Modeling Portfolio Optimization based on behavioral Preferences and Investor’s Memory by vahideh mousavi kakhki, Sanaz Khatabi

“…We employ a Genetic Algorithm (GA) to optimize portfolios under both criteria. GA is a robust optimization technique that can effectively handle complex problems with multiple constraints. …”
Get full text

Surgeons are apprehensive to use DCD lungs despite similar post-transplant outcomes: A 20-year UNOS retrospective analysis by J. Sam Meyer, MSc, Oliver K. Jawitz, MD, MHS, Yury Peysakhovich, MD, Dan Aravot, MD, Matthew G. Hartwig, MD, MHS, Yaron D. Barac, MD, PhD

“…A history of diabetes for over 10 years was strongly associated with non-use for DCD lungs (OR, 0.87, P = 0.71), whereas an under 10-year history was associated with increased use (OR 2.33, P = 0.008, OR 1.07 P = 0.819).Lungs from donors ages 40–49 are more likely to be procured than those <30 or >50 in both DBD and DCD. However, likelihood of procurement is 1.84 [95% 1.42, 2.38, p < 0.001] times higher in 40–49-year-old vs. <30-year-old donors when comparing DBD vs. …”
Get full text

Dynamics of Somatic and Comorbid Mental Disorders (Distress, Anxiety, Somatisation and Depression) in Patients with Irritable Bowel Syndrome during Therapy with Alimemazine: Result... by V. T. Ivashkin, O. Z. Okhlobystina, M. V. Mayevskaya, O. S. Shifrin, Z. A. Mamieva, Yu. E. Azimova

“…The Four-Dimensional Symptom Questionnaire (4DSQ) was used to assess the dynamics and effectiveness of the treatment in terms of the patients’ mental state, while the “7 symptoms per 7 days” (“7 × 7”) questionnaire was used to assess the dynamics of IBS symptoms and concomitant functional dyspepsia (FD). Both questionnaires were offered to the patients three times: before the start of the treatment and following 2 and 4 weeks of the therapy.Results. …”
Get full text

Potential public health impacts of gonorrhea vaccination programmes under declining incidences: A modeling study. by Lin Geng, Lilith K Whittles, Borame L Dickens, Martin T W Chio, Yihao Chen, Rayner Kay Jin Tan, Azra Ghani, Jue Tao Lim

“…Sensitivity analyses indicated that VaR had the greatest public health impact with the highest number of averted cases per dose for vaccines of any efficacy or duration of protection (or both), although VoD and VoD(H) saved more vaccine resource and had the highest number averted MSM cases per dose for highly protective vaccines of long protection.…”
Get full text

Fatty Acids of Erythrocyte Membranes and Blood Serum as Possible Predictors of Exacerbation in Patients with Inflammatory Bowel Diseases by M. V. Kruchinina, M. F. Osipenko, A. I. Valuyskikh, E. Yu. Valuiskikh, I. O. Svetlova

“…In the acute stage, patients with IBD have a higher total content of saturated fatty acids (SFAs) in erythrocyte membranes compared to the control group (p = 0.006), and, on the contrary, lower levels of unsaturated fatty acids (UFAs) (p = 0.005), mainly due to polyunsaturated FAs (PUFAs) (p = 0.026), namely omega-6 PUFAs (p = 0.011).Remission of IBD is associated with an increase in the level of a number of SFAs in the blood serum — margaric C17:0 (p = 0.024), arachidic acid (C20:0) — in erythrocyte membranes and serum (p = 0.0001 and p = 0.019, respectively), with a decrease in the total content of monounsaturated FAs in erythrocyte membranes (p = 0.022), an increase in the total concentration of PUFAs due to both omega-3 PUFAs (p = 0.0008) and omega-6 PUFAs (p = 0.033) in erythrocyte membranes compared with a group of healthy individuals.The exacerbation stage in patients with IBD examined over time is associated with higher levels of stearic FA C18:0 (p = 0.005), SFA/UFA (p = 0.034) and SFA/PUFA (p = 0.039) ratios in erythrocyte membranes, serum level of arachidic FA C20:0 (p = 0.008), and, on the contrary, lower content of UFAs in erythrocyte membranes — eicosapentaenoic C20:5n-3 (p = 0.0023), eicosadienoic C20:2n-6 (p = 0.0027), hexadecadienoic C16:2n-6 (p = 0.006), docosatetraenoic C22:4n-6 (p = 0.008) and alpha-linolenic C18:3n-3 (p = 0.039).A combined “panel” of fatty acids, including the levels of C20:2n-6, C18:0 in erythrocyte membranes and the content of C20:0 in blood serum, provided an AUC of 0.683 (95 % CI: 0.500–0.844), sensitivity 91.4 %, specificity 68.3 %.Levels of C20:5n-3, C20:2n-6, C18:0, C16:2n-6, C22:4n-6, C18:3n-3 fatty acids, SFA/UFA and SFA/PUFA ratios in erythrocyte membranes and content C20:0 in blood serum, used as biomarkers — predictors of the development of exacerbation in patients with IBD who were in remission, predicted the development of exacerbation of IBD after 2–4 months in the case of maximally changed levels of FAs, after 6–8 months — with moderately changed levels FAs, maintaining remission for 12 months — with minimally changed FAs levels.Conclusion. …”
Get full text

Acid-Unlocked Two-Layer Ca-Loaded Nanoplatform to Interfere With Mitochondria for Synergistic Tumor Therapy by Zheng Y, Williams GR, Hu R, Tong S, Xu J, Wang T, Zhang Y, Wu J, Li F, Cai Y, Zhu LM

“….- Potent anti-tumor effects are seen both in vitro and in vivo.Keywords: Calcium ion load, controlled-release nanomaterials, two-layer protective shell, pH responsive drug release, reactive oxygen species, anti-cancer…”
Get full text

The diagnostic value of the combined application of blood lipid metabolism markers and interleukin-6 in osteoporosis and osteopenia by Liping Fan, Jiahao Chen, Chong Chen, Yongwei Zhang, Yeqing Yang, Zhe Chen

“…Finally, the diagnostic efficiency of lipid metabolism markers and IL-6 for osteoporosis and osteopenia was assessed using receiver operating characteristic (ROC) curves. Results (1) In both males and females, a negative relationship was observed between BMD and several biomarkers, including total cholesterol (TC), apolipoprotein B (ApoB), low-density lipoprotein cholesterol (LDL-C), free fatty acids (FFAs), and IL-6. …”
Get full text

Presenting a Framework of Effective Factors on the Implementation of Policies in the Field of Protection and Exploitation of Forests in the North of the Country by Davoud Hosseinpoor, Seyed Mahdi Alvani, Hossein Aslipour, Aghil Ghorbani Paji

“…It was found that the roles of street-level bureaucrats, the active participation of citizens, the design and implementation of toolkits, eco-oriented development strategies, and effective problem-solving mechanisms are the main components that must be prioritized in both policy-making and implementation processes to achieve successful outcomes. …”
Get full text

Pengembangan Aplikasi Sistem Informasi Pendataan Bangunan (SIPBANG) pada Dinas Pekerjaan Umum dan Penataan Ruang (DPUPR) Kota Malang Menggunakan Framework Scrum by Muhamad Rifky, Yusi Tyroni Mursityo, Bondan Sapta Prakoso

“…Besides, management project was used as the method that would ease the arrangement of general project planning from initialization, planning, implementation, evaluation, and closing. Both of them will be combined with Scrum used in one of the project management stages, which is implementation that consist of building the system. …”
Get full text

Kontrol Level Kecepatan Kipas Melalui Deteksi Gestur Jari Tangan Menggunakan MediaPipe dan Faster-RCNN by Muhammad Aldi Fakhruddin, Heri Pratikno, Musayyanah, Weny Indah Kusumawati

“…MediaPipe serves to detect the shape of the finger feature gestures of both hands and Faster-RCNN is used to process the classification of four finger gestures to turn off the fan or turn on the fan with its rotational speed at level 1, level 2 or level 3. …”
Get full text

