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Real-world outcomes with tisagenlecleucel in aggressive B-cell lymphoma: subgroup analyses from the CIBMTR registry
Published 2025-02-01“…Patients with DLBCL (vs HGBCL), complete response before infusion, prior autologous or allogeneic haematopoietic stem cell transplant and lactate dehydrogenase (LDH) within normal limits experienced more favourable efficacy outcomes, and those with Eastern Cooperative Oncology Group performance status of ≥2, ≥3 prior lines of therapy, elevated LDH and fludarabine-based lymphodepleting chemotherapy experienced less favourable safety outcomes.Conclusions This real-world study of tisagenlecleucel for patients with R/R DLBCL/HGBCL shows consistent efficacy and better safety outcomes than the pivotal trial. …”
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Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans
Published 2024-08-01Get full text
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1285
Teologiczny wymiar godów weselnych i oczyszczenia świątyni (J 2, 1–22)
Published 2017-04-01“…Zmartwychwstały Pan gromadzi narody, jednoczy ludzi z Bogiem i między sobą w sakramencie swojego Ciała i Krwi. On jest nową świątynią ludzkości. Stanowi to sens znaku oczyszczenia świątyni. …”
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1286
Rodzina XXI wieku w perspektywie nauczania Jana Pawła II
Published 2015-10-01“… Sobór Watykański II przyniósł nowa dynamikę, ukierunkowując Kościół na małżeństwo i rodzinę. …”
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Endoscopic Analysis of Microstructures of the Colon Mucosa on the Edge of the Post-Resection Defect as a Measure of Preventing Recurrence of Polyps after a Cold Polypectomy
Published 2020-05-01“…The difference between the spatial location of crypts in the rectum (the effect of “falling crypts”) was identified, which complicates the differential diagnosis of normal and residual tumor tissue. In the endoscopic diagnosis of the vascular pattern of the colon mucosa was determined that flat-elevated polyps have a fine capillary network, which reduces the risk of bleeding when use a cold resection method. …”
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Diagnostic accuracy of drooling, reluctance, oropharynx, others, and leukocytosis score as a predictor of mortality and complications following acute corrosive ingestion
Published 2023-10-01“…The majority of our patients had normal to Zargar grade 1 injury to the stomach and esophagus. …”
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Base editing HbS to HbG-Makassar improves hemoglobin function supporting its use in sickle cell disease
Published 2025-02-01“…Purified HbG appears normal and does not polymerize under hypoxia. The topology of the hemoglobin fold with the βΕ6Α mutation is similar to HbA in the oxy and deoxy states. …”
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The Impact of Bar-induced Noncircular Motions on the Measurement of Galactic Rotation Curves
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Hubungan Asupan Zat Besi, Vitamin C, dan Persen Lemak Tubuh dengan Kejadian Anemia pada Remaja Putri di Pondok Pesantren Askhabul Kahfi Kota Semarang
Published 2024-12-01“…Hasil: Karakteristik responden menunjukkan bahwa 33 responden (50,8%) memiliki asupan zat besi cukup, 35 responden (53,2%) memiliki asupan vitamin C cukup, 43 responden (66,2%) memiliki persen lemak tubuh normal, dan 42 responden (64,6%) tidak menderita anemia. …”
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Application of glycyrrhizinic acid in treatment of patients with alcoholic liver disease
Published 2009-02-01“…Patients were randomized by random sample method in two groups: I group (n=58) – an abstinence in combination to placebo (intravenous injection 20 ml of normal saline solution 2 times per week), II group (n=48) – abstinence in combination to intravenous injection of 2,5 g of phosphogliv 2 times per week. …”
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Proximity extension assay revealed novel inflammatory biomarkers for follicular development and ovarian function: a prospective controlled study combining serum and follicular flui...
Published 2025-02-01“…Olink proteomic proximity extension assay (PEA) technology was used to compare the differentially expressed proteins (DEPs), and patients were divided into two subgroups—the normal ovarian reserve (NOR) group and the DOR group—for further bioinformatics analysis and verification by enzyme-linked immunosorbent assay (ELISA).ResultsIn total, 16 DEPs were detected between the mature group and the immature group (FF), and 11 DEPs were detected between the ovulation group and the menstruation group (serum). …”
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Exploring the antibacterial and anti-biofilm activity of two Iranian medical-grade kinds of honey on multidrug-resistant Pseudomonas aeruginosa
Published 2025-02-01“…The results of honey tests correspond to the normal range (natural Honey) in the Council of the European Union. …”
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Immune imbalance in the pre-ovulatory follicular microenvironment of overweight and obese women during IVF
Published 2025-02-01“…Methods 32 women undergoing in vitro fertilization (IVF) were included, with 14 overweight or obese (OW) and 18 normal weight (NW) participants. Serum was collected before ovulation induction, follicular fluid (FF) and aspirates were obtained during oocyte retrieval for flow cytometry, cytokines, hormone, and lipid profiles measurement. …”
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Bright night sleeping environment induces diabetes and impaired glucose tolerance in non-human primates
Published 2025-02-01“…Animals were retrospectively divided into four groups according to glucose metabolic status by the end of the experimental session, spontaneous diabetes mellitus (SDM, N=11), light-induced diabetes (LID, N=83), impaired fasting glucose tolerance (IFG, N=36), and normal glucose tolerance (NGT, N=67). Data pertaining to the glucose metabolism such as concentrations of fasting glucose, glycosylated hemoglobin, plasma insulin and C-peptide were collected monthly and analyzed.Results1) Bright night exasperated glucose metabolism in individuals with pre-existing diabetes, led to premature death; 2) Stronger white light intensity-dependently induced diabetes and IFG in previous healthy monkeys: the brighter the light, the quicker the metabolism disturbance and IFG developed, and also the higher morbidity of LID and IFG; 3) Exposure to nocturnal light had a synergistic impairing effect on glucose metabolism with aging and weight. 4) Female were more susceptible to night brightness.ConclusionsLight in sleeping environment exacerbates glucose metabolism in individuals with pre-existing diabetes, leads to IFG and diabetes in healthy primates. …”
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Estimación de biomasa y carbono en árboles de Cupressus lusitanica Mill. en Costa Rica
Published 2023-05-01“…Los modelos se construyeron a través del método de mínimos cuadrados ordinarios en regresión simple, usando el diámetro normal como variable independiente y fueron seleccionados por medio de la sumatoria ponderada de los estadísticos calculados y el análisis gráfico de los residuos. …”
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Comparison of the Efficacy and Tolerability of Dienogest and Dienogest Plus Ethinylestradiol on Endometriosis Related-Pain
Published 2020-12-01“…Treatment of endometriosis can be either surgical, aiming to restore normal anatomy by removing endometriotic lesions, or hormonal. …”
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