UK policymaker and expert perspectives on the smoke-free generation policy: a qualitative study by Rachael L Murray, Joanne Morling, Nathan Davies, Tessa Langley, Manpreet Bains

“…There is substantial evidence for the benefits of raising the age of sale of tobacco but, despite several governments proposing SFG, the policy has faced significant challenge and has not been implemented at nation-state level. …”
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Knowledge, attitude, and practice of beef providers and consumers regarding microbial safety measures along the supply chain in Mizan-Aman, southwest Ethiopia by Girma Mamo Zegene, Seblework Mekonen Shegen, Seid Tiku Mereta

“…In this study both beef providers and consumers microbial safety status was assessed and will contribute evidences in public health protection strategies. Methods: A cross-sectional study was carried out among randomly selected beef retailers' owners, managers (n = 44) and systematically selected beef consumers (n = 422). …”
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Spatiotemporal clusters of acute respiratory infections associated with socioeconomic, meteorological, and air pollution factors in South Punjab, Pakistan by Munazza Fatima, Ibtisam Butt, Shahab MohammadEbrahimi, Behzad Kiani, Oliver Gruebner

“…Conclusions Our study provides evidence about environmental and socio-economic factors significantly associated with ARI incidence. …”
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Effects of falls prevention interventions on falls outcomes for hospitalised adults: protocol for a systematic review with meta-analysis by Anne-Marie Hill, Meg E Morris, David L Carey, Susan C Slade

“…The extent to which hospital falls are prevented by evidence-based practice, patient self-management initiatives, environmental modifications and optimisation of falls prevention systems awaits confirmation. …”
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The antimicrobial susceptibility patterns of diabetic foot ulcers in the South African public healthcare sector by M J Turner, S Leigh-de Rapper, T P Mokoena, S van Vuuren

“…These guidelines are developed using evidence-based medicine and are based on global susceptibility patterns rather than local susceptibility data, and may not provide the most appropriate treatment options. …”
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Cost-effectiveness Analysis of Ribociclib plus Letrozole versus Palbociclib plus Letrozole in the United Kingdom by Gaurav Suri, David Chandiwana, Adam Lee, Rohit Mistry

“…Clinical data from three randomized controlled trials (MONALEESA-2, PALOMA-1 and PALOMA-2 studies) were used, and supplemented with available real world evidence. Costs categories comprised of drug acquisition, medical management, and treatment of adverse events. …”
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Assessment of long-term changes in subvalvular aortic stenosis in patients following transcatheter aortic valve implantation by Vladlen V. Bazylev, Andrey B. Voevodin, Alexey S. Masyutin

“…The combination of these diseases during transcatheter aortic valve implantation (TAVI) is associated with significantly worse hospital outcomes, including cardiogenic shock, renal failure, and death. There is evidence that TAVI without prior treatment of left ventricular outflow tract obstruction leads to higher mortality due to exacerbation of subvalvular obstruction. …”
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Causal Effects of Sleep Traits on Angina Pectoris: Mediation by Cardiovascular Risk Factors by Zeng C, Ke Y, Li H, Zhang C, Chen J, Chen M

“…Getting up in the morning reduced the risk of SAP, while longer sleep duration lowered the risk of SAP and UAP. More evidences are required to clarify the roles of sleep traits and risk factors in AP.Keywords: sleep traits, angina pectoris, hypertension, Mendelian randomization, mediation…”
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Continuity and volume of bone cement and anti osteoporosis treatment were guarantee of good clinical outcomes for percutaneous vertebroplasty: a multicenter study by Zhen Cheng, Guangzong Ren, Ziyi Li, Xianda Gao, Di Zhang, Guiyue Chen

“…The purpose of our study was to identified the associated factors for good clinical outcomes and provide evidence for surgical strategy. Material and methods 186 patients who underwent PVP from January 2021 to January 2023 were reviewed retrospectively in the study. …”
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A bidirectional Mendelian randomization study integrating genome-wide association studies, expression quantitative trait locus, and methylation quantitative trait locus data reveal... by Zhou An, Meichun Zeng, Xianhua Wang

“…Conclusions: Our study provides evidence of a bidirectional causal association between smoking and Barrett’s esophagus from a genetic perspective, which sheds new light on the potential role of RBM43 as a mediator in facilitating the impact of smoking and Barrett’s esophagus.…”
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Temporal associations between microclimate, adult Aedes mosquito indices, and dengue cases at the residence level in Malaysia: Implications for targeted interventions. by Nur Athen Mohd Hardy Abdullah, Nazri Che Dom, Biswajeet Pradhan, Siti Aekball Salleh, Rahmat Dapari

