Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis by Kris Aubrey-Bassler, John-Michael Gamble, Jennifer R Donnan, Catherine A Grandy, Eugene Chibrikov, Carlo A Marra, Karissa Johnston, Michelle Swab, Jenna Hache, Daniel Curnew, Hai Nguyen

“…Subgroup analysis did show an increased risk of UTI with dapagliflozin only (RR 1.21; 95% CI 1.02 to 1.43, I2=0.0%), but no other analysis supported an increased risk of AKI, DKA, UTI or fracture.Conclusions Current evidence from RCTs does not suggest an increased risk of harm with SGLT2 inhibitors as a class over placebo or active comparators with respect to AKI, DKA, UTI or fracture. …”
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Exploring the allometry between ear saturated water accumulation and dry mass for diagnosing winter wheat water status during the reproductive growth by Tingxuan Zhuang, Ben Zhao, Syed Tahir Ata-Ul-Karim, Gilles Lemaire, Xiaojun Liu, Yongchao Tian, Yan Zhu, Weixing Cao, Qiang Cao

“…The indirect soil nitrogen deficiency, reduction of grain number per ear and early grain filling caused by drought were the three main factors leading to the decrease of ear WDI. The ear WDI effectively distinguishes varying degrees of water stress; however, it is essential to minimize errors resulting from its uncertainty before application. …”
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Phylogeographic breaks and how to find them: An empirical attempt at separating vicariance from isolation by distance in a lizard with restricted dispersal by Rancilhac, Loïs, Miralles, Aurélien, Geniez, Philippe, Mendez-Aranda, Daniel, Beddek, Menad, Brito, José Carlos, Leblois, Raphaël, Crochet, Pierre-André

“…Aim: Discontinuity in the distribution of genetic diversity (often based on mtDNA) is usually interpreted as evidence for phylogeographic breaks, underlying vicariant units. …”
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LMS MOODLE ЯК ЗАСІБ ОРГАНІЗАЦІЇ СЕРЕДОВИЩА ЗДОБУТТЯ ПЕДАГОГАМИ ПІСЛЯДИПЛОМНОЇ ОСВІТИ by Ірина Доманецька, Олена Федусенко, Олег Іларіонов, Ганна Красовська

“…Детально розглянуті питання побудови розгалужених структур курсів (елемент Lesson), організації проблемно-орієнтованого контенту з елементами групового опрацювання (Forum, Chat, Choice, Workshop, Wiki, MindMap), відстежування інтересів кожного слухача за вибором блоків навчальної інформації та зворотним зв'язком (елементи Lesson, Assignment, Feedback, Survay), оперативного моніторингу якості знань (елементи Lesson, Quize, Choice), організації навчального процесу за моделлю перевернутого класу. …”
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uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease by Yu Shen, Kaiyan Jiang, Dandan Tan, Min Zhu, Yusen Qiu, Pencheng Huang, Wenquan Zou, Jianwen Deng, Zhaoxia Wang, Ying Xiong, Daojun Hong

“…Abstract Background Neuronal intranuclear inclusion disease (NIID) is genetically linked to CGG repeat expansion in the 5’-untranslated region of the NOTCH2NLC gene, with nascent polyglycine-containing protein (uN2CpolyG) identified as a primary pathogenic factor. Emerging clinical evidence suggests that inflammation contributes to NIID pathogenesis, yet the underlying molecular mechanisms remain elusive. …”
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¿El área verde o el humedal afectan el precio de la vivienda, en un sector de Bogotá? by Carmen Rosa Montes-Pulido

“…Mediante uso de sistemas de información geográfica se determinó el tamaño de áreas verdes próximas al humedal y otros atributos de localización de las viviendas; los precios de los inmuebles se obtuvieron en el mercado de finca raíz en Bogotá. Con mínimos cuadrados ordinarios se relacionó el PV con atributos ambientales, de localización y socioeconómicos; el Índice de Moran, modelos de contigüidad y error espaciales permitieron analizar la dependencia espacial de los datos. …”
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Cancer mortality and sectors of employment: a cohort study in Italy by Stefania Massari, Lisa Bauleo, Claudio Gariazzo, Paola Michelozzi, Luca Dei Bardi, Nicolas Zengarini, Sara Maio, Massimo Stafoggia, Marina Davoli, Giovanni Viegi, Giulia Cesaroni, Alessandro Marinaccio, on behalf of the BIGEPI Collaborative Group

