Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model by Shunan Wang, Ming Shen, Bo Pang, Bo Zhou, Yuan Yuan, Mei Lu, Xiangling Deng, Min Yang, Shufang Liu, Qiong Wang, Mei Xue, Qisheng Xia, Zhixin Zhang

“…Methods We thoroughly examined the clinical features and genetic mutations evident in two patients with biallelic mutations in the DNAJC12 gene. …”
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An integrated microbiome- and metabolome-genome-wide association study reveals the role of heritable ruminal microbial carbohydrate metabolism in lactation performance in Holstein... by Chenguang Zhang, Huifeng Liu, Xingwei Jiang, Zhihong Zhang, Xinfeng Hou, Yue Wang, Dangdang Wang, Zongjun Li, Yangchun Cao, Shengru Wu, Sharon A. Huws, Junhu Yao

“…(a genus that was also showed to be linked to the ECM production via the mWASs analysis), GH24 (lysozyme), and 9,10,13-TriHOME (linoleic acid metabolism). …”
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The Metempiricism of Margins: Professor Anthony Aṣiwaju and the Circumference of Knowledge by Toyin Falola

“…My mind also went back to the frontier towns of Imeko and Ifonyin, to the journeys I took from Igboho to Cotonou via the scenic route far away from the chaotic Lagos-Badagry road. …”
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Evolution of burnout syndrome in Spanish healthcare professionals during and after the COVID-19 pandemic: psychosocial variables involved by Fernanda Gil-Almagro, Fernanda Gil-Almagro, Fernanda Gil-Almagro, F. Javier Carmona-Monge, Fernando J. García-Hedrera, Cecilia Peñacoba-Puente

“…IntroductionEvidence shows that throughout the COVID-19 pandemic, healthcare workers have experienced high levels of burnout. …”
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Potential public health impacts of gonorrhea vaccination programmes under declining incidences: A modeling study. by Lin Geng, Lilith K Whittles, Borame L Dickens, Martin T W Chio, Yihao Chen, Rayner Kay Jin Tan, Azra Ghani, Jue Tao Lim

“…<h4>Background</h4>Gonorrhea is the second most common sexually transmitted disease notified in Singapore in 2023. Evidence suggests that the 4CMenB vaccine designed to protect against Neisseria meningitidis infection may offer partial cross-protection against gonorrhea. …”
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Economic-productive analysis of a mixed cattle-bubaline model mixed model in the Northern region of Corrientes Province in Argentina by Pablo Maldonado-Vargas, Vanesa Guadalupe Mierke, Liliana Laura Pellerano, Guillermo Sebastián Grimaldi, Orlando Alberto Álvarez, Natalia Mercedes Vallejos, Margarita Rosa Itatí Romero, Francisco Daniel Romero, Alexis Sebastián Bandeo, Gonzalo Enrique Tuñón, José Luis Konrad

“… The production of buffaloes has been consistently growing in Argentina, with an increase in the number of animals and spread in 19 of the 23 provinces of the country, with an evident regional grouping. The Northeastern region of Argentina contains the provinces of Corrientes, Formosa, Chaco, Misiones, and Entre Rios, where 88.89% of the buffaloes, with Corrientes having the most significant numbers of animals and farmers. …”
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The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium by Coral Pardo-Esté, Coral Pardo-Esté, Francisca Urbina, Nicolas Aviles, Nicolas Pacheco, Alan Briones, Carolina Cabezas, Vicente Rojas, Valentina Pavez, Yoelvis Sulbaran-Bracho, Yoelvis Sulbaran-Bracho, Alejandro A. Hidalgo, Juan Castro-Severyn, Juan Castro-Severyn, Claudia P. Saavedra

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Intracranial pressure monitoring in patients with spontaneous onset of orthostatic headache by Linda D’Antona, Sanjay Cheema, Dwij Mehta, Fion Bremner, Laurence Dale Watkins, Ahmed Kassem Toma, Manjit Singh Matharu

