Optimization of bioactive compounds and sensory quality in thermosonicated black carrot juice: A study using response surface methodology, gradient boosting, and fuzzy logic by Seydi Yıkmış, Melikenur Türkol, Ishak Pacal, Aylin Duman Altan, Nazlı Tokatlı, Gholamreza Abdi, Nazan Tokatlı Demirok, Rana Muhammad Aadil

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Targeting eEF1A reprograms translation and uncovers broad-spectrum antivirals against cap or m6A protein synthesis routes by Elisa Molina Molina, Joan Josep Bech-Serra, Eloi Franco-Trepat, Ignasi Jarne, Daniel Perez-Zsolt, Roger Badia, Eva Riveira-Muñoz, Edurne Garcia-Vidal, Lluís Revilla, Sandra Franco, Ferran Tarrés-Freixas, Núria Roca, Gerardo Ceada, Karl Kochanowski, Dàlia Raïch-Regué, Itziar Erkizia, Rytis Boreika, Antoni E. Bordoy, Laia Soler, Sonia Guil, Jorge Carrillo, Julià Blanco, Miguel Ángel Martínez, Roger Paredes, Alejandro Losada, Pablo Aviles, Carmen Cuevas, Júlia Vergara-Alert, Joaquim Segalés, Bonaventura Clotet, Ester Ballana, Carolina de la Torre, Nuria Izquierdo-Useros

“…Yet, it fails to inhibit retroviruses that exploit m6A synthesis routes and are blocked by drugs targeting IGF2BP2 m6A reader. By deciphering the molecular fingerprint of cells treated with therapies targeting translation we identify a rational approach to select broad-spectrum antivirals with potential to counteract future pandemic viruses.…”
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Targeting transforming growth factor-β1 by methylseleninic acid/seleno-L-methionine in clear cell renal cell carcinoma: Mechanisms and therapeutic potential by Aseel O. Rataan, Yan Xu, Sean M. Geary, Yousef Zakharia, Eman S. Kamel, Youcef M. Rustum, Aliasger K. Salem

“…Major clinical challenges to current ccRCC treatments include high drug-resistance rates as well as dose-limiting adverse events; underlining the need to identify additional ‘druggable’ targets. TGF-β1, VEGF, and PD-L1 are potential therapeutic targets in ccRCC. …”
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Efektifitas Serbuk Daun Tagetes erecta Linnaeus untuk Mengendalikan Nematoda Bengkak Akar (Meloidogyne spp.) pada Tanaman Tomat (Lycopersicum esculentum Mill.) by Okiel Trismal, Munzir Busniah, Winarto Winarto

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Real-world pharmacovigilance analysis unveils the toxicity profile of amivantamab targeting EGFR exon 20 insertion mutations in non-small cell lung cancer by Jing Zhang, Wenjie Li

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AN EFFECTIVE APPROACH TO FACE RECOGNITION WITH ARTIFICIAL INTELLIGENCE AND THE INTERNET OF THINGS USING NVIDIA JETSON NANO by Ngoc Giau Pham, Nhien Loc Bui, Quang Hien Tran, Le Thanh Hai Tong, Hong Ngoc Tran

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Effect of nirmatrelvir/ritonavir (Paxlovid) on hospitalization among adults with COVID-19: An electronic health record-based target trial emulation from N3C. by Abhishek Bhatia, Alexander J Preiss, Xuya Xiao, M Daniel Brannock, G Caleb Alexander, Robert F Chew, Hannah Davis, Megan Fitzgerald, Elaine Hill, Elizabeth P Kelly, Hemalkumar B Mehta, Charisse Madlock-Brown, Kenneth J Wilkins, Christopher G Chute, Melissa Haendel, Richard Moffitt, Emily R Pfaff, N3C Consortium

“…<h4>Methods and findings</h4>This target trial emulation used a cohort of 703,647 patients with COVID-19 seen at 34 clinical sites across the United States between April 1, 2022 and August 28, 2023. …”
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Tarea de entrenamiento de inhibición de la respuesta para niños escolares: diseño, implementación y análisis de transferencia. Un estudio piloto. by Yesica Aydmune, Sebastián Lipina, Isabel Introzzi

