Blood-based biomarkers in patients with non-small cell lung cancer treated with immune checkpoint blockade by Yo-Ting Tsai, Jeffrey Schlom, Renee N. Donahue

“…Further research aimed at longitudinal monitoring of circulating biomarkers is also crucial to comprehend immune dynamics and resistance mechanisms and should be used alongside tissue-based methods that interrogate the tumor microenvironment to guide treatment decisions and may inform on the development of novel therapeutic strategies. …”
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Evaluating the effectiveness of conservation priorities in mitigating agricultural threats to China’s vertebrates by Can Yang, Geli Zhang, Xi Zhang, Yuzhe Li, Zhichao Li, Qinghao Wang, Jinwei Dong

“…These findings provide critical insights that can inform strategies aimed at achieving the goals of the Kunming-Montreal Framework in China.…”
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Relationship between RSV-hospitalized children and meteorological factors: a time series analysis from 2017 to 2023 by Shuying Wang, Yifan Wang, Yingxue Zou, Cheng-liang Yin

“…This research intends to inform RSV prevention strategies, optimize public health policies and medical resource allocation while also promoting vaccine and therapeutic drug development. …”
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Individual variability in cortical representations of tonic pain by Bettina Deak, Anne Stankewitz, Astrid Mayr, Viktor Witkovsky, Pauline Jahn, Enrico Schulz

“…By contrast, this region was shadowed by a variety of activity patterns across individuals, represented by a low spatial correlation between group statistics and individual results.The current findings challenge the usefulness and applicability of group results. They do not inform us how pain is processed in the brain as none of the participants exhibited the processing pattern of the group statistics. …”
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Coproducing healthcare service improvement for people with common mental health disorders including psychotic experiences: a study protocol of a multiperspective qualitative study by Alexandros Georgiadis, Robbie Duschinsky, Jesus Perez, Peter B Jones, Debra Russo, Clare Knight, Emma Soneson, Mary Dixon-Woods

“…A new talking therapy could potentially benefit this group. Informed by principles of coproduction, this study will seek the views of service users and staff to inform the design and development of such a therapy.Methods and analysis Semistructured interviews will be conducted with IAPT service users, therapists and managers based in three different geographical areas in England. …”
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Economic Evaluations of Health Service Interventions Targeting Patients with Multimorbidities: A Scoping Literature Review by Lucia Ferrara, Vittoria Ardito, Valeria D. Tozzi, Rosanna Tarricone

“…More economic analyses are needed to inform evidence-based coverage decision-making.…”
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Estimating the Economic and Clinical Value of Reducing Antimicrobial Resistance to Three Gram-negative Pathogens in Japan by Tetsuya Matsumoto, Oliver Darlington, Ryan Miller, Jason Gordon, Phil McEwan, Takahisa Ohashi, Amer Taie, Akira Yuasa

“…**Discussion:** Learnings from this study can be used by the Japanese government to help inform decision-making on the strategies that may be included in the upcoming National AMR Action Plan and facilitate allocation of the required budget. …”
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Navigating the medical journey: Insights into medical students' psychological wellbeing, coping, and personality. by Aisha Ali Hawsawi, Neil Nixon, Elena Nixon

“…This study aims to explore both negative and positive factors influencing medical students' psychological wellbeing, considering coping strategies and personality traits to inform targeted support measures for diverse student needs.…”
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Irrational medicine use and its associated factors in conflict-affected areas in Mali: a cross-sectional study by Mohamed Ali Ag Ahmed, Alassane Seydou, Issa Coulibaly, Karina Kielmann, Raffaella Ravinetto

“…Our findings provide a solid basis for more targeted and multidisciplinary research, to further inform relevant stakeholders on how best to mitigate the impact of conflict on the rational use of medicines.…”
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Assessment of Student IPEC Competency Using Observer-Based Evaluation in Didactic Interprofessional Education Activities by Jacqueline Zeeman, Kimberly Sanders, Tia Belvin, Philip Rodgers

