Fatty Acids of Erythrocyte Membranes and Blood Serum as Possible Predictors of Exacerbation in Patients with Inflammatory Bowel Diseases by M. V. Kruchinina, M. F. Osipenko, A. I. Valuyskikh, E. Yu. Valuiskikh, I. O. Svetlova

“…The study of the composition of fatty acids (FAs) in the membranes of erythrocytes and blood serum was carried out using a gas chromatograph mass spectrometry system based on three quadrupoles Agilent 7000B (Agilent Technologies Inc., USA).Results. In the acute stage, patients with IBD have a higher total content of saturated fatty acids (SFAs) in erythrocyte membranes compared to the control group (p = 0.006), and, on the contrary, lower levels of unsaturated fatty acids (UFAs) (p = 0.005), mainly due to polyunsaturated FAs (PUFAs) (p = 0.026), namely omega-6 PUFAs (p = 0.011).Remission of IBD is associated with an increase in the level of a number of SFAs in the blood serum — margaric C17:0 (p = 0.024), arachidic acid (C20:0) — in erythrocyte membranes and serum (p = 0.0001 and p = 0.019, respectively), with a decrease in the total content of monounsaturated FAs in erythrocyte membranes (p = 0.022), an increase in the total concentration of PUFAs due to both omega-3 PUFAs (p = 0.0008) and omega-6 PUFAs (p = 0.033) in erythrocyte membranes compared with a group of healthy individuals.The exacerbation stage in patients with IBD examined over time is associated with higher levels of stearic FA C18:0 (p = 0.005), SFA/UFA (p = 0.034) and SFA/PUFA (p = 0.039) ratios in erythrocyte membranes, serum level of arachidic FA C20:0 (p = 0.008), and, on the contrary, lower content of UFAs in erythrocyte membranes — eicosapentaenoic C20:5n-3 (p = 0.0023), eicosadienoic C20:2n-6 (p = 0.0027), hexadecadienoic C16:2n-6 (p = 0.006), docosatetraenoic C22:4n-6 (p = 0.008) and alpha-linolenic C18:3n-3 (p = 0.039).A combined “panel” of fatty acids, including the levels of C20:2n-6, C18:0 in erythrocyte membranes and the content of C20:0 in blood serum, provided an AUC of 0.683 (95 % CI: 0.500–0.844), sensitivity 91.4 %, specificity 68.3 %.Levels of C20:5n-3, C20:2n-6, C18:0, C16:2n-6, C22:4n-6, C18:3n-3 fatty acids, SFA/UFA and SFA/PUFA ratios in erythrocyte membranes and content C20:0 in blood serum, used as biomarkers — predictors of the development of exacerbation in patients with IBD who were in remission, predicted the development of exacerbation of IBD after 2–4 months in the case of maximally changed levels of FAs, after 6–8 months — with moderately changed levels FAs, maintaining remission for 12 months — with minimally changed FAs levels.Conclusion. …”
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Spatiotemporal analysis of ecosystem services and the impact of new-type urbanization: A case study of Chengdu, China by Pinjian Li, Tianhong Li

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Gradient pooling distillation network for lightweight single image super-resolution reconstruction by Zhiyong Hong, GuanJie Liang, Liping Xiong

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Numerical Study of a Supersonic Nozzle Gas Jet Laden with a Dry Powder Fire-extinguishing Agent Injected from a Bypass Injector by L. Zhang, S. Wu, Y. Feng, H. Guan

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Editorial: Drug repurposing for cancer treatment: current and future directions by Marios Lampros, Nikolaos Vlachos, Georgios D. Lianos, Christina Bali, George A. Alexiou

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Secure Pesticide Storage: General Features by Frederick M. Fishel

“…Includes a pesticide storage checklist and additional resources. Published by the UF Department of Agronomy, October 2009. PI33/PI068: Secure Pesticide Storage: General Features (ufl.edu) …”
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Ultrasound and Carcass Merit of Youth Market Hogs by Chad Carr, Dwain Johnson, Mark Shuffitt

