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    Species specificity and specificity diversity (SSD) framework: a novel method for detecting the unique and enriched species associated with disease by leveraging the microbiome heterogeneity by Zhanshan Sam Ma

    Published 2024-12-01
    “…Majority of existing efforts have been focused on a community level, but the discerning power of community or holistic metrics such as diversity analysis seems limited. …”
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  18. 1378

    Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway by DanDan Liu, Hui Wang, Jialong Li, Siqi Sheng, Shu Wang, Ye Tian

    Published 2025-02-01
    “…Here, we present Non-lethal Sonodynamic Therapy (NL-SDT), in which ultrasound is used to activate locally sonosensitizers, thereby stimulating the production of reactive oxygen species for the purpose of modulating cell function or fate, as a novel methodology to inhibit progression of hypertensive renal fibrosis. …”
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    A CRISPR-Cas12a-based universal rapid scrub typhus diagnostic method targeting 16S rRNA of Orientia tsutsugamushi. by Bum Ju Park, Sang Taek Heo, Misun Kim, Jeong Rae Yoo, Eun Jin Bae, Su Yeon Kang, Sunghoon Park, Kyeo Re Han, Keun Hwa Lee, Jae Myun Lee, Hyeyoung Lee, Yoon-Jae Song

    Published 2025-01-01
    “…Here, we developed a CRISPR-Cas12a-based diagnostic method targeting the bacterial 16S rRNA to detect O. tsutsugamushi infection of all known genotypes. …”
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