Utilizing kombucha culture for coffee fermentation and biochemical characteristic analysis by Hayeong Kim, Jihyeon Jeon, Jiyeon Lee, Chaeri Song, Boncheol Gu, Nahyun Mariah Kim, Tae-hui Yang, Sejin Oh, Soochul Park, Kunal Pal, Ghahyun Jeffrey Kim, Doman Kim

“…As consumer interest in coffee flavour and quality continues to grow, this study aims to enhance the bioactive compounds, functionality, and sensory properties of Arabica coffee (Coffea arabica) by fermentation with black tea kombucha (K-coffee) and coffee kombucha (CK-coffee). …”
Get full text

Diagnostic ultrasound enhances, then reduces, exogenously induced brain activity of mice by Henry Tan, Devon J. Griggs, Devon J. Griggs, Lucas Chen, Kahte Adele Culevski, Kathryn Floerchinger, Alissa Phutirat, Gabe Koh, Nels Schimek, Pierre D. Mourad, Pierre D. Mourad

Get full text

Characterizing PM2.5 Secondary Aerosols via a Fusion Strategy of Two-stage Positive Matrix Factorization and Robust Regression by Chun-Sheng Huang, Ho-Tang Liao, Chia-Yang Chen, Li-Hao Young, Ta-Chih Hsiao, Tsung-I Chou, Jyun-Min Chang, Kuan-Lin Lai, Chang-Fu Wu

“…The results from the fusion model showed that the majority of secondary aerosols (sum of secondary aerosol-related species = 2.67 µg m−3) within three hours were mainly contributed by oil combustion, while the largest contributor of secondary aerosols (1.65 µg m−3) over 24 hours was industry, highlighting the need for regulation of these two sources based on various temporal scales. …”
Get full text

Circulating tumor DNA for surveillance in high-risk melanoma patients: a study protocol by Magnús P.B. Obinah, Sarah A. Al-Halafi, Karin Dreisig, Tim S. Poulsen, Christoffer Johansen, Thomas Litman, Stig E. Bojesen, Estrid Høgdall, Annette H. Chakera, Lisbet R. Hölmich

“…Circulating tumor DNA (ctDNA) is a promising biomarker that may indicate disease progression earlier than traditional surveillance methods, including 18F-FDG PET-CT, ultrasound, and clinical examination. …”
Get full text

Molecular characterization of Pseudomyxoma peritonei with single-cell and bulk RNA sequencing by Ye Jin Ha, Seong-Hwan Park, Seon-Kyu Kim, Ka Hee Tak, Jeong-Hwan Kim, Chan Wook Kim, Yong Sik Yoon, Seon-Young Kim, Jong Lyul Lee

“…We also offer protein expression data from a tissue microarray (TMA) analysis of 90 samples (45 PMPs). Our single-cell and bulk transcriptomic profiles, along with TMA verifications, reveal the cellular diversity of PMP, highlighting the coexistence of epithelial and mesenchymal characteristics within PMP cells. …”
Get full text

Dihydroquercetin attenuated Prevotella copri-caused intestinal injury by modulating gut microbiota and bile acids in weaned piglets by Long Wang, Ruizhi Hu, Siqi Ma, Xizi Yang, Jiatai Gong, Hongkun Xiang, Mingkun Shi, Xupeng Yuan, Liang Chen, Hongfu Zhang, Bie Tan, Xi He, Jianhua He, Shusong Wu

“…The piglets were the following diets for 28 d: 1) a basal diet, 2) basal diet containing 1.0 × 108 CFU/kg P. copri, 3) basal diet supplemented with 1.0 × 108 CFU/kg P. copri and 100 mg/kg DHQ. …”
Get full text

Baseline atherogenic index of plasma and its trajectory predict onset of type 2 diabetes in a health screened adult population: a large longitudinal study by Yongbing Sun, Xinbei Lin, Zhi Zou, Caiwen Zhao, Ao Liu, Jing Zhou, Zhonglin Li, Xiaoling Wu, Shewei Dou, Jiadong Zhu, Tao Li, Xue Lv, Yong Wang, Yongli Li

“…AIP was calculated as the logarithm of the ratio of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-C). …”
Get full text

Advancements in noninvasive techniques for transplant rejection: from biomarker detection to molecular imaging by Yuan Song, Yihui Wang, Wenyuan Wang, Yuji Xie, Junmin Zhang, Jing Liu, Qiaofeng Jin, Wenqian Wu, He Li, Jing Wang, Li Zhang, Yali Yang, Tang Gao, Mingxing Xie

Get full text

Watershed: a more efficient sampling unit for mountain camera traps by Jun-Jie Li, Yi-Hao Fang, Ji-Cong Zhan, Xue-Jun Yang, Can-Bin Huang, Yan-Peng Li, Kun Tan, Zhi-Pang Huang, Liang-Wei Cui, Wen Xiao

“…Abstract Wildlife camera trap (CT) surveys typically employ two-dimensional equal-area grid sampling, which often neglects the influence of complex mountainous terrain on species distribution, potentially yielding misleading outcomes. …”
Get full text

Cross-protection against homo and heterologous influenza viruses via intranasal administration of an HA chimeric multiepitope nanoparticle vaccine by Yongqiang Zhao, Jia Liu, Chun Peng, Shuangshuang Guo, Bo Wang, Longping Chen, Yating Wang, Haiwen Tang, Liming Liu, Qi Pan, Shiren Li, Jingyu Wang, Dongni Yang, Enqi Du

