One-step diagnosis of infection and lung cancer using metagenomic sequencing by Shaoqiang Li, Yangqing Zhan, Yan Wang, Weilong Li, Xidong Wang, Haoru Wang, Wenjun Sun, Xuefang Cao, Zhengtu Li, Feng Ye

“…Abstract Background Traditional detection methods face challenges in meeting the diverse clinical needs for diagnosing both lung cancer and infections within a single test. …”
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BOKO HARAM OPERATIONS IN NIGERIA:THE NEXUS BETWEEN FREEDOM FIGHTERS AND TERRORISTS by Musa Abdulkarim Itodo, BINTA YAKUBU SULE

“…Using the historical approach, primary and secondary data,and the study found that both the terrorist and freedom fighter suffer from one form of marginalization or the other prompting agitations. …”
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Beverage consumption modifies the risk of type 2 diabetes associated with ambient air pollution exposure by Chaonan Fan, Wenjuan Wang, Wenxue Xiong, Zhiyao Li, Li Ling

“…Conversely, those with > 1 cup of SSB had a higher T2D risk associated with both NO2 and NOX (Pheter <0.05). Conclusions: This study highlights the significant role of beverage consumption in mitigating or exacerbating the T2D risk associated with long-term NO2 and NOX exposure.…”
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Long-term trends in the burden of multiple myeloma in China: a Joinpoint regression and age-period-cohort analysis based on GBD 2021 by Yanyu Zhang, Quanxin Su, Jiawen Yu, Xiuli Sun

“…The ASIR and ASMR of males are higher than those of females overall, and both were increasing with age. The ASIR exhibited a gradual upward trend, while ASPR (AAPC = 6.43, 95% CI: 5.90, 6.96) demonstrated the most substantial increase. …”
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Prevalence and associated factors of intestinal parasitic infections in the Badi indigenous communities of Western Nepal by Jitendra Gautam, Rajendra Prasad Parajuli, Kishor Pandey

“…The highest prevalence was observed for Giardia lamblia at 16.1% (n = 33), followed by Ascaris lumbricoides at 5.9% (n = 12), Entamoeba histolytica at 2.9% (n = 6), and both Enterobius vermicularis and Hymenolepis nana at 1% (n = 2). …”
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NUAK1 acts as a novel regulator of PD-L1 via activating GSK-3β/β-catenin pathway in hepatocellular carcinoma by Chao-Yan Yao, Hang-Tian Tao, Jin-Jin He, Feng-Yi Zhu, Cui-Qing Xie, Yu-Na Cheng, Ji-Qin Li, Zhuang-Zhuang Liu, Chun-Yu Hou, Xue-Li Liu, Yong-Li Fan, Dong Fang, Xin-Rui Lv

“…Results NUAK1 expression was negatively correlated with CD8+ T cell infiltration in tumor tissues from HCC patients and mice xenograft model. Both gain and loss of functions have identified NUAK1 promoted PD-L1 expression at transcriptional level in HCC cells. …”
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Efficacy of Physiologically Active nutrients in the Treatment of Asthenic Disorders in Patients with Chronic Diffuse Liver Diseases by M. V. Mayevskaya, M. A. Morozova, A. G. Beniashvili, V. D. Lunkov, V. T. Ivashkin

“…The quality of patients’ life according to the SF36 questionnaire also improved due to both physical and psychological components (p = 0.003). 16 patients continued taking the preparation for another 8 weeks to maintain the achieved result. …”
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Efficacy and safety of antifibrotic drugs for interstitial lung diseases other than IPF: A systematic review, meta-analysis and trial sequential analysis. by Mei Yang, Yuying Tan, Ting Yang, Dan Xu, Mei Chen, Lei Chen

“…However, based on two studies with 324 patients, benefit of antifibrotic drugs in FVC was not shown in the subgroup taking mycophenolate (mean difference 17.08; 95% CI -56.22 to 90.37), which also had higher risk of SAEs (RR 1.71; 95% CI 1.09 to 2.70), although both were contested by TSA.<h4>Conclusion</h4>Our study suggests that antifibrotic drugs are beneficial for patients with non-IPF ILDs in slowing disease progression, whereas may not correlate to all-cause mortality and SAEs. …”
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Conventional type 1 dendritic cells in the lymph nodes aggravate neuroinflammation after spinal cord injury by promoting CD8+ T cell expansion by Li-Qing Wang, Xiao-Yi Wang, Yue-Hui Ma, Heng-Jun Zhou

“…The Basso Mouse Scale score of SCI mice was increased and the proportion of CD8+ T cells in blood and spinal cord tissue was decreased after FTY-720 injection. Both migratory cDC1s (CD103+) and resident cDC1s (CD8α+) were present in the LNs surrounding the injured spinal cord of SCI mice. …”
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Effects of lower limb strengthening training on lower limb biomechanical characteristics and knee pain in patients with patellofemoral pain: a systematic review and meta-analysis by Zeyang Zhang, Zeyi Zhang, Bosong Zheng, Yuhang Yang, Youping Sun

