Intranasal Testing and Treatment for Staphylococcus aureus With Intravenous Vancomycin and Intranasal Povidone-iodine Prior to Posterior Spinal Fusion: A Retrospective Cohort Study... by Jason Malone, DO, Alex Lee-Norris, DO, Austin Wynn, MD, Kaitlin Maher, PA-C, John Lovejoy, III, MD, Ryan Illgenfritz, MD, Margaret Baldwin, MD, Adriana Cadilla, MD, Kathryn Farrell, MSN, Emily Craver, MS

“…The goal of this research study was to analyze the isolated effect of presurgical S. aureus nasal testing and PI application prior to spinal surgery. Methods: This is a retrospective cohort study of children 8 to 18 years of age who underwent posterior spinal fusion from 2018 to 2020 at two standalone academic pediatric hospitals. …”
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The physiological responses to volume-matched high-intensity functional training protocols with varied time domains by Jessica S. Smith, Jessica S. Smith, Gabriella F. Bellissimo, Gabriella F. Bellissimo, Fabiano T. Amorim

“…., “every minute on the minute” [EMOM]) that may have significant effects on physiological responses.PurposeTo compare the physiological responses between two different HIFT workouts (EMOM and RFT) that were matched for total work volume (TWV).MethodsTwelve trained individuals (six males and six females) performed two HIFT protocols, EMOM and RFT. …”
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Association between cadherin-related family member 3 rs6967330-A and human rhinovirus-C induced wheezing in children by Hanhaoyu Fu, Ri De, Yu Sun, Yao Yao, Runan Zhu, Dongmei Chen, Yutong Zhou, Qi Guo, Linqing Zhao

“…However, the relation between rs6967330 variants of cadherin-related family member 3 (CDHR3) and wheezing induced by human rhinovirus (HRV)-C has not been determined. Methods A total of 11,756 respiratory specimens collected from hospitalized children with acute respiratory infections (ARIs) between September 2017 and March 2023 were screened for enterovirus (EV)/HRVs by the capillary electrophoresis-based multiplex PCR (CEMP) assay, and those positive only for HRVs were amplified and sequenced for HRV and CDHR3 genotyping. …”
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Ethnoracial disparities in childhood growth trajectories in Brazil: a longitudinal nationwide study of four million children by Helena Benes Matos da Silva, Rita de Cássia Ribeiro-Silva, Juliana Freitas de Mello e Silva, Irina Chis Ster, Poliana Rebouças, Emanuelle Goes, Maria Yury Ichihara, Andrêa Ferreira, Julia M. Pescarini, Rosemeire Leovigildo Fiaccone, Enny S. Paixão, Maurício L. Barreto

“…Objective We aimed to investigate child growth according to maternal ethnoracial group using a nationwide Brazilian database. Methods A population-based retrospective cohort study employed linked data from the CIDACS Birth Cohort and the Brazilian Food and Nutrition Surveillance System (SISVAN). …”
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High risk for life-threatening adverse events of fluoroquinolones in young adults: a large German population-based cohort study by Julia Wicherski, Jonas Peltner, Cornelia Becker, Katrin Schüssel, Gabriela Brückner, Andreas Schlotmann, Helmut Schröder, Winfried V. Kern, Britta Haenisch

“…Therefore, we aim to examine the association between fluoroquinolone exposure and potentially life-threatening adverse events stratified by age and gender in Germany. Methods We conducted an administrative cohort study using the active comparator new user design with a risk window up to 365 days between January 2013 and December 2019. …”
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Response of Soil Respiration to Snowfall in a Kubuqi Salix Plantation Forest of During Freeze-thaw Period by WANG Jixuan, LAN Xiaozhen, PEI Zhiyong, ZHANG Junyao, WANG Xinping, LI Ying, WANG Haichao, SUN Xiaotian, SUN Kai

“…[Objective] To investigate the changes of soil respiration in desert ecosystems and its relationship with environmental factors during the spring freeze-thaw period in arid and semi-arid regions, and to provide data support for the carbon budget of sandy land ecosystems in arid and semi-arid regions. [Methods] Soil respiration rates of salix plantations that were untouched and unlevelled stubble (ww), untouched and levelled stubble (wp), untouched and unlevelled stubble (zw), and levelled and levelled stubble (zp) were measured in the snow-free treatment by using the Li-6800 soil-carbon-water flux measurement chamber in the Salix Forest Germplasm Resource Bank of the Dalate Banner, Ordos, Inner Mongolia, and the atmospheric temperature, soil temperature and humidity were measured simultaneously. …”
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Inequalities in total fertility rate in Sierra Leone, 2008–2019 by Augustus Osborne, Umaru Sesay, Mohamed S. Bah, Camilla Bangura, Bright Opoku Ahinkorah

