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  1. 11721
  2. 11722

    A mechanistic-statistical approach to infer dispersal and demography from invasion dynamics, applied to a plant pathogen by Saubin, Méline, Coville, Jérome, Xhaard, Constance, Frey, Pascal, Soubeyrand, Samuel, Halkett, Fabien, Fabre, Frédéric

    Published 2024-01-01
    “…By considering the whole range of possible dispersal processes our method forms a robust inference framework. It can be employed for a variety of organisms, provided they are monitored in time and space along a one-dimension invasion. …”
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  3. 11723
  4. 11724

    Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer by Claudia Duranti, Jessica Iorio, Valeria Manganelli, Giacomo Bagni, Rossella Colasurdo, Tiziano Lottini, Michele Martinelli, Chiara Capitani, Giulia Boso, Franco Nicolas D’Alessandro, Maurizio Sorice, Andrea Becchetti, Roberta Misasi, Tina Garofalo, Annarosa Arcangeli

    Published 2025-02-01
    “…Our study provides evidence that the complex formed by the hERG1 potassium channel and the β1 subunit of integrin receptors preferentially localizes in Lipid Rafts (LRs) in Pancreatic Ductal Adenocarcinoma (PDAC) cell lines and primary samples. …”
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  5. 11725

    Developing a risk score using liquid biopsy biomarkers for selecting Immunotherapy responders and stratifying disease progression risk in metastatic melanoma patients by Amalia Azzariti, Simona De Summa, Tommaso M. Marvulli, Ivana De Risi, Giuseppe De Palma, Roberta Di Fonte, Rossella Fasano, Simona Serratì, Sabino Strippoli, Letizia Porcelli, Michele Guida

    Published 2025-02-01
    “…Identifying biomarkers to predict patient response is crucial, ideally through non-invasive methods such as liquid biopsy. Methods Soluble forms of PD1, PD-L1, LAG-3, CTLA-4, CD4, CD73, and CD74 were quantified using ELISA assay in plasma of a cohort of 110 MM patients, at baseline, to investigate possible correlations with clinical outcomes. …”
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  6. 11726

    Synergistic photothermal conversion and visible-light photodegradation of antibiotic in S-type TiO2 derived Ti3C2-MXene loaded on NaYF4: Tm3+, Er3+, Yb3+ @BiOI by Seyyedeh Fatemeh Hosseini, Mir Saeed Seyed Dorraji, Shiva Mohajer, Seyedeh Narges Saeedi, Masoumeh Kianfar, Alexandr V. Koshelev, Nataliya A. Arkharova, Denis N. Karimov

    Published 2025-06-01
    “…In addition, the broad photoresponse range of TiO2 and the Schottky junction formed by Ti3C2 MXenes between TiO2 and BiOI facilitate charge separation while reducing photo-generated electron-hole pair recombination. …”
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  7. 11727

    Hard rock aquifer architecture and water circulation levels in the Strengbach critical zone observatory (France) by Chabaux, François, Négrel, Philippe, Gal, Frederick, Viville, Daniel, Ranchoux, Coralie, Van der Woerd, Jérome, Delay, Frederick, Ackerer, Julien, Aquilina, Luc, Diraison, Marc, Masson, Frédéric, Mériaux, Anne-Sophie, Labasque, Thierry, Lucas, Yann, Pezard, Philippe Adrien, Reuschlé, Thierry, Schmitt, Anne-Désirée, Stille, Peter, Wyns, Robert, Lerouge, Catherine, Dezayes, Chrystel

    Published 2023-11-01
    “…Such a difference is associated with the existence of a knickpoint in the river bed, separating a downstream zone marked by currently active erosion from an upstream one, less prone to erosion, with preserved reliefs formed around 20 ka ago.The water circulation scheme within the Strengbach watershed involves two different systems: a subsurface circulation within the shallow aquifer, corresponding to the mobile saprolite horizon and the saprock, and a deeper circulation in the fractured bedrock. …”
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  8. 11728

    FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms by Manish Kumar, Abhishek Singh Sengar, Anushree Lye, Pranesh Kumar, Sukhes Mukherjee, Dinesh Kumar, Priyadip Das, Suvro Chatterjee, Adele Stewart, Biswanath Maity

