Effects of vitamin D supplementation in patients with rheumatoid arthritis: A systematic review and meta-analysis by Mahsa Ranjbar, Mehran Rahimlou, Maryam Fallah, Kurosh Djafarian, Hamed Mohammadi

“…We decided to run a systematic review and meta-analysis to investigate the relationship between vitamin D supplementation and the outcomes of adult patients suffering from RA. Methods: We searched electronic databases, using specific search terms in PubMed, Scopus, and ISI Web of Science, until May 2024. …”
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Impact of Pre-existing Type 2 Diabetes Mellitus and Cardiovascular Disease on Healthcare Resource Utilization and Costs in Patients With COVID-19 by Chi Nguyen, Christopher L. Crowe, Effie Kuti, Bonnie Donato, Rachel Djaraher, Leo Seman, Nancy Graeter, Thomas P. Power, Rinku Mehra, Vincent J. Willey

“…**Objective:** We compared healthcare resource utilization (HCRU) and costs in patients with COVID-19 and T2DM and CVD (T2DM + CVD), T2DM only, or neither T2DM nor CVD (T2DM/CVD). **Methods:** A retrospective observational study in COVID-19 patients using data from the Healthcare Integrated Research Database (HIRD®) was conducted. …”
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Who is to blame for the ‘problem’ of teenage pregnancy? Narratives of blame in two South African communities by Zoe Duby, Brittany Bunce, Chantal Fowler, Kate Bergh, Kim Jonas, Nevilene Slingers, Catherine Mathews, Fareed Abdullah

“…Abstract Background The framing of teenage pregnancy in social discourse influences the way in which adolescent girls and young women (AGYW) are treated, the extent to which they are supported, and to which they are able to engage with services and enact pregnancy prevention behaviours. Methods Through the analysis of data from a qualitative study conducted in the South African communities of Newcastle in KwaZulu-Natal and Moretele in the North-West province, we explored narratives of blame for teenage pregnancy. …”
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Health IT Implementation and the Impact of the COVID-19 Pandemic on Clinician-IT Dynamics: Qualitative Study by Adeola Bamgboje-Ayodele, Adrian Boscolo, Mitchell Burger, Owen Hutchings, Miranda Shaw, Tim Shaw, Amina Tariq, Sundresan Naicker, Steven McPhail, Melissa Baysari

“…ObjectiveThis study aimed to explore the impact of the pandemic on HIT implementation processes, including pre- and postimplementation phases, and identify the socio-technical factors that shaped health IT implementation during an unprecedented circumstance. MethodsParticipants were from one of two teams: (1) health care staff members (doctors, nurses, nurse unit managers, and support staff members) from a virtual hospital in Australia; and (2) IT professionals within the broader health care organization assigned to the hospital. …”
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Deformations and seepage-induced erosion of fractured rocks in fault under confined settings by Wenbin SUN, Dianjin TIAN, Cheng MA, Yanchao XUE, Can YANG, Kaipeng ZHU

“…In this case, the risks of mine water inrushes increase significantly due to the complex deep hydrogeological conditions, a significant increase in the number of hidden disaster-causing factors, and the existence of faults. MethodsUsing a deformation-seepage experiment system for fractured rocks, this study investigated the characteristics of compressive deformations and seepage-induced erosion of fractured rocks in faults. …”
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Perspectives of the COVID-19 pandemic and vaccination among racially and ethnically diverse gay, bisexual, and other men who have sex with men with and without HIV in the US South:... by Jake S. Waldman, Jorge Alonzo, Lilli Mann-Jackson, Sandy K. Aguilar-Palma, Manuel Garcia, Benjamin D. Smart, Scott D. Rhodes

“…Our community-based participatory research partnership sought to better understand perspectives about and experiences with the COVID-19 pandemic, COVID-19 vaccination, and related health care among GBMSM. Methods We collected, analyzed, and interpreted qualitative in-depth interview data from a diverse sample of GBMSM (N = 30) in North Carolina, USA. …”
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Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease by Tian Meng, Yazhou Zhang, Yuan Ye, Hui Li, Yongsheng He

