Determining the alignment of assessment items with curriculum goals through document analysis by addressing identified item flaws by Humaira Fayyaz Khan, Shazia Qayyum, Huma Beenish, Rehan Ahmed Khan, Samina Iltaf, Lubna Rani Faysal

“…Pre-hoc reports from mid-stake assessments across five academic years were analyzed, covering both preclinical and clinical years. A total of 2,400 multiple-choice questions (MCQs) were reviewed for the mid-stake exams against the institutional checklist in which flaws were categorized into three types: test wiseness, irrelevant difficulty, and miscellaneous flaws. …”
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Analysis of Healthcare Resource Utilization and Costs after the Initiation of Biologic Treatment in Patients with Ulcerative Colitis and Crohn’s Disease by Sue Perera, Shibing Yang, Marni Stott-Miller, Joanne Brady

“…The highest proportion of patients who continued with the same biologic after 1-and 2-years had initiated therapy with infliximab for both indications (although at the 1-year follow-up for CD, the highest proportion continued to use natalizumab, but this was a small sample [n=15]). …”
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Blood pressure, gallstones, and age at first cholecystectomy in U.S. adults: a cross-sectional study by Yue Zhang, Ruifeng Duan, Xin Chen, Lijuan Wei

“…This study assessed the association between hypertension (HTN) and both the prevalence of gallstones and the age at first cholecystectomy among U.S. adults. …”
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Spartina alterniflora invasion significantly alters the assembly and structure of soil bacterial communities in the Yellow River Delta by Pengyuan Sun, Yuxin Wu, Pengcheng Zhu, Jingfeng Wang, Jingfeng Wang, Xiaona Yu, Weihua Guo

“…In comparison, S. alterniflora-associated bacterial communities were enriched with both sulfate-reducing bacteria (SEEP-SRB1) and sulfate-oxidizing bacteria (Sulfurimonas), which maintained a dynamic balance in the local sulfur-cycle, and thereby enhanced S. alterniflora growth. …”
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CHATGPT: ATTITUDES AND EXPERIENCES OF TECHNICAL UNIVERSITY STUDENTS IN UKRAINE by Oksana Chugai, Kateryna Havrylenko

“…While students expressed moderate satisfaction with ChatGPT’s support and its perceived enhancement of their grasp of course material, they also acknowledged its positive impact on their academic performance both in technical sciences and humanities. Despite its user-friendly interface, students identified several challenges and limitations, including ChatGPT’s inability to address technical issues and its occasional dissemination of inaccurate or outdated information, necessitating verification. …”
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CD21low B cells reveal a unique glycosylation pattern with hypersialylation and hyperfucosylation by Peter Tobias Felixberger, Peter Tobias Felixberger, Geoffroy Andrieux, Andrea Maul-Pavicic, Andrea Maul-Pavicic, Sigune Goldacker, Sigune Goldacker, Ina Harder, Ina Harder, Sylvia Gutenberger, Sylvia Gutenberger, Jonathan J. M. Landry, Vladimir Benes, Till Fabian Jakob, Melanie Boerries, Melanie Boerries, Lars Nitschke, Reinhard Edmund Voll, Reinhard Edmund Voll, Klaus Warnatz, Klaus Warnatz, Baerbel Keller, Baerbel Keller

“…The glycosylation pattern of B cells in CVID patients has not been addressed to date.ObjectiveThe objective of this study was to examine the surface glycome of B cells in patients with CVID and associated immune dysregulation.MethodsWe performed surface lectin staining on B cells from peripheral blood and tonsils, both ex vivo and after in vitro stimulation. Additionally, we examined the expression of glycosylation-related genes by RNAseq in naïve-like CD21low B cells ex vivo, as well as in naïve CD21pos B cells from healthy controls after in vitro stimulation.ResultsUnlike CD21pos B cells, naïve-like CD21low B cells from CVID patients and CD21low B cells from healthy controls exhibited a unique glycosylation pattern with high levels of α2,6 sialic acids and fucose. …”
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Filtration and Breathability of Nonwoven Fabrics Used in Washable Masks by Thomas W. Bement, David J. Downey, Ania Mitros, Rebecca Lau, Timothy A. Sipkens, Jocelyn Songer, Heidi Alexander, Devon Ostrom, Hamed Nikookar, Steven N. Rogak

“…The measured filtration and pressure drop of both the homogeneous and heterogeneous multi-layer fabric combinations agreed with the estimations from a model assuming layers filter independently. …”
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A Cost-benefit Analysis of Using Polyethylene Glycol Hydrogel Sealant versus Fibrin Glue as a Dural Sealant for Posterior Fossa Surgery in the United States by Marissa J. Carter

“…**Results:** In the base case, the cost of the hospital stay for the original surgery, which excludes the cost of complications, dominated costs for both cohorts. On a per patient basis, the use of fibrin glue cost $1666 more than the use of DuraSeal. …”
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The Association of Economic Outcome and Geriatric Syndromes among Older Adults with Transcatheter Aortic Valve Replacement (TAVR) by Min Ji Kwak, Rafia Rasu, Robert O. Morgan, Jessica Lee, Nahid J. Rianon, Holly M. Holmes, Abhijeet Dhoble, Dae Hyun Kim