“…Por eso, este estudio se propuso diseñar, implementar y evaluar la eficacia de una tarea de entrenamiento de inhibición de la respuesta en niños de 6 y 7 años de edad. …”
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Efektivitas Peraturan Presiden Nomor 17 Tahun 2019 tentang Pengadaan Barang dan Jasa Pemerintah untuk Percepatan Pembangunan Kesejahteraan di Papua Barat by Oktovianus Mirino, Henrikus Renjaan, Yusty F. Rahawarin

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Smartphone-Based Intervention Targeting Norms and Risk Perception Among University Students with Unhealthy Alcohol Use: Secondary Mediation Analysis of a Randomized Controlled Trial by Joseph Studer, John A Cunningham, Elodie Schmutz, Jacques Gaume, Angéline Adam, Jean-Bernard Daeppen, Nicolas Bertholet

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Culture-independent detection of Mycobacterium tuberculosis complex DNA using targeted next generation sequencing in African buffalo (Syncerus caffer) oronasal swabs in South Africa by Sinegugu Kholeka Mhlophe, Charlene Clarke, Giovanni Ghielmetti, Giovanni Ghielmetti, Megan Matthews, Tanya Jane Kerr, Michele Ann Miller, Wynand Johan Goosen, Wynand Johan Goosen

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Quantitative descriptive analysis, non-targeted metabolomics and molecular docking reveal the dynamic aging and taste formation mechanism in raw Pu-erh tea during the storage by Bingsong Ma, Cunqiang Ma, Binxing Zhou, Xuan Chen, Yuhua Wang, Yifan Li, Junfeng Yin, Xinghui Li

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Comparative effectiveness of laparoscopic versus open colectomy in colon cancer patients: a study protocol for emulating a target trial using cancer registry data by Semaw Ferede Abera, Gabriele Robers, Anika Kästner, Ulrike Stentzel, Kerstin Weitmann, Wolfgang Hoffmann

Subjects: “…Target trial emulation…”
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Phytoconstituents of Hericium erinaceus Exert Benefits for ADHD Conditions by Targeting SLC6A4: Extraction, Spectroscopic Characterization, Phytochemical Screening, In Vitro, and Computational Perspectives by Kamalaharshini Mohan, Nandhakumar Ravichandran, Harish Rajendran, Jency Roshni, Mahema Sivakumar, Janakiraman Velayudam, Sheikh F. Ahmad, Haneen A. Al-Mazroua, Shiek SSJ Ahmed

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Inhaling arsenic aggravates airway hyperreactivity by upregulating PNEC-sourced 5-HT in OVA-induced allergic asthma by Xue Lu, Zhu-Xia Tan, Ya-Xin Yao, Ze-Yan Li, Yan-Yan Zhu, Qian-Qun Yang, Zhao Li, Kun Peng, Yan Wang, De-Xiang Xu

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Dietary tea tree (Melaleucae Aetheroleum) oil fortifies growth, biochemical, immune-antioxidant trait, gene function, tissue reaction, and Aeromonas sobria resistance in Nile tilapia (Oreochromis niloticus) by Mohamed Shaalan, Heba H. Mahboub, Ahmed Hosny Abdelgawad, Abdelwahab A. Abdelwarith, Elsayed M. Younis, Ahmed A. Elnegiry, Asmaa W. Basher, Walaa El-Houseiny, Sherif M. Shawky, Sahar H. Orabi, Simon J. Davies, Yasmina K. Mahmoud

Subjects: “…Growth trait…”
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Robustness and limitations of maximum entropy in plant community assembly by Jelyn Gerkema, Daniel E. Bunker, Andrew M. Cunliffe, Erika Bazzato, Michela Marignani, Tommaso Sitzia, Isabelle Aubin, Stefano Chelli, Julieta A. Rosell, Peter Poschlod, Josep Penuelas, Arildo S. Dias, Christian Rossi, Tanvir A. Shovon, Juan A. Campos, Mark C. Vanderwel, Sharif A. Mukul, Bruno E.L. Cerabolini, Thomas Sibret, Bruno Hérault, Sylvain Schmitt, Pedro Higuchi, James L. Tsakalos, Decky I. Junaedi, Yun-Peng Zhao, Vanessa Minden, Ana Carolina da Silva, Tereza Mašková, Roberto Canullo, Ning Dong, Edwin T. Pos

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Management of a Female Patient with Irritable Bowel Syndrome and Somatoform Disorder by E. A. Trush, E. A. Poluektova, A. G. Beniashvili, O. S. Shifrin

Subjects: “…functional diseases of the gastrointestinal tract…”
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