    Published 2025-03-01
    “…Intriguingly, we identified two parallel signaling cascades impacted by FNDC5 in cardiomyocytes: the ROS-driven intrinsic mitochondrial apoptosis pathway and the ROS-independent Ataxia Telangiectasia and Rad3-Related Protein (ATR)/Checkpoint Kinase 1 (Chk1) pathway. In fact, FNDC5 forms a co-precipitable complex with Chk1 alluding to possible intracellular actions for this canonically membrane-associated protein. …”
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  9. 11729

    Effect of Reforestation Tree Species on the Distribution and Stability of Purple Soil Aggregates by ZHONG Yujian, HE Feng, HAN Guangzhong, ZHAO Xia, YANG Fan

    Published 2024-12-01
    “…[Conclusion] The weathering of purple soil following afforestation provides the material foundation for aggregate formation, while the humus formed in the soil of artificial forests acts as a binding agent, promoting the formation of large aggregates and the maintenance of their stability.…”
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  10. 11730

    Uncovering the Hidden Physical Structures and Protostellar Activities in the Low-metallicity S284-RE Region: Results from ALMA and JWST by O. R. Jadhav, L. K. Dewangan, Aayushi Verma, N. K. Bhadari, A. K. Maity, Saurabh Sharma, Mamta

    Published 2025-01-01
    “…Analysis of the YSO distribution has revealed three active star-forming clusters (YCl1, YCl2, and YCl3) within the filament. …”
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  11. 11731

    Geological characteristics and main enrichment controlling factors of coalbed methane in Nanchuan area, southeastern Sichuan Basin by Xipeng HE, Kaiming WANG, Wei LUO, Yuqiao GAO, Nana LIU, Tao GUO, Yatong ZHOU, Didi WU

    Published 2025-01-01
    “…It is characterized by "high gas content, abundant free gas, and oversaturation", and its gas content increases with burial depth. (4) The in-situ stress in the study area is moderate (35 to 60 MPa), with a small two-way horizontal stress difference coefficient (< 0.1) and good roof and floor plates, forming effective stress shielding favorable for fracturing transformation. (5) The main controlling factors for CBM methane enrichment in the Nanchuan area include the sedimentary environment, which determines coal-bearing formations; the degree of coal evolution, which determines the intensity of hydrocarbon generation; and the preservation conditions, which govern CBM enrichment.…”
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  12. 11732

    Amebicidal and Antiadhesion Activities of Knema retusa Extract Against Acanthamoeba triangularis T4 Genotype on Contact Lenses and Modeling Simulation of Its Main Compound, E2N, Ag... by Watcharapong Mitsuwan, Imran Sama-ae, Suthinee Sangkanu, Dhrubo Ahmed Khan, Partha Biswas, Md. Nazmul Hasan, Julalak Chuprom, Tajudeen O. Jimoh, Christophe Wiart, Masyitah Binti Zulkipli, Nor Hayati Abdullah, Maria de Lourdes Pereira, Sonia M. Rodrigues Oliveira, Shanmuga Sundar Saravanabhavan, Polrat Wilairatana, Tooba Mahboob, Veeranoot Nissapatorn

    Published 2025-01-01
    “…Treated cysts exhibited wall disruption and dramatically showed forms of marked retraction. Treatment of Kre at 1/2 × MIC showed about 87% reduction in the trophozoite adhesion, while treatment at 2 × MIC exhibited a 59% reduction in the trophozoite adhesion to the plastic surface, compared with the control. …”
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  13. 11733

    Taung and beyond: The mining history, geology and taphonomy of Australopithecus in South Africa by Rieneke Weij, Stephanie E. Baker, Tara R. Edwards, Job Kibii, Georgina Luti, Robyn Pickering

    Published 2025-02-01
    “…To understand this rich and diverse fossil record, we must understand how the landscape formed (cave formation processes) and changed (mining), when this happened (geochronology), and how the fossils were accumulated and modified (taphonomy). …”
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  14. 11734

