AN ANALYSIS OF FACILITY ASSESSMENT OF PRIMARY HEALTH CARE IN NIGERIA: A MICRO-EVIDENCE FROM KADUNA SATE by Gimba Victor Kyari, Micah Dogara, Selbyen Evelyn Gimba

“… This survey was conducted on facility readiness at the selected 239 facilities to determine the level of site preparedness with respect to human resource (health providers and volunteer community mobilizers), equipment availability and rate of service utilization.The survey of program data spanned over a 3-day period with visits to 115 facilities (40 in the Southern and Northern Zones each and 35 in the Central Zone of the state) and questionnaires administered to 2 Healthcare workers and 5 Clients per facility on their ANC days. 23 enumerators were recruited for data collection. …”
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Insilico targeting of virus entry facilitator NRP1 to block SARS-CoV2 entry. by Nousheen Bibi, Maleeha Shah, Shahzad Khan, Muhammad Shahzad Chohan, Mohammad Amjad Kamal

“…The crystallographic structure of the b1 domain of human NRP1 (PDB entry: 7JJC) was used for this purpose. …”
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A growing degree day model determines the effect of temperature stress on diverse chickpea genotypes by Cara Jeffrey, Cara Jeffrey, Cara Jeffrey, Laura Ziems, Laura Ziems, Brent Kaiser, Brent Kaiser, Richard Trethowan, Richard Trethowan

“…Chickpeas are a globally crucial agricultural product, currently at risk due to human-induced climate change. There has been little research into the impact of heat stress on chickpea compared to other crops, but it is known that heat stress can cause up to 100% yield loss. …”
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Targeting transforming growth factor-β1 by methylseleninic acid/seleno-L-methionine in clear cell renal cell carcinoma: Mechanisms and therapeutic potential by Aseel O. Rataan, Yan Xu, Sean M. Geary, Yousef Zakharia, Eman S. Kamel, Youcef M. Rustum, Aliasger K. Salem

“…This study analyzed their expression in human ccRCC cell lines and patient tumor biopsies. …”
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Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases by Mingyu Wu, Ke Li, Jiabin Wu, Xianyi Ding, Xiaotong Ma, Wenhong Wang, Weihua Xiao

“…Diverse liver diseases are characterised by late diagnosis and rapid progression and have become one of the major threats to human health. To delay the transition from benign tissue lesions to a substantial organ injury, scientists have gradually applied natural compounds derived from plants as a complementary therapy in the field of hepatology. …”
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Pleiotropic effects of a recessive Col1a2 mutation occurring in a mouse model of severe osteogenesis imperfecta. by Michelangelo Corcelli, Rachel Sagar, Ellen Petzendorfer, Mohammad Mehedi Hasan, Fleur S van Dijk, Anna L David, Pascale V Guillot

“…To investigate this, one of the OI murine models was used, i.e. the oim/oim (OIM) mice, which closest resembling severely deforming OI in humans. We showed that in OIM, the Col1a2 mutation results in a multifactorial inhibition of the osteogenic differentiation and maturation as well as inhibition of osteoclastogenesis. …”
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Spatial-temporal evolution of habitat quality in tropical monsoon climate region based on “pattern–process–quality” – a case study of Cambodia by Kang Junmei, Yang Fengshuo, Wang Jun, Liu Yang, Fang Dengmao, Jiang Chengcheng

“…The results show that (1) during 2000–2022, forest in Cambodia covered a wide range, showing a landscape pattern mainly distributed in the east and west. (2) The degree of fragmentation of impervious landscape pattern increased gradually from 2000 to 2022, indicating that it was seriously affected by human activities and natural factors, and with the increase in elevation and slope, the area of various types converted to impervious decreased. (3) During 2000–2022, high habitat quality areas were concentrated in Tonle SAP Lake in the east, southwest, and central part of Cambodia, while low habitat quality areas were concentrated in the central part. (4) Natural factors, socio-economic factors, policies, and regulations all have an impact on the change in land use pattern and habitat quality in Cambodia.…”
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The shear bond measurement of two self-adhesive composite resins to both enamel and dentin (An in vitro study) by Abdulkareem Ramadhan Ibrahim

“…Methods: Sixty freshly extracted human third molar teeth were chosen for this study (thirty for enamel samples and thirty for dentin samples). …”
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The weight-adjusted-waist index predicts all-cause and cardiovascular mortality in hypertension by Yu Zheng, Zixing Nie, Yifan Zhang, Tao Sun