“…Conclusions The results showed an increased risk of cancer death in some traditional industrial sectors compared to the reference category of insurance activities such as construction and wood and leather products and limited evidence in sectors like cleaning, accommodation and food services and hairdressing. …”
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One-step diagnosis of infection and lung cancer using metagenomic sequencing by Shaoqiang Li, Yangqing Zhan, Yan Wang, Weilong Li, Xidong Wang, Haoru Wang, Wenjun Sun, Xuefang Cao, Zhengtu Li, Feng Ye

“…Onco-mNGS has emerged as a promising solution capable of accurately identifying infectious pathogens and tumors simultaneously. However, critical evidence is still lacking regarding its diagnostic performance in distinguishing between pulmonary infections, tumors, and non-infectious, non-tumor conditions in real clinical settings. …”
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Status of cerebrovascular autoregulation relates to outcome in severe paediatric head injury: STARSHIP, a prospective multicentre validation studyResearch in context by Shruti Agrawal, Claudia Smith, Stefan Y. Bogli, Michal M. Placek, Manuel Cabeleira, Deborah White, Esther Daubney, Adam Young, Erta Beqiri, Riaz Kayani, Diarmuid O'Donnell, Nazima Pathan, Suzanna Watson, Anna Maw, Matthew Ganrett, Hari Krishan Kanthimathianathan, Harish Bangalore, Santosh Sundararajan, Gayathri Subramanian, Dusan Raffaj, Avishay Sarfatti, Simona Lampareillo, Anton Mayer, Oliver Ross, Marek Czosnyka, Peter J. Hutchinson, Peter Smielewski, Carly Tooke, Caroline Payne, Holly Belfield, Amisha Mistry, Collette Spencer, Claire Jennings, Lara Bunni, Laura Anderson, Emily Morgan, Melanie James, Rebecca Beckley, Tahnima Khatun, Hafiza Khatun, Olivia Nugent, Richard Aldridge, Ruth Morgan, Julie Morcombe, Martin Quinton, Catherine Postlethwaite, Jenny Pond, Jessica Cutler, Caitlin Oxford

“…This provides additional evidence for the potential use of PRx for individualizing prognosis and treatment and pave way for further research in pTBI with the created database. …”
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Association between joint exposure to ambient air pollutants and carotid plaque: The mediating role of cardiometabolic risk factors by Yunfei Li, Ze Han, Xiaoyu Zhao, Yueruijing Liu, Zhiyuan Wu, Jinqi Wang, Xia Li, Xiuhua Guo, Lixin Tao

“…Background: Research has shown that exposure to joint air pollution is related to atherosclerosis, but little evidence has been found for carotid plaques. Our objective is to assess the association between exposure to joint air pollutants and carotid plaque and explore the mediating role of cardiometabolic factors in this relationship. …”
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Normativni izazovi proizvodnje energije korištenjem vjetra u isključivom gospodarskom pojasu Republike Hrvatske by Ivica Kinder

“…Svrha ovog istraživanja jest identificirati normativne i akcesorne pravne i nepravne izazove u primjeni Konvencije UN-a o pravu mora iz 1982., zakonodavstva EU-a i unutarnjeg prava Republike Hrvatske (RH) u vezi s mogućim iskorištavanjem obnovljivih izvora energije, napose energije vjetra na moru u RH, s posebnim osvrtom na isključivi gospodarski pojas. …”
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Insulin resistance surrogates are associated with all-cause mortality and cardiovascular mortality in population with metabolic syndrome: a retrospective cohort study of NHANES by Jinhao Liao, Linjie Wang, Lian Duan, Fengying Gong, Huijuan Zhu, Hui Pan, Hongbo Yang

“…Sensitivity analysis indicated most results were robust, but Bennett ISI did not exhibit significant outcomes in participants without CKD. Our study provides evidence that HOMA-β, QUICKI, IGR, e-IS, and Bennett ISI displayed a reverse correlation with all-cause mortality and cardiovascular mortality in participants with metabolic syndrome. …”
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El poder biopolítico oculto de la arquitectura. La descajanegrización del túnel entre dos edificios brutalistas en un campus de Berlín by Jorge Caminero Gabernet, Atxu Amann Alcocer

