Structural bioinformatics for rational drug design by Soroush Mozaffari, Agnethe Moen, Che Yee Ng, Gerry A.F. Nicolaes, Kanin Wichapong

“…Artificial intelligence models, alongside traditional physics-based simulations, now play an important role in predicting key properties such as binding affinity and toxicity, contributing to more informed decision-making, particularly early in the drug discovery process. …”
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Artificially intelligent detection of retinal pigment sign using P3S-Net for retinitis pigmentosa analysis by Syed Muhammad Ali Imran, Abida Hussain, Nema Salem, Muhammad Arsalan

“…Moreover, these large-kernel receptive fields yield improved segmentation results with early, intermediate, and late feature information fusion. P3S-Net has an order of magnitude less trainable parameters of 155k in certain scenarios and is smaller than current medical image segmentation techniques. …”
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What impact has the NIHR Academic Clinical Fellowship (ACF) scheme had on clinical academic careers in England over the last 10 years? A retrospective study by James Neilson, David Jones, Sally Clough, James Fenton, Helen Harris-Joseph, Leesa Rayton, Caroline Magee, Lisa Ann Cotterill

“…This was performed using mixed methods including routine data collections of career destination, analysis of application rates to doctoral level fellowships and supplemented by survey information that captured the perceived benefits and challenges from previous ACFs and their current career activities.Participants 1239 NIHR ACFs who completed or left their posts between 2006 and March 2015.Results ACFs are perceived by the candidate population as attractive posts, with high numbers of applications leading to high fill rates. …”
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A Giant Parasitic Leiomyoma with Blood Supply from Omental Branches: A Case Report by Mustafa Ulubay, Fahri Burçin Fıratlıgil, Uğur Keskin, Ulaş Fidan, Nuri Yiğit, Rıza Efendi Karaca, Ali Ergün

“…Additionally, surgical information has to be had for surgical exploration and pelvic anatomy.…”
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Personalized prediction of anticancer potential of non-oncology drugs through learning from genome derived molecular pathways by Xiaobao Dong, Huanhuan Liu, Ting Tong, Liuxing Wu, Jianhua Wang, Tianyi You, Yongjian Wei, Xianfu Yi, Hongxi Yang, Jie Hu, Haitao Wang, Xiaoyan Wang, Mulin Jun Li

“…Utilizing protein–protein interaction networks, CHANCE harmonizes multilevel mutation annotations and integrates pharmacological information across different drugs into a single model. …”
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A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis by Krishnan Sircar, Dorothee Jochimsen, Charlotte Meyer-Schwickerath, Norma Jung, Nikolaus Kernich, Peer Eysel, Ayla Yagdiran

“…These results can be used to individualize patient information and provide a better assessment of prognosis before surgery.…”
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Exploring the possible two-proton radioactivity of 38,39Ti by B. Huang, F.P. Bai, J.G. Li, D.Q. Fang, S.M. Wang

“…To provide more accurate information for further studies, we utilize the Gamow shell model (GSM) and the Gamow coupled channel (GCC) method to analyze the prospective 2p radioactivity of isotopes 38,39Ti. …”
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Comparative Analysis of AES, Blowfish, Twofish, Salsa20, and ChaCha20 for Image Encryption by Rebwar Khalid Muhammed, Ribwar Rashid Aziz, Alla Ahmad Hassan, Aso Mohammed Aladdin, Shaida Jumaah Saydah, Tarik Ahmed Rashid, Bryar Ahmad Hassan

“…Encrypt has grown into an answer that has become an essential element of information security systems. To ensure the security of shared data, including text, images, or videos, it is essential to employ various methods and strategies. …”
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Survey on the presence of floating microplastics, trace metals and metalloids in seawater from Southern Italy to the United States of America by Elisabetta Morici, Gaetano Cammilleri, Sergio Scirè, Francesco Paolo Bonomo, Luigi Tranchina, Francesca Terracina, Paola Galluzzo, Vincenzo Ferrantelli, Vincenzo Paolo Monteverde, Francesco Giuseppe Galluzzo, Sergio Davì, Mariano Licciardi, Salvatore Dara

“…The presence of microplastics (MPs), trace metals (TM) and metalloids (Ms) in surface seawater is a severe emerging issue of global concern. Information about the distribution of these pollutants is often lacking, and large-scale studies come with uncertainties because of difficult comparisons of results obtained using different methods to collect and process data. …”
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Gut microbiota dysfunction in Crohn’s disease by Sylvie Buffet-Bataillon, Sylvie Buffet-Bataillon, Gabriela Durão, Isabelle Le Huërou-Luron, Olivier Rué, Olivier Rué, Yann Le Cunff, Vincent Cattoir, Guillaume Bouguen

“…Virulence factors involved in host invasion, host evasion and inflammation were also increased in CS.ConclusionsThis functional metagenomic information provides new insights into community-wide microbial processes and pathways associated with CD pathogenesis. …”
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Sensory substitution and augmentation techniques in cerebral visual impairment: a discussion of lived experiences by Stephanie L. Duesing, Katie Lane-Karnas, Sebastian James Adam Duesing, Mae Lane-Karnas, Nai Y, Arvind Chandna, Arvind Chandna

“…As with other neurodiverse populations, research on CVI needs to be directly informed by the lived experiences of those affected—children, adults, and their families. …”
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Ultralight aircraft and conventional digital cameras as an alternative for urban mapping by Román Edén Parra-Galaviz, Manuel de Jesús Pérez-Valdez, Omar Llanes-Cárdenas, Lennin Enrique Amador-Castro, Rafael Macías-Segura, Ciro de la Concepción Díaz-Hernández, Alberto Gaxiola

“…Mapping plays a crucial role in urban planning by assisting authorities in making informed decisions regarding city growth and infrastructure placement. …”
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Preoxygenation strategies before intubation in patients with acute hypoxic respiratory failure: a network meta-analysis by Na Ye, Na Ye, Chen Wei, Jiaxiang Deng, Yingying Wang, Hongwen Xie

“…Model selection was based on the deviance information criterion (DIC).ResultsA total of 11 randomized controlled trials involving 2,874 patients were included. …”
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Estimation of evaporation in Andalusian reservoirs: Proposal of an index for the assessment and classification of dams by Santiago García-López, Marcia Salazar-Rojas, Mercedes Vélez-Nicolás, Jorge. M.G.P. Isidoro, Verónica Ruiz-Ortiz

“…New hydrological insights for the region: Data from 76 large dams in Andalusia, including their descriptive characteristics, morphometric details, and hydrological information, were retrieved from institutional sources. …”
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Distribution, traditional utilization, processing, and health benefits associated with the consumption of morama bean [Tylosema escululetum (Burch.)]: a survey from selected distri... by John Gwamba, Samuel Imathiu, John Kinyuru, Arnold Onyango, Masa Veronica Motaung

“…The survey sought to gather and document information about demographic characteristics, traditional use, cultural norms, harvesting, processing, preservation, and health benefits of morama beans. …”
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Evaluating the impact of drought and water restrictions on agricultural production in irrigated areas through crop water productivity functions and a remote sensing-based evapotran... by Joaquim Bellvert, Magí Pamies-Sans, Jaume Casadesús, Joan Girona

“…This approach offers valuable insights for water management agencies regarding the effects of water restrictions on crop yield losses, enabling them to make more informed decisions. Incorporating this methodology into emergency drought management plans is essential for fostering resilience in a changing climate.…”
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Steering conservation biocontrol at the frontlines: A fuzzy logic approach unleashing potentials of climate-smart intercropping as a component within the integrated management of f... by Komi Mensah Agboka, Henri E.Z. Tonnang, Emily Kimathi, Elfatih M. Abdel-Rahman, John Odindi, Onisimo Mutanga, Saliou Niassy

“…The index, validated through known push-pull testing sites and informed by insights from field data and practical observations, is primarily based on companion plants (Desmodium intortum and Brachiaria brizantha), livestock, and maize as covariates. …”
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Electroacupuncture for mild-to-moderate dry eye: study protocol for a multicentre, randomised, single-blind, sham-controlled trial by Yue Zhao, Guang Yang, Yun-Qiong Lu, Mei-Yan Li, Jue Hong, Yan-Ting Yang, Xue-Jun Wang, Xie-He Kong, Zhao Ma, Xin-Yun Huang, Yue-Lan Zou, Xing-Tao Zhou, Xiao-Peng Ma

“…The secondary outcomes include tear meniscus height, the Schirmer I test, corneal and conjunctival sensation, the ocular surface disease index, corneal fluorescein staining, the numerical rating scale and the Chinese DE-related quality of life scale.Ethics and dissemination The trial protocol and informed consent were approved by the Ethics Committee of Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine (identifier: 2021–119), Shanghai Eye Disease Prevention and Treatment Center (identifier: 2022SQ003) and Eye and ENT Hospital of Fudan University (identifier: 2022014).Trial registration number NCT05552820.…”
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Simulation of Software Development Team Productivity Incorporating Social and Human Factors: A System Dynamics Model by Luz Marcela Restrepo-Tamayo, Gloria Piedad Gasca-Hurtado, Johnny Valencia-Calvo

“…This paper presents a simulation model to support informed decision-making during planning, considering that non-technical factors, specifically social and human factors (SHF), can affect product delivery time. …”
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Estimation of population structure in emmer wheat germplasm conserved in the National Genebank of India by Jatin Tanwar, Sandhya Tyagi, Shivani Sharma, Preeti Jakhar, Gaurav Kumar, Sherry R. Jacob, Amit Kumar Singh, Shailendra K. Jha, Jyoti Kumari

“…A total of 93 alleles were detected, with the highest polymorphic information content value (0.9912) observed for the Xcfd20 marker. …”
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