tDCS cranial nerve Co-stimulation: Unveiling brainstem pathways involved in trigeminal nerve direct current stimulation in rats by Alireza Majdi, Liyi Chen, Lars E. Larsen, Robrecht Raedt, Myles Mc Laughlin

“…Background: The effects of transcranial direct current stimulation (tDCS) are generally thought to result from the polarization of cortical neurons by the weak electric fields it creates. However, recent evidence suggests that some tDCS effects may be mediated through co-stimulation of peripheral or cranial nerves, particularly the trigeminal nerve (TN). …”
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Functional Outcome of Mesenchymal Stem Cells Vs. Hyaluronic Acid in Knee Osteoarthritis Kellgren-Lawrence Grade I-III At 6-and 12-Months Follow-Up: A Meta-Analysis by I Gusti Ngurah Wien Aryana, Febyan, Shianita Limena

“…Stem cell therapy, especially mesenchymal stem cells (MSCs), has revolutionized the treatment of knee OA. However, clinical evidence for MSCs in the treatment of knee OA is insufficient. …”
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Cognitive behavioural therapy plus Kiesler Circle Training (CBT+) versus CBT only for patients with interpersonal problems: study protocol for a randomised controlled feasibility t... by Stephan Köhler, Philipp Sterzer, Eva-Lotta Brakemeier, Karen Ollrogge, Daniel Schulze, Eva Friedel, Nina Romanczuk-Seiferth, Anna-Lena Siegerist, Anne Guhn

“…This study aims to provide evidence for the feasibility of KCT as a modular transdiagnostic add-on approach for patients with interpersonal difficulties.Ethics and dissemination This study obtained approval from the ethics committees at the Charité Berlin, the Medical School of Berlin and the University of Greifswald. …”
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Beyond the storms: Exploring predictors of posttraumatic stress and posttraumatic growth among survivors of hurricanes Irma and Maria in Puerto Rico by Marie-Claire Meadows, Noelle Serino, Dahianira M. Camacho-Monclova, Kaumudi Joshipura, Sarah R. Lowe

“…Conclusion: These findings provide novel evidence that different disaster-related exposures have distinct associations with the different PTG domains in Puerto Rico. …”
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Psychometric validation of the Danish BREAST-Q reconstruction module by Cecilie Balslev Willert, Karl Bang Christensen, Pernille Envold Bidstrup, Lene Mellemkjær, Anne-Marie Axø Gerdes, Lisbet Rosenkrantz Hölmich

“…The Rasch analyses disclosed evidence of local response dependence in eight scales. …”
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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? by Marka Crittenden, Sandra Demaria, C Norman Coleman, Jonathan Schoenfeld, Arta Monjazeb, Samir Khleif, Seema Gupta, Andrew Sikora, Zachary Morris, Chandan Guha, Stephen Shiao, Silvia Chiara Formenti, Bhadrasain Vikram, Mansoor M Ahmed

“…Recent evidence indicates that ionizing radiation can enhance immune responses to tumors. …”
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Examining The Impact of The COVID-19 Pandemic On Pediatric Orthopedic Cases: A Systematic Review and Meta-Analysis by Ahmadin Yusuf Rizal Susatyo, Nizar Al Rhaazi, Farhan Haidar Fazlur Rahman, Ismail Hadisoebroto Dilogo

“…Egger's test result showed no evidence of small-study effects (p = 0.22). Conclusion: This study found that the number of children admitted for orthopedic surgeries and other orthopedic treatments was not greatly impacted during the COVID-19 pandemic.…”
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Is preoperative imaging of sentinel lymph node in breast cancer necessary? A retrospective case control study by Michael J. Reinhardt, Björn Ohmstede, Luz Angela Torres-de la Roche, Rudy Leon De Wilde

“…Prospective studies might provide further evidence to omit preoperative SLN imaging in patients with T1-2 invasive breast cancer and clinically negative axilla.…”
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Triple antiviral therapy in patient with liver cirrhosis: complications and options of pharmacological treatment by M. V. Mayevskaya, I. N. Tikhonov, V. T. Ivashkin

“…AVT with good efficacy and sufficient safety profile in patients with compensated cirrhosis, is as well as for patients in the Waiting list for liver transplantation currently possible. …”
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Study of long-acting vs daily growth hormone: peak levels, AUC, action duration, and IGF-1 by Ashraf Soliman, Fawzia Alyafei, Nada Alaaraj, Noor Hamed, Shayma Mohamed, Ahmed Elawwa, Vincenzo De Sanctis

“…Sustained high IGF-1 levels with LAGH therapy may also increase risks for certain cancers and proliferative disorders, although evidence remains inconclusive. Discussion: While LAGH therapy offers improved adherence, it leads to nonphysiological, sustained high levels of GH and IGF-1, raising concerns about long-term metabolic effects. …”
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Duodenal Organoids From Metabolic Dysfunction-Associated Steatohepatitis Patients Exhibit Absorptive and Barrier Alterations by Alia Hadefi, Morgane Leprovots, Gilles Dinsart, Maryam Marefati, Marjorie Vermeersch, Daniel Monteyne, David Pérez-Morga, Anne Lefort, Frédérick Libert, Laurine Verset, Claire Liefferinckx, Christophe Moreno, Jacques Devière, Eric Trépo, Marie-Isabelle Garcia