Optimization of Identification and Zoning Method for Landscape Characters of Urban Historic Districts by Hong YUN, Zixuan HU, Zehao HU

“…Based on this, this research optimizes the landscape gene theory for the buildings of urban historic districts by: 1) Strengthening the historic layering analysis of architectural gene; 2) adjusting the identification principles of architectural genes by not only adding a new principle of geographical representation, but also justifying the weight between principles; 3) implementing the binary identification of both architectural genes and recessive genes; 4) establishing a general classification system for architectural genes and recessive genes, with the new classification system involving three levels, of which the architectural genes and the recessive genes are respectively divided into six and seven subitems; 5) strengthening the correlation analysis of the binary genes. …”
Get full text

Changes of Narrative: Osvald Sirén’s Photographic Modeling of Modern Research on Chinese Garden by Jiuwen GU, Yuanfeng SHI, Shan JIA

“…ObjectivePhotography, as an innovative method of recording Chinese gardens in the late nineteenth and early twentieth centuries, has a significant impact on the research on gardens both then and in later generations. In spite of this, garden research and photographic research do not overlap much as they are two parallel disciplines. …”
Get full text

Evaluation of Dynamic Visual Perception of Riverside Interface in Mountainous Cities from the Perspective of Boating by Dan LUO, Ruhong WEI

“…The research forms a technical path for both perception evaluation and spatial optimization, which may provide a theoretical support and practical guidance for the construction of livable mountain cities.…”
Get full text

Zolpidem: Efficacy and Side Effects for Insomnia by Amber N. Edinoff, Natalie Wu, Yahya T. Ghaffar, Rosemary Prejean, Rachel Gremillion, Mark Cogburn, Azem A. Chami, Adam M. Kaye, Alan D. Kaye

“…Decisions for whether or not to prescribe it and the dosage should be made on a case-by-case basis, considering both the psychical and psychiatric risks posed to the patient with insomnia versus if the patient were to take zolpidem to treat their condition.…”
Get full text

Evaluation on Carbon Sequestration Capacity of 30 Common Landscaping Tree Species in Beijing by Jing QIAN, Sidong SHEN, Shuxin FAN, Li DONG

“…Among all the tested tree species, the annual carbon sequestration per plant of arbors is significantly higher than that of shrubs, but there is no significant difference between the two in terms of both the annual carbon sequestration per unit land area and the annual carbon sequestration per unit leaf area. …”
Get full text

Characteristics of Traditional Human Settlement Landscapes on Bedrock Islands in Guangdong Based on the “Ao” Unit by Ying PAN, Linxi CHEN, Ying SHI

“…The dominant industries, such as fishing and trade, are closely tied to both the Ao units and their coastal locations, making them focal points for village and town settlements. …”
Get full text

Evaluation of Urban Composite Carbon Sink Value: A Case Study of Shenyang by Tiemao SHI, Di WANG, Yu TANG, Peiying LI

“…This is because human activities such as urban construction, transportation, and industrial production can have both positive and negative impacts on carbon sink. …”
Get full text

Analysis of the Rights and Obligations of Stakeholders in China’s National Park Concession System by Le ZHONG, Zhicong ZHAO

“…The research addresses the gaps in existing research, thereby serving as a valuable reference for both theoretical inquiry and practical development of China’s national park concession system, with a focus on balancing stakeholders’ rights and obligations. …”
Get full text

Deteksi Covid-19 pada Citra Sinar-X Dada Menggunakan Deep Learning yang Efisien by Novanto Yudistira, Agus Wahyu Widodo, Bayu Rahayudi

“…CNN with fewer parameters can save storage and memory usage so that it can process in real time both in the form of detection devices and decision-making systems via the cloud. …”
Get full text

Editorial by Jörg Tremmel, Marisa dos Reis, Joseph Burke, Raphaelle Schwarzberg (†)

“…This poses particular difficulties at both a legal and an institutional level. If law is understood as person-affecting, that is: specifying rights of particular people, it inevitably neglects the interests of the unborn. …”
Get full text