The guanine nucleotide exchange factor DOCK5 negatively regulates osteoblast differentiation and BMP2-induced bone regeneration via the MKK3/6 and p38 signaling pathways by Ju Ang Kim, Soomin Im, Jiwon Lim, Jung Min Hong, Hye Jung Ihn, Jong-Sup Bae, Jung-Eun Kim, Yong Chul Bae, Eui Kyun Park

“…C21 significantly enhanced osteoblast differentiation and mineral deposition in mouse MC3T3-E1 cells and in human and mouse BMSCs. Dock5 knockout (KO) mice exhibited increased bone mass and mineral apposition rate, with their BMSCs showing enhanced osteoblast differentiation. …”
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Toxicity of Low-dose Graphene Oxide Nanoparticles in an in-vivo Wild Type of Caenorhabditis elegans Model by Ming-Hsien Tsai, How-Ran Chao, Jheng-Jie Jiang, Yu-Hsieh Su, Mariene-syne P. Cortez, Lemmuel L. Tayo, I-Cheng Lu, Hao Hsieh, Chih-Chung Lin, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Ching-Kai Su, Sen-Ting Huang, Wen-Li Hsu

“…Abstract Carbon-based engineered nanomaterials, such as graphene oxide nanoparticles (GO NPs), are widely available for application, but their potentially adverse health effects on humans still require investigation. In this study, the environmental levels of GO NPs are addressed to examine whether GO leads to adverse effects on an in-vivo model of Caenorhabditis elegans (C. elegans). …”
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The relationship between vitamin E and C intake with total activity of erythrocytes and breast milk superoxide dismutase in lactating mothers by Ninik Mudjihartini, Diyah Eka Andayani, Sheira Taflah Putri Handana

“… Background: Human milk contains many components, one of them is superoxide dismutase (SOD). …”
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Acute effects of physical exercise on cognitive function and neurotrophins in patients with type 1 diabetes: A systematic review by Emanuele Zanardo, Giulia Quinto, Francesca Battista, Federica Duregon, Marco Vecchiato, Chiara Bergia, Kirk Erickson, Andrea Ermolao, Daniel Neunhaeuserer

“…Methods: MEDLINE, Cochrane Library (CENTRAL database), EMBASE and SPORTDiscus were screened by 2 independent reviewers, who selected studies that analysed acute effects of physical exercise in patients with T1DM on BDNF levels or cognitive function tests before and after exercise. Studies in humans and English written were included. The quality of these studies was assessed using the respective Cochrane Risk of Bias tool. …”
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USING E-LEARNING TO PREVENT INFORMATIONAL STRESS OF EMPLOYEES WORKING REMOTELY by Oleksandra Pinchuk, Nataliia I. Pinchuk, Olena I. Bondarchuk, Valentyna V. Balakhtar, Kateryna S. Pavlenok

“…The following specific features of informational stress, by their information impact, are highlighted: 1) features associated with information overload, 2) features associated with human interaction with information technology, and 3) features associated with professional activities. …”
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Pamela J. Olubunmi Smith’s Translation Style in The Freedom Fight and Treasury of Childhood Memories by Tolulope Ibikunle

“…Literary works exhibit diverse linguistic components, coupled with social, religious and cultural aspects of human existence, hence translation of literary works could be regarded as one of the main communicative approaches across cultures. …”
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Clinical outcomes and long-term efficacy of high tibial osteotomy in treating knee instability: An updated systematic review by Mustamsir Edi, Aji Aulia Pandu, Adiwangsa Ahmad Abdilla, Akmalizzan Azfar Ahnaf

“…Eligible studies included human subjects with at least six months of follow-up and focused on HTO for knee instability. …”
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Comparative Analysis of Healthy Lifestyles in Peruvian University Students During and After the COVID-19 Pandemic by Carme Y. Baltazar-Meza, María Custodio

“…The present study aimed to examine the quality of healthy lifestyle practices in university students from the Faculty of Human Medicine and the Faculty of Education of a Peruvian university during and after the COVID-19 pandemic. …”
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Ultrasound Measurement of Lateral Patellar Displacement: A Cadaveric Validation Study by Lok Yin Ada Kwan, Alban Killingback, Philip J Adds

“…The cadavers had been donated for anatomical examination and research under the Human Tissue Act (2004). The distance between the lateral femoral condyle and the lateral edge of the patella were measured by B-mode real-time ultrasound, and then by direct measurement, in two positions, neutral and at 20° hip adduction…”
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Determination of the levels of some selected metals in ocimum lamiifolium in Wolaita Zone, Southern Ethiopia by Eyob Yishak, Teferi Tademe Dadebo

“… Medicinal plants have worldwide applications in the treatment of different types of human diseases. Among the medicinal plants of Ethiopia, Ocimum lamiifolium Hochst. …”
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Therapeutic efficacy of LysGH15 against necrotising pneumonia caused by Staphylococcus aureus in a rabbit model by Bowei Zhang, Liran Song, Yongran Wang, Meimei Zhang, Chong Chen, Hui Ning, Li Wang, Cao Qiu, Xinwu Wang, Changjiang Sun, Xin Feng, Wenyu Han, Wenyu Han, Bin Wang, Yalu Ji, Jingmin Gu, Jingmin Gu

