Relationship between four healthy lifestyle factors and all-cause and cardiovascular disease mortality among residents aged 35 – 75 years in Hebei province by Yuhuan LIU, Lijuan TANG, Xiaoying LU, Jingjing ZHAO, Yajing CAO, Xiaoli LIU, Dongsheng JIANG

“…ObjectiveTo investigate the relationship between four healthy lifestyle factors and all-cause and cardiovascular disease (CVD) mortality among residents aged 35 – 75 years in Hebei province, and to provide scientific evidence for promoting healthy lifestyles. MethodsData were collected from 48 377 residents aged 35 – 75 years in 11 districts and counties of Hebei province (Daming county, Handan city; Qinghe county, Xingtai city; Xuanhua district, Zhangjiakou city; Yuhua district, Shijiazhuang city; Chengde county, Chengde city; Sanhe city, Langfang city; Quyang county, Baoding city; Huanghua city, Cangzhou city; Shenzhou city, Hengshui city; Zunhua city, Tangshan city; and Funing district, Qinhuangdao city) who participated in the National Early Screening and Comprehensive Intervention Program for High-Risk Populations of CVD from September 2016 to December 2022. …”
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Fatty Acids of Erythrocyte Membranes and Blood Serum as Possible Predictors of Exacerbation in Patients with Inflammatory Bowel Diseases by M. V. Kruchinina, M. F. Osipenko, A. I. Valuyskikh, E. Yu. Valuiskikh, I. O. Svetlova

“…Aim: to study the levels of fatty acids in the membranes of erythrocytes and blood serum in patients with inflammatory bowel diseases (IBD) examined over time, as possible predictors of exacerbation of the disease.Materials and methods. Over a period of 6–12 months, 24 patients (mean age — 38.2 ± 4.4 years) with IBD with of moderate and mild severity of the disease were examined, of which 10 patients had ulcerative colitis, 10 — Crohn’s disease, 4 — unclassified colitis: the first examination was in the acute stage, the second was in the remission stage. …”
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Editorial by Daniel Halliday

“…The contributions to this issue of the Intergenerational Justice Review represent the sort of work that can enhance the broader study of inherited wealth as a problem of distributive and intergenerational justice, but one where there is much to be learned from attention to the sort of details discussed in these articles.   Daniel Halliday, Guest Editor …”
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Prospective Single-Arm Study of Remifentanil-Propofol Anesthesia with Manual Right Hypochondrial Compression for Painless Gastroscopy in Obese Patients by Wang M, Tang J, Pan Z, Jiang H, Hu D, Zhu B, Liang Z, Zhao X, Li Y

“…This study aimed to determine the efficacy and safety of the novel Li anesthetic protocol for obesity (LAPO) which included remifentanil-propofol regimen, manual right hypochondrial compression (MRHC), easy-to-create mask, and jaw thrust at preoperative painless gastroscopy in obese patients.Patients and Methods: This prospective, single-center, single-arm trial recruited 106 participants underwent LAPO for gastroscopy. …”
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Assessment of Bowel Preparation Using Low-Volume Sulphate-Based Preparations in Comparison with Macrogols: A Multicenter, Randomized, Comparative Clinical Study of the 3rd Phase by E. D. Fedorov, V. V. Veselov, S. V. Kashin, E. V. Tikhomirova, A. V. Veselov, D. V. Zavyalov, A. Kornowski, T. E. Gorskaya, M. Volteau, T. Ponchon

“…Oral sulphate solution(OSS: sodium sulphate, potassium sulphate and magnesium sulphate) is a low-volume osmotic agent for cleansing the intestines.Aim: in a multicentre, prospective, randomized, 3rd phase study with two parallel groups, the effectiveness, safety and tolerability of OSS was evaluated in comparison with Macrogol 4000 with electrolytes (a reference preparation for bowel cleansing in Russia) in adult patients who were scheduled for routine diagnostic colonoscopy.Methods. This study was conducted in three Russian research centres during the March–December, 2015 period. …”
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Impact of healthy lifestyle on diabetes incidence among adults of different socioeconomic status in Guizhou province: a prospective cohort study by Yiying WANG, Min CHEN, Lieqiang ZHANG, Xin WANG, Wei ZHAN, Yunxi PAN, Xiaodeng ZHAO, Tao LIU

“…ObjectiveTo understand the impact of healthy lifestyle on diabetes incidence among adults with different socioeconomic status (SES) in Guizhou province and provide reference for diabetes prevention and control. MethodsA total of 9 280 permanent residents aged ≥ 18 years in Guizhou Province were recruited using multistage cluster random sampling. …”
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Influencing Mechanisms of Ecosystem Services on Net Carbon Sink Efficiency and Spatial Differentiation Thereof: A Case Study of the Shanghai Metropolitan Area by Haoyang SONG, Min WANG

