Ficus deltoidea standardized methanolic extract improves kidney structure and function against streptozotocin-induced diabetic nephropathy in rats by Nurdiana Samsulrizal, Noor Syaffinaz Noor Mohamad Zin, Nur Syimal`ain Azmi, Mohd Daud Bakar, Hafandi Ahmad, Yong-Meng Goh

“…Serum creatinine, urea, uric acid, total bilirubin, and urinary creatinine were measured to estimate kidney function. Enzyme-linked immunosorbent assays (ELISA) assessed the levels of oxidative stress, antioxidants, and apoptosis-related proteins in the kidney tissue. …”
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Multiparameter resting-state functional magnetic resonance imaging as an indicator of neuropsychological changes in Binswanger’s disease with mild cognitive impairment by Haiyi Zhang, Lu Zhang, Juan Lu, Jiajun Yue, Zhengzhen Yuan, Jidan Hu, Qi Yao, Yuting Fu, Guiquan Chen, Jiliang Fang, Jie Zhao

“…The multiparameter functional magnetic resonance imaging (fMRI) including amplitude of low-frequency fluctuations (ALFF), fractional amplitude of low-frequency fluctuations (fALFF), regional homogeneity (ReHo), independent component analysis (ICA), and edge-link analysis was utilized to explore the abnormal brain networks of BD-MCI patients. …”
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Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions by P. K. Chandra Sekar, R. Veerabathiran

“…Genetic research has identified pivotal variants — NOD2, ATG16L1, and IL23R — linked to IBD, influencing key pathways, such as autophagy, interleukin signaling, and bacterial management. …”
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BOOK REVIEW: CIPRIAN PORUMBESCU NECUNOSCUT (CIPRIAN PORUMBESCU UNKNOWN), PUBLISHING BY ED. LIDANA, SUCEAVA, 3 EDIŢII, 2011-2013 (ISSN: 2284-712X) by Gabriela COCA

“… In late May and early June of this year, organized by the Bucovina Cultural Center from Suceava, took place the third edition (2013) of the “Ciprian Porumbescu” European Festival of Arts, having among the guests of honour the Porumbescu’s family descendant, Mrs. Nina Cionca, author of a vast, detailed and richly illustrated monograph about Ciprian Porumbescu. …”
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von Willebrand factor polymorphism (rs1063856) as a risk factor for portal vein thrombosis in chronic liver diseases by Isis Samy Bedira, Olfat M. Hendy, Moones Abdelaal, Ashraf A. Basuni, Asma Ebrahim Gaber Koshoo, Alzhraa Alkhatib, Sally S. Mandour

“…Twenty patients with PVT-linked hepatocellular carcinoma (HCC) and 20 patients with non-HCC-PVT comprised the two subgroups from the 40 PVT patients. …”
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Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study by Lorena González, Carolina Gonzalez-Riano, Pablo Fernández-García, Rubén Cereijo, Aina Valls, Andrea Soria-Gondek, Nativitat Real, Belén Requena, Joan Bel-Comos, Patricia Corrales, David Jiménez-Pavón, Coral Barbas, Francesc Villarroya, David Sánchez-Infantes, Marta Murillo

“…Further research is required to clarify the direct effects of rhGH on specific lipid species and batokines, potentially addressing metabolic disturbances linked to obesity and aging.…”
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Prevalence and factors associated with alcohol use disorders among people living with HIV attending care and treatment centers at Kilimanjaro, Tanzania: A cross-sectional study. by Florian Emanuel Ghaimo, Ester Steven Mzilangwe, Samuel Chacha, Saidi Bakari Kuganda

“…These conditions are linked to increased morbidity and mortality among PLHIV and amplify sexual risk behaviors, thus exacerbating the transmission of HIV. …”
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Risk factors associated with high altitude sickness among travelers: A case control study in Himalaya district of Nepal. by Sishir Poudel, Laxman Wagle, Mukhiya Ghale, Tara Prasad Aryal, Sushan Pokharel, Binay Adhikari

“…Rapid ascent (Adjusted Odds Ratio [AOR]: 6.41, 95% Confidence Interval [CI]: 2.36-17.54), individuals with a previous history of illness (AOR: 10.20, 95% CI: 2.70-38.46), and failing to take prophylactic medication (AOR: 10.01, 95% CI: 1.896-10.680) were linked to an increased risk of altitude sickness. …”
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New Zealand policy experts’ appraisal of interventions to reduce smoking in young adults: a qualitative investigation by Janet Hoek, Heather Gifford, Jude Ball, El Shadan Tautolo

“…Participant selection was based on seniority and expertise and ensuring diverse perspectives were represented.Interventions We examined nine interventions that could either promote greater mindfulness or introduce barriers impeding smoking uptake: smoke-free outdoor dining and bars; no tobacco sales where alcohol is sold; social marketing campaigns; real life stories (testimonials); life skills training; raise purchase age to 21; tobacco-free generation; smokers’ licence; make tobacco retail premises R18.Results The policies perceived as more effective denormalised tobacco; made it less convenient to access and use; highlighted immediate disadvantages (eg, impact on fitness); aligned with young people’s values; and addressed the underlying causes of smoking (eg, stress). …”
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Regulation of adipocyte differentiation and lipid metabolism by novel synthetic chromenes exploring anti-obesity and broader therapeutic potential by Kewalin Inthanon, Natthawut Wong-a-nan, Srisulak Dheeranupattana, Andres Garcia Guerra, Neal M. Davies, Chatchai Kesornpun, Sasithorn Sangher, Prasat Kittakoop