“…IntroductionStaphylococcus aureus (S. aureus) is one of the most important zoonotic pathogens and can be transmitted to humans through the meat diet routes, causing necrotising pneumonia.MethodsThis study investigated the therapeutic effect of bacteriophage lysin LysGH15 on necrotising pneumonia in rabbit model caused by S. aureus.ResultsIn the in vitro experiments, 50 μg/mL LysGH15 not only significantly reduced the viable count (approximately 3.24 × 106 CFU/g) of chicken meat stored at 4°C for 48 h but also effectively reduced the viable count of chicken meat thawed at 4°C and 30°C, with reductions of approximately 1.42 × 106 CFU/g and 2.78 × 106 CFU/g, respectively. …”
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Effect of Double Masking with Silk or Cotton Over-masks on the Source Control Capabilities of a Surgical Mask by Adam F. Parlin, Mikhail Yermakov, Samuel M. Stratton, Susan R. Reutman, Theresa M. Culley, Patrick A. Guerra, Sergey A. Grinshpun

“…Finally, an additional study with five human subjects revealed no significant differences in perceived comfort (measured by proxies such as relative humidity, temperature, and CO2 level inside the mask) between single masking and double masking, as well as between double masking with either a silk or cotton over-mask.…”
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Impact of trainability on telomere dynamics of pet dogs (Canis lupus familiaris): An explorative study in aging dogs. by Julia Weixlbraun, Durga Chapagain, Jessica Svea Cornils, Steve Smith, Franz Schwarzenberger, Franz Hoelzl

“…Telomeres, essential for maintaining genomic integrity, undergo shortening with each cell division, leading to cellular senescence. Previous studies in humans have linked cognitive and social factors with telomere dynamics but in animals, such associations remain understudied. …”
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PET imaging of AAV9 and AAVBR1 trafficking in normal mice by Aditya Bansal, Shalini Sharma, Manasa Kethamreddy, Mukesh K. Pandey

“…Abstract Adeno-associated virus (AAV) mediated gene therapy is advancing and needs a noninvasive imaging tool to evaluate its effective targeting, biodistribution and clearance for precise use in humans. In this study, two serotypes of AAVs, AAV9-CMV-fLuc, and a brain targeting variant, AAVBR1-CMV-fLuc, are directly radiolabeled with the positron emission tomography (PET) radioisotope, 89Zr. …”
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Phytoconstituent analysis, bioactivity, and safety evaluation of various colors of Chrysanthemum morifolium flower extracts for cosmetic application by Angsana Neatpatiparn, Varaporn Buraphacheep Junyaprasert, Krit Thirapanmethee, Veerawat Teeranachaideekul

“…However, further studies, including human clinical trials, are needed to confirm these biological activities and safety profiles.…”
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Finger roots (Uvaria chemea) and African greenheart (Cylicodiscus gabunensis): Alternative potent therapy to sildenafil in erectile dysfunction by Etukudo Okon Jimmy, Grace Edet Bassey, Abijah Ekwere, Udoh Idorenyin Umoh, Adeyemi Fatai Odetayo, Udoh Nsikan Malachy

“…Further investigations are necessary to elucidate the underlying mechanisms of action, determine optimal dosages, and evaluate the long-term safety profiles of these herbal extracts for potential human applications.…”
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A Synoptic- and Remote Sensing-based Analysis of a Severe Dust Storm Event over Central Asia by Parya Broomandi, Kaveh Mohammadpour, Dimitris G. Kaskaoutis, Aram Fathian, Sabur F. Abdullaev, Vladimir A. Maslov, Amirhossein Nikfal, Ali Jahanbakhshi, Bakhyt Aubakirova, Jong Ryeol Kim, Alfrendo Satyanaga, Alireza Rashki, Nick Middleton

“…The extremely high PM concentrations (PM10 > 10,000 µg m−3 in Tashkent) could endanger both human health and the environment, especially in a region suffering from high susceptibility to wind erosion and significant land degradation and desertification. …”
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Preventive aspects and patient satisfaction with laser aided gingivectomy versus conventional method. An in-vivo comparative study by Aras Maruf Rauf, Ara Omer Fattah

“…Gingival diseases are among the most common health problems of human being. Gingivectomy, as a surgical interference can be performed with either scalpel or soft tissue Laser The objective of this study was to evaluate the preventive extent of Diode Laser in regards to gingivectomy associated complications beside the patient`s satisfaction. …”
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Security Challenges: Appraisal of Threats to Nigeria’s Sovereignty in the Fourth Republic (1999-2019) by Olanrewaju Rafiu Memud, Solomon A. Ojo

“… Peace and security asprimacy of sovereign states is crucial forharmonious human relations and economic development. In the recent past, insecurity has been the greatest challenge to Nigeria‟s corporate existence as a sovereign state.Ironically, these challenges are not externally propelled rather, they areinternally impelled byinter-ethnic conflict, religious insurrection, electoral violence, banditry, kidnapping, ritualism, pipeline vandalism, separatists‟ agitation, and farmers[1]herders crises among many others.These generate insecurity in the polity to the boiling point of fractured and failed state.The objective of the study, therefore, is to investigate the nexus between internally induced insecurity and failed stateposture experienced in the Nigeria‟s Fourth Republic. …”
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Enhanced CO2 Capture Performance Using Methyl Diethanolamine-functionalized Silica Gels: Assessing CO2 Capture Capacity by Petpitcha Boonmatoon, Pacharapol Nokpho, Pornpote Piumsomboon, Benjapon Chalermsinsuwan

“…This causes harm to the environment and to humans. In 2023, atmospheric CO2 levels rose to 420 ppm, marking a new record high. …”
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