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14921
Early and Late Complications Associated with Penile Cancer Surgery and the Impact of Human Papillomavirus Status: Findings from a Retrospective Norwegian Cohort Study
Published 2025-02-01“…The objective was to evaluate the early (≤30 d) and late (>30 d) complications and the impact of human papillomavirus (HPV) status. Methods: A retrospective analysis was conducted of a cohort consisting of 201 consecutive and treatment-naïve patients with PeCa/PeIN undergoing surgery (penile sparing, and partial and total amputation) between January 1, 2000 and December 31, 2023 at a tertiary centre as part of a centralised regional service. …”
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14922
Experimental study of the piezoelectricity of Middle Pleistocene loess in the Weibei region, China
Published 2025-01-01“…However, there is a lack of studies on the piezoelectricity of loess both domestically and internationally. MethodsThis study investigated the \begin{document}${\mathrm{Q}}_2^{{\mathrm{eol}}} $\end{document} loess from the Weibei Loess Tableland in Shaanxi Province as an example to explore the piezoelectricity of loess. …”
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14923
Photobiomodulation preconditioning for oral mucositis prevention and quality of life improvement in chemotherapy patients: a randomized clinical trial
Published 2025-02-01“…This trial aims to study the effect of preconditioning with photobiomodulation in preventing oral mucositis and xerostomia in cancer patients undergoing chemotherapy alone for the first time, and to examine its role in improving patients’ quality of life. Materials and methods This is a prospective, randomized, double-blind clinical trial including 45 patients divided into three age- and sex-matched groups. …”
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14924
Synthesizing the impact of armed conflicts on food security, livelihoods and social dynamics in Amhara region, Ethiopia
Published 2025-02-01“…The conflict management response and the scope of humanitarian assistance are also analyzed. Methods The study used a qualitative case study design. …”
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14925
Exome sequencing in Nigerian children with early‐onset epilepsy syndromes
Published 2025-02-01“…In this study, we employed ES to investigate the genetic basis of early‐onset epilepsy in 22 affected children from Nigeria. Methods The study involved sampling of patients diagnosed with early‐onset epilepsy syndromes at the Lagos State University Teaching Hospital (LASUTH) Neurology clinic. …”
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14926
Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi...
Published 2025-02-01“…Haiou Wang,1 Wenkang Huang,1 Xiaoya Pan,1 Meizi Tian,1 Jiahui Chen,1 Xiaotong Liu,1 Qin Li,1 Jianhua Qi,2 Yiping Ye,1 Lijuan Gao1 1School of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, People’s Republic of China; 2College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of ChinaCorrespondence: Lijuan Gao; Yiping Ye, Hangzhou Medical College, 182 Tianmushan Road, Hangzhou, Zhejiang, 310013, People’s Republic of China, Email [email protected]; [email protected]: To explore the protective effect and underlying mechanism of Quzhou Aurantii Fructus flavonoids (QAFF) on Ulcerative colitis (UC).Methods: The constituents of QAFF were accurately determined by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). …”
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14927
Weaving oral health provider perspectives to guide future dental therapy advocacy and implementation efforts
Published 2025-02-01“…The goal of this study was to explore oral health provider engagement and perspectives of DT implementation in local communities.MethodsEngagement related to DT from the dental provider perspective from the ADTA conference's attendees were analyzed via optional, electronic post-conference surveys. …”
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14928
Global, regional, and national burdens of leukemia from 1990 to 2019: A systematic analysis of the global burden of disease in 2019 based on the APC model
Published 2024-09-01“…To understand the current status and changing trends of the disease burden of leukemia at the global, regional, and national levels, and to provide a scientific basis for the development of leukemia prevention and treatment strategies. Methods Based on open data from the Global Burden of Disease Study 2019 (GBD 2019), R software was used to calculate estimated annual percentage changes to estimate trends in the age‐standardized incidence (ASIR) and the age‐standardized disability‐adjusted life years (DALY) rate due to leukemia and its major subtypes from 1990 to 2019. …”
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14929
Options of improvement of efficacy of gastroesophageal reflux disease treatment by dioctaedric smectite
Published 2015-10-01“…To analyze efficacy of heartburn relief and pathological gastroesophageal reflux (GER) elimination as well as dynamics of endoscopic changes at gastroesophageal reflux disease (GERD) under dioctaedric smectite (Smecta) treatment in standard doze as monotherapy and within complex mode of treatment.Material and methods. Overall 45 case records of GERD patients (25 women and 20 men, mean age 43,06 years) were analyzed. …”
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14930
Population Pharmacokinetic of Epidural Sufentanil in Labouring Women: A Multicentric, Prospective, Observational Study
Published 2025-02-01“…We aimed to develop a population PK model for epidural sufentanil in laboring women to evaluate the sufentanil placental transfer quantitatively.Patients and Methods: Forty-one participants who underwent epidural labor analgesia were recruited into this study. …”
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14931
Prevalence and factors associated with adverse pregnancy outcomes in South Africa: Evidence from the 2016 Demographic and Health Survey