“…This pioneering study represents the first exploration of synthetic chromenes as potential anti-obesity agents, unveiling the underlying molecular pathways governing adipogenesis and lipolysis. Twenty-nine chromenes were synthesized using green chemistry approaches, resulting in five novel compounds: 1, 2, 3, 4, and 5. …”
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Phytomedicine nanoformulations for Parkinson's disease by Chinthu V. Saji, K P Mohanakumar, Rajesh A Shenoi

“…In vitro studies demonstrated enhanced cellular uptake and neuroprotective effects, while in vivo models showed improved pharmacokinetics, BBB permeability and neuroprotective outcomes. Additionally, nine plant-derived compounds with potential effects against PD, but are not nanoformulated were investigated, highlighting their neuroprotective mechanisms but exposing the existing limitations. …”
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Assessment of Malaysia-wide PM2.5 Forecasts from a Global Model by Zhixian Tan, Mohd Talib Latif, Matthew J. Ashfold

“…In Malaysia, transboundary ‘haze’ episodes with elevated PM2.5 concentrations linked to fires are common, causing health and economic harms. …”
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Influence of teaching a structured and humanized method of care on the perception of medical student attitudes in the doctor-patient relationship. by Higor Chagas Cardoso, Edna Regina Silva Pereira, Viviane Soares, Marcelo Fouad Rabahi

“…<h4>Results</h4>Fifty-nine medical students participated in the study, with a mean age of 21.3 years (SD = 2.8) and a higher prevalence of female students (71.2%). …”
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Nrf2/cyclooxygenase 2 signaling in Cr(VI)-induced carcinogenesis by Lei Zhao, Yi-Fang Wang, Andrea Adamcakova-Dodd, Peter S. Thorne, Ranakul Islam, Ke Jian Liu, Fei Chen, Jia Luo, Ling-Zhi Liu

“…Long-term exposure to hexavalent chromium [Cr(VI)] has been linked to lung cancer, and cyclooxygenase-2 (COX-2) is a well-known inflammatory factor. …”
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Factors and barriers to sulfadoxine-pyrimethamine uptake for intermittent preventive treatment during pregnancy in Ghana by Akua Kumi Yeboah, Patrick Ohemeng Gyaase, Richmond Bediako Nsiah, Regina Amoa-Tutu, Saida Abdul-Rahman Zakaria, Lynna Naa Adede Obeng, Frank Prempeh, Phenihas Kwadwo Opoku, Amos Andoono, Gilbert Elara Dagoe, Kwame Kusi Agyemang, Jonathan Mawutor Gmanyami, Dominic Nyarko, Paul Kofi Awuah, Gifty Sefaah Owusu, Solomon Anum-Doku

“…Higher IPTp-SP uptake was positively linked to the perceived severity of malaria in pregnancy (AOR = 0.19, [95% CI 1.02–4.20], p = 0.045) and the perceived benefits of IPTp-SP (AOR = 0.39, [95% CI 0.19–0.78], p = 0.008). …”
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The internet gaming disorder and its associated factors among college students at Imam Mohammed Ibn Saud Islamic University, Riyadh, Saudi Arabia: A cross-sectional study by Khalid Bin Abdulrahman, Tariq Y. Alhomoud, Ismail S. Alateeq, Faisal N. Al-Mohaisen, Musab S. Alshamrani, Saleh I. Alhathlul, Mohammed Abdulaziz Khamsah

“…Negative social effects include arguing after gaming was significantly linked with higher IGD scores (P < 0.001). Conclusion: IGD was prevalent among college students. …”
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Stochastic processes govern gut bacterial community assembly in a Schistosoma mansoni-transmitting snail, Biomphalaria straminea. by Zhanhong Yuan, Jinni Hong, Jehangir Khan, Jinghuang Lu, Benjamin Sanogo, Zhongdao Wu, Xi Sun, Datao Lin

“…Furthermore, the significant difference in the proportions of dispersal limitation and undominated processes is linked to both adaptive and non-adaptive snails.<h4>Conclusions</h4>This study demonstrates that stochastic processes govern the assembly of the gut microbiota in B. straminea. …”
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Diabetes and tuberculosis: a systematic review and meta-analyis of mendelian randomization evidence by Ivaan Pitua, Raafidha Raizudheen, Mark Muyanja, Joseph Nyero, Morrish Okello Obol

“…This systematic review aimed to consolidate existing MR evidence on the causal link between DM (types 1 and 2) and TB. Methods A comprehensive search was conducted in PubMed, Embase, Google Scholar, and Web of Science, identifying MR studies investigating the causal association between DM and TB. …”
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NT5E (CD73) as a prognostic biomarker and therapeutic target associated with immune infiltration in lung adenocarcinoma by Leyan Chen, Tuoya Qi, Bishu Zhang, Xuelong Wang, Mingfeng Zheng

“…Elevated NT5E expression was significantly linked to multiple clinicopathological factors, including metastasis and pathological stage, and served as a strong predictor of poor prognosis in LUAD patients. …”
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Beyond nutritional immunity: immune-stressing challenges basic paradigms of immunometabolism and immunology by Edmund K. LeGrand

“…Immune-stressing addresses effector cell glycolysis at the infected site by noting that the high uptake of glucose linked with high output of lactic acid is an ideal double-pronged stressor targeting proliferating pathogens. …”
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