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Have crops already reached peak suitability: assessing global climatic suitability decreases for crop cultivation by Vhiny-Guilley Mombo, Mathilde Duvallet, Michiel Schaeffer, Florent Baarsch

“…To gain more precise insights in how future climate change might lead to redistributing productive crop areas, we developed a new method to assess climatic crop suitability, which combines temperature and precipitation suitability through water balance calculations. …”
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A Comparison of Penguin Swarm Optimization Algorithms for Enhancing Network Throughput by Talha Akhtar, Najmi Ghani Haider, Nadeem Kafi Khan, Rashid Uddin

“…With its ability to deliver computing and storage resources at the network's edge, close to device terminals and users, edge computing is an evolving distributed computing approach well-suited for facilitating extensive management of smart devices in the future smart grid. Inspired by the penguin behavior, the Penguin Colony Optimization algorithm (PeCO) is a new meta-heuristic technique used in this study to solve the network load balancing issues. …”
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Advancing treatment choices: CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer by Paola Zagami, Angela Esposito, Beatrice Taurelli Salimbeni, Pier Paolo Maria Berton Giachetti, Roberta Scafetta, Matteo Lambertini, Massimo Di Maio, Giuseppe Curigliano, Carmen Criscitiello, Saverio Cinieri

“…This study explores oncologists' experiences and future perspectives on CDK4/6 inhibitor switching following this new approval. …”
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Experimental trichuriasis: Changes in the immune response and bacterial translocation during acute phase development illustrated with 3D model animation. by Dayane Alvarinho de Oliveira, Renato Oliveira, Brunna Vianna Braga, Lorian Cobra Straker, Luciana Silva Rodrigues, Lilian Lacerda Bueno, Ricardo Toshio Fujiwara, Eduardo José Lopes-Torres

“…This study provides significant insights into the immunological and pathological mechanisms of trichuriasis progression, highlighting the complex interplay among host immune responses, the gut microbiome, and parasite survival strategies, all of which are crucial aspects for future therapeutic development.…”
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Association of arterial stiffness and eye disease: a systematic review and meta-analysis by Robert Scragg, Angela L Beros, John D Sluyter

“…The 19 cohort studies identified (five for AMD, three for glaucoma, one for RVO and 10 for retinopathy) indicated overall that increased arterial stiffness was associated with the future development of eye disease.Conclusions Higher arterial stiffness is associated with AMD, glaucoma, RVO and retinopathyPROSPERO registration number CRD42019129563.…”
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