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  1. 841

    Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy by Xia Liu, Emily Shaw, Fusheng Si, Guangyong Peng, Yan Tao, Feiya Ma, David Bagley, Yuanqin Zhang

    Published 2022-10-01
    “…It is now recognized that T cell functional state in the tumor microenvironment (TME) is a key determinant for effective antitumor immunity and immunotherapy. …”
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  5. 845

    Geological characteristics and main enrichment controlling factors of coalbed methane in Nanchuan area, southeastern Sichuan Basin by Xipeng HE, Kaiming WANG, Wei LUO, Yuqiao GAO, Nana LIU, Tao GUO, Yatong ZHOU, Didi WU

    Published 2025-01-01
    “…To identify the main geological factors controlling its enrichment, this study used data from drilling, cores, well logging, and experimental analyses to investigate the geological characteristics and main controlling factors for CBM enrichment, focusing on coal seam distribution, coal quality, physical properties, gas content, and fracturability characteristics of the Longtan Formation. …”
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  6. 846
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    The Modulation of Meteorological Parameters on Surface PM2.5 and O3 Concentrations in Guangzhou, China by Qiaoli Bu, Yingying Hong, Haobo Tan, Li Liu, Chunlin Wang, Jianjun Zhu, Pakwai Chan, Chen Chen

    Published 2020-07-01
    “…Abstract PM2.5 and ozone (O3) are two major pollutants that are worsening air quality in China. …”
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    Evaluation method and application for in-situ stress in No. 8+9 coal seam, southern Shenfu block, northeastern margin of Ordos Basin by Jiawei WU, Wei TANG, Yanhe ZHU, Cunwu WANG, Yongjing TIAN, Jingyu ZI, Jianghao YANG, Xian SHI

    Published 2025-01-01
    “…This study focused on the direction and magnitude of the current in-situ stress in the No. 8+9 coal seam in the southern Shenfu block, northeastern margin of the Ordos Basin. Array acoustic logging, microseismic monitoring, and imaging logging were used to evaluate the direction of the present maximum horizontal principal stress in the coal seam and its roof and floor. …”
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    Soil warming increases the active antibiotic resistome in the gut of invasive giant African snails by Yiyue Zhang, Hong-Zhe Li, Martin Breed, Zhonghui Tang, Li Cui, Yong-Guan Zhu, Xin Sun

    Published 2025-02-01
    “…Furthermore, we identified elevated biosynthetic gene clusters (BGCs) within these ARG-carrying MAGs, with a third encoding at least one BGC. …”
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  15. 855

    Impact of high-speed shear homogenization pretreatment on structure, functional characteristics, and interfacial properties: A case of Rice Glutelin by Zhuangpeng Wang, Zhangtao Chen, Lufan Tan, Jin Tu, Yong Sun, Yuanping Ye, Senwang Zhang, Leiyan Wu

    Published 2025-01-01
    “…These alterations resulted in variations in the functional and interfacial properties of RG. After HSSH treatment at 12,000 rpm for 2 min, RG exhibited optimal improvements in solubility (5.56 %), WHC (6.00 g/g) and OHC (2.20 g/g), EAI (10.19 m2/g) and ESI (341.98 min), as well as FC (16.20 %) and FS (64.21 %). …”
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  16. 856

    Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma by Liyun Gao, Jiaxin Gao, Jiayin He, Wenyan Fan, Xiangxin Che, Xin Wang, Tao Wang, Chunhua Han

    Published 2025-02-01
    “…Cluster1 showed higher levels of immune infiltration and TMB compared to cluster2. WGCNA identified 15 genes closely associated with WTAP/ZC3H13 expression and immune scores, notably CTLA4, CD27, ICOS, and LAG3. …”
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    Astaxanthin relieves HT22 cells from LPS-induced inflammation and apoptosis by inhibiting oxygen species and regulating the TLR4/MyD88/NFκB signaling pathway by Tan Wang, Rongrong Li, Ping Niu, Zhen Wei, Donge Xie, Huorong Huang, Jiayao Pan, Chunshu Rong

    Published 2025-02-01
    “…We treated HT22 cells with lipopolysaccharide (LPS), astaxanthin (ATX), and the TLR4 inhibitor TAK-242, employing CCK-8 assays, flow cytometry, and Western blotting to assess cell survival, oxidative stress, inflammation, and apoptosis. …”
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