“…Specific cut-offs for low and high ICP states were predetermined based on the best available current evidence. Results Thirty-eight patients (23 females, mean age 41 years ± 14SD) were identified. …”
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Emerging burden of post-cancer therapy complications on unplanned hospitalisation and costs among Australian cancer patients: a retrospective cohort study over 14 years by Rashidul Alam Mahumud, Md. Shahjalal, Padam Kanta Dahal, Md. Parvez Mosharaf, Sabuj Kanti Mistry, Kamrun Nahar Koly, Sujana Haque Chowdhury, Andre M. N. Renzaho, Jeff Gow, Khorshed Alam, Olivia Wawryk

“…Abstract Cancer treatment using systemic therapy and radiotherapy may cause post-therapy complications, resulting in increased unplanned hospitalisation. The evidence on such complications, their impact on unplanned hospitalisations, and associated costs is scant in Australia. …”
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Risk factors associated with degenerative glenohumeral osteoarthritis by Ravi Prakash, Nitin B Jain, Ziyi Chen, Folefac D Atem, Michael S Khazzam, Rashmi Pathak, Daniel Tai, Ursa BezanPetric, Estefanie Garduno Rapp

“…Since the shoulder is not a weight-bearing joint, the BMI-GH OA link is likely molecular and systemic, warranting further investigation.Level of evidence Prognostic level III.…”
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Komparasi Machine Learning Berbasis Pso Untuk Prediksi Tingkat Keberhasilan Belajar Berbasis E-Learning by Elin Panca Saputra, Siti Nurajizah, Mawadatul Maulidah, Nadiyah Hidayati, Taufik Rahman

“…While the attributes that have an influence to determine the algorithm on the level of accuracy are Practice Questions, Quizzes, Mid-Semester Exams, and Final Exams. it is evident from our previous studies that the PSO-based neural network algorithm does have a very good advantage. based on ANN is a method that has calculations that build several units of interconnected connectivity, the ANN method with predictive accuracy can be an efficient and good tool for forecasting and classification research in the field of education. …”
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Computational Phenotyping of Obstructive Airway Diseases: A Systematic Review by Bashir MBA, Milani GP, De Cosmi V, Mazzocchi A, Zhang G, Basna R, Hedman L, Lindberg A, Ekerljung L, Axelsson M, Vanfleteren LEGW, Rönmark E, Backman H, Kankaanranta H, Nwaru BI

“…An in-house quality appraisal tool was used. Evidence was synthesized, focusing on populations, variables, and computational approaches used for deriving phenotypes.Results: Of 120 studies included in the review, 60 focused on asthma, 19 on severe asthma, 28 on COPD, 4 on asthma-COPD overlap (ACO), and 9 on rhinitis. …”
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THE PUBLIC DEBT OF UKRAINE: A NEW DIMENSION OF DYNAMICS AND ARCHITECTURE OF THE MODEL FRAMEWORK OF THE MANAGEMENT SYSTEM by Serhii Petrukha, Nina Petrukha, Roman Miakota

“…The principal risk factors identified in the study are as follows: low rates of economic growth, a high level of dependence on foreign aid, demographic challenges and high costs for meeting the needs of the security and defence forces. Empirical evidence has demonstrated that the exchange rate and the real interest rate are the predominant factors influencing debt dynamics, thereby exacerbating the debt burden. …”
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Antimicrobial Resistance Surveillance of Skin and Soft Tissue Infections: Hospital-Wide Bacterial Species and Antibiograms to Inform Management at a Zonal Tertiary Hospital in Mwan... by Justine BN, Mushi MF, Silago V, Igembe Z, Muyombe J, Kishengena PP, Michael Jnr NS, Maganga MG, Massenga A, Tegete F, Massaga FA, Seni J