“…This study investigated the inequalities in total fertility rate among women in Sierra Leone between 2008 and 2019. Methods We utilized data from the three rounds of the Sierra Leone Demographic Health Survey conducted in 2008, 2013, and 2019. …”
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Spatial analysis of measles cases and vaccination coverage in the Somali region, eastern Ethiopia by Abdilahi Ibrahim Muse, Abdilahi Ibrahim Muse, Mahdi Yonis Kayat, Mohamed Harir Aden, Jemal Beksisa Shuramu, Shikur Mohammed, Musse Ahmed Ibrahim, Musse Ahmed Ibrahim, Binyam Mohammedbirhan Berhe, Ahmed Abdi Kalinle, Sahardiid Ali Abdilahi

“…It can be prevented by two doses of the measles vaccine, either alone or in combination with measles-rubella (MR), which is a low-cost strategy for lowering morbidity and mortality among children.ObjectivesTo conduct spatial analysis of measles cases and vaccination coverage in the Somali region, Eastern Ethiopia.MethodsThis retrospective study was done by using public health emergency directorate measles data from 2022 to 2023 and four years (July 2019–July 2023) of vaccination data from district health information system version 2.36. …”
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Development of delayed pulmonary toxicities and transcriptional changes in pre-existing interstitial lung disease mice after partial thoracic irradiation by Jiamei Fu, Xinglong Liu, Yuchuan Zhou, Shengnan Zhao, Liang Zeng, Yan Pan, Jianghong Zhang, Kevin M. Prise, Chunlin Shao, Yaping Xu

“…Appropriate management for them remains a challenge for clinicians due to treatment-related complications. Methods To elucidate the histopathological characteristics and molecular mechanisms responsible for this severe toxicity in vivo, C57BL/6J mice were used to develop different lung injury models, including radiation-induced lung injury (RILI), bleomycin-induced pulmonary fibrosis (BIPF), and severe radiation-related lung injury (sRRLI) murine model. …”
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Differential management and associations of dyslipidaemia and hypertension by glycaemic status in urban South Africans by N Peer, L Kotzé-Hörstmann, J Hill, A-P Kengne

“…To describe the management and associations of dyslipidaemia and hypertension in adults with KD, newly diagnosed diabetes (NDD) and normoglycaemia. Methods. This urban population-based cross-sectional study comprised participants with KD, NDD and normoglycaemia. …”
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A population-based study on the burden of hospitalized pediatric pneumococcal disease in Taiwan before and after the introduction of 13-valent pneumococcal conjugate vaccine into t... by Ting-An Yen, Jhong-Lin Wu, Chi-Chuan Wang, Ling-Ya Huang, See-Hwee Yeo, Dony Patel, Cindy Thiow Koon Lim, Hung-Wei Lin, Eriko Yamada, Isaya Sukarom

“…Abstract Background To estimate the burden of invasive pneumococcal disease, non-bacteremic pneumococcal pneumonia, and acute otitis media before and after inclusion of the 13-valent pneumococcal vaccine (PCV13) into Taiwan’s Childhood Immunization Program in 2015. Methods Episodes of eligible children aged < 18 years hospitalized with invasive pneumococcal disease, non-bacteremic pneumococcal pneumonia, or acute otitis media between 1 January 2011 and 31 December 2019 were identified from the National Health Insurance Research Database. …”
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Evaluating risk factors for Trastuzumab-Deruxtecan Pneumonitis in patients with metastatic breast cancer by Jonathan Henricks, Tyler Haddad, Omair Ahmed, Jonathan Schoenhals, Pavnesh Kumar, Ryan Wilson, Jianing Ma, Jing Gennie Wang, Michael Wert, Vincent Esguerra, Ian Bentley, Kai Johnson, Daniel Stover, Sachin R. Jhawar, Margaret Gatti-Mays, Kevin Ho

“…Currently, there is limited understanding of pre-treatment risk factors for pneumonitis associated with T-DXd. Methods Consecutive breast cancer patients who received at least one dose of T-DXd at a single academic cancer study between January 1, 2019, and February 20, 2024, were identified for analysis. …”
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Clostridium difficile-associated disease in versatile hospital patient population and risk factors for its development by Ya. N. Yarushina, G. B. Kolotova, V. A. Rudnov, V. A. Bagin

