Impact of Oxycodone HCl Extended-release Formulary Restrictions on Extended-release Opioid Market Share, Healthcare Resource Utilization and Costs in Commercial and Medicare Plans by Rolin L. Wade, Chi-Chang Chen, Ajita P. De, Jaren C. Howard

“…ER opioid market share and healthcare resource utilization/costs for both cases and controls were evaluated for the 6-month period before and after the formulary restriction dates. …”
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The Validity of a Portable Strain-Gauge Apparatus Versus a Commercial Isokinetic Dynamometer for Evaluating Knee Extension Kinetics by Dustin Oranchuk, Chris Juneau, Shelley Diewald, Jono Neville, John Cronin

“…Peak force (PF), peak rate of force development (PRFD), rate of force development (RFD~2080~) and impulse (IMP~2080~) from 20-80% of onset to peak force were assessed using both strain-gauge and isokinetic dynamometer. Between-device differences were evaluated by the Wilcoxon signed-rank test, Cohen's *d* effect sizes (ES), Pearson's correlation coefficients (*r*), and Bland-Altman plots…”
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A COMPARATIVE STUDY ON THE EFFECT OF SISAL FIBRE AND WASTE PLASTIC STRIPS IN STRUCTURAL STRENGTH IMPROVEMENT OF TROPICAL BLACK CLAY by YOHANNA PAUL, BADAMASI ABDULRAHMAN, ISHOLA KAZEEM, ODOH KELVIN CHUKWUEBUKA, ABDULKADIR MOHAMMED NYAKO, FWANGSHAK GAYUS MIJE

“…In the case soil treated with waste plastic strips, liquid values increased from 43.4% for the natural soil to a highest value of 58% at 1% waste plastic strips and thereafter decreased to 49.15% at 2% waste plastic strips content. Plastic limit for both BCS-sisal fibre/ waste plastic strips initially decreased from its natural value of 25.78 to 15.55 and 14.77% when treated with sisal fibre and waste plastic strips respectively at 0.5% admixtures content. …”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…., BA.5.2) were associated with more severe outcomes, while XBB and BA.2.86 showed lower pathogenicity, with a marked reduction in severe and fatal cases (P < 0.05).ConclusionAs SARS-CoV-2 variants evolve, the incidence of severe cases has progressively decreased. Both XBB and BA.2.86 variants exhibit lower pathogenicity. …”
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Application of the DEB-TKTD model with multi-omics data: Prediction of life history traits of Chinese mitten crab (Eriocheir sinensis) under different salinities by Hanzun Zhang, Shipeng Dong, Hongwei Shan, Chao Yang, Fang Wang

“…Subsequently, tissues including the eyestalk, posterior gill, hepatopancreas, and ovary were sampled from crabs in both the freshwater control group and the 18 ‰ salinity treatment group for transcriptional and metabolomic analysis. …”
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Community-based HPV self-collection versus visual inspection with acetic acid in Uganda: a cost-effectiveness analysis of the ASPIRE trial by Joel Singer, Angeli Rawat, Heather Armstrong, Josaphat Byamugisha, Gina S Ogilvie, Alex K Mezei, Heather N Pedersen, Stephen Sy, Catherine Regan, Sheona M Mitchell-Foster, Musa Sekikubo, Jane J Kim, Nicole G Campos

“…The trial compared screening uptake and compliance with follow-up in two arms: (1) community-based (ie, home or workplace) self-collected HPV testing (facilitated by community health workers) with clinic-based visual inspection with acetic acid (VIA) triage of HPV-positive women (‘HPV-VIA’) and (2) clinic-based VIA (‘VIA’). In both arms, VIA was performed at the local health unit by midwives with VIA-positive women receiving immediate treatment with cryotherapy.Design We informed a Monte Carlo simulation model of HPV infection and cervical cancer with screening uptake, compliance and retrospective cost data from the ASPIRE trial; additional cost, test performance and treatment effectiveness data were drawn from observational studies. …”
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Emergency and critical care medicine residents’ competency to identify patient ventilator asynchrony using a mechanical ventilator waveform analysis in Addis Ababa, Ethiopia: a mul... by Wegderes Bogale, Merahi Kefyalew, Finot Debebe

“…Only 1 resident (1.25%) identified all 6 different types of PVAs,;(8.75%) identified 5 PVAs; 20% identified 4 PVAs,22.5% identified 3 PVAs; 17.5% identified 2 PVAs, 13.75% identified 1 PVA Correctly and 16.25% did not identify any PVA. Auto-PEEP was the most frequently identified PVA, and delayed cycling was the least frequently identified PVA. …”
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Immunologic and inflammatory consequences of SARS-CoV-2 infection and its implications in renal disease by Hiam Naiditch, Michael R. Betts, H. Benjamin Larman, Moshe Levi, Avi Z. Rosenberg

“…It became increasingly recognized that the immune response was a key mediator of illness severity and that its mechanisms needed to be better understood. Early infection of both tissue and immune cells, such as macrophages, leading to pyroptosis-mediated inflammasome production in an organ system critical for systemic oxygenation likely plays a central role in the morbidity wrought by SARS-CoV-2. …”
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The first experience of two-stage treatment of transsphincteric fistulas of rectum by means of fibrin sealant by S. A. Frolov, A. M. Kuzminov, V. Yu. Korolik, I. S. Bogormistrov, M. O. Chernozhukova, Sh. T. Minbayev

“…Strict patient selection with transsphincteric rectal fistulas and careful preoperative investigation allow to improve treatment results due to technical simplicity of the method as well as due to low complication rate both in early, and in remote periods.…”
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Causal machine learning models for predicting low birth weight in midwife-led continuity care intervention in North Shoa Zone, Ethiopia by Wudneh Ketema Moges, Awoke Seyoum Tegegne, Aweke A. Mitku, Esubalew Tesfahun, Solomon Hailemeskel

