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681
5-Fluorouracil-β-Cyclodextrin conjugates:Linker strategies to enhance the anticancer efficacy and reduce the side effects
Published 2025-03-01“…Additionally, the conjugate exhibited reduced cytotoxicity towards normal colon epithelial cells. Pharmacokinetic analyses revealed that 5-FUSA-β-CD and 5-FUBA-β-CD were eliminated slowly and their half-lives were longer than that of free 5-FU. …”
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682
Role of Intraoperative Left Ventricular Global Longitudinal Strain in Hemodynamic and Cognitive Outcomes in On-Pump Coronary Artery Bypass Surgery: A Prospective Observational Stud...
Published 2025-01-01“…Conclusions: In CABG surgeries, LVGLS was a predictor of adverse outcomes in both awake and anesthetized patients with normal LVEF.…”
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683
Влияние курсового приема L-орнитин- L-аспартата на фиброз и стеатоз печени у больных ассоциированной с нарушениями метаболизма жировой болезнью печени (неалкогольной жировой болезн...
Published 2021-12-01“…The control cohort included patients with liver steatosis S0–S1, absent liver fibrosis, normal liver function tests, clean history of liver disease, while MAFLD cohort gathered liver steatosis S2–S3 and METAVIR fibrosis F1. …”
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684
Optimization of the cholesterol gallstone model in C57BL/6 mice and evaluation of Lactobacillus intervention effects
Published 2025-02-01“…In this study, 8-week-old male C57BL/6 mice were randomly divided into four groups: a high-fat diet + saline group (HF-S), a high-fat diet + probiotic group (HF-P), a normal diet + saline group (ND-S), and a normal diet + probiotic group (ND-P), to assess the effect of probiotics on gallstone formation. …”
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685
Biogeochemical coupling of C/Fe in oil-polluted wetlands associated with iron reduction
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686
Lidocaine Versus Ketamine Pretreatment on Propofol Injection Pain
Published 2019-12-01“…In the normal saline pretreatment group 8.1% of the patient experienced severe pain, compared with 0% in the lidocaine and ketamine. …”
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687
Phlegmonous appendicitis as a variant of uncomplicated appendicitis
Published 2025-02-01“…Patients were classified based on histopathological findings into four groups: normal appendix, uncomplicated appendicitis, phlegmonous appendicitis, and complicated appendicitis. …”
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688
Factors Associated with Poor Ovarian Reserve in Young Infertile Women: A Hospital-based Cohort Study
Published 2023-04-01“…Materials and Methods: Women aged more than 21 years and <35 years without Polycystic Ovarian Syndrome (PCOS) or ovarian dysgenesis with normal male factor were included after ethical approval. …”
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689
Production of possible ΣcΣ¯c molecular states in nucleon-antinucleon collision
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690
Machine learning-random forest model was used to construct gene signature associated with cuproptosis to predict the prognosis of gastric cancer
Published 2025-02-01“…Abstract Gastric cancer (GC) is one of the most common tumors; one of the reasons for its poor prognosis is that GC cells can resist normal cell death process and therefore develop distant metastasis. …”
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693
Primary liver lymphoma: review of the literature and clinical case presentation
Published 2018-08-01“…Presence of multiple focal lesions in the liver and signs of progressive liver failure at normal level of tumor markers requires taking into account primary liver lymphoma in the spectrum of possible etiologies. …”
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694
Studying the impact of chitosan salicylaldehyde/schiff base/CuFe2O4 in PC3 cells via theoretical studies and inhibition of PI3K/AKT/mTOR signalling
Published 2025-02-01“…Moreover, the anti-proliferative effect of chitosan, chitosan salicylaldehyde, and chitosan salicylaldehyde/CuFe2O4 was evaluated in PC3 human prostate cancer cells and HSF normal human skin fibroblasts. After 48 h, PC3 cell proliferation was significantly inhibited by chitosan salicylaldehyde/CuFe2O4 and chitosan salicylaldehyde (IC50 = 35.3 and 45.55 µg/ml, respectively) without any effects on normal HSF cells. …”
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695
Nurses’ and nurse leaders’ perspectives on a health-promoting work environment: a meta-ethnographic study
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696
Facts about Potassium
Published 2014-10-01“…It is important because it helps regulate fluid and electrolyte balance, maintain normal blood pressure, transmit nerve impulses, control muscle contraction, and maintain healthy bones. …”
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697
Teen Relationship Abuse Research Study
Published 2012-08-01“…., researchers discovered deep and troubling evidence that today’s teens are not only experiencing dating violence, but are accepting it as normal.” This 2-page Family Album Radio transcript was written by Donna Davis and published by the UF Department of Family, Youth and Community Sciences, August 2012. …”
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698
Author Correction: Automatic detection and counting of wheat spike based on DMseg-Count
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699
Facts About Niacin
Published 2013-02-01“…Niacin also is needed for DNA repair and for the normal use of calcium in the body. This 2-page fact sheet was written by R. …”
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700
Bilateral Fracture Dislocation of Shoulder: A Rare Case
Published 2024-01-01“…Three months postinjury, the patient showed a good prognosis with near normal range of movements of the bilateral shoulder.…”
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