“…To estimate proportion of patients with Clostridium difficile-associated disease in the spectrum of patients of versatile hospital and reveal its risk factors. Material and methods. Retrospective analysis of 131 case records of the in-patients of Yekaterinburg City Hospital No. 40 for the year 2014 who developed diarrhea during antibacterial therapy was carried out. …”
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Nursing faculty readiness to teach online: a survey of nursing educators from Saudi Arabia and the UK by Mansour Mansour, Naim Abdulmohdi, Abd Alhadi Hasan, Hana Abu-Snieneh, Rani Shatnawi, Firas Taysir Abu-Sneineh, Sahar Elmetwally A. Badawi

“…Aim To examine the Nursing Faculty’s level of readiness to teach online among a sample of nursing educators from Saudi Arabia and the UK. Methods A convenient sample of 152 (46%) Nursing Faculty from five universities across Saudi Arabia and the UK completed Part 2 of The Faculty Readiness to Teach Online (FRTO)’ survey between February – June 2021. …”
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Effects of Ciprofol and Propofol General Anesthesia on Postoperative Recovery Quality in Patients Undergoing Ureteroscopy: A Randomized, Controlled, Double-Blind Clinical Trial by Shi S, Wu J, Wu Y, Han X, Dai H, Chen X, Sun Z, Wang F

“…Shuqi Shi,1,2,&ast; Jimin Wu,1,&ast; Yini Wu,1 Xin Han,1 Hong Dai,1 Xuedong Chen,3 Zhangnan Sun,4 Faxing Wang1,2 1Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 2Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Urology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 4Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Faxing Wang, Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, No. 15, Dazhong Street, Lishui, Zhejiang Province, 323000, People’s Republic of China, Email [email protected] Zhangnan Sun, Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China, Email [email protected]: This study compares postoperative recovery quality between Ciprofol and Propofol, providing a reference for the clinical application of anesthetics.Methods: We randomized 112 patients undergoing ureteroscopic surgery into two groups: the Ciprofol group (Group C), with an induction dose of 0.4 mg/kg and a maintenance dose of 0.8– 1.5 mg/(kg·h), and the Propofol group (Group P), with an induction dose of 2 mg/kg and a maintenance dose of 4– 10 mg/(kg·h). …”
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Provincial distribution and predictors of desire for more children among married and cohabiting women in Sierra Leone by Augustus Osborne

“…This study, therefore, examined the desire for more children and its predictors among women in Sierra Leone. Methods The study analysed the 2019 Sierra Leone Demographic and Health Survey data. …”
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Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection by Yin H, Li X, Lu D, Zhao X, Yang Z, Wang Z, Xu F, Chen Y, Li C

“…This study aimed to investigate the role of MR-1 and ROCK1 in the regulation of inflammation in AD and their potentialities as therapeutic targets.Methods: Researchers performed protein immunoblotting on aortic wall tissue from 10 patients who underwent aortic arch replacement and 10 patients who underwent coronary artery bypass grafting to examine the expression levels of MR-1, ROCK1, and inflammatory pathways in the aortas. …”
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Genetic characteristics of influenza A and B viruses circulating in Russia in 2019–2023 by Svetlana B. Yatsyshina, Anna A. Artamonova, Maria A. Elkina, Anna V. Valdokhina, Victoria P. Bulanenko, Aleksandra A. Berseneva, Vasily G. Akimkin

“…Objectives of the study include: analysis of influenza virus circulation in Russia in 2019–2023, phylogenetic and molecular analysis of hemagglutinin (HA) sequences of influenza viruses, detection of mutations associated with drug resistance to neuraminidase (NA) inhibitors and M2-protein (M2) ion channel inhibitors. Materials and methods. Biological samples containing RNA of influenza viruses were studied: 410 A(H1N1)pdm09, 147 A(H3N2) and 167 B(Victoria). …”
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Unraveling Online Mental Health Through the Lens of Early Maladaptive Schemas: AI-Enabled Content Analysis of Online Mental Health Communities by Beng Heng Ang, Sujatha Das Gollapalli, Mingzhe Du, See-Kiong Ng

“…ObjectiveWe aimed to uncover associations between EMSs and mental health problems within OMHCs and examine features of EMSs as they are reflected in OMHCs. MethodsWe curated a dataset of 29,329 posts from widely accessed OMHCs, labeling each with relevant schemas and mental health problems. …”
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Lactate Dehydrogenase-A-Forming LDH5 Promotes Breast Cancer Progression by Fang T, Hu L, Chen T, Li F, Yang L, Liang B, Wang W, Zeng F

“…We aimed to explore the roles of LDHA and LDH5 isoenzyme activity in BC, which provides a new insight into LDHA for the treatment of BC.Methods: The expression of LDHA in BC and its relationship with clinicopathological features were obtained from various databases including The Cancer Genome Atlas (TCGA), Human Protein Atlas (HPA), Breast Cancer-Gene Expression Miner (bc-GenExMiner), TNMplot, UALCAN. …”
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