“…Conclusion: This study provides evidence that the duodenal epithelium of MASH patients exhibits significant alterations in its nutrition-related and barrier functions. …”
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A study looking at how missed somatropin injections affect growth in children with growth hormone deficiency: a plain language summary of publication by Jane Loftus, Bradley S. Miller, Craig S. Parzynski, Jose Alvir, Yong Chen, Priti Jhingran, Anu Gupta, Mitch DeKoven, Victoria Divino, Jenny Tse, Jing He, Michael Wajnrajch

“…Health professionals should make treatment decisions based on all available evidence, not on the results of a single study. Glossary of commonly used terms Adherence – in this study, adherence refers to whether the children had enough medication ( somatropin ) to have daily injections as prescribed by their doctor. …”
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Direct and Indirect Methods for Studying Human Gut Microbiota by V. T. Ivashkin, O. S. Medvedev, E. A. Poluektova, A. V. Kudryavtseva, I. R. Bakhtogarimov, A. E. Karchevskaya

“…However, currently available evidence is insufficient to relate the obtained values (SCFA levels and ratio) to a particular disease with a high degree of certainty. …”
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Capacity Compensation Price Accounting of Coal-Fired Units Under the Background of New Power System by WANG Yongli, GUO Wenhui, LI Yuyang, GUO Lu, ZHANG Yuze

“…Therefore， traditional coal-fired units should seize policy opportunities to promote their transformation into system regulations and basic security power units to help build a new type of power system.…”
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Chronic NaAsO2 exposure promotes migration and invasion of prostate cancer cells by Akt/GSK-3β/β-catenin/TCF4 axis-mediated epithelial-mesenchymal transition by Zhi-Hui Zhang, Hai-Xin Yan, Ming-Dong Liu, Feng-Wen Niu, Kai Yao, Shi-Yao Feng, Xi Li, Yuan-Hua Chen, Dong-Dong Xie

“…These findings provide evidence that chronic arsenic exposure promotes migration and invasion of prostate cancer cells via an EMT mechanism driven by the AKT/GSK-3β/β-catenin/TCF4 signaling axis. …”
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Shift in the profile and prognostic implications in invasive fungal rhinosinusitis: experience of 10 years in a tertiary center by Raúl Mellidez-Acosta, Lidia Torres-García, Miguel Saro-Buendía, Natalia Jaramillo-Ángel, Javier Cabrera-Guijo, Catalina Bancalari-Díaz, Noelia Muñoz-Fernández, Lucas Fito-Martorell, Miguel Armengot-Carceller, Alfonso García-Piñero

“…Abstract Background Despite appropriate treatment, mortality of acute invasive fungal rhinosinusitis remains exceedingly high, surpassing 50%. Evidence on how to optimize its management is still limited. …”
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The association between resilience and fatigue among mariners during ocean voyages: a chain mediating effect of coping style and psychological stress by Zhanying Sun, Nan Tang, Xueyang Gan, Jingru Chen, Qingqing Su, Jie Song, Yuan Gao

“…The results have significant implications for the intervention and prevention of fatigue, providing additional evidence for the relationship between resilience and fatigue among mariners during ocean voyages.…”
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Local Anesthesia Versus Saddle Block for Open Hemorrhoidectomy: Cost-Analysis From a Randomized, Double Blind Controlled Trial. by Sikakulya, Franck Katembo, Ssebuufu, Robinson, Okedi, Xaviour Francis, Baluku, Moris, Lule, Herman, Kiyaka, Sonye Magugu, Muhumuza, Joshua, Selamo, Fabrice Molen, Bassara, Godefroy Nyenke, Waziri, Musa Abbas, Kithinji, Stephen Mbae, Mugisho, Munyerenkana Leocadie, Byamungu, Pahari Kagenderezo, Munihire, Jeannot Baanitse, Vahwere, Bienfait Mumbere, Kiswezi, Ahmed, Kyamanywa, Patrick

“…Being affordable, local anesthesia can help to increase the turnover of patients who would otherwise wait for the availability of anesthesia providers. …”
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The Impacts of Breakthrough Drug Classes on Total Healthcare Expenditures by Zeynal Karaca, Steven N. Wiggins

“…The costs and benefits of these newer and more expensive drugs, however, are controversial. The empirical evidence on whether newer drugs can decrease overall healthcare expenditures may enable private and public health policymakers to develop new drug benefit structures. …”
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Confounding Risk Factors in Developing Type 1 Diabetes Mellitus among Children and Adolescents at Sulaimani Chronic Diabetes Health Center by Pary Mohammad Azize, Chia H. Sadiq

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