“…Additionally, the estimated ITE for both the T-learner and X-learner was less than -0.5, indicating that mothers would not choose to participate in the MLCC program. …”
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Acceptability and feasibility of pre-exposure prophylaxis for bacterial STIs: a systematic review. by Julie-Anne Carroll, Amy B Mullens, Sarah Warzywoda, Philip R A Baker, Meika Stafford, Faye McMillan, Jacintha Manton, Daniel Demant

“…This process supports the improvement of health outcomes, strengthens healthcare systems, and ensures that healthcare interventions, such as STI PrEP, are effectively understood and implemented by both healthcare providers and at-risk populations. …”
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Qualitative application of the diffusion of innovation theory to maternity waiting homes in rural Zambia by Jeanette L. Kaiser, Rachel M. Fiorillo, Taryn Vian, Thandiwe Ngoma, Kayla J. Kuhfeldt, Michelle L. Munro-Kramer, Davidson H. Hamer, Misheck Bwalya, Viviane R. Sakanga, Jody R. Lori, Eden Ahmed Mdluli, Peter C. Rockers, Godfrey Biemba, Nancy A. Scott

“…Results Utilization of MWHs was higher among intervention (65.4%) than control women (42.5%). Respondents in both study arms perceived relative advantages to pregnant women staying at MWHs compared to going directly to health facilities when labor begins. …”
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Isokinetic Assessment of Knee Flexor and Extensor Strength and Lower Extremity Flexibility Assessment of an NCAA Division III Men’s Soccer Team by Savanna Perkins, Paul Canavan

“…The benefits of this research have direct implications, as participants received both their screening data and a set of exercises aimed to help decrease their injury risk, in addition to the offering data that is useful for determining what normative values for flexibility and strength profiles might look like for Division III male soccer players…”
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The position of Lithuanian parties towards Poland in 1920-1926: from modus vivendi to permanent confrontation by Andrius Grodis

“…Having approved the project, there were hopes not only to regain the capital, to start economic relations useful for both countries, but also to receive support from great Western states, which was vital for Lithuania as for other Baltic states in seeking protection from the eventual threat of Soviet Russia and Germany. …”
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Comparative analysis of ocular biometrics using spectral domain optical coherence tomography with Purkinje image and optic nerve head alignments in mice by Ying Hon Sze, Bing Zuo, Da Qian Lu, King Kit Li, Dennis Yan Yin Tse, Qian Zhao, Thomas Chuen Lam

“…When considering temporal changes from P21 to P35, both methods showed similar results, with significant elongation of ACD, LT, and AL as expected. …”
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Long-term efficacy and safety of alemtuzumab in participants with highly active MS: TOPAZ clinical trial and interim analysis of TREAT-MS real-world study by Tjalf Ziemssen, Ann D. Bass, Bart Van Wijmeersch, Sara Eichau, Stephan Richter, Frank Hoffmann, Nicole M. Armstrong, Magdalena Chirieac, Janete Cunha-Santos, Barry A. Singer

“…Stable/improved EDSS scores were achieved by 74% of HAD participants in CARE-MS I, 67% in CARE-MS II (both Year 11), and 79% in TREAT-MS (Year 3.6), with 6-month CDI achieved by about half at Year 11 (CARE-MS I, II). …”
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Ecosystem carbon stock variation along forest stand ages: insight from eastern coast mangrove ecosystem of India by Muktipada Panda, Bikash R. Dash, Sudam C. Sahu

“…Among mangrove species, Avicennia marina contributed the highest vegetation biomass in both forest stands (59.72 t ha−1 and 262.28 t ha−1 in young and old stands, respectively), followed by Avicennia officinalis (35.05 t ha−1) and Sonneratia apetala (26.09 t ha−1) in young stand and Avicennia alba (169.28 t ha−1) and Avicennia officinalis (115.58 t ha−1) in old stand. …”
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Healthcare Costs and Resource Use Associated With Cervical Intraepithelial Neoplasia and Cervical Conization: A Retrospective Study of German Statutory Health Insurance Claims Data by Anna-Janina Stephan, Miriam Reuschenbach, Kunal Saxena, Vimalanand S. Prabhu, Christian Jacob, Kim M. Schneider, Wolfgang Greiner, Regine Wölle, Monika Hampl

“…Frequency of outpatient physician visits was significantly higher in both study cohorts (43.23 visits, P<.01 and 38.60 visits, _P_<.01) compared with the control group (32.07 visits). …”
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Spinally targeted paired associative stimulation with high-frequency peripheral component induces spinal level plasticity in healthy subjects by Anna Nätkynmäki, Leena Lauronen, Piia Haakana, Erika Kirveskari, Janne Avela, Anastasia Shulga

“…MEPs were significantly enhanced in both interventions. In the SPINAL but not in the CORTICAL session, maximal H-reflex amplitudes significantly increased at two timepoints, indicating an increase in spinal excitability. …”
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A broad assessment of forty-one skin phenotypes reveals complex dimensions of skin ageing by Jun Yan Ng, Qi Yi Ambrose Wong, Jun Jie Lim, Dingyu Cen, Jia Yi Karen Wong, Yi Ying Eliza Lim, Yang Yie Sio, Kavita Reginald, Yee-How Say, Fook Tim Chew

“…In this broad assessment of skin ageing, we first described the prevalence of forty-one signs of skin ageing and then characterised in detail both the prevalence and severity distribution of ten key skin ageing phenotypes. …”
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