“…Under the guidance of the carbon peaking and carbon neutrality goals, clarifying the positive impact of ecosystem services on net carbon sink efficiency in metropolitan areas and the spillover effect of ecosystem services can effectively contribute to regional ecosystem service enhancement, and realize efficient carbon sequestration and reduction in ecological space.MethodsSupported by multi-source panel data spanning the period from 2010 to 2020, this research takes the Shanghai Metropolitan Area as the research object and divides the research area into 40 research units. …”
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Lower incidence of hepatocellular carcinoma with tenofovir alafenamide in chronic hepatitis B: Evidence from a large-scale cohort by Hye-Jin Yoo, Jae-Young Kim, Jeong-Ju Yoo, Hye Won Lee, Sang Gyune Kim, Young Seok Kim

“…This study evaluated and compared the effects of TAF, tenofovir disoproxil fumarate (TDF), and entecavir (ETV) on HCC incidence using nationwide claim data. Methods: In total, 75,816 patients with treatment-naïve HBV were included in the study and divided into TAF (n = 25,680), TDF (n = 26,954), and ETV (n = 23,182) groups after exclusions. …”
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Association of accelerated phenotypic aging, genetic risk, and lifestyle with progression of type 2 diabetes: a prospective study using multi-state model by Lulu Pan, Yahang Liu, Chen Huang, Yifang Huang, Ruilang Lin, Kecheng Wei, Ye Yao, Guoyou Qin, Yongfu Yu

“…We aimed to assess these associations and examine whether these associations varied by genetic risk and lifestyle. Methods We conducted a prospective cohort study that included 376,083 adults free of T2D and diabetes-related events at baseline in UK Biobank. …”
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Las brechas laborales que afectan a las mujeres desde la perspectiva de las ciencias económicas: un análisis de la producción científica en la base de datos Scopus - Labor market g... by Emanuel José Maldonado, Denis González-Argote, Rolando Eslava-Zapata, Alfredo Javier Pérez-Gamboa

“…Methodology: A mixed-methods approach was applied, combining a bibliometric study with qualitative thematic analysis. …”
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Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta by Alessia Gallo, Josè Camilla Sammartino, Roberta Vazzana, Roberto Giambruno, Claudia Carcione, Nicola Cuscino, Salvatore Castelbuono, Vitale Miceli, Matteo Bulati, Daniele Lilleri, Irene Cassaniti, Pier Giulio Conaldi, Fausto Baldanti

“…The success of each VOC, as well as the virus fitness, were enabled by altered intrinsic functional properties and, reasonably, to virus antigenicity changes, conferring the ability to evade a primed immune response. Methods We analysed the gene expression profiles of monocyte-derived macrophages (MDM) isolated from whole blood of healthy participants exposed to the 5 different SARS-CoV-2 VOC: D614G, Alpha (B.1.1.7), Gamma (P1), Delta (B.1.617.2), and Omicron BA.1 (B.1.1.529), and to the HCoV-OC43 strain, a coronavirus already present in the population before the SARS-CoV-2 pandemic. …”
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The diagnostic value of the combined application of blood lipid metabolism markers and interleukin-6 in osteoporosis and osteopenia by Liping Fan, Jiahao Chen, Chong Chen, Yongwei Zhang, Yeqing Yang, Zhe Chen

“…Abstract Background This study aimed to analyse the relationship of the blood lipid profile and interleukin-6 (IL-6) with osteoporosis and osteopenia and to explore the predictive value of the combined application of these biomarkers in osteoporosis and osteopenia. Methods Data from 276 patients treated in the orthopaedics department were retrospectively analysed. …”
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Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects by P.S. Kheoane, K.C. Mokhetho, S. Mokhele, K.C. Mbara, C.M. Leonard, T.H. Gadaga, C. Tarirai

“…This study investigated the ex vivo p-glycoprotein inhibition and the in vitro inhibition of cytochrome P450 3A4 (CYP3A4) isoezyme by selected wild edible plants to identify potential food/herb-drug interactions. Methods: Ethanolic extracts of 30 wild edible plants sourced from Lesotho, Eswatini and the Limpopo province of South Africa were used for the study. …”
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ADMINISTRATIVE PREREQUISITES FOR FINANCIAL MANAGEMENT AND MARKETING OF SMALL BUSINESSES AT THE REGIONAL LEVEL by Natalia Koval, Oksana Kubai, Natalia Germaniuk

