Knowledge of mothers on diaper dermatitis management and associated factors in Ethiopia by Atoma Negera, Midekso Sento, Gemechu Tola

“…Therefore, this study aims to assess the mothers’ knowledge of diaper dermatitis and the risk factors linked with the disease. Data was collected from 396 mothers who came for immunization services from August 01 to September 01, 2024, consecutively. …”
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A longitudinal cohort study on dispensed analgesic and psychotropic medications in older adults before, during, and after the COVID-19 pandemic: the HUNT study by Tanja Louise Ibsen, Ekaterina Zotcheva, Sverre Bergh, Debby Gerritsen, Gill Livingston, Hilde Lurås, Svenn-Erik Mamelund, Anne Marie Mork Rokstad, Bjørn Heine Strand, Richard C. Oude Voshaar, Geir Selbæk

“…Methods A prospective cohort study using baseline data from 10,464 participants (54% females, mean age 76 years [SD 5.8]) from the Norwegian Trøndelag Health Study (HUNT4 70+) linked with the Norwegian Prescription Database. Age- and education-adjusted Poisson regression was applied to examine changes in prescription fills, and multilevel mixed-effects linear regression was used to estimate the mean sum of defined daily dose (DDD) per person per period during the lockdown (March–September 2020) compared to that during the corresponding months (March–September) in 2019, 2021, and 2022. …”
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FoxA1 knockdown promotes BMSC osteogenesis in part by activating the ERK1/2 signaling pathway and preventing ovariectomy-induced bone loss by Lijun Li, Renjin Lin, Yang Xu, Lingdi Li, Zhijun Pan, Jian Huang

“…The majority of the genes with the highest rankings were linked with osteogenic differentiation, indicating that our approach is useful for identifying genes associated with ossification. …”
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Initial versus Subsequent Injury and Illness and Temporal Trends Among Professional Hockey Players by Chelsea Martin, Allison Lieb, John Tokish, Ellen Shanely, Stefan Kluzek, Gary Collins, Garrett Bullock

“…Temporal trends were reported. # Results Nine thousand, seven-hundred and thirty four injuries and illnesses were recorded. …”
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The serum hepcidin and the hepcidin/ferritin ratio in NAFLD: a systematic review and meta-analysis by Jingmin Song, Heqing Wang, Xiaolian Gao, Fen Yang, Xinhong Zhu, Guiyuan Qiao, Ting Gan, Junxiu Tao

“…Clinical studies have identified a potential link between abnormal iron metabolism and the high incidence of NAFLD; however, the results from clinical trials remain inconsistent. …”
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Isokinetic Assessment of Knee Flexor and Extensor Strength and Lower Extremity Flexibility Assessment of an NCAA Division III Men’s Soccer Team by Savanna Perkins, Paul Canavan

“…The mean Thomas test measurements were 3.6° away from the neutral position on the right and 1.6° on the left, with nine positive tests. There were no statistically significant differences between left and right knee extension or flexion PT/BW or H:Q ratios at either speed. …”
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Consideraciones sobre la oferta hídrica de los sistemas acuífero-humedal en la cuenca Magdalena-Cauca, Colombia, a partir de la interpretación de datos de los satélites GRACE by Silvana Bolaños-Chavarría, Teresita Betancur-Vargas, Juan F. Salazar-Villegas, Micha Werner

“…Se observó, además, una alta correspondencia entre los eventos ENSO y GWS, en especial, los fuertes eventos La Niña 2010-2011 y El Niño 2015-2016 que causaron fuertes estragos en el país, lo cual se evidencia, en mayor medida, en la zona de la Mojana ubicada al norte de la cuenca. …”
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Metabolites and lipid species mediate the associations of adiposity in childhood and early adulthood with mammographic breast density in premenopausal women by Kayla R. Getz, Myung Sik Jeon, Lili Liu, Lei Liu, Haixiang Zhang, Chongliang Luo, Jingqin Luo, Adetunji T. Toriola

“…This study offers insight into the biological mechanisms underlying the link between early-life adiposity and MBD, which can support future research into breast cancer prevention.…”
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Association between Loa loa microfilaremia and anatomical hyposplenia in a rural area of the Republic of Congo: a population-based cross-sectional study by Charlotte Boullé, Elodie Lebredonchel, Jérémy T. Campillo, Valentin Dupasquier, Marlhand C. Hemilembolo, Sébastien D. S. Pion, Jean Claude Djontu, Ludovic Rancé, Philippe Souteyrand, François Missamou, Michel Boussinesq, Francine Ntoumi, Cédric B. Chesnais

“…We hypothesized that there could be an association between Loa loa microfilarial densities (MFD) and lower spleen volume (SV) due to micro-obstruction linked to circulating microfilariae (mf). This could result in functional hyposplenia and a higher burden of infections. …”
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Apportioning and Locating PM2.5 Sources Affecting Coastal Cities: Ulsan in South Korea and Dalian in China by Eunhwa Choi, Kwonho Jeon, Young Su Lee, Jongbae Heo, Ilhan Ryoo, Taeyeon Kim, Chuanlong Zhou, Philip K. Hopke, Seung-Muk Yi

“…Abstract PM2.5 mass and its constituent species were analyzed in two coastal cities (Ulsan, South Korea, and Dalian, China) between July 13, 2018, and September 20, 2019. Ten and nine sources were identified in Ulsan and Dalian, respectively, using positive matrix factorization (PMF). …”
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UK medical students’ mental health and their intention to drop out: a longitudinal study by Asta Medisauskaite, Antonia Rich, Milou Silkens, Neha Lagisetty