“…When CHM-f nanoparticles adjuvanted with CpG IAMA-002, the weight loss protective effect, cellular immune responses and mucosal IgA responses were significantly augmented. …”
Get full text

Adipose tissue-derived microRNA-450a-5p induces type 2 diabetes mellitus by downregulating DUSP10 by Jiaojiao Zhu, Yanting Hou, Wei Yu, Jingzhou Wang, Xiaolong Chu, Xueting Zhang, Huai Pang, Dingling Ma, Yihan Tang, Menghuan Li, Chenggang Yuan, Jianxin Xie, Cuizhe Wang, Jun Zhang

Get full text

Use of Anabolic-Androgenic Steroids and Male Fertility: A Systematic Review and Meta-analysis by Prashant Motiram Mulawkar, Pankaj N. Maheshwari, Vineet Gauhar, Sumeet Gopal Agrawal, Taofiq Olayinka Mohammed, Abhishek Gajendra Singh, Gopal Ramdas Tak, Utsav Shailesh Shah, Deepali Parthsarthi Shukla, Deepali Mamankar

“…The total testosterone (TT) levels were comparable in users and naïve populations at baseline, 3 months and 6 months after stopping, but at 1 year, TT values were lower in AAS users. …”
Get full text

Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer by Xingsheng Liu, Kun Qian, Lei Su, Xiaoru Tian, Xin Zhao, Tengteng Wang, Li Han, Zhenzhen Li, Peilong Zhang, Ruotian Wang, Baodong Liu, Yuanbo Li, Xiaogang Tan, Yi Zhang

“…Results For the 53 nodule samples from 26 MPLCs patients, EGFR was the mostly mutated genes, and the TP53 mutation frequency was notably different between major and minor nodules. …”
Get full text

A generative whole-brain segmentation model for positron emission tomography images by Wenbo Li, Zhenxing Huang, Hongyan Tang, Yaping Wu, Yunlong Gao, Jing Qin, Jianmin Yuan, Yang Yang, Yan Zhang, Na Zhang, Hairong Zheng, Dong Liang, Meiyun Wang, Zhanli Hu

“…Methods In this study, we propose a generative multi-object segmentation model for brain PET images with two learning protocols. First, we pretrained a latent mapping model to learn the mapping relationship between PET and MR images so that we could extract anatomical information of the brain. …”
Get full text

Screen of propionate-producing probiotic strains in attenuating murine colitis by modulating immune response and restoring the intestinal barrier by Ting Shu, Xizi Song, Silu Zhang, Xiaoli Zhou, Zhizhu Zhang, Pengfei Wang, Hu Canying, Jie Pan, Xiaoshuang Dai, Yan Tan, Wu Xiyang, Huicui Meng, Guoxun Xiao, Huaijie Hao

Get full text

Self-driving lab for the photochemical synthesis of plasmonic nanoparticles with targeted structural and optical properties by Tianyi Wu, Sina Kheiri, Riley J. Hickman, Huachen Tao, Tony C. Wu, Zhi-Bo Yang, Xin Ge, Wei Zhang, Milad Abolhasani, Kun Liu, Alan Aspuru-Guzik, Eugenia Kumacheva

Get full text

A global open-source dataset of monthly irrigated and rainfed cropped areas (MIRCA-OS) for the 21st century by Endalkachew Abebe Kebede, Kevin Ong’are Oluoch, Stefan Siebert, Piyush Mehta, Sarah Hartman, Jonas Jägermeyr, Deepak Ray, Tariq Ali, Kate A. Brauman, Qinyu Deng, Wei Xie, Kyle Frankel Davis

Get full text

Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure by Sophie Shen, Tessa Werner, Samuel W. Lukowski, Stacey Andersen, Yuliangzi Sun, Woo Jun Shim, Dalia Mizikovsky, Sakurako Kobayashi, Jennifer Outhwaite, Han Sheng Chiu, Xiaoli Chen, Gavin Chapman, Ella M. M. A. Martin, Di Xia, Duy Pham, Zezhuo Su, Daniel Kim, Pengyi Yang, Men Chee Tan, Enakshi Sinniah, Qiongyi Zhao, Sumedha Negi, Meredith A. Redd, Joseph E. Powell, Sally L. Dunwoodie, Patrick P. L. Tam, Mikael Bodén, Joshua W. K. Ho, Quan Nguyen, Nathan J. Palpant

Get full text

Subwavelength-scale off-axis optical nanomanipulation within Gaussian-beam traps by Zhou Lei-Ming, Sun Wan, Tao Zong-Qiang, Xiong Ning-Jun, Huang Chan, Jiang Xiao-Yun, Ren Yu-Xuan, Yang Yuanjie, Shi Yu-Zhi, Hu Ji-Gang, Zhan Qiwen

Get full text

Perceptions of healthcare workers in high-risk areas of a Singapore hospital during COVID-19: a cross-sectional study by Phui-Sze Angie Au-Yong, Wee-Ming Peh, Frederick Hong-Xiang Koh, Li-Ming Teo, Siok-Peng Ng, Alina Li-Na Tan, Aven Shan-Hua Ng, Min-Hoe Chew

Get full text