Evaluation of the effect of SmearOFF on Smear Layer Removal and Erosion of Root Canal Dentin by Sohela Fakher Mahdi, Diyar Khalid Bakr

“…For erosion variable, erosion was most evident in G4 (6% NaOCL/ 17% EDTA). There were no significant differences between G2 and G3 and also between G3 and G4 in both smear layers and erosion. …”
Get full text

Effectiveness of aspirin in preventing deep vein thrombosis following proximal femoral fracture surgery in Japan by Takao Ohmori, Kazukiyo Toda, Takuya Taoka, Takeshi Ishihara, Yasuo Ito

“…In Japan, there is a lack of evidence regarding its efficacy and safety in this context. …”
Get full text

Infant outcomes after exposure to Tdap vaccine in pregnancy: an observational study by Helen Petousis-Harris, Tony Walls, Patricia Graham, Nicola Austin, Linda Hill

“…We have not found any adverse events attributable to vaccine exposure.Conclusions These data add to the growing pool of evidence that the administration of Tdap vaccine during pregnancy is an appropriate strategy for reducing the burden of pertussis in infants.Clinical trial registration Australia New Zealand Clinical Trials Registry ACTRN12613001045707.…”
Get full text

Effect of the hour-1 bundle on clinical outcomes in patients with sepsis and septic shock: A protocol for systematic review and meta-analysis. by Shukun Hong, Hongye Wang, Xiaoguang Fan, Jian Liu, Lujun Qiao

“…Data synthesis will be performed via Review Manager 5.1.0.<h4>Expected results</h4>This systematic review will integrate all relevant studies to quantitatively estimate the effect size and clarify the role of the hour-1 bundle in sepsis management, contributing new evidence-based guidance to the field.…”
Get full text

The Case for Brutalist Honesty in Medical Education by Markle DT

“…Compared to the past, students now have access to a wealth of outside data to evaluate their curricular progress and career prospects against, and yet institutions are lagging behind in openly disclosing information related to metrics of student success (course passing rates, number of repeat students per class, Step 1 pass rate, etc.) that would engender trust and afford students greater agency in their academic decisions.Approach: In developing a new academic counseling office, the author deployed a method of using brutalist honesty as a means of student support, both in terms of answering all curriculum questions truthfully no matter the topic and with individualized data analytics to provide objective evidence as to student performance progress. The overarching goal was to foster student trust and have a positive relationship, both of which are necessary to give meaningful recommendations.Outcomes: As a result, the 2023 graduating medical school class, the first class to go through a full 4 years of this approach, rated the academic counseling office with a 96.2% satisfaction rate. …”
Get full text

Direction-Specific Signatures of Sport Participation in Center of Pressure Profiles of Division I Athletes by Stephen M. Glass, Scott E. Ross

“…Directional profiling of spontaneous COP motion may improve understanding of sport-related balance behavior, enhancing its application in therapeutic and performance monitoring contexts. # Level of evidence 3b…”
Get full text

Bidirectional causal associations between frailty measures and sleep disturbances: a two-sample Mendelian randomization study by Che L, Zang H, Bi Y, Wen B, Xu L

“…Genetic liability to short sleep duration and long sleep duration were associated with an increase in FFS.Conclusion: Our study provided genetic evidence supporting the bidirectional causality between frailty measures and sleep disturbances. …”
Get full text

Overuse Injury, Substance Use, and Resilience in Collegiate Female Athlete by Chelsea L Martin, Ellen Shanley, Chris Harnish, Amy M Knab, Shefali Christopher, Srikant Vallabhajosula, Garrett S Bullock

“…No significant differences were identified in substance use or overuse injury presentation between resilience groups, though further investigation is warranted. # Level of Evidence 3…”
Get full text

Ultrasound-detected osteophytes predict the development of radiographic and clinical features of hand osteoarthritis in the same finger joints 5 years later by Tore K Kvien, Hilde Berner Hammer, Ida K Haugen, Barbara Slatkowsky-Christensen, Alexander Mathiessen

“…Background Structural pathology may be present in joints without radiographic evidence of osteoarthritis (OA). Ultrasound is a sensitive tool for early detection of osteophytes. …”
Get full text

A Systematic Literature Review and Indirect Treatment Comparison of Efficacy of Repository Corticotropin Injection versus Synthetic Adrenocorticotropic Hormone for Infantile Spasms by Michael S. Duchowny, Ishveen Chopra, John Niewoehner, George J. Wan, Beth Devine

“…**Conclusions:** Based on the available limited evidence, results suggest RCI may be more efficacious for infantile spasms than synthetic ACTH treatments. …”
Get full text