“…Therefore, finding the mitochondrial and immune-related gene (MIRG) signatures in AD can be significant in diagnosing and treating AD. Methods In this study, the intersection of the differentially expressed genes (DEGs) from the GSE109887 cohort, immune-related genes (IRGs) obtained from WGCNA analysis, and mitochondria-related genes (MRGs) was taken to identify mitochondria–immune-related genes (MIRGs). …”
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Medico-ethnobotanical survey of medicinal plants used in the treatment of skin diseases in Tiruppur District, Tamil Nadu, India by Prakasam Radha, Chinniaya Udhayavani, Raju Nagaraj, Kumarasamy Sivaranjani

“…Background and purpose: The present study aimed to identify, collect, and document the existing folklore knowledge on the utilization of medicinal plants to treat various common skin diseases such as Paronychia, Wounds, Carcinoma, Fissure foot, Scabies, Eczema, Melasma, Alopecia, Ringworm, Herpes, Psoriasis, Vitiligo etc. amongst the indigenous communities of Tiruppur District, Tamil Nadu. Study methods: Medico-ethnobotanical survey was carried out from November 2017 to November 2020 in five blocks of Tiruppur District, Tamil Nadu, India. …”
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Evaluation of the antidiabetic and antinephritic effects of Pueraria tuberosa and Pterocarpus santalinus extracts co-encapsulated in nanostructured lipid carriers in streptozotocin... by Gyamcho Tshering Bhutia, Asit Kumar De, Manas Bhowmik, Pavia Bera, Tanmoy Bera

“…Study design: The in vivo study evaluated the therapeutic potential of NLCs loaded with hydroalcoholic extracts of P. tuberosa tubers (PTE) and P. santalinus heartwood (PSE) in managing DN over eight weeks in streptozotocin (STZ)-induced diabetic mice. Methods: The protective effects of PTE and PSE were evaluated in mice at a dose of 80 mg/kg body weight. …”
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Clinical Burden and Healthcare Resource Use of Asthma in Children in the UK by Gouia I, Joulain F, Zhang Y, Morgan CL, Khan AH

“…We assessed the clinical and economic burden of asthma in children in the UK to better understand the impact of pediatric asthma.Methods: This was a retrospective, case-matched, longitudinal analysis using the Clinical Practice Research Datalink GOLD database and linked patient-level data (Hospital Episode Statistics and Office for National Statistics datasets) of selected patient (aged 6– 11 years) records in 2017. …”
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Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis by Li-wei Huang, Hua-min Li, Bei He, Xiao-bo Wang, Qi-zhi Zhang, Wen-xing Peng

“…Therefore, it is crucial to investigate the prevalence of cardiovascular sequelae in COVID-19 patients and to determine whether COVID-19 infection acts as an independent risk factor for these outcomes. Methods This meta-analysis adhered to PRISMA guidelines and was registered in PROSPERO (CRD42024524290). …”
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The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

“…This study focused on exosomes derived from stem cells of human exfoliated deciduous teeth (SHED-MSC-EXOs) and their role in managing the balance of immunoregulatory macromolecules that play a role in the underlying immunoregulatory mechanisms in THP-1-derived M0/M1 macrophage cells.MethodsFlow cytometry confirmed the expression of CD14, CD68, CD80, and CD86 markers in these macrophages. …”
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Impact of measles vaccination strategies on vaccination rates in low-income and middle-income countries: a systematic review and meta-analysis by Andrew Hayen, Kiddus Yitbarek, Mirkuzie Woldie, Firew Tekle Bobo, Jane Frawley, Abela Mahimbo, Meru Sheel

“…We did a review to identify and synthesise scientific research that evaluated the impact and cost-effectiveness of measles vaccination strategies on measles vaccination coverage, timeliness, hospitalisation rates, and mortality.Methods In this review, we searched for English-language articles published between 2012 and July 2023 in eight databases, including PubMed, ProQuest, MEDLINE (Ovid), Embase (Ovid), CINAHL, Scopus, Web of Science and the Cochrane Database of Systematic Reviews. …”
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Soil warming increases the active antibiotic resistome in the gut of invasive giant African snails by Yiyue Zhang, Hong-Zhe Li, Martin Breed, Zhonghui Tang, Li Cui, Yong-Guan Zhu, Xin Sun