“…I-CATIS can supplement and advance student self-evaluation data and inform didactic IPE curriculum development to ensure graduates are prepared and competent to practice in a collaborative healthcare environment. …”
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Infection Dynamics of Severe Acute Respiratory Syndrome Coronavirus-2 Wild-type and Delta Variant of Concern in a Pediatric Cohort in Southern India by Asha Jyothi Penugonda, Deepayan Biswas, Murugan Thimiri Palani, Sangeetha Priya, Rajesh Kumar Subaschandrabose, Koshy Alan Valiaveetil, Belavendra Antonisamy, Rajeev Zachariah Kompithra, Leni Grace Mathew, Mahesh Moorthy

“…In mild-to-moderate disease, higher loads of Delta variant of concern resulted in robust antibody response that was absent in severe disease. These results could inform potential responses to future SARS-CoV-2 variants and may guide decisions on targeted vaccination in children.…”
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A Systematic Literature Review and Indirect Treatment Comparison of Efficacy of Repository Corticotropin Injection versus Synthetic Adrenocorticotropic Hormone for Infantile Spasms by Michael S. Duchowny, Ishveen Chopra, John Niewoehner, George J. Wan, Beth Devine

“…Our findings provide a blueprint to inform the design of future prospective studies for the treatment of infantile spasms.…”
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Parent skills training for parents of children or adults with developmental disorders: systematic review and meta-analysis protocol by Corrado Barbui, Chiara Servili, Brian Reichow, Cary Kogan, Isaac Smith, M Taghi Yasamy

“…Updates of the review will be conducted, as necessary, to inform and guide practice.Trial registration number PROSPERO (CRD42014006993).…”
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Microsimulation models on child and adolescent health: a scoping review protocol by Filipa Sampaio, Claire de Oliveira

“…In addition, we will use this information to guide the development of a microsimulation model on child and adolescent health for use in the Swedish context.Registration details https://osf.io/a8txn/…”
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Understanding repeated non-attendance in health services: a pilot analysis of administrative data and full study protocol for a national retrospective cohort by Alex McConnachie, Philip Wilson, Ross McQueenie, David A Ellis, Andrea E Williamson

“…We shall identify key factors associated with serial missed appointments and potential interactions that might predict them.Ethics and dissemination The results of the project will inform debates concerning how best to reduce non-attendance and increase patient engagement within healthcare systems. …”
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Poor school attendance and exclusion: a systematic review protocol on educational risk factors for self-harm and suicidal behaviours by Sophie Epstein, Emmert Roberts, Rosemary Sedgwick, Katie Finning, Tamsin Ford, Rina Dutta, Johnny Downs

“…Knowledge of this association could help inform suicide prevention strategies at clinical, school and population levels.Methods and analysis We will conduct a systematic search of Medline, EMBASE, PsycINFO, British Education Index and Education Resources Information Centre (ERIC) from 1 January 1990, and conduct a manual search for additional references. …”
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Biological age model using explainable automated CT-based cardiometabolic biomarkers for phenotypic prediction of longevity by Perry J. Pickhardt, Michael W. Kattan, Matthew H. Lee, B. Dustin Pooler, Ayis Pyrros, Daniel Liu, Ryan Zea, Ronald M. Summers, John W. Garrett

“…Here we show a personalized phenotypic CT biological age model that can be opportunistically-derived, regardless of clinical indication, to better inform risk assessment.…”
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Impact of non-pharmacological interventions on the first wave of COVID-19 in Portugal 2020 by Dinis B. Loyens, Constantino Caetano, Carlos Matias-Dias

“…This research will help inform future pandemic decision-making and infectious disease modeling worldwide.…”
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Evaluating different drought products for assessing drought and implications on agriculture in Nepal by Shishir Chaulagain, Manoj Lamichhane, Urusha Chaulagain, Sushant Gyawali, Sadina Shrestha, Vishnu Prasad Pandey

“…These findings suggest that further monitoring and forecasting of agricultural drought should incorporate SWDIgl due to its strong correlation with AWD. These insights can inform targeted interventions for winter wheat during their critical growth periods to mitigate drought effects in agriculture.…”
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Adherence Definitions, Measurement Modalities, and Psychometric Properties in HIV, Diabetes, and Nutritional Supplementation Studies: A Scoping Review by Burleson J, Stephens DE, Rimal RN

“…Julia Burleson, Daryl E Stephens, Rajiv N Rimal Department of Health, Behavior and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USACorrespondence: Julia Burleson, Email [email protected]: Measuring adherence has been a priority for researchers to help inform effective care for patients regularly consuming medications for chronic conditions. …”
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