Promoções de Pacotes de Gratificações: Percepção dos Gerentes de Controladoria e dos Gerentes Comerciais by Reinaldo Guerreiro, Beng Soo Ong, Ariovaldo dos Santos

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Differences in Metabolites of Different Varieties from Xinjiang Large-fruit Sea Buckthorn as Analyzed by Non-targeted Metabolomics by Rong HAN, Yan MA, Shengjie LI, Xintao MENG, Mingqiang XU, Ting ZHANG, Yan PAN

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Editorial: Ovarian cancer targeted medication: PARP inhibitors, anti-angiogenic drugs, immunotherapy, and more, volume II by Zhi-Bin Wang, Zhi-Bin Wang, Zhi-Bin Wang, De-Hua Liao, Guang Lei, Zhao-Qian Liu, Zhao-Qian Liu, Nayiyuan Wu, Nayiyuan Wu, Jing Wang, Jing Wang

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Quitándonos los tapones: El Entrenamiento Fonológico L2 y sus Efectos en la Percepción by Deida Perea Irigoyen, Sussan U. Roo y Sánchez, Alberto Escalera Narváez

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Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers by Hengyan Zhang, Ye Zhou, Heguo Yan, Changxing Huang, Licong Yang, Yangwen Liu

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MONITORING OF THE NOISE LEVEL GENERATED WHEN THE MILLING OF REINFORCED CONCRETE PREFABRICATES AT MACOFIL S.A. TÂRGU JIU by Emil Catalin SCHIOPU, Madalina DRACEA

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Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain by Chae-Jeong Lee, Seung Hyun Jang, Jiwoo Lim, Hyunju Park, So-Hee Ahn, Seon Young Park, Hyangmi Seo, Soo-Jin Song, Jung-A Shin, Chulhee Choi, Heon Yung Gee, Youn-Hee Choi

“…Single-cell RNA sequencing revealed that these anti-inflammatory exosomes targeted macrophages and microglia, reducing the expression of inflammation-related genes. …”
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Eine Normativität des Imperiums und eine andere des Marktes am Río de la Plata? by Gilberto Guerra Pedrosa

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Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis by Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Ali S. Alzahrani, Yufei Shi

“…Mertk, a member of the TAM (Tyro, Axl, Mertk) family of RTKs, was also overexpressed in Met cells, which led to increased MAPK activation, epithelial–mesenchymal transition (EMT), and enrichment of cancer stem cells. …”
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Golden Tandem of Photothermal Ablation and Simultaneous Anti-Inflammation in One Nanoparticle for Activated Macrophage-Targeted Atherosclerosis Treatment by Lu Y, Wang Y, Li Y, Li Y, Jiang YW, Li J

“…The preparation and characterization of GSNPD, their cellular toxicity, photothermal conversion and targeted ablation efficiency, anti-inflammation and ROS scavenging effect, as well as the inhibition of foam cell formation were studied in vitro.Results: The experimental results showed that the fabricated GSNPD NPs displayed positive effects on anti-atherosclerosis by pro-inflammatory macrophages ablation, NO production and ROS scavenging.Discussion: GSNPD NPs were designed to effectively and accurately ablate pro-inflammatory macrophages by recognizing and targeting to SR-A overexpressed on the activated macrophages of arterial plaques via PTT, and simultaneous inhibit the PTT-induced inflammation through the laser-activated NO release in situ. …”
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Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi by Mireia Larrosa-Godall, Joshua X. D. Ang, Philip T. Leftwich, Estela Gonzalez, Lewis Shackleford, Katherine Nevard, Rob Noad, Michelle A. E. Anderson, Luke Alphey

“…Separately a transgenic line which expresses a gRNA targeting the female specific exon of dsx was inserted into that same target site. …”
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LISTENING AND SPEAKING SKILLS AS LEARNING AND TARGET NEEDS IN BUSINESS ENGLISH PROGRAM FOR TOUR GUIDE DIPLOMA STUDENTS IN KENYA. by Douglas Ondara Orang'i

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Exploring the interactions of rapamycin with target receptors in A549 cancer cells: insights from molecular docking analysis by Sanjeev K. Ganesh, C. Subathra Devi

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New insights from an enhancement of hydrogeological archives of a French karst watershed over the last 50 years by Labat, David, Guilloteau, Thomas, Lamagnère, Sébastien, Dumareau, Thaïs, Haryouli, Gabin, Béranger, Sandra, Granouillac, Franck, Sivelle, Vianney

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Targeting cryptic allosteric sites of G protein-coupled receptors as a novel strategy for biased drug discovery by Xin Qiao, Xiaolong Li, Mingyang Zhang, Ning Liu, Yanmei Wu, Shaoyong Lu, Ting Chen

“…Biased signaling allows for the specific activation of certain pathways from the full range of receptors’ signaling capabilities. Targeting more variable allosteric sites, which are spatially different from the highly conserved orthosteric sites, represents a novel approach in biased GPCR drug discovery, leading to innovative strategies for targeting GPCRs. …”
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Dual-targeting CAR T cells for B-cell acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma by Gustavo de Oliveira Canedo, Claire Roddie, Persis J. Amrolia

“…This review summarizes the state of the art with dual-targeting CAR T cells for B-cell ALL and B-NHL, the challenges encountered, and possible next steps to overcome them.…”
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Superación profesional del especialista en Ginecología y Obstetricia para el modelo de parto humanizado by Ariané Dopazo-Companioni

“…Se constataron insuficiencias en el desempeño delespecialista en Ginecología y Obstetricia, así como críticas sobre la atención, en esa institución,al parto humanizado, que revelan necesidades superación profesional.…”
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EFECTOS CATEGORIALES EN TAREAS DE DENOMINACIÓN Y CATEGORIZACIÓN DE DIBUJOS CON Y SIN COLOR by Macarena Martínez-Cuitiño, Agustina Peccina, Federico Soriano, Juan Pablo Barreyro

“…La Hipótesis Pre-Semántica de los Efectos Categoriales (PACE) propone que los SV y OI se verán favorecidos/desfavorecidos en función de las demandas perceptuales de cada tarea que se administre. El objetivo de este trabajo es indagar posibles EC en tareas de denominación y categorización utilizando tanto dibujos en blanco y negro como a color. …”
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Mini meta-analysis of anticholinesterase actions of atorvastatin, simvastatin and rosuvastatin, and in silico identification of their protein targets in Mus musculus by Fouad Kasim Mohammad, Rawnaq Faris Al-Shalchi

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Medicalização do parto: a apropriação dos processos reprodutivos femininos como causa da violência obstétrica by Kenia Martins Pimenta Fernandes, Carlos Mendes Rosa

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