“…Known for harboring extensive antibiotic resistance genes (ARGs) and human pathogens, it remains uncertain whether global warming exacerbates these associated health risks. Methods We use phenotype-based single-cell Raman with D2O labeling (Raman-D2O) and genotype-based metagenomic sequencing to investigate whether soil warming increases active antibiotic-resistant bacteria (ARBs) in the gut microbiome of giant African snails. …”
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Sociodemographic disparities in influenza vaccination among older adults in United States by Huan Tao, Jin Chen, Xue Zhang, Xue Zhang, Tao Wang, Nenggang Jiang, Yongqian Jia

“…This study aims to evaluate the prevalence of influenza vaccination and examine sociodemographic disparities within a nationally representative sample.MethodsThis study is a cross-sectional study. We used the data from the Behavioral Risk Factor Surveillance System spanning the years 2011 to 2022. …”
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Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription by Lipeng Pei, Yan Zhu, Wenpeng Li, Bin Xu, Jingli Sun

“…Celastrol is a natural anti-cancer product from the Celastraceae plant family, while its role in UCEC has not been investigated. Methods UCEC cell lines Ishikawa and HEC-1-A were applied and treated with different concentrations of Celastrol. …”
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The Mycoplasma hyopneumoniae protein Mhp274 elicits mucosal and systemic immune responses in mice by Mengqi Xie, Zhongshun Huang, Yun Zhang, Yujie Gan, Huiying Li, Dan Li, Honglei Ding

“…The purpose of the present study was to evaluate the immune responses of immunodominant proteins Mhp170, Mhp274 and Mhp336 in BALB/c mice.MethodsThe recombinant Mhp170 (rMhp170), Mhp274 (rMhp274), and Mhp336 (rMhp336) proteins were purified from recombinant bacteria. …”
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“Sleepless nights are a daily reality for us” how women experiencing homelessness in Addis Ababa, Ethiopia describe street life: a photovoice study by Kalkidan Yohannes, Kalkidan Yohannes, Kalkidan Yohannes, Mats Målqvist, Hannah Bradby, Yemane Berhane, Dagmawit Tewahido, Dagmawit Tewahido, Sibylle Herzig van Wees, Sibylle Herzig van Wees

“…In this study, we aimed to describe women’s experiences of street homelessness in their own terms and their suggestions to address their unmet needs.MethodsThis photovoice study draws on photos, focus group discussions, and semi-structured interviews. …”
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Plasma Iron Levels at Early Breast Cancer Diagnosis Are Associated With Development of Secondary Metastases: A Single-Center Retrospective Cohort Study by Jasmine De Troy, Sarah-Maria Fendt, Sigrid Hatse, Patrick Neven, Ann Smeets, Annouschka Laenen, Hans Wildiers

“…Design: Retrospective single-center study. Methods: Patients with stage I to III breast cancer, diagnosed between 2007 and 2017, and with serum iron, transferrin saturation, and ferritin values available within 1.5 months before or after diagnosis were included. …”
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Distribution Pattern of Cadmium in the Profile of Shallow Fissure Soil and Its Influencing Factors in Karst Areas with High Geological Background by FAN Pingping, CHEN Jia, ZHANG Feng, NIU Yong, FANG Nufang, WU Zeyan, CAI Huayin

“…[Objective] To study the vertical distribution pattern of cadmium (Cd) in shallow karst fissure soil, analyze the impacts of various factors on the distribution of Cd in fissures, and provide a scientific basis for future research on the distribution pattern of Cd in underground fissure soil and the prevention and control of Cd pollution. [Methods] Taking the small watershed of Baobao Mountain in Weining County, a region with a typical high geological background in the northwest of Guizhou, as the research object, the total Cd concentration and speciation of Cd in shallow fissure soil, along with five soil property indicators such as pH value, organic matter content, cation exchange capacity (CEC), particle size, and aggregate were systematically analyzed. …”
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