Key experimental technologies and their development directions for the exploration and production of deep coalbed methane by Xia YAN, Fengyin XU, Xianyue XIONG, Feng WANG, Chunhu LI, Jiyuan ZHANG, Borui XU, Qianhui CHENG, Xiong HU, Xueguang ZHU, Wei LIANG, Pu YUAN, Yanqing FENG, Zhenji WEI

“…Furthermore, this study systematically analyzes the advances and challenges in experimental technologies for deep coals, involving the characterization of multi-scale pores and fractures, the assessment of absorption and gas-content properties, the mechanic characteristics and fracture propagation patterns of coals, and the dynamic patterns of fluid occurrence and production post-fracturing. …”
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Preferential flow in soils is key to the development of nebkhas in water limited regions by Weicheng Luo, Wenzhi Zhao, Ning An, Chengpeng Sun, Hong Zhou

“…The degree of preferential flow was highest in LN, intermediate in SN, and minimal in BD, and it decreased with an increase in precipitation. Infiltration patterns in SN and LN were dominated by preferential flow, while matrix flow dominated in BD. …”
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Optimizing Navigation Channels through Hydrodynamic and Sedimentation Modeling: A Case Study of the Barito River Estuary, South Kalimantan by Aulia De Silva Nusantara Candida, Khomsin, Aldila Syariz Muhammad, Cahyo Utomo Andik, Rafly Rahardian Muhammad

“…This study uses Delft3D software to model hydrodynamic and sedimentation patterns in the estuary. The model reveals significant variations in current speed and direction between tidal cycles and seasons. …”
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Impact of stock market indices and raw material prices on the yield movements of Caterpillar company securities by Petrović Nevena, Novićević-Čečević Bojana, Krstajić Goran

“…The model results can be analyzed to identify patterns, trends, and insights that may be useful for forecasting. …”
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Scientific mapping of experimental research on solar cookers: Global trends, evolution, and future directions by Flavio Odoi-Yorke, Bismark Baah, Richard Opoku

“…Bibliometric analysis was conducted using R software's Bibliometrix package, examining scientific production, global collaboration patterns, keyword dynamics, and thematic evolution. …”
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Divergence in photoreceptor cell death and neuroinflammation in transvitreal and transscleral subretinal delivery in mice by Daniel E. Maidana, Sara Pastor Puente, Catherine Wang, Shivam Chandra, Lucia Gonzalez-Buendia, Eleftherios Paschalis Ilios, Andrius Kazlauskas, Demetrios G. Vavvas

“…Further leukocyte immunophenotyping indicated divergent infiltration patterns, with the TS approach exhibiting higher proportions of neutrophils and macrophages/microglia-like cells, while the TV injections had higher CD45hi CD11b + Ly6G- Ly6C + infiltration. …”
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A minimal gene set characterizes TIL specific for diverse tumor antigens across different cancer types by Zhen Zeng, Tianbei Zhang, Jiajia Zhang, Shuai Li, Sydney Connor, Boyang Zhang, Yimin Zhao, Jordan Wilson, Dipika Singh, Rima Kulikauskas, Candice D. Church, Thomas H. Pulliam, Saumya Jani, Paul Nghiem, Suzanne L. Topalian, Patrick M. Forde, Drew M. Pardoll, Hongkai Ji, Kellie N. Smith

“…Putative tumor-reactive cells (pTRC) identified via MANAscore in anti-PD-1-treated lung tumors had higher expression of checkpoint and cytotoxicity-related genes relative to putative non-tumor-reactive cells. pTRC in pathologically responding tumors showed distinguished gene expression patterns and trajectories. Collectively, we show that MANAscore is a robust tool that can greatly enrich candidate tumor-specific T cells and be used to understand the functional programming of tumor-reactive TIL.…”
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Oncogenic PIK3CA corrupts growth factor signaling specificity by Ralitsa R Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, Shaozhen Yin, Jahangir Sufi, Xiao Qin, Salome J Zhao, Julia Gorczynska, Daniele Morelli, Lindsay Davidson, Erik Sahai, Viktor I Korolchuk, Christopher J Tape, Bart Vanhaesebroeck

“…Abstract Technical limitations have prevented understanding of how growth factor signals are encoded in distinct activity patterns of the phosphoinositide 3-kinase (PI3K)/AKT pathway, and how this is altered by oncogenic pathway mutations. …”
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Membrana preformativa: Unveiling the unexplored facets of dental development by Sakshi Sikaria, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar

“…This study aims to provide detailed insights into the expression patterns and functional significance of Ki67 and Cyclin D1 in tooth development. …”
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Integrated multi-omics analysis reveals the underlying molecular mechanism for the neurotoxicity of triclosan in zebrafish by Shasha Zhao, Yuhang Ling, Baohua Zhang, Danting Wang, Limei Sun

“…Transcriptomics indicated that immune- and metabolism-related gene expression patterns were severely disturbed by TCS. Metabolomic analysis revealed 82 distinct metabolites in adult zebrafish exposed to TCS. …”
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Inferring 3D displacement time series through InSAR measurements and potential field theory in volcanic areas by Andrea Barone, Maurizio Fedi, Antonio Pepe, Pietro Mastro, Pietro Tizzani, Raffaele Castaldo

