Swallowing-related muscle inflammation and fibrosis induced by a single dose of radiation exposure in mice by Shuntaro Soejima, Chia-Hsien Wu, Haruna Matsuse, Mariko Terakado, Shinji Okano, Tsuyoshi Inoue, Yoshihiko Kumai

“…Results Compared to control mice, those treated with 20-Gy, but not 6.7-Gy, irradiation had significantly increased tumor necrosis factor-α (TNF-α) (p < 0.01) and α-smooth muscle actin (αSMA) (p < 0.05) expression at 10 days and significantly increased expression levels of motif chemokine ligand-2 (CCL2), α-SMA, tumor growth factor-β1 (TGF-β1), type1 collagen, and interleukin-1β (IL-1β) (p < 0.05) in the muscles at 1 month by real-time PCR analysis. …”
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Promoting ER stress in a plasmacytoid dendritic cell line drives fibroblast activation by Beatriz H. Ferreira, Inês S. Silva, Andreia Mendes, Fátima Leite-Pinheiro, Adrienne W. Paton, James C. Paton, Iola F. Duarte, Philippe Pierre, Catarina R. Almeida

“…Results Direct contact of CAL-1 and IMR-90 cells under ER stress conditions led to increased expression of fibronectin and alpha-smooth muscle actin (α-SMA). This effect required expression of the ER stress signaling sensor protein kinase R-like ER kinase (PERK) in pDCs and was observed only upon direct contact between both cell types. …”
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Estimation of cytoprotective effect of bismuth tripotassium dicitrate on gastric mucosa at <i>H. pylori</i> eradication and long-term drug intake by A. V. Kononov, S. I. Mozgovoi, L. B. Rybkina, S. S. Bunova, A. G. Shimanskaya

“…Borders of a generative zone were determined by the presence of myofibroblasts surrounding glandular epithelium which were identified immunohistochemically, using smooth-muscle actin as a marker. Cells with damaged DNA were revealed by immunehistochemical detection of Р53 protein.Results. …”
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Brazilian Thoracic Association recommendations for the management of lymphangioleiomyomatosis by Bruno Guedes Baldi, Paulo Henrique Ramos Feitosa, Adalberto Sperb Rubin, Alexandre Franco Amaral, Carolina Salim Gonçalves Freitas, Cláudia Henrique da Costa, Eliane Viana Mancuzo, Ellen Caroline Toledo do Nascimento, Mariana Sponholz Araujo, Marcelo Jorge Jacó Rocha, Martina Rodrigues de Oliveira, Tatiana Senna Galvão, Pedro Paulo Teixeira e Silva Torres, Carlos Roberto Ribeiro Carvalho

“…ABSTRACT Lymphangioleiomyomatosis (LAM) is a rare disease, characterized as a low-grade neoplasm with metastatic potential that mainly affects women of reproductive age, in which there is proliferation of atypical smooth muscle cells (LAM cells) and formation of diffuse pulmonary cysts. …”
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Microplastic exposure induces HSP90α secretion and aggravates asthmatic airway remodeling via PI3K-Akt-mTOR pathway by Mingming Xu, Jiyuan Chen, Lin Gao, Shaoxi Cai, Hangming Dong

“…Then, microplastics were proved to activate PI3K-Akt-mTOR pathway by prompting airway epithelial cells secrete HSP90α and proliferation of airway smooth muscle cells(ASMCs), leading to airway narrowing and hypersensitivity. 1G6-D7 is a monoclonal antibody to HSP90, which can reverse the pulmonary inflammation infiltration, mucus production, and airway hyperresponsiveness(AHR). …”
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A note on the global existence and boundedness of an N-dimensional parabolic-elliptic predator-prey system with indirect pursuit-evasion interaction by Liu Ling