“…The findings offer valuable insights for decision-makers, providing them with evidence-based information to implement targeted interventions and strategies aimed at controlling Aedes mosquito populations and mitigating the spread of dengue virus infections.…”
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What's the role of kindness in the healthcare context? A scoping review by Angela Greco, Laura G. González-Ortiz, Luca Gabutti, Daniel Lumera

“…Data were extracted and analyzed descriptively to summarize the evidence. Results 19 studies were analyzed and included in the review. …”
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Gender-transformative HIV and SRHR programme approaches for adolescents and young people: a realist review to inform policy and programmes by Isolde Birdthistle, Annabelle Gourlay, Sagri Singh, Damilola Walker, Migena Mata

“…In high HIV-burden jurisdictions, this is particularly true for adolescent girls and young women at disproportionate risk, while social and systemic barriers also impede the engagement of young men and gender minorities with health services. We sought evidence of approaches to promote sexual and reproductive health (SRH) outcomes by addressing gender transformation and removing structural barriers that broadly limit prospects for adolescents and young people.Methods We conducted a realist review to identify HIV and SRH-focused interventions with gender transformative mechanisms. …”
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Mortality and readmission following hip fracture surgery: a retrospective study comparing conventional and fast-track care by Kristin Haugan, Lars G Johnsen, Trude Basso, Olav A Foss

“…There was no statistically significant difference in sex, type of fracture, age or Charlson Comorbidity Index score at baseline between patients in the two pathways.Conclusions There was insufficient evidence to show an impact of fast-track care on mortality and readmission. …”
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Treatments for partial remission of major depressive disorder: a systematic review and meta-analysis by Marlies E Brouwer, Gert J Geurtsen, Damiaan A J P Denys, Joost Gülpen, Eva A M van Dis, Claudi L Bockting

“…Although one-third of patients remit partially, evidence for treatment efficacy is unclear. We provide an overview of treatment options and their efficacy.Study selection and analysis Embase, PsycINFO, Medline and SCOPUS were systematically searched through February 2023. …”
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Principles to award learning achievements for lifelong learning in health using micro-credentials: an international Delphi study by Sharon Mitchell, John Hart, Muntaha Gharaibeh, Graham T. McMahon, Anthea Rhoda, Siobhan Fitzpatrick, Tana Wuliji, Janusz Janczukowicz

“…The expert panel agreed on the need for standards that are competency-based, and require evidence of learning indicating what a learner can do. …”
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The antibiotic procurement saga: a long-neglected stewardship target to combat antimicrobial resistance in Pakistan by Shairyar Afzal, Mishal Bajwa, Nabeel Ahmed, Jawaria Jabeen, Mian Shahzeb Haroon, Rana Muhammad Zahid Mushtaq, Zikria Saleem

“…Results The study identified five central themes: (1) The state of antibiotic use in hospitals is characterized by a lack of antibiotic use policy, resulting in mostly empirical and irrational prescribing practices. (2) Medicine availability significantly influences prescribing decisions, often taking precedence over clinical needs. (3) The procurement process, although structured, is flawed owing to rigid adherence to the Standard Medicine List (SML). (4) Rationality in procurement is compromised by disregard for AMR, with decisions driven more by cost and demand than clinical evidence. (5) The clinical acumen of pharmacists is underutilized in procurement due to multifarious barriers. …”
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Efficacy and safety of antifibrotic drugs for interstitial lung diseases other than IPF: A systematic review, meta-analysis and trial sequential analysis. by Mei Yang, Yuying Tan, Ting Yang, Dan Xu, Mei Chen, Lei Chen

“…The risk of bias was rated with the RoB2 tool and certainty of evidence was assessed by the GRADE approach.<h4>Results</h4>17 studies with 1908 patients were included. …”
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“Gleaning a lot from the history and physical exam,” and “reasonably confident without imaging”: a qualitative study of primary care clinicians' management of patients with low bac... by Lynn Haslam-Larmer, Kathleen E. Norman, Andrea M. Patey, Isabella M. Thomas, Michael E. Green, Jeremy M. Grimshaw, Jill A. Hayden, Jan Hartvigsen, Noah M. Ivers, Hazel Jenkins, Simon D. French

“…Abstract Background Routine seeking of imaging for patients with low back pain is not concordant with the evidence-based recommendation that imaging is rarely of diagnostic value. …”
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Reassessment of disease severity routine laboratory tests in the COVID-19 infection by A. A. Simushev, E. Yu. Medvedeva, Yu. O. Shulpekova, V. M. Nechaev, M. R. Skhirtladze, I. R. Popova, V. T. Ivashkin

“…The preliminary results obtained in the study emphasize the importance of routine laboratory tests in assessment of coronavirus infection severity. An evident discrepancy between NEWS-2 score and X criterion may be very important for practice.…”
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