“…The results show that both types of strengthening training positively impact pain reduction and improved knee function in PFP patients. …”
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Heterogeneity analysis provides evidence for a genetically homogeneous subtype of bipolar-disorder. by Caroline C McGrouther, Aaditya V Rangan, Arianna Di Florio, Jeremy A Elman, Nicholas J Schork, John Kelsoe, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium

“…<h4>Background</h4>Bipolar Disorder (BD) is a complex disease. It is heterogeneous, both at the phenotypic and genetic level, although the extent and impact of this heterogeneity is not fully understood. …”
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Linear dimensional changes and surface hardness of acetal resin in different periods of artificial saliva immersion in comparison with heat cure acrylic. by Sura S. Khalid, Widad A. AL-Nakkash

“…The immersion in saliva for three periods- 24hrs, 15 days, 30 days has no significant diffeence on linear dimensional change on both acrylic and acetal denture bases. Acetal group exhibited higher surface hardness than acrylic group. …”
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SPA14 liposomes combining saponin with fully synthetic TLR4 agonist provide adjuvanticity to hCMV vaccine candidate by Ernesto Luna, Sophie Ruiz, Marie Garinot, Cyril Chavagnac, Pankaj Agrawal, John Escobar, Laurent Revet, Marie-Jeanne Asensio, Fabienne Piras, Francis G. Fang, Donald R. Drake, Bachra Rokbi, Daniel Larocque, Jean Haensler

“…When tested as an adjuvant in vivo with human cytomegalovirus glycoprotein B (gB) and pentamer complex (PC) as test antigens, SPA14 was generally well tolerated and as active as AS01B for the induction of long-lasting CMV-neutralizing antibodies in mice and non-human primates (NHPs). Both adjuvants promoted the induction of Th-1 responses based on IgG2c production in mice and IFN-γ production in mice and NHPs, but in mice, a higher level of Th-2 cytokines (IL-5) and higher IgG1 over IgG2c secreting cells ratios were obtained with SPA14 indicating that the adjuvant profile of SPA14 could be less Th-1 biased than that of AS01B. …”
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Economic Impact of Postoperative Urinary Retention in the US Hospital Setting by Weijia Wang, Arielle Marks-Anglin, Vladimir Turzhitsky, Robert J. Mark, Aurelio Otero Rosales, Nathaniel W. Bailey, Yiling Jiang, Joseph Abueg, Ira S. Hofer, Toby N. Weingarten

“…Unadjusted results showed that POUR was associated with greater charges in both inpatient ($92&#8239;529 with POUR vs $78&#8239;556 without POUR, _p_ < .001) and outpatient ($48&#8239;996 with POUR vs $35&#8239;433 without POUR, _p_ < .001) settings. …”
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Factors Affecting Male Involvement in Family Planning at Kazo Health Center IV in Kazo Town Council Kazo District. by Ndyaguma, Laban

“…A cross sectional research design was used for this study where both quantitative and qualitative methods were employed, the population of the study included Women, Men, health staff and local leaders. …”
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Advertisement and Sales Performance in Mtn Uganda, Kabale Branch. by Mwebesa, Acleo

“…The respondents comprised employees of MTN Uganda, Kabale district, Qualitative data was analyzed using both descriptive and inferential statistics. Descriptive statistics included the use of frequencies and percentages to analyze biodata, while inferential statistics included the use of mean and standard deviations to test individual responses; as well as the Pearson correlation coefficient (r) to test the relationship between advertisement and sales performance of the MTN Uganda Kabale branch. …”
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Compensation and Retention of Civil Servants in Uganda: A Case of Rubanda District Local Government. by Tubenawe, Akileo

“…This study used a cross-sectional survey research design utilizing both qualitative and quantitative data approaches. …”
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Assessment of the Effect of Flooding on Agricultural Lands in Kaharo Sub-County of Kabale District South Western Uganda. by Nyakiti, Dorcas Awino

“…The study employed descriptive survey design utilizing both qualitative and quantitative data collection and analyses methods. …”
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Cash Management Practices and Performance of Businesses in Uganda: A Case Study of Northern Division Kasese District. by Mirembe, Philip

“…A descriptive design was used in the study. The researcher used both Primary and secondary data. Secondary data was collected from the business's financial statements and policies. …”
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Political Interference and Social Service Delivery in Kanaba Sub-County Kisoro District. by Tumushime, Bosco

“…The study employed a cross-sectional descriptive design and employed both qualitative and quantitative. The study involved 75 people who acted as respondents. …”
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