A time to reflect as we end 2022 by Tiing Leong Ang, Mahesh Choolani, Kian Keong Poh

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Assessment of Malaysia-wide PM2.5 Forecasts from a Global Model by Zhixian Tan, Mohd Talib Latif, Matthew J. Ashfold

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The weight-adjusted-waist index predicts all-cause and cardiovascular mortality in hypertension by Yu Zheng, Zixing Nie, Yifan Zhang, Tao Sun

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Evaluation of Urban Composite Carbon Sink Value: A Case Study of Shenyang by Tiemao SHI, Di WANG, Yu TANG, Peiying LI

“…The afforestation cost method, carbon tax method, and carbon trading method are adopted to evaluate the composite carbon sink value of the research area. …”
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The Link Between Hate Speech and Terrorism: A Critical Analysis of Indonesia’s Legal Framework by Abdurrakhman Alhakim, Ampuan Situmeang, David Tan, Emiliya Febriyani

“…Hate speech and terrorism are two forms of crime that are similar in their discriminatory nature. …”
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Protocol-based set-membership state estimation for linear repetitive processes with uniform quantization: a zonotope-based approach by Minghao Gao, Pengfei Yang, Hailong Tan, Qi Li

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Healthcare and environmental sustainability by Tiing Leong Ang, Mahesh Choolani, Kian Keong Poh

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Sporoderm-Removed Spore Powder May Suppress the Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma Cells Through PI3K/AKT/mTOR and Erk Pathway by Jingyan Liu Master degree, Tao Zeng Doctor degree

“…The expressions of PI3K, AKT/p-AKT, Erk/p-Erk, JNK1, and mTOR were detected by Western blotting. We found that the MCP-1 protein was highly expressed in KYSE140 and KYSE510. …”
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Machine learning-random forest model was used to construct gene signature associated with cuproptosis to predict the prognosis of gastric cancer by Xiaolong Liu, Pengxian Tao, He Su, Yulan Li

“…GSEA and GSVA results indicated that high risk patients with GC were mainly associated with the enrichment of ANGIOGENESIS and TGF_BETA_SIGNALING pathways. Finally, EFNA4 expression in GC was significantly higher than that in normal tissues, and patients with GC and high EFNA4 expression exhibited improved prognosis. …”
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Spatial-Temporal Variations and Influencing Factors of Water-related Ecosystem Services in Southwest China Under Complex Terrain by TANG Shuang, ZHU Chongjing, GAO Jie, BIAN Hongyan

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Causal Effects of PM2.5, NOx, and NO2 on Cognitive Function: A Two-sample Mendelian Randomization Study by Yilin Tang, Zhenyu Li, Yicheng Fu, Mingyi Zhao

“…Abstract Epidemiological studies have revealed that air pollutants are related to cognitive decline, but a causal relationship has not been established. We conducted a two-sample Mendelian randomization (MR) study using pooled statistics from publicly available genome-wide association study (GWAS) data to show the association between air pollutants and cognitive decline in the European population. …”
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Editorial: The loss and acceleration mechanisms of energetic electrons in the Earth’s outer radiation belt by Chaoling Tang, Zheng Xiang, Hong Zhao, Xu Liu

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Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis by Yuan Liu, Wacili Da, Ming-Jie Xu, Chao-Xin Xiao, Tao Deng, Sheng-Liang Zhou, Xiao-Ting Chen, Yao-Jia Zhou, Li Tang, Yong Nie, Yi Zeng, Hui-Qi Xie, Bin Shen

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L-arabinose alleviates constipation through gastrointestinal peptide，gut microbiota，and Phlpp2 of gastrointestinal rhythms in rats by Ting Gong, Linzheng Liao, Yong Tang, Weiwei Liu, Ling Yao, Zhen Wu, Jianmei Li, Fulai Bai, Qian Zhang, Liling Tang

“…This study investigated the effects of L-arabinose in constipated rat at doses of 400, 600, and 800 mg/kg body weight (B.W.). The 800 mg/kg B.W. dose significantly improved overall physiological state, stool consistency, intestinal transit, and gastric emptying. …”
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Development and functional validation of a disulfidoptosis-related gene prognostic model for lung adenocarcinoma based on bioinformatics and experimental validation by Tao Shen, Tao Shen, Zhuming Lu, Sisi Yang, Dongxi Zhang, Yongwen Ke, Zhuowen Chen, Jinqiang Wu, Jinqiang Wu, Weidong Wu

“…Key DRGs were selected for Cox and LASSO regression to develop a prognostic model. Tensin4 (TNS4), a key gene in the model, was further evaluated through immunohistochemistry (IHC) in LUAD and normal tissues and gene knockdown experiments in vitro.ResultsTwo clusters were identified, with 225 differentially expressed genes. …”
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Identification and Analysis of Key Immune- and Inflammation-Related Genes in Idiopathic Pulmonary Fibrosis by Tan Y, Qian B, Ma Q, Xiang K, Wang S

“…Real-time quantitative polymerase chain reaction (RT-qPCR) results were consistent with the training and validation sets, and the expression of these key genes was significantly upregulated in the IPF samples.Conclusion: This study identified three key genes (RNASE3, S100A12 and S100A8) associated with immune response and inflammation in IPF, providing valuable insights into the diagnosis and treatment of IPF.Summary: This study focuses on cutting-edge research in IPF, with special attention to the development dynamics and application potential of IPF. …”
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Alligatorweed flea beetle Agasicles hygrophila Selman and Vogt (Coleoptera: Chrysomelidae: Halticinae) by Ted D. Center, James P. Cuda, Michael J. Grodowitz

“…EENY462, a 4-page illustrated fact sheet by Ted D. Center, James P. Cuda, and Michael J. Grodowitz, is part of the Featured Creatures collection. …”
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Alligatorweed thrips (suggested) Amynothrips andersoni O'Neill (Insecta: Thysanoptera: Phlaeothripidae) by Ted D. Center, James P. Cuda, Michael J. Grodowitz

“…EENY-476, a 3-page illustrated fact sheet by Ted D. Center, James P. Cuda, and Michael J. Grodowitz, is part of the Featured Creatures collection. …”
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Work-related musculoskeletal disorders, fatigue and stress among gas station workers in China: a cross-sectional study by Jing Wang, Andrew Paul Smith, Jialin Fan, Xiaotong Tan

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Mpox clade I outbreak: how should Asia prepare and respond? by Poh Lian Lim, Wilnard Yeong Tze Tan, Shawn Vasoo

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