“…We investigate the two-species chemotaxis predator-prey system given by the following system: ut=Δu−χ∇⋅(u∇w)+u(λ1−μ1ur1−1+av),x∈Ω,t>0,vt=Δv+ξ∇⋅(v∇z)+v(λ2−μ2vr2−1−bu),x∈Ω,t>0,0=Δw−w+v,x∈Ω,t>0,0=Δz−z+u,x∈Ω,t>0,\left\{\begin{array}{ll}{u}_{t}=\Delta u-\chi \nabla \cdot \left(u\nabla w)+u\left({\lambda }_{1}-{\mu }_{1}{u}^{{r}_{1}-1}+av),& x\in \Omega ,\hspace{0.33em}t\gt 0,\\ {v}_{t}=\Delta v+\xi \nabla \cdot \left(v\nabla z)+v\left({\lambda }_{2}-{\mu }_{2}{v}^{{r}_{2}-1}-bu),& x\in \Omega ,\hspace{0.33em}t\gt 0,\\ 0=\Delta w-w+v,& x\in \Omega ,\hspace{0.33em}t\gt 0,\\ 0=\Delta z-z+u,& x\in \Omega ,\hspace{0.33em}t\gt 0,\end{array}\right. in a bounded domain Ω⊂RN(N≥1)\Omega \subset {{\mathbb{R}}}^{N}\left(N\ge 1) with smooth boundary, where parameters χ,ξ,λi,μi>0\chi ,\xi ,{\lambda }_{i},{\mu }_{i}\gt 0, and ri>1(i=1,2){r}_{i}\gt 1\hspace{0.33em}\left(i=1,2). …”
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Estimating avoidable burden of stillbirth attributable to greenness improvement in Iran by Yang Yuan, Fatemeh Mayvaneh, Yaqi Wang, Jixing Yang, Yunquan Zhang, Fang Shi

“…To estimate the exposure-response functions, greenness exposures were fitted as smooth terms using restricted cubic splines. Avoidable burden of stillbirth under the predefined scenarios of improved greenness was estimated through a counterfactual analysis. …”
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Making »Un Tribunal para la Constitución«: A Documentary on the Creation and First Years of the Spanish Constitutional Court (1980–1986) by Miguel Beltrán, Daniel Sarmiento

“… This article explains how, from 2012 to 2015, the authors conceived, shot and edited the film »Un Tribunal para la Constitución«, a documentary about the first years of the Constitutional Court of Spain. …”
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Aspergillus terreus variant TB21 wet biomass optimized by in-situ transesterification for biodiesel production by Rashmi K. Bed, V. Ravi Kumar, Ameeta RaviKumar

“…The process optimization revealed that wet biomass and methanol were the most significant factors and in a short reaction time period of 5 min with low methanol: wet biomass ratio (10:1) influenced FAME production Statistical optimization studies showed that TB21 exhibited a higher FAME content of 76.5 and 38.1% (w/w) from wet and dry biomass, respectively when compared to wild type (48.1 and 24.5%). …”
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Analyzing and forecasting under-5 mortality trends in Bangladesh using machine learning techniques. by Shayla Naznin, Md Jamal Uddin, Ishmam Ahmad, Ahmad Kabir

“…The forecasted rates fall short of the Sustainable Development Goal (SDG) target of 25 deaths per 1,000 live births by 2030, underscoring the need for intensified interventions in healthcare access and maternal health to achieve this target.…”
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Inhibition of the Wall-attached Fuel Combustion and the Formation of Aerosol Particle by Han Wu, Cong Liu, Longmin Tang, Chunze Cen, Sheng-Lun Lin, Chien-Er Huang

“…The entire vapor explosion process was very short, lasting about 200 milliseconds. Furthermore, the increasing WE had a negative effect on the nucleate boiling intensity when the liquid pool temperature significantly enhanced it. …”
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Treatment Patterns of Follicular Lymphoma in the United States: A Claims Analysis by Scott F. Huntington, Sreevalsa Appukkuttan, Wenyi Wang, Yuxian Du, Sari Hopson, Svetlana Babajanyan