Cost-Effectiveness and Budget Impact of Emerging Minimally Invasive Surgical Treatments for Benign Prostatic Hyperplasia by Bilal Chughtai, Sirikan Rojanasarot, Kurt Neeser, Dmitry Gultyaev, Stacey L. Amorosi, Neal D. Shore

“…This study evaluated the cost-effectiveness and budget impact of PUL and WVTT for men with BPH using long-term clinical outcomes. …”
Get full text

Percutaneous Vertebroplasty under Local Anesthesia for Osteoporotic Vertebral Compression Fractures: A Prospective Interventional Study by Dhruv Gupta, Varun Kumar Agarwal

“…This study included 40 patients with back pain with failure of conservative treatment for at least 3 weeks without nerve root compression sign with evidence of OVCFs on X-ray and Kummel sign positive who underwent PVP under local anesthesia. …”
Get full text

Ginkgo biloba L.: An Updated Review on the Pharmacological Activities, Pharmacokinetics and Drug Interactions by Zahra Moeinipour, Maryam Akaberi, Zahra Sobhani

“…However, herbal medicines are usually not standardized and despite their widespread use, there is limited scientific evidence on their safety and interactions. Ginkgo biloba L. is a medicinal plant whose biological properties have been confirmed in previous studies. …”
Get full text

Museographic narrating of dissonant heritage in Tianjin’s former international concessions by Maria Gravari-Barbas, Sandra Guinand, Yue Lu, Chensi Shen

“…The article captures and examines the main narratives from three perspectives: 1) revisiting the concession period as evidence of the beginning of modernity in China, which was a time in which celebrity life stories and the emergence of modern urban elements were praised; 2) considering the concessions as a dreamlike past of ‘others’ and ‘elsewheres’ belonging to a ‘foreign land’ and a context far removed from contemporary life in China, which favours the thematisation and leisure of Western architecture; and 3) selecting and targeting narratives focused on the heroes of the Republic of China (1912–1949) and the People’s Republic of China. …”
Get full text

Detecting Subtle Shifts: Comparing SME Performance Drivers Pre and During the Covid-19 Pandemic by Soza Sydney Simango, Helper Zhou

“…As expected, the results showed that the pandemic negatively impacted South African tourism SMEs. This was evident in decreased total asset value, sales volumes, revenue and the number of product offerings. …”
Get full text

Caesarean sections and private insurance: systematic review and meta-analysis by Ilir Hoxha, Medina Braha, Lamprini Syrogiannouli, David C Goodman, Peter Jüni, Bruno R da Costa

Get full text

Knowledge, attitudes and practices towards COVID-19 among multiethnic elderly Asian residents in Singapore: a mixed-methods study by Amudha Aravindhan, Alfred Tau Liang Gan, Ester Pei Xuan Lee, Preeti Gupta, Ryan Man, Kam Chun Ho, Sharon Cohan Sung, Ching-Yu Cheng, Moi Lin Ling, Hiang Khoon Tan, Tien Yin Wong, Eva Katie Fenwick, Ecosse Luc Lamoureux

“…However, important ethnic and socioeconomic disparities were evident, indicating that key vulnerabilities remain, which require immediate attention.…”
Get full text

Enhancing cancer care through a knowledge-sharing model: a systematic review of Project ECHO® programmes in India by Sangeeta Bhuyan, Shikha Yadav, Amit Verma, Shama Bhati, Ankit Anand, Sandeep Bhalla, Apoorva Karan Rai

“…The model’s adoption, retention, and reach are evident through 24 institutes/hubs implementing ECHO programmes in oncology. …”
Get full text

Relative Importance of Mode of Administration in Treatment Preferences among Plaque Psoriasis Patients in the United States by Steven R. Feldman, Anders Holmen Moeller, Sandra T. Erntoft Idemyr, Juan Marcos González

“…**Background:** Some aspects of psoriasis treatments can negatively influence patients’ quality of life. There is evidence from previous preference-elicitation research in psoriasis that administration characteristics are at least as important as treatment outcomes to patients. …”
Get full text

The Impact of Medicaid Preferred Drug Lists on Utilization and Costs of Antipsychotic Medication by Christian Frois, Thomas O’Connell, Jacqueline Pesa, John Fastenau

“…**Conclusions:** Although a majority of Medicaid states use PDLs to manage antipsychotic utilization, this analysis found no evidence of significant advantages for these Medicaid programs in terms of lowering percapita antipsychotic costs or increasing generic utilization.…”
Get full text