“…BackgroundWeight-adjusted-waist (WWI) is a novel indicator of obesity that reflects the degree of central obesity in the human body.ObjectivesThe study aimed to explore the relationship between WWI and mortality in hypertensive individuals.MethodsCross-sectional data from the 2001–2018 National Health and Nutrition Examination Survey (NHANES) dataset were used in this study. …”
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In pursuit of evidence: A need to transform Ayurvedic education by Sruthi G, Megha

“…India can emerge as a global leader in the area of integrative medicine, with its repository of several indigenous medical systems, and talented human capital in biomedical sciences. It is time we take the plunge.…”
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Financial and economic consequences of the war for Ukraine by Olena Lytvyn

“…Most of the companies that have already optimized their staff do not intend to reduce it further, seeing human resources as a prerequisite for a gradual economic recovery. …”
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TRANSNATIONAL THREATS AND FOREIGN POLICY SHIFTS: INVESTIGATING THE IMPACT OF GLOBALIZATION ON WEST AFRICAN COUNTRIES by AHMED OLAWALE MOLIKI, NURUDEEN ABIDEMI AKANBI

“… Globalisation is a blessing as well as bane to humanity. Its impact on societies around the globe is diverse, presenting both opportunities and challenges. …”
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Efficacy of green tea mouth wash as an adjunct to non-surgical periodontal treatment in patients with chronic periodontitis by Sarwar Qasim Mustafa, Dilyar Ahmed Baban

“…Patients and methods: A randomized controlled trial on 45 healthy humans with mild to moderate localized chronic periodontitis. …”
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Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice by Xiao-ming Wang, Cai-ming Qin, Dou Li, Xin-ran Xu, Xiao-jing Pan, Hui Xue

“…Further in vitro determination of the underlying mechanisms using human fetal palatal mesenchymal cells (hFPMCs) revealed that TCDD suppressed a wide variety of osteogenic genes responsible for osteoblast commitment and bone matrix synthesis and mineralization, through activating aryl hydrocarbon receptor (AhR) signaling and subsequently inhibiting estrogen signaling. …”
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Archaeological Site Detection: Latest Results from a Deep Learning Based Europe Wide Hillfort Search by Jürgen Landauer, Simon Maddison, Giacomo Fontana, Axel G. Posluschny

“…While automation significantly reduces manual workload, human verification remains critical for refining AI predictions and addressing false positives. …”
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Nonylphenol exposure increases the risk of Hirschsprung’s disease by inducing macrophage M1 polarization by Xuefeng Yang, Chengyan Tang, Daiwei Zhu, Xingrong Xia, Qing Du, Lu Huang, Jianguo Liu, Yuanmei Liu

“…Our results showed that NP concentration and LINC00294 were significantly associated with HSCR occurrence and macrophage polarization in human HSCR specimens. Moreover, NP promoted macrophage M1 polarization. …”
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Electroencephalography Correlation of Ketamine-induced Clinical Excitatory Movements: A Systematic Review by Emine M. Tunc, Neil Uspal, Lindsey Morgan, Sue L. Groshong, Julie C. Brown

“…Two independent reviewers assessed papers based on eligibility criteria, which included human studies where EEG recordings were obtained during ketamine administration. …”
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Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action by Aurangzeb Sana, Aurongzeb Muhammad, Shamim Shahbaz, Rashid Yasmeen, Khan Khalid Mohammed, Aziz Tariq, Alharbi Metab, Alasmari Abdullah F.

“…This bacterial complex is reflected as an attractive target for drug development due to its presence in disease-causing microorganisms and concurrent absence in humans. The objective of this research was to identify certain promising drug candidates that could excessively stimulate the HslV protease, leading to uncontrolled protein breakdown in the pathogens. …”
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Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds by Bortoluzzi, Chiara, Restoux, Gwendal, Rouger, Romuald, Desnoues, Benoit, Petitjean, Florence, Bosse, Mirte, Tixier-Boichard, Michèle

“…Livestock biodiversity is declining globally at rates unprecedented in human history. Of all avian species, chickens are among the most affected ones because many local breeds have a small effective population size that makes them more susceptible to demographic and genetic stochasticity. …”
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Neuroprotective Potentials Of Extracts From Moringa Oleifera And Musa Sapientum Against Cadmium Chloride-Induced Neurotoxicity In Rats Cerebri by Adelaja Akinlolu

“… Cadmium (Cd)-exposure in humans causes nervous system dysfunctions. In rats, Cd-exposure resulted in increases of nitric oxide and lipid peroxidation levels in the hippocampus. …”
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