“…Then, we provide a 3-D ground displacement time series of the pre-eruptive displacement patterns related to the 2018 eruption at Sierra Negra volcano (Galapagos Archipelago, Ecuador). …”
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Compound events in Germany in 2018: drivers and case studies by E. Xoplaki, E. Xoplaki, F. Ellsäßer, F. Ellsäßer, J. Grieger, K. M. Nissen, J. G. Pinto, M. Augenstein, T.-C. Chen, T.-C. Chen, H. Feldmann, P. Friederichs, D. Gliksman, D. Gliksman, L. Goulier, K. Haustein, K. Haustein, J. Heinke, L. Jach, F. Knutzen, S. Kollet, J. Luterbacher, J. Luterbacher, N. Luther, S. Mohr, S. Mohr, C. Mudersbach, C. Müller, E. Rousi, F. Simon, L. Suarez-Gutierrez, L. Suarez-Gutierrez, L. Suarez-Gutierrez, S. Szemkus, S. M. Vallejo-Bernal, S. M. Vallejo-Bernal, S. M. Vallejo-Bernal, O. Vlachopoulos, F. Wolf

“…We provide new insights into the drivers of spatially and temporally compound events, such as heat and drought, and heavy precipitation combined with extreme winds, and their adverse effects on ecosystems and society, using large-scale atmospheric patterns. We also examine the interannual influence of droughts on surface water and the impact of water scarcity and heatwaves on agriculture and forests. …”
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The geographical variation in grassland forage quality on the eastern Qinghai-Tibet Plateau is driven mainly by climate by Shulan Wu, Xiaotao Lü, Qinghua Liu, Erke Wuda, Liu Li, Chunzhang Zhao, Juanjuan Huang, Shuang Li, Youbang Hu, Wenzhi Du, Hewen Li, Chaoqun Chen, Lin Luo, Ali Raza, Chunying Yin

“…Climate and plant community composition directly controlled the geographical patterns of forage quality. Climate had larger contribution to forage quality than soil and plant community composition. …”
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Economic Evaluations of Health Service Interventions Targeting Patients with Multimorbidities: A Scoping Literature Review by Lucia Ferrara, Vittoria Ardito, Valeria D. Tozzi, Rosanna Tarricone

“…Introduction: Multimorbid patients have been growing, leading to an exponential increase in healthcare costs and patterns of resource utilization. Despite the heightened interest toward integrated care programs as a response to the complex need of multimorbid patients, economic evaluations of these programs remain scarce. …”
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Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinoma by Yuli Jian, Kangkang Yang, Jinjing Li, Ling Tang, Guang Zeng, Xiaoxin Sun, Xiao Yu, Abdullah Al-danakh, Qiwei Chen, Deyong Yang, Shujing Wang

“…Immunohistochemistry analysis confirmed the expression patterns of ST3Gal1 and ST3Gal5 in 30 KIRC patients. …”
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Formation and Evolution Mechanisms of Severe Haze Pollution in the Sichuan Basin, Southwest China by Xianyu Yang, Yaqiong Lu, Xinsheng Zhu, Jianjun He, Qi Jiang, Kai Wu, Haolin Wang, Xiaoling Zhang, Shigong Wang

“…Our results reveal the detailed formation mechanism of a severe haze episode in the SCB under the effects of regional transport and synoptic forcing patterns to improve the understanding of haze formation in areas with complex terrain.…”
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Hydrogen bond interactions of coumarin-153 in molecular solvents: molecular dynamics and principal component analysis by Goloviznina, Kateryna, Dudariev, Dmytro, Miannay, François-Alexandre,  Kalugin, Oleg, Koverga, Volodymyr, Takamuku, Toshiyuki, Vitale, Raffaele, Idrissi, Abdenacer

“…Principal component analysis (PCA) was then performed on these distances to compare the unique structures surrounding donor bond atoms and identify patterns in the interactions between C153 and various solvent, such as acetonitrile, butyrolactone, propylene carbonate, methanol, ethanol, propanol, and butanol.Our findings demonstrate that, when C153 acts as a hydrogen bond donor, the interaction behavior of the H atoms that are close to the N atom and that of the H atom close to the trifluoromethyl F atom of C153 is substantially different. …”
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A sedimentological oxymoron: highly evolved glauconite of earliest diagenetic origin by Tribovillard, Nicolas, Bout-Roumazeilles, Viviane, Guillot, François, Baudin, François, Deconinck, Jean-François, Abraham, Romain, Ventalon, Sandra

“…Contrasted grain-size distribution patterns of glauconite and quartz grain populations (isolated after acid digestion and magnetic separation) evidenced that glauconite formed after sediment deposition. …”
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Differential expression and localization of expansins in Arabidopsis shoots: implications for cell wall dynamics and drought tolerance by Darina Balkova, Katerina Mala, Jan Hejatko, Jan Hejatko, Klara Panzarova, Lamis Abdelhakim, Barbora Pleskacova, Marketa Samalova, Marketa Samalova

“…We observed distinct expression patterns of expansins, with EXPA1 primarily localized in stomatal guard cells, while EXPA10 and EXPA15 showed strong cell wall (CW) localization in epidermal and other tissues. …”
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Ultrahigh-field imaging (7 Tesla) in DNET: Unmasking microstructural imaging characteristics – A case report by Marta Calvo-Imirizaldu, Daniele Botta, Margitta Seeck, Jan Novy, Jose Federico Ojeda Esparza, Aikaterini Fitsiori, Corrado Santarosa, Kevin Battistini, Karl-Olof Lövblad, Felix T. Kurz

“…We review the various MRI patterns of DNET, which have been shown to correlate with histological subtypes and the extent of the epileptogenic zone.Complete tumor resection is essential for long-term control and recurrence prevention, emphasizing the importance of precise preoperative visualization of the tumor and its surrounding tissue. …”
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