“…This study seeks to explore the relationships between various mental health issues and dropout.Design This is a longitudinal study where medical students completed an online questionnaire between November 2020 and February 2021 and those who took part were invited (February–May 2021) to complete the questionnaire again 3 months later.Settings Students from nine geographically spread medical schools in the UK took part in this study.Participants 792 (71.16%) participants filled in the baseline questionnaire and 407 (51.39%) of these students completed the follow-up survey (385 participants were lost to follow-up).Outcome measures Dropout intentions.Exposures Various mental ill-health symptoms using validated scales: emotional exhaustion, insomnia, somatisation, hazardous drinking, anxiety/depression, anorexia tendencies, obsessive-compulsive disorder (OCD), paranoia and bipolar.Results A large number of students met the criteria for mental health disorders (eg, 54.1% insomnia, 37.9% anxiety/depression, 19.4% paranoia) and 19.4% (79) said that they considered dropping out from medical school. …”
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Large-scale screening of HIV-1 T-cell epitopes restricted by 12 prevalent HLA-A allotypes in Northeast Asia and universal detection of HIV-1-specific CD8+ T cells by Yan Ding, Jialai Yan, Ling Huang, Jinhong Yu, Yandan Wu, Chuanlai Shen, Anning Fang

“…This study aimed to identify T-cell epitopes derived from the GP160, GAG, and POL proteins of the HIV-1 strain, specifically linked to 12 prevalent HLA-A allotypes, that collectively represent approximately 91% of the total gene frequency in Northeast Asian populations.MethodsA total of 134 epitopes were predicted in silico and selected as potential candidates for further validation. …”
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Associations of Long-term PM10 Exposure with Mortality in Dialysis Patients: A Population Based Cohort Study by Shih-Feng Chen, Yu-Hui Chien, Yu-Chin Lai, Pau-Chung Chen

“…To address this gap, we conducted a retrospective cohort study, linking the Taiwan Air Quality-Monitoring Database (TAQMD) with the National Health Insurance Research Database (NHIRD) based on patients’ zip codes. …”
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Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer by Giovanni Pecoraro, Ilaria Leone, Silvia Nuzzo, Santiago Negueruela, Giovanni Smaldone, Lorena Buono

“…Functional assays demonstrated that circPCDH11Y plays a role in regulating the expression of key neuroendocrine markers, including synaptophysin (SYP), neuron-specific enolase (ENO2), prostate-specific antigen (PSA), Brain-Specific Homeobox/POU Domain Protein 2 (BRN2) and the linear form of Protocadherin 11 Y-Linked (PCDH11Y). Silencing circPCDH11Y delayed the expression of SYP, ENO2 and PCDH11Y, while increasing PSA and BRN2 transcriptional levels, indicating its involvement in promoting neuroendocrine differentiation. …”
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Age-related changes in DNA methylation in a sample of elderly Brazilians by Hayley Welsh, Caio M. P. F. Batalha, Weili Li, Nadja C. Souza-Pinto, Yeda A. O. Duarte, Michel S. Naslavsky, Esteban J. Parra

“…Methods DNAm profiles were collected approximately nine years apart from 23 elderly Brazilian individuals using the Illumina Infinium MethyationEPIC BeadChip. …”
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Associations between Children’s Exposure to PM2.5 and their Serum Inflammatory Responses in Taiwan by Wei-Jung Tseng, Jian-He Lu, How-Ran Chao, Ming-Hsien Tsai, Yu-Ting Chang, Liang-Jen Wang, Chih-Cheng Chen, Wan-Nurdiyana-Wan Mansor, Juliana Jalaludin, Chih-Lung Wang, Ying-I Tsai

“…Children’s serum TNF-α was significantly linked to PM2.5 exposure scenarios (p = 0.031) by the test of the multivariate analysis (adjusted R2 = 0.033, p = 0.039), but the other variables of age (p = 0.147) and gender (p = 0.291) were not statistically significant. …”
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Trisomy 21 screening with αlpha software and the Fetal Medicine Foundation algorithm by L Pistorius, C A Cluver, I Bhorat, L Geerts

“…Data from the three largest laboratories collected between 2010 and 2015 were linked with genetic tests to assess screen positive and detection rates. …”
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Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy by Jun Peng, Wenqi Zhao, Lu Zhou, Kun Ding

“…Then the cell viability, inflammatory factors, and the expression of epithelial–mesenchymal transition (EMT) and fibrosis markers were determined by using Cell Counting Kit-8 (CCK-8) assay, enzyme linked immunosorbent assay (ELISA), western blotting assays, respectively. …”
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Causal Effects of Sleep Traits on Angina Pectoris: Mediation by Cardiovascular Risk Factors by Zeng C, Ke Y, Li H, Zhang C, Chen J, Chen M

“…Chuanfei Zeng,* Yujia Ke,* Huan Li, Chi Zhang, Jian Chen, Mingkai Chen Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mingkai Chen, Email [email protected]: Angina pectoris (AP) is a major factor in heightened risk of cardiac arrest and has been previously linked to sleep patterns. It remains unclear if sleep traits play a role in the onset of AP. …”
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Interventions for SARS-CoV-2 prevention among Jailed adults: A network-based modeling analysis by Isaac Schneider, Karina Wallrafen-Sam, Shanika Kennedy, Matthew J. Akiyama, Anne C. Spaulding, Samuel M. Jenness

“…A reference scenario and nine intervention scenarios were simulated three hundred times to estimate the median and interquartile range (IQR) of the outcome measures. …”
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