International norms for adult handgrip strength: A systematic review of data on 2.4 million adults aged 20 to 100+ years from 69 countries and regions by Grant R. Tomkinson, Justin J. Lang, Lukáš Rubín, Ryan McGrath, Bethany Gower, Terry Boyle, Marilyn G. Klug, Alexandra J. Mayhew, Henry T. Blake, Francisco B. Ortega, Cristina Cadenas-Sanchez, Costan G. Magnussen, Brooklyn J. Fraser, Tetsuhiro Kidokoro, Yang Liu, Kaare Christensen, Darryl P. Leong, Mette Aadahl, Edimansyah Abdin, Julian Alcazar, Aqeel Alenazi, Bader Alqahtani, Cledir De A. Amaral, Thatiana L.M. Amaral, Alex Andrade Fernandes, Peter Axelsson, Jennifer N. Baldwin, Karin Bammann, Aline R. Barbosa, Ameline Bardo, Inosha Bimali, Peter Bjerregaard, Martin Bobak, Colin A. Boreham, Klaus Bös, João Carlos Bouzas Marins, Joshua Burns, Nadezda Capkova, Lilia Castillo-Martínez, Liang-Kung Chen, Siu Ming Choi, Rebecca K.J. Choong, Susana C. Confortin, Cyrus Cooper, Jorge E. Correa-Bautista, Amandine Cournil, Grace Cruz, Eling D. de Bruin, José Antonio De Paz, Bruno De Souza Moreira, Luiz Antonio Dos Anjos, María Cristina Enríquez Reyna, Eduardo Ferriolli, Gillian Forrester, Elena Frolova, Abadi K. Gebre, Atef M. Ghaleb, Tiffany K. Gill, Yasuyuki Gondo, M. Cristina Gonzalez, Citlali Gonzalez Alvarez, Mary K. Hannah, Nicholas C. Harvey, Jean-Yves Hogrel, Marie-Theres Huemer, Toshiko Iidaka, Lewis A. Ingram, Dmitri A. Jdanov, Victoria L. Keevil, Wolfgang Kemmler, Rose Anne Kenny, Dae-Yeon Kim, Tracy L. Kivell, Ingirid G.H. Kjær, Alexander Kluttig, Rumi Kozakai, Danit Langer, Lisbeth A. Larsen, Wei-Ju Lee, David A. Leon, Eric Lichtenstein, Bertis B. Little, Roberto Alves Lourenço, Rahul Malhotra, Robert M. Malina, Kiyoaki Matsumoto, Tal Mazor-Karsenty, Marnee J. McKay, Sinéad McLoughlin, Abhishek L. Mensegere, Mostafa Mohammadian, Virgilio Garcia Moreira, Hiroshi Murayama, Anne Murray, Anita Liberalesso Neri, Claudia Niessner, Gabriel Núñez Othón, Gabriel Olveira, Suzanne G. Orchard, Andrezj Pajak, Chan Woong Park, Julie A. Pasco, Maria E. Peña Reyes, Leani Souza Máximo Pereira, Annette Peters, Eric Tsz-Chun Poon, Margareth C. Portela, Jedd Pratt, Robinson Ramírez-Vélez, Wendy Rodríguez-García, Joanne Ryan, Mauricio A. San-Martín, Francisco José Sánchez-Torralvo, Mahnaz Saremi, Arno Schmidt-Trucksäss, Satoshi Seino, Shamsul Azhar Shah, Marc Sim, Bjørn Heine Strand, Mythily Subramaniam, Charlotte Suetta, Sophia X. Sui, Jonas S. Sundarakumar, Koya Suzuki, Abdonas Tamosiunas, Maw Pin Tan, Yu Taniguchi, Barbara Thorand, Anna Turusheva, Anne Therese Tveter, Jonathan Wagner, Dao Wang, Stuart J. Warden, Julia Wearing, Shiou Liang Wee, Leo D. Westbury, Agnieszka Wiśniowska-Szurlej, Alexander Woll, Noriko Yoshimura, Ruby Yu

“…We included full-text peer-reviewed observational studies that reported normative HGS data for adults aged ≥20 years by sex and age. …”
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Tanggung Jawab Pejabat Pembuat Akta Tanah (PPAT) Dalam Pembayaran Pajak Bea Perolehan Hak Atas Tanah dan Bangunan (BPHTB) Atas Transaksi Jual Beli Tanah dan/atau Bangunan di Kota P... by Reta Permata Kasman, Khairani, Syofiarti

“…Ini bertujuan untuk menganalisis Tanggung jawab dan akibat hukum PPAT dalam pembayaran Pajak BPHTB dengan tujuan memberikan efektivitas hukum suatu norma peraturan hukum dapat dilaksanakan mencapai tujuan yang diinginkan dalam masyarakat, termasuk memberikan jasa Pelayanan yang sehubungan pelaksana jabatan seperti mengurus Roya Sertipikat, peningkatan Hak Atas Tanah dari Hak Guna Bangunan Ke Hak Milik. …”
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Calidad del agua para consumo humano y protección de la vida acuática en el embalse Los Laureles de Tegucigalpa (2002-2016) by German Onil Rodríguez Cruz