“…La controversia suscitada en el año 2020 a raíz de la posible demolición del conjunto edificatorio de gran calidad arquitectónica y el debate sobre su conservación como patrimonio edificado de la Arquitectura Brutalista, han sacado a la luz el túnel de conexión entre ambos, utilizado originalmente para transportar residuos biológicos y cadáveres de animales. …”
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SHoes for Adolescent PatEllofemoral pain: study protocol for the SHAPE Australian community-based, randomised clinical trial by Kim L Bennell, Kade L Paterson, Rana S Hinman, Jo-Anne Manski-Nankervis, Adam Bryant, Karen Elaine Lamb, Peixuan Li, Sam Shearer, Anurika P De Silva

“…The SHoes for Adolescent PatEllofemoral pain trial will provide the first RCT evidence on the efficacy of minimalist shoes compared with motion control shoes in adolescents with patellofemoral pain. …”
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Las multifacéticas remolachas: una reevaluación de sus posibilidades productivas a la luz de los conocimientos actuales by J. Rattin, M. Echarte, L. Barrera, J. Tognetti, A. Di Benedetto

“…Aunque el principal órgano de interés es en todos los casos la raíz engrosada, las tres remolachas constituyen cultivos muy diferentes entre sí, tanto en cuanto a sus características agronómicas como a los productos que se obtienen de ellos, por lo que generalmente se han estudiado por separado. …”
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Atrial fibrillation outcomes in patients from Asia and non-Asia countries: insights from GARFIELD-AF by Karen Pieper, Xian-hong Fang, Kai Sun, Ajay K Kakkar, Saverio Virdone, Shinya Goto, Gloria Kayani, Zhi-Cheng Jing, John Camm, Chun-Yan Cheng, Tian-Yu Lian, Xi-Jie Zhu, Xian-Mei Li

“…There was notable heterogeneity in oral anticoagulant (OAC) usage within the Asian countries.Conclusions Patients in Asian countries had a lower risk of all-cause mortality and major bleeding compared to the rest of the world. NOAC had evident benefits for reducing mortality and stroke across populations. …”
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A sex-disaggregated analysis of the prognostic value of lean type 2 diabetes mellitus in the adult population with acute myocardial infarction by Gwyneth Kong, Jaycie Koh, Jobelle Chia, Bryan Neo, Yiming Chen, Grace Cao, Bryan Chong, Mark Muthiah, Hui Wen Sim, Gavin Ng, Chieh Yang Koo, Chin Meng Khoo, Mark Yan-Yee Chan, Poay-Huan Loh, Nicholas W. S. Chew

“…Abstract Background Emerging evidence has demonstrated the unfavourable cardiovascular risk of individuals with lean type 2 diabetes mellitus (T2DM). …”
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Path model explaining the association between fear of falling and health-related quality of life in (pre-)frail older adults by Tjard Sattler, Sophie Gottschalk, Hans-Helmut König, Tobias Braun, Gisela Büchele, Michael Denkinger, Tim Fleiner, Corinna Nerz, Kilian Rapp, Martina Schäufele, Christian Werner, Judith Dams

“…Methods A theoretical path model was developed based on existing evidence and expert feedback and fitted to cross-sectional baseline data on 385 community-dwelling (pre-)frail older adults from the PromeTheus randomized controlled trial using robust weighted least squares estimation. …”
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Posljedice Brexita za pomorsko pravo Europske unije by Zoran Tasić

“…Trgovački sud u Londonu stoljećima rješava međunarodne sporove nastale iz prijevoza stvari morem. Približno 80 % svih sporova pred tim sudom, kao i Sudom za pomorske sporove, i danas su pomorski sporovi nastali iz pomorskih osiguranja i brodograđevnih sporova. …”
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The dose–effect relationship between acupuncture and its effect on primary insomnia: a systematic review and meta-analysis by Xiaoni Zhang, Xiaoni Zhang, Yue Wang, Chengyong Liu, Shan Qin, Liyu Lin, Liyu Lin, Can Dong, Wenzhong Wu, Wenzhong Wu, Zhaoming Chen

“…The results of GRADE assessment demonstrated that the level of evidence was very low to moderate, probably due to the poor methodological quality and the substantial heterogeneity among studies.ConclusionsA dose–effect relationship was found between the acupuncture dose and the PSQI scores. …”
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