Security of Physical Library Materials and Utilisation: A Case Study of National Teachers College Kabale. by Arineitwe, Doreen

“…., fire or flood) and damage from careless handling or poor environmental conditions. …”
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FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms by Manish Kumar, Abhishek Singh Sengar, Anushree Lye, Pranesh Kumar, Sukhes Mukherjee, Dinesh Kumar, Priyadip Das, Suvro Chatterjee, Adele Stewart, Biswanath Maity

“…Though the etiology of doxorubicin-dependent heart damage has yet to be fully elucidated, the ability of doxorubