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  1. 11701

    The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy by Huihui Guo, Hongsheng Xie, Yuanyuan Huang, Junxiang Jia, Xiangfei Kong, Qingliang Yang, Shun Gai, Wenjun Li, Lu Bai, Lingli Zhang, Xiaoxiao Chen, Zhicang Ye, Hangbo Ye, Linyao Zhao, Yifang Xu, Yong Du, Xiuzhen Zhang, Miaomiao Chen, Xiaomai Zhou, Robert Y. Zhao

    Published 2025-02-01
    “…Tub114, a novel Tubulysin B analog with a hydrophilic ethylene glycol moiety, has been conjugated to the anti-HER2 antibody DX-CHO9, forming the ADC DX126-262. This study examines the efficacy, pharmacokinetics, and safety profile of DX126-262, with a focus on Tubulysin-associated liver toxicity. …”
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    Article
  2. 11702

    CONSTRUCTIVE GEOMETRY IN IMPLEMENTATIONS OF MODERN 3D GRAPHICS by Ivan G. Lenchuk, Oleksandr O. Mosiiuk

    Published 2023-04-01
    “…In particular, the steps of creating a solid model of a pyramid, which is formed by cutting it off with a plane from a regular quadrangular pyramid, are illustrated by the basis of calculations and constructions, which are performed using techniques of constructive geometry. …”
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    Article
  3. 11703

    Mellom skrifta og barnet – tre barnehagelærarar sine strategiar i høgtlesing av bildebøker med få ord og med fleire ord by Anne Marta Vinsrygg Vadstein

    Published 2025-02-01
    “…The research utilizes two forms of empirical material: (1) Three ECEC teachers have filmed two reading sessions each – one of a book with fewer words and one book with more words, and (2) video-supported conversations with the teachers, offering reflections on the reading sessions. …”
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    Article
  4. 11704

    Trends in vegetation cover changes in Bonny area of the Niger Delta by A Adoki

    Published 2013-07-01
    “…The one–layered forest has mangrove trees of 3-14 m high without undergrowth forming the only layer while the two-layered forest has a top layer made up of Rhizophora species (3-32 m high) depending on the height of trees at each site and a ground layer composed mainly of the fern Acrostichum aureum and seedlings of the tree species. …”
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    Article
  5. 11705

    Exploring the antibacterial and anti-biofilm activity of two Iranian medical-grade kinds of honey on multidrug-resistant Pseudomonas aeruginosa by Mustafa Riyadh Alshaybawee, Shahrzad Asgari, Paria Ghadersoltani, Ahmadreza Mehrabian, Parastoo Saniee

    Published 2025-02-01
    “…Abstract Introduction Pseudomonas aeruginosa is a prominent multidrug-resistant and biofilm-forming bacteria. Mono-floral honey, enriched with a variety of biological compounds, can be categorized as medical-grade honey due to its notable pharmacological benefits. …”
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    Article
  6. 11706

    Population structure, selection signal and introgression of gamecocks revealed by whole genome sequencing by Naiyi Xu, Linyun Zhang, Feifan Chen, Zhengfu Feng, Jiangtao Zheng, DongHua Li, Yongju Zhao, Xiangtao Kang

    Published 2025-02-01
    “…Gamecocks are distributed worldwide, forming different breeds and strains. However, the single or multiple origin of global gamecocks has not been fully established and much remains unknown about genetic introgression events between gamecocks and other chickens. …”
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    Article
  7. 11707

    The sphingosine‐1‐phosphate signaling pathway (sphingosine‐1‐phosphate and its receptor, sphingosine kinase) and epilepsy by Lin Wang, Qingxia Kong, Xinyi Leng, Howan Leung, Yang Li

    Published 2025-02-01
    “…Sphingosine‐1‐phosphate (S1P) is an important lipid molecule. It not only forms the basis of cell membranes but is also an important bioactive mediator. …”
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    Article
  8. 11708

    Research of <i>PNPLA3</i> I148M Gene Polymorphism in Patients with Non-Alcoholic Fatty Liver Disease, with Liver Cirrhosis and with Hepatocellular Carcinoma by V. V. Petkau, G. A. Tsaur, E. N. Bessonova, A. A. Karimova

    Published 2023-11-01
    “…The study was conducted according to the “case-control” design, three main groups were formed: a group with NAFLD (n = 46), a group with LC (n = 61), a group with HCC (n = 50), as well as a control group (n = 70), for all groups we performed genotyping of the rs738409 polymorphism of the PNPLA3 gene. …”
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    Article
  9. 11709

    Variations in the physicochemical properties of soil, enzyme activities, and the characteristics of bacterial communities within algal biocrusts and subsoils across different plant... by Haonian Li, Zhongju Meng, Xiaomen Ren, Yanlong Han

    Published 2025-04-01
    “…Among them, the ABSCs in the community of H. scoparium are not conducive to forming bacterial network modularity (Modularity= 0.336 < 0.4). …”
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    Article
  10. 11710

    Laguna de fracasos by Lagunaries

    Published 2024-12-01
    “…We perform theories, we investigate modes of escaping the lineal narrativity, using polyphonic and choral forms of thinking / moving / saying / existing. We inhabit the irony of a virtuality that imposes a distance on us and at the same time it hacks all geographical borders. …”
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    Article
  11. 11711

    Analisis Forensik Digital untuk Investigasi Kasus Cyberbullying pada Media Sosial Tiktok by Halimah Septya Mikayla, Ari Kusyanti, Primantara Hari Trisnawan

    Published 2024-10-01
    “…Abstract TikTok is currently a widely popular social media platform among users and is also a media where various forms of cyberbullying are encountered. Cases of cyberbullying on TikTok can be subject to legal prosecution through digital forensic investigations. …”
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  12. 11712

    Results of Selective Biochemical Screening for Lysosomal Acid Lipase Deficiency and Sequencing of the <i>LIPA</i> Gene in the Risk Group Patients by S. V. Shtykalova, A. A. Egorova, O. S. Glotov, A. V. Kiselev, I. Yu. Kogan

    Published 2025-02-01
    “…Samples from 2805 patients are collected as dried blood spots on filter paper test forms. Biochemical study of the lysosomal acid lipase (LAL) enzyme activity was carried out according to Hamilton’s protocol of, using 4-methylumbelliferyl palmitate as a substrate and LAL inhibitor Lalistat-2. …”
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  13. 11713

    Fuzzy Inference System Mamdani dalam Prediksi Produksi Kain Tenun Menggunakan Rule Berdasarkan Random Tree by Tundo Tundo, Shoffan Saifullah

    Published 2022-06-01
    “…This method uses the concept of a random tree decision tree in forming rules. The rules are made based on the criteria in determining the amount of woven fabric production, including production costs, demand, and stock. …”
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  14. 11714

    Межмуниципальный анализ структуры и эффективности формирования бюджетов by Мария Александровна Печенская-Полищук

    Published 2024-12-01
    “…Cross-Municipal Analysis of Budget Structure and Forming Effectiveness // Research in Economic and Financial Problems. 2024. № 4. …”
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  15. 11715

    Antagonism of Eucalyptus endophytic fungi against some important crop fungal diseases by Parmida Aleahmad, Leila Ebrahimi, Naser Safaie, Hassan Reza Etebarian

    Published 2025-02-01
    “…Endophytic fungi colonize plants without causing symptoms, throughout or at least a significant part of their life cycle, forming a plant-fungal association. In this study, endophytic fungi were isolated from Eucalyptus camaldulensis trees, and their antifungal activity was evaluated against four significant plant pathogens namely Botrytis cinerea, Fusarium oxysporum f. sp. lycopersici, Macrophomina phaseolina, and Rhizoctonia solani. …”
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  16. 11716

    A Pilot Study Assessing Left Ventricle Diastolic Function in the Parasternal Long-axis View by Mümin Murat Yazici, Nurullah Parça, Enes Hamdioğlu, Meryem Kaçan, Özcan Yavas¸i, Özlem Bilir

    Published 2024-11-01
    “…The study population of 40 (included rate 14%) was formed after the exclusion criteria were applied to 285 patients who met these conditions. …”
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    Article
  17. 11717

    Distribution of Aeromonas bacterial population in water, sediment and Nile tilapia in fish culture pond, Guder, Ethiopia by Bekele Lema, Natarajan Pavanasam, Kassaye Balkew, Zufan Bedewi

    Published 2020-07-01
    “…The level of bacterial population in water, sediment and fish tissue were done by following standard methods and expressed as colony-forming units (CFU) in water per milliliter (CFU ml-1), sediment and fish tissues(CFU g-1).The results revealed more bacterial population in sediment (3.43 x106 to 5.54 x 106 CFU g-1) than in water (1.45x106 to 4.0x106 CFU ml-1) and  fish tissues (1.06 ± 1.10x104 to 1.74 ± 10.8x104 CFU g-1in gill filaments; 1.62 ± 11.2x104 to 2.82 ± 13.0x104 CFU g−1 in intestine from; and 0.82 ± 5.9x104 to 1.60 ± 12.1.6x104 CFU g-1; in kidney from 0.48 ± 5.0 to 0.77 ± 4.1x104 CFU g-1. in skin). …”
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  18. 11718

    Assessing the Suitability of Snail-Shell Powder as a Partial Replacement of Cement in Concrete Production. by Mukundane, Ivan

    Published 2024
    “…It makes any shape when cast in any formwork and forms a solid mass when cured at a suitable temperature and humidity This research titled “Assessing the suitability of snail-shell powder as partial replacement of cement in concrete” aims at the utilization of snail shells as a partial replacement of ordinary Portland cement. …”
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  19. 11719
  20. 11720