“…AN252/AN252: Ultrasound and Carcass Merit of Youth Market Hogs (ufl.edu) …”
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Plan de MiPirámide para el consumo diario de alimentos y calorías by Glenda L. Warren, Claudia Peñuela

“…It provides tables for determining portion sizes of each food group by calorie levels, and calorie levels by age, gender, and activity level. Published by the UF Department of Family Youth and Community Sciences, August 2010.     …”
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Nitrogen Fertilization of Strawberry Cultivars: Is Preplant Starter Fertilizer Needed? by Bielinski M. Santos, Alicia J. Whidden

“…HS1116/HS370: Nitrogen Fertilization of Strawberry Cultivars: Is Preplant Starter Fertilizer Needed? (ufl.edu) …”
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Ser un papá comprometido: ¿Qué significa esto? by Kate Fogarty, Garret D. Evans

“…FCS2141-Sp/FY1231: Ser un papá comprometido: ¿Qué significa esto? (ufl.edu) …”
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Effect of supplementation of phytoadditive mixtures on live weight, blood indices, hormonal profile and reproductive performance in Black Bengal goats by Amit Kumar Singh, Champak Bhakat, Upali Kisku, Muthupalani Karunakaran, Tapas Kumar Dutta

“…Blood parameters i.e. glucose, urea, total protein, albumin, globulin, ALT, AST, ALP, total lipids, cholesterol, and Triglycerides, WBC, RBC, Hb and PCV %; NEFA levels and hormones i.e. prolactin, cortisol, T3 and T4 were estimated in all three experimental groups. …”
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Инновационные методы моделирования для повышения эффективности оценки ESG-рисков в контексте развития «зеленой» экономики Республики Казахстан... by A.M. Nurgaliyeva, A.S. Jondelbayeva, Sh.U. Niyazbekova

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Advancing treatment choices: CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer by Paola Zagami, Angela Esposito, Beatrice Taurelli Salimbeni, Pier Paolo Maria Berton Giachetti, Roberta Scafetta, Matteo Lambertini, Massimo Di Maio, Giuseppe Curigliano, Carmen Criscitiello, Saverio Cinieri

“…Recently, the Italian Medicines Agency (AIFA) approved the possibility of switching between CDK4/6i for unacceptable toxicity. …”
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An Exploration of Determinants of Anemia in Pregnant Women at Buakayu Community Health Center Tana Toraja Regency by Erni Yetti R, Zadrak Tombeg, Anto J. Hadi, Sumardi Sudarman, Syamsopyan Ishak, Fitri Rahma Handayani

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Propiedades psicométricas de la Escala de Violencia Organizacional y Agresión en el Clima Laboral en Puerto Rico by Rita Vélez Alvarado, Adam Rosario Rodríguez, Abner Vélez

“…El índice de confiabilidad de la escala fue de .96 Alfa de Cronbach para las dimensiones de la Políticas y Procedimientos y Procedimientos y Respuestas y .92 Alfa de Cronbach para la dimensión de la Imposición de Prácticas Inseguras. …”
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Weed Management in Cotton by J. A. Ferrell, G. E. MacDonald, Pratap Devkota

“…Late-season weeds, while not as competitive as early-season weeds, may interfere with insecticide applications, may cause harvesting difficulties, and add seed in the soil seedbank. https://edis.ifas.ufl.edu/wg003 …”
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ACOPIO: Cuba's State Procurement and Distribution Agency by José Alvarez

“…This is EDIS document FE484, a publication of the Department of Food and Resource Economics, Florida Cooperative Extension Service, UF/IFAS, University of Florida, Gainesville, FL. …”
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Florida 4-H Camp Counselor Training Guide by Jessica Altum Cooper

“…https://edis.ifas.ufl.edu/4h398 …”
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The Critical Role of School Nurses: Supporting Health, Education, and Social Equity for Students with Disabilities by Zahra Saboohi, Fatemeh Guderzi

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Matematyczna aktywność badawcza uczniów klas początkowych. Między koncepcjami naukowymi i potocznymi by Alina Kalinowska

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