Published 2024-06-01“…To determine the prevalence and factors associated with adverse pregnancy outcomes among women of reproductive age in South Africa, and to recommend strategies to reduce the burden of these outcomes. Methods. We conducted a secondary data analysis on women of reproductive age using data from the nationally representative, population- based, cross-sectional 2016 South Africa Demographic and Health Survey (SADHS). …”
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14932
CD36 inhibition enhances the anti-proliferative effects of PI3K inhibitors in PTEN-loss anti-HER2 resistant breast cancer cells
Published 2025-02-01“…Therefore, seeking for alternative combination therapy needs urgent attentions in PTEN-loss anti-HER2 resistant breast cancer. Methods Since remodeling of fatty acid (FA) metabolism might contribute to HER-positive breast cancer and is triggered by the PI3K signal pathway, herein, we examined the effects of the inhibition of endogenous FA conversion, SCD-1 or exogenous FA transport, CD36, in combination with PI3K inhibitors (alpelisib and inavolisib) in anti-HER2 resistant PTEN-loss breast cancer cells. …”
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14933
Assessment of Technology Readiness in Norwegian Older Adults With Long-Term Health Conditions Receiving Home Care Services: Cross-Sectional Questionnaire Study
Published 2025-02-01“…ObjectiveThe aim of this study was to understand the technology readiness level of a group of older adults who were provided home care services in order to address the present and future needs of this group in relation to the implementation of digital health care services. MethodsThis quantitative cross-sectional study included 149 older adults from Norway receiving home care services. …”
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14934
Hispanic Patients Undergoing Spinal Fusion for Neuromuscular Scoliosis Sustain Health Inequalities
Published 2025-01-01“…Our study aims to identify and describe those demographic factors associated with poor outcomes after spinal fusion with instrumentation in neuromuscular scoliosis to reduce health disparities and improve postoperative outcomes. Methods: A retrospective analysis was conducted using Healthcare Cost and Utilization Project data from 2016 to 2020, encompassing a random sample of 20% of procedures in the United States. …”
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14935
Occupational adjustments and work ability of young adult cancer survivors: results from the AYA-Leipzig study
Published 2024-12-01“…We therefore aimed to investigate the use of occupational adjustments and their impact on work ability upon return to work. Methods As part of the AYA-LE study, we surveyed AYA-CS (aged 18–39 at diagnosis) who returned to work and assessed work ability (Work Ability Index) as well as use and benefit of occupational adjustments. …”
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14936
Long-term results of treatment of right-sided colon cancer with mesocolic excision and D3-lymph node dissection
Published 2014-07-01“…To estimate efficacy of D3-lymph node dissection with mesocolic excision in comparison to standard surgical technique of right hemicolectomy for right colon cancer in long-term terms.Methods. Comparative analysis of the long-term results of treatment of right colon cancer at I–III stages with D2- and D3-lymph node dissections was carried out. …”
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14937
The immunogenicity of PRV ΔgE/TK/UL49.5 three-gene-deleted vaccine in mice
Published 2025-02-01“…The PRV UL49.5 protein can inactivate the transporter associated with antigen processing (TAP), thereby downregulating the cell surface expression of swine leukocyte antigen class I (SLA-I) to evade host immune surveillance. Methods In this study, based on the PRV ΔgE/TK strain, PRV ΔgE/TK/UL49.5 triple gene deletion strain was constructed through homologous recombination and deletion of the PRV UL49.5 gene by the Cre-LoxP system. …”
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14938
Effectiveness of a Social Cognitive Theory-based health education intervention on depression (SCODESS) among mothers of children with cancer in Klang Valley, Selangor, Malaysia-A q...
Published 2025-01-01“…<h4>Objectives</h4>This study aimed to develop, validate, implement, and evaluate the effects of a Social Cognitive Theory (SCT)-based health education intervention on depression (SCODESS), as well as cancer-related knowledge, self-efficacy, perceived stress, coping skills, and social support among mothers of children with cancer at University Hospitals in Klang Valley.<h4>Methods</h4>A quasi-experimental study was conducted with mothers from two University Hospitals in Klang Valley, Selangor. …”
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14939
Protective factors for suicidal ideation and suicide attempts in adolescence: a longitudinal population-based cohort study examining sex differences
Published 2025-02-01“…This study investigated the associations between protective factors in early adolescence and the subsequent outcomes of SI and SA a year later, while also examining sex differences in these associations. Methods This study utilized data from a representative sample at two timepoints, T1 (N = 2464, 50.8% females, mean age = 13.7, SD = 0.6) in 1998 and T2 (N = 2432, 50.4% females, mean age = 14.9, SD = 0.6) one year later, collected as part of the longitudinal Youth and Mental Health Study (YAMHS) in Norway. …”
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14940
Pancreatic cancer mortality in South Africa: A case-control study
Published 2023-12-01“…To identify factors associated with an increased risk of pancreatic cancer mortality in SA. Methods. A matched case-control study with 1:1 matching was conducted using data collected by Statistics SA from 1997 to 2016. …”
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