“…When the interactions of the geriatric syndromes were tested for association with the outcomes, delirium in the absence of dementia but presence of frailty showed the strongest association with cost (increase by 45.1%, 95% CI 26.45~66.45), and delirium in the absence of both dementia and frailty showed the strongest association with LOS (increase by 74.5%, 95% CI 62.71~87.13). …”
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Efficacy and safety of repetitive transcranial magnetic stimulation in the treatment of male smokers with tobacco use disorder: a randomized controlled trial by Salma W. Mousa, Adel A. Badawy, Gehan F. Attia, Wesam A. Ghareeb

“…Active r-TMS treatment, delivered over 15 sessions (5 sessions weekly for 3 consecutive weeks), significantly reduced the number of cigarettes smoked daily (p = 0.001), nicotine dependence (p = 0.023), withdrawal symptoms (both self-reported and observer-rated) (p = 0.001), and craving (p = 0.007) compared to the sham treatment. …”
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Effect of pore throats on the reservoir quality of tight sandstone: A case study of the Yanchang Formation in the Zhidan area, Ordos Basin by Wei Fanrong, Yan Xinzhi, Bai Yubin, Bai Yanjun, Zhou Kai

“…Large pore throats, which account for less than 15% of all pore throats, contribute more than 90% of the permeability, while pore throats less than 0.8 μm in diameter are major contributors to the reservoir space, and both the porosity and permeability decrease as the pore-throat diameter decreases.…”
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The Effects of Single and Bimetallic Silicon Composite Shields in Medical Imaging Methods: A Monte Carlo Study by Abbas Ali Nazeri, Reza Malekzadeh, Parinaz Mehnati, Soheila Refahi

“…Results: The results showed the beam reduction ability for both the mono- and the bimetallic composites. The mass attenuation coefficients of Bi2O3, WO3, and SnO2 at 80 KeV were 0.38, 0.33, and 0.57 cm2/gr, respectively. …”
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Enhancing collaborative clinical reasoning among multidisciplinary healthcare teams in a neurosurgery ICU: insights from video-reflexive ethnography by Ching-Yi Lee, Ching-Hsin Lee, Sze-Yuen Yau, Hung-Yi Lai, Po-Jui Chen, Mi-Mi Chen

“…Active information gathering, both verbal and behavioral, was crucial for obtaining real-time patient insights. …”
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Awake brain MRSI reveals anesthetic sensitivity and regional aging effects on [13C]bicarbonate metabolism in mice by Maiko Ono, Rena Kono, Kosei Hirata, Kosei Hirata, Keita Saito, Motonao Nakao, Yoichi Takakusagi, Rikita Araki, Akira Sumiyoshi, Yuhei Takado

“…Although the signal for [1-13C]lactate, a product of glycolysis metabolized from [1-13C]pyruvate, was detectable in multiple brain regions that include the orbitofrontal cortex and hippocampus in both awake and anesthetized mice, the signal for [13C]bicarbonate metabolized from [1-13C]pyruvate was only detectable in the brains of awake mice. …”
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The Hidden Economic Consequences of Migraine to the UK Government: Burden-of-Disease Analysis Using a Fiscal Framework by Rui Martins, Samuel Large, Rachel Russell, Gary Surmay, Mark P. Connolly

“…**Conclusions:** This fiscal analysis monetizes the occupational consequences of migraine to the UK government, both in terms of lost tax revenue and transfer payments. …”
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Virgin coconut oil lessens trichloroacetic acid assault on the stomach and intestine of rats via enhancement of Nrf2 but inhibition of TNF-α, IL1β/NF-kB signalling pathway by OO Oladokun, KO Ajeigbe, MA Adelakun

“…Similarly, intestinal crypt depth assessment and inflammatory cell infiltration earlier increased in the TCA group was quashed by VCO. Still, both gastric mucous and goblet cells hitherto reduced were significantly enhanced by VCO alone or in combination with 5-FU. …”
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Straw return combined with water-saving irrigation increases microbial necromass accumulation by accelerating microbial growth-turnover in Mollisols of paddy fields by Peng Chen, Junzeng Xu, Kechun Wang, Zhongxue Zhang, Zhaoqiang Zhou, Yawei Li, Tiecheng Li, Tangzhe Nie, Qi Wei, Linxian Liao

“…Despite this treatment enhancing microbial respiration, strong positive correlations were found between soil organic carbon (SOC) content and both microbial growth rate and necromass accumulation. …”
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Composite microbial agent improves cotton yield and resource use efficiency under mild salt stress by optimizing plant resource allocation by Xiao Zhao, Panpan Guo, Xiong Wu, Meng Zhu, Shaozhong Kang, Taisheng Du, Jian Kang, Jinliang Chen, Ling Tong, Risheng Ding, Wanli Xu, Guangmu Tang

“…The results demonstrated that STC-PGPR enhanced SY and resource use efficiency under both S1 and S2 salinity levels, with significant improvements observed in G2S1 and G1S2 . …”
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Association between mixed exposure of non-persistent pesticides and liver fibrosis in the general US population: NHANES 2013–2016 by Shuge Shu, Yuan Li, Xiangyu Yu, Xinting Chen, Ummara Abdullah, Yongquan Yu

“…In single exposure analysis, significant and persistent associations were identified for 3,5,6-trichloropyridinol (TCPY), para-nitrophenol (PNP), glyphosate (GLYP) and 2,4-dichlorophenoxyacetic acid (2,4-D) exposure with both continuous and dichotomous liver fibrosis outcomes. …”
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Predicting nighttime black ice using atmospheric data for efficient winter road maintenance patrols by Jinhwan Jang

“…To evaluate the predictive models, reference data were obtained based on the physical principle that black ice forms when the road surface temperature drops below both the freezing point and the dew point temperature. …”
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