“…Thus, it can be argued that the financial management of a small enterprise includes the following basic principles, methods, forms of effective and rational management of financial resources and relations of the enterprise. …”
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Efficacy of 5 µg and 10 µg Dexmedetomidine as Adjuvants to 3 mL 0.5% Hyperbaric Bupivacaine in Pelvic and Lower Limb Orthopaedic Surgeries: A Randomised Clinical Study by Jigisha Bharatbhai Mehta, Shreya Jatin Patel, Nilesh Vrajmohan Shah, Dinesh K Chauhan, Sara Mary Thomas

“…Aim: To compare the effects of intrathecal 5 μg dexmedetomidine versus 10 μg dexmedetomidine as adjuvants to 3 mL of 0.5% hyperbaric bupivacaine in pelvic and lower limb orthopaedic surgeries. Materials and Methods: This randomised clinical and single-blind study study was conducted at the Operation Theatre (OT) complex of Dheeraj Hospital, SBKS, and MIRC, Sumandeep Vidyapeeth, Vadodara, Gujarat, India in the Department of Anaesthesia over a period of 18 months, from September 2022 to March 2024 and total of 82 patients scheduled for lower limb and pelvic orthopaedic surgery who were to receive spinal anaesthesia were divided into Group D1 and D2. …”
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Efecto de la gallinaza sobre Azotobacter sp., Azospirillum sp. y hongos micorrízicos arbusculares en un cultivo de cebolla (Allium fistulosum) by Sandra Patricia Montenegro-Gómez, Susana Gómez-Posada, Silvia Eugenia Barrera-Berdugo

“…La gallinaza fresca, debido a su rápida disponibilidad está siendo ampliamente utilizada como fuente exclusiva de nutrientes, especialmente nitrógeno (N), en el cultivo de cebolla (Allium fistulosum), sin embargo, problemas de toxicidad por sales y acumulación de metales pesados en plantas han sido detectados. El objetivo de este trabajo fue estimar el efecto de la gallinaza fresca y compostada sobre las bacterias Azotobacter sp. y Azospirillum sp., así como en el número de esporas de hongos micorrízicos arbusculares (HMA), en el cultivo de cebolla. …”
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Calidad del agua para consumo humano y protección de la vida acuática en el embalse Los Laureles de Tegucigalpa (2002-2016) by German Onil Rodríguez Cruz

“…[Metodología]: Los índices se calcularon utilizando el software WQI versión 1.2 a partir de información histórica generada por el Laboratorio del SANAA en tres puntos de muestreo (cortina, centro y cola) e incluyendo hasta 23 parámetros fisicoquímicos, microbiológicos, metales y metaloides. Se utilizaron tres directrices de calidad: una para uso de consumo humano, y dos para uso de protección de la vida acuática. …”
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Emission Factors of PAHs Components and Bioreactivity in PM2.5 from Biomass Burning by Xinye Zhu, Kin-Fai Ho, Tzu-Ting Yang, Vincent Laiman, Jian Sun, Zhenxing Shen, Hsiao-Chi Chuang

“…Abstract Biomass burning releases fine particulate matter (PM2.5), water-soluble inorganic ions (WSIs), metal elements, polycyclic aromatic hydrocarbons (PAHs) and other compounds, and it is one of the largest sources of carbonaceous aerosols. …”
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The Effect of Internal Control System on the Financial Performance of SACCOS in Rukiga District: A Case study of Rukiga SACCO in Rukiga District. by Katwesigye, Joshua

“…Some respondents showed that control environment factors include; integrity and ethical values of personnel responsible for creating, administering, and monitoring the controls commitment and competence of persons performing assigned duties, board of directors, or audit. …”
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Second-line treatment patterns and outcomes in advanced HCC after progression on atezolizumab/bevacizumab by Meng Wu, Claudia A.M. Fulgenzi, Antonio D’Alessio, Alessio Cortellini, Ciro Celsa, Giulia F. Manfredi, Bernardo Stefanini, Y. Linda Wu, Yi-Hsiang Huang, Anwaar Saeed, Angelo Pirozzi, Tiziana Pressiani, Lorenza Rimassa, Martin Schoenlein, Kornelius Schulze, Johann von Felden, Yehia Mohamed, Ahmed O. Kaseb, Arndt Vogel, Natascha Roehlen, Marianna Silletta, Naoshi Nishida, Masatoshi Kudo, Caterina Vivaldi, Lorenz Balcar, Bernhard Scheiner, Matthias Pinter, Amit G. Singal, Joshua Glover, Susanna Ulahannan, Fredrich Foerster, Arndt Weinmann, Peter R. Galle, Neehar D. Parikh, Wei-Fan Hsu, Alessandro Parisi, Hong Jae Chon, David J. Pinato, Celina Ang

“…We evaluated real-world treatment patterns and outcomes to investigate factors associated with post-progression survival (PPS). Methods: In this multicenter, international, retrospective study, we examined clinical characteristics and outcomes of patients with advanced HCC who progressed on first-line A/B. …”
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