“…The use of combination therapy decreased with each line of therapy and the numbers of patients receiving third- or fourth-line therapy were small in this study, potentially due to the short follow-up. Rituximab as monotherapy or in combination was utilized most frequently; however, the variety of other therapies used demonstrates that the standard management of FL remains unclear. …”
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Bifurcation of time crystals in driven and dissipative Rydberg atomic gas by Bang Liu, Li-Hua Zhang, Yu Ma, Qi-Feng Wang, Tian-Yu Han, Jun Zhang, Zheng-Yuan Zhang, Shi-Yao Shao, Qing Li, Han-Chao Chen, Guang-Can Guo, Dong-Sheng Ding, Bao-Sen Shi

“…Bifurcation of time crystals in strongly interacting Rydberg atoms is observed; the process manifests as a transition from a time crystal of long periodicity to a time crystal of short periodicity, or vice versa. By manipulating the driving field parameters, we observe the time crystal’s bistability and a hysteresis loop. …”
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Estimating Mortality Related to O3 and PM25 under Changing Climate and Emission in Continental Southeast Asia by Giang Tran Huong Nguyen, Thuan Thi Thanh Nguyen, Hikari Shimadera, Katsushige Uranishi, Tomohito Matsuo, Akira Kondo

“…Future emission change alone under Evaluating the Climate and Air Quality Impacts of Short-Lived Pollutants current legislation (ECLIPSE CLE) scenario induces +7113 and +11072 additional O3 and PM2.5 related mortalities, respectively. …”
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Uncertainties in the finite-time Lyapunov exponent in an ocean ensemble prediction model by M. Matuszak, J. Röhrs, P. E. Isachsen, P. E. Isachsen, M. Idžanović

“…Averaging of FTLE fields is thus effective at removing short-lived and unpredictable structures and may provide the means to employ FTLE analysis in forecasting applications that require the ability to separate uncertain from certain flow features.…”
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The Effect of Injectable Medication Procedure on the Level of Pain among Early Childhood patients by Farida A. K. Tahir, Pary M. Azize, Aram N. Abdul Razzaq

“…Facial expression was also changed to contracted face in the post procedure. Sleeping from short interval to absent sleeping was shown. Significant variation between pre and post-procedure were assessed. …”
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Small open reading frames (sORFs): Driving big improvements in plant development and quality by Kui Dong, Chaofan Shan, Dongyu Wen, Zifan Cui, Jun Cao

“…Small open reading frames (sORFs) are defined as short nucleotide sequences, typically no longer than 300 base pairs, which have the potential to encode small peptides. …”
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Structural basis for RNA-guided DNA degradation by Cas5-HNH/Cascade complex by Yanan Liu, Lin Wang, Qian Zhang, Pengyu Fu, Lingling Zhang, Ying Yu, Heng Zhang, Hongtao Zhu

“…Abstract Type I-E CRISPR (clustered regularly interspaced short palindromic repeats)–Cas (CRISPR-associated proteins) system is one of the most extensively studied RNA-guided adaptive immune systems in prokaryotes, providing defense against foreign genetic elements. …”
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Congenital Chylothorax: Case Report by Egemen Tolunay, Bulut Varlı, Fırat Tülek, Emre Pabuçcu, Şerife Esra Çetinkaya, Korhan Kahraman, Acar Koç

“…After treatment with medium-and short-chain fatty acids, octreotid, and pleural drainage newborn is discharged from the hospital well two months later. …”
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The Taking Charge After Stroke (TaCAS) study protocol: a multicentre, investigator-blinded, randomised controlled trial comparing the effect of a single Take Charge session, two Ta... by Mark Weatherall, Harry McNaughton, Vivian Wai Yin Fu

“…Participants will be randomly assigned to one Take Charge session, two Take Charge sessions 6 weeks apart or control.Outcomes The primary outcome will be the Physical Component Summary score of the Short-Form 36 at 12 months post stroke. Secondary outcomes will include dependence (modified Rankin scale), performance in activities of daily living (Barthel Index) and carer strain (Caregiver Strain Index), at 6 and 12 months post stroke. …”
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