“…Revisiting SSTIs treatment guidelines at BMC and inclusion of SSTIs in the on-going AMR surveillance in Tanzania are recommended.Plain Language Summary: Tanzania National Action Plan on combating resistant bugs is exclusively focused on urinary tract infections and blood stream infections despite enormous impact conferred by skin and soft tissue infections.Bugs which are resistant to commonly used antibiotics were found more among patients admitted in the hospital in contrast to those attending outpatient clinics.This study highlights a pressing need to develop treatment guidelines based on generated local research-evidence to foster favorable patients’ outcomes.Keywords: skin and soft tissue infections, antimicrobial resistance, surveillance, Tanzania…”
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Comparison of GLP-1RAs vs Other Pharmacotherapy for Obesity by Andrew Overholser, Eric Czech, Linda Speer, Joel Wilson, Alex Overholser

“…Objectives: This review will summarize evidence comparing the safety and efficacy of GLP-1RAs or GLP-1RAs/GIP agonists with other pharmacologic treatments to achieve and maintain weight loss, improve quality of life, and reduce morbidity in obese adults. …”
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KEMAMPUAN LITERASI SAINS SISWA SMA DI KOTA KENDARI: DESKRIPSI & ANALYSIS by Erniwati Erniwati, Istijarah istijarah, La Tahang, Hunaidah Hunaidah, Vivi Hastuti Rufa Mongkito, Suritno Fayanto

“…As for the indicator using scientific evidence obtained percentage value of 52.69% with a lower category. …”
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Female Adolescent Soccer Players Utilize Different Neuromuscular Strategies Between Limbs During the Propulsion Phase of a Lateral Vertical Jump by Matthew D DeLang, Joseph P Hannon, Shiho Goto, James M Bothwell, J Craig Garrison

“…Quadriceps strength was measured via isokinetic dynamometry. Energy generation contribution (measured from maximal knee flexion to toe off) and vertical jump height were measured during the vertical component of the lateral vertical jump…”
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AI-based tumor-infiltrating lymphocyte scoring system for assessing HCC prognosis in patients undergoing liver resection by Zhiyang Chen, Tingting Xie, Shuting Chen, Zhenhui Li, Su Yao, Xuanjun Lu, Wenfeng He, Chao Tang, Dacheng Yang, Shaohua Li, Feng Shi, Huan Lin, Zipei Li, Anant Madabhushi, Xiangtian Zhao, Zaiyi Liu, Cheng Lu

“…However, their prognostic value in hepatocellular carcinoma (HCC) remains controversial, with different evidence. Given the heterogeneous outcomes in patients with HCC undergoing liver resection, this study aims to develop an AI-based system to quantify CD8+ TILs and assess their prognostic value for patients with HCC. …”
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Model Analisis Aktivitas Tutor Dalam Learning Management System Berdasarkan Data Log Menggunakan K-Means Dan Deteksi Outlier by Agusriandi Agusriandi, Elihami Elihami, Irman Syarif, Ita Sarmita Samad

“…Hasil temuan penelitian ini menunjukkan bahwa sebagian besar tutor memanfaatkan LMS hanya untuk mengumpulkan tugas, menampilkan materi dan sedikit yang disertai dengan aktivitas-aktivitas lain seperti forum, diskusi, quiz dan lainnya. Tutor dalam menampilkan standar isi atau konten hanya memberikan instruksi pengumpulan tugas dan menampilkan materi dengan menyertakan link atau video dari sumber lain. …”
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Diagnostics and treatment of gastroesophageal reflux disease: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, I. . A.s. Trukhmanov, Ye. K. Baranskaya, O. B. Dronova, O. V. Zayratyants, R. G. Sayfutdinov, A. A. Sheptulin, T. L. Lapina, S. S. Pirogov, Yu. A. Kucheryavy, O. A. Storonova, D. N. Andreyev

“…To present the latest data on adequate diagnostic methods, treatment approaches and features of rational pharmacotherapy of gastroesophageal reflux disease (GERD) based on the principles of evidence­based medicine to general practitioners. Summary. …”
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