    Jianpi Yiqi Busui prescription alleviates myasthenia gravis by regulating Th17 through the TAK1/P38 MAPK/eIF-4E signaling pathway by Zhuming Chen, Jing Lu, Tianying Chang, Dongmei Zhang, Yibin Zhang, Miao Liu, Tong Wu, Peng Xv, Jian Wang

    Published 2025-02-01
    “…Western blot and immunofluorescence staining were used to detect the expression levels of key proteins and their phosphorylated forms, such as transforming growth factor beta-activated kinase 1 (TAK1), P38 mitogen-activated protein kinase (P38 MAPK), and eukaryotic initiation factor 4E (eIF-4E). …”
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  15. 11735

    Reflections on the Yoruba Past: Toyin Falola on Isaac Delano by Wale Oyedeji

    Published 2021-12-01
    “…But in today’s global setting they are also interpretable as having something to do with imperialism, its history, its new forms.”1 It thus seems that the generations that witnessed such unmistakable assault on their cultural heritage were not ready to accept it in good faith, and this provoked 1 Edward Said. …”
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  16. 11736

    Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro by Han T, Jia T, Wang J

    Published 2025-02-01
    “…Polymerase chain reaction assays and sequencing techniques were performed to detect well-known molecular determinants related to linezolid resistance, including the expression of optrA and cfr, mutations of 23S rRNA gene and ribosomal protein (L3, L4, L22) encoding genes (rplC, rplD, rplV).Results: After induction with sequentially increasing concentrations of linezolid, all four MRSA strains (L914, L860, L1096, and L2875) evolved into linezolid-resistant strains over various induction times (480, 384, 288, and 240 h) and universally formed small colony variants. A new mutation in the domain V region of 23S rRNA gene (C2404T) and one mutation in amino acid sequences of ribosomal protein (Met208Thr) were firstly identified among linezolid-resistant strains. …”
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  17. 11737

    Investigation of Potential Profiles and Influencing Factors of Voice Behavior among Chinese Nurses by Shuangying Huang, Hanwen Chen, Liyan Zhang, Xianming Weng, Lingming Zhou, Xiaoqin Ma, Weiyi Wang

    Published 2025-02-01
    “…By analyzing the potential profile of nurses' voice behavior, three potential categories were formed: low voice behavior group(C1, 21.1% of the total population), medium voice behavior group(C2, 60.9% of the total population), and high voice behavior group(C3, 18.0% of the total population). …”
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  18. 11738

    DIGITAL TOOLS FOR MATCHING QUALIFICATIONS TO THE LEVELS OF THE NATIONAL QUALIFICATIONS FRAMEWORK by Volodymyr Kovtunets, Sergiy Londar, Serhii Melnyk, Oles Kovtunets

    Published 2024-04-01
    “…Therefore, a user should be capable of forming at most four matrices of judgments and computing the main eigenvectors with some level of accuracy. …”
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  19. 11739

    Laser Based <sup>13</sup>C-urea Breath Test in Quantitative Assessment of Bacterial Colonization, Severity of Inflammation and Atrophy in Gastric Mucosa by E. V. Stepanov, V. T. Ivashkin

    Published 2023-02-01
    “…A total of 525 patients (301 men and 224 women) aged 15–80 years (median 39.8 ± 15.1 years) were examined. 239 (45.5 %) patients were diagnosed with chronic gastritis, chronic duodenitis (including erosive forms). In 286 (54.5 %) patients, peptic ulcer was diagnosed with localization in the stomach — in 42 (8 %), in the duodenum – in 238 (45.3 %), combined lesions — in 9 (1.7 %) cases. …”
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  20. 11740

    Rancang Bangun Protokol Perutean SDGR+R pada Vehicular AD-HOC Network Berbasis Arah by Eliyah Acantha Manapa, Sri Wahjuni, Shelvie Nidya Neyman

    Published 2020-12-01
    “…The latest technology for VANET communication is to use SDN-based geographic-based SDN (SDGR) as a control plane in controlling Ad-hoc communication between nodes. In forming the communication network topology, SDGR looks for the shortest path value between nodes and high node density. …”
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