“…Es decir, influyó más la cantidad de veces que un parámetro sobrepasó la norma que el número de parámetros fallidos. …”
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Impaired RelA signaling and lipid metabolism dysregulation in hepatocytes: driving forces in the progression of metabolic dysfunction-associated steatotic liver disease by Yihuai He, Jinlian Jiang, Lili Ou, Yunfen Chen, Aikedaimu Abudukeremu, Guimei Chen, Weiwei Zhong, Zhigang Jiang, Nuerbiye Nuermaimaiti, Yaqun Guan

“…During MASLD, there was a decrease in the expression of RelA and hepatocyte nuclear factor 1 alpha (HNF1α), with both factors showing mutual enhancement of each other’s expression under normal conditions. This synergistic effect was absent during hepatocyte steatosis. …”
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Free fatty acids may regulate the expression of 11β-hydroxysteroid dehydrogenase type 1 in the liver of high-fat diet golden hamsters through the ERS-CHOP-C/EBPα signaling pathway... by Dandan Liu, Peipei Tian, Yilin Hou, Tingxue Zhang, Xiaoyu Hou, Lifang Liu, Xiaolong Li, Kunjie Zheng, Chao Wang, Guangyao Song

“…Methods A total of 24 male Syrian golden hamsters (SPF grade) were selected and randomly divided into a control group (Con, n = 8) fed a normal diet, and a high-fat diet group (n = 16) fed for 12 weeks. …”
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EpCare: Prototipe Sistem Detektor Pre-Iktal Pasien Epilepsi Berbasis Fitur CSI dari Sinyal EKG 1 Kanal Menggunakan AD8232 by Diah P. Wulandari, Arief Kurniawan, Alvin Nathanael, Santi W. Purnami, Anda L. Juniani, Wardah R. Islamiyah

“…F-measure dari eksperimen yang menggunakan ambang batas dari orang normal sebesar 0.64, sedangkan F-measures dari eksperimen yang menggunakan ambang batas individual penderita epilepsy sebesar 0.50.   …”
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Multiomics identify the gene expression signature of the spinal cord during aging process by Lintao Xu, Jingyu Wang, Jinjie Zhong, Weiwei Lin, Gerong Shen, Ning He, Xingjia Mao, Chunyan Fu, Zhaobo Huang, Fengdong Zhao, Xin Ye, Yongjian Zhu, Mingzhi Zheng, Hui Li, Lin-lin Wang, Kai Zhong, Lijun Zhu, Ying-ying Chen

“…SiRNA and lentivirus experiments indicate that the overexpression of Fth1 in normal mixed glial cells reduces their sensitivity to ferroptosis, whereas Fth1 knockdown increases their sensitivity to ferroptosis. …”
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Spartina alterniflora invasion significantly alters the assembly and structure of soil bacterial communities in the Yellow River Delta by Pengyuan Sun, Yuxin Wu, Pengcheng Zhu, Jingfeng Wang, Jingfeng Wang, Xiaona Yu, Weihua Guo

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Efficacy and safety of glycyrrhizic acid and essential phospholipids (Phosphogliv) combination for alcoholic liver disease: results of the double-blind randomized placebo-controlle... by I. G. Bakulin, N. A. Bokhan, P. O. Bogomolov, N. I. Geyvandova, M. V. Matsiyevich, M. A. Vinnikova, V. G. Morozov, O. M. Khromtsova, G. S. Soldatova, O. Yu. Shiryayev, R. D. Ilyuk, K. V. Rybakova, A. G. Katkovskaya, S. V. Teplykh, A. A. Bagretsova, M. V. Krasnova, Ye. V. Alekseyeva, A. V. Anipchenko, Ye. V. Baskakov

“…In 24 wks in group A in comparison to the group B significantly lower mean ALT level was found: 35,2±29,4 U/l vs 48,4±36,1 U/l (р =0,044), AST level became normal in higher rate of patients: 69,4% vs 47,7% (р =0,034), that had more prominent decrease in gamma-glutamyltranspeptidase (GGT) level - 47,4±36,5% vs 25,1±63,9% (р =0,039), the rate of patients with Aktitest A2-A3 range decreased - 8,5% vs 21,4% (p…”
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Olfactory mucosa-mesenchymal stem cells with overexpressed Nrf2 modulate angiogenesis and exert anti-inflammation effect in an in vitro traumatic brain injury model by Zigui Chen, Chunyuan Zhang, Yuhua Fang, He Zhang, Jiawei Luo, Changfeng Miao, Jiale Li, Jun Peng, Yingqi Qiu, Ying Xia, Qisheng Luo

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Physiological and multi-omics analysis revealed the mechanism of arbuscular mycorrhizal fungi to cadmium toxicity in green onion by Kunhao Xie, Yixuan Chen, Xiaoqin Wang, Xiaoya Zhou, Yizhe Cheng, Xianchang Yu, Jun Wang, Mintao Sun, Yansu Li, Chaoxing He

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Lactate Dehydrogenase-A-Forming LDH5 Promotes Breast Cancer Progression by Fang T, Hu L, Chen T, Li F, Yang L, Liang B, Wang W, Zeng F

“…The activities of LDH isoenzymes in serum and tissues were measured in patients with BC and healthy controls.Results: Compared to normal tissues, LDHA expression was significantly higher in BC tissues. …”
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3D echocardiography derived reference values and determinants of left ventricular twist and torsion from the population-based STAAB cohort study by Julia Napp, Götz Gelbrich, Floran Sahiti, Vladimir Cejka, Dora Pelin, Lena Schmidbauer, Mengmeng Chen, Niklas Hitschrich, Marcus Schreckenberg, Stefan Frantz, Peter U. Heuschmann, Stefan Störk, Caroline Morbach

“…To facilitate respective attempts and to set an individual’s results in relation to a population-based reference, we derived normal values for twist and torsion from a sub-collective of healthy individuals.…”
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Electrocardiography-based artificial intelligence predicts the upcoming future of heart failure with mildly reduced ejection fraction by Dae-Young Kim, Sang-Won Lee, Dong-Ho Lee, Sang-Chul Lee, Sang-Chul Lee, Ji-Hun Jang, Sung-Hee Shin, Dae-Hyeok Kim, Dae-Hyeok Kim, Wonik Choi, Wonik Choi, Yong-Soo Baek, Yong-Soo Baek, Yong-Soo Baek

“…The AI-ECG encompasses a novel model that combines an automatic labelling preprocessing method with a transformer architecture incorporating a triplet loss for HFmrEF analysis.ResultsThe receiver operating characteristic analyses revealed that the area under the curve of AI-ECG for identifying all types of HF was acceptable [0.873, 95% confidence interval (CI): 0.864–0.893], while that for identifying patients with HFmrEF was relatively lower (0.824, 95% CI: 0.794–0.863) than that for those with HF with reduced ejection fraction (EF) (0.875, 95% CI: 0.844–0.912) and those with normal EF (0.870, 95% CI: 0.842–0.894). The analysis of ECG features showed significant increases in QRS duration (p = 0.001), QT interval (p = 0.045), and corrected QT interval (p = 0.041) with increasing “Severity by Euclidean distance”. …”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…Our study aimed to characterize the mutational landscape of cDLBCL using whole-genome sequencing of matched tumor-normal samples obtained from a cohort of 43 dogs previously enrolled in a clinical trial for which longitudinal follow-up was available. …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…Exposure to mixed NEOs during gestation resulted in elevated glucose levels and impaired insulin sensitivity in normal pregnant and GDM mice models. In addition, we found the metabolic disorders induced by NEOs were linked to the deterioration of BAT thermogenesis in vivo. …”
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Observed climate trends and farmers’ adaptation strategies in Dendi District, West Shewa Zone, Ethiopia by Busha Getachew, Gonfa Kewessa, Worku Hailu, Gezahegn Girma

“…As rain-fed crop production relies on the timely and normal distribution of rainfall, these events significantly disrupt agricultural operations, particularly in mid-altitude and lowland areas. …”
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Enhancement of CD8+T cell cytotoxicity activity by IFN-α implies alternative pathologic role in systemic lupus erythematosus by Chen-xing Zhang, You-ying Mao, Yu-pin Tan, Mei-yu Zhang, Kang Shao, Shu-jun Wang, Ping Ji, Jia-yuan Wang, Lei Yin, Ying Wang

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Implementasi Algoritma Naïve Bayes untuk Mendeteksi Resiko Tinggi Diabetes Melitus Pada Ibu Hamil (Studi Kasus : Puskesmas Kabupaten Malang) by Fatmawati Fatmawati, Satrio Agung Wicaksono, Satrio Hadi Wijoyo

“…Tidak semua kehamilan dapat berjalan dengan normal atau fisiologis pada saat proses persalinannya ada faktor risiko yang dapat mempengaruhinya. …”
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Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3 by Swapan Kumar Ghosh, Koushik Pandey, Madhuparna Ghosh, Pradip Kumar Sur

“…After 24 h of treatment, the percentages of cell growth inhibition of HeLa, MCF-7, and A549 cell lines by highest concentration (1500 µg. mL− 1) of F12 were 92.03 ± 6.21 a, 90.38 ± 4.53a, and 87.51 ± 5.36a % respectively and the IC50 values were 701 ± 11.54, 728.71 ± 10.53, and 806.88 ± 11.52 µg. mL− 1 respectively but the growth of normal cell HEK 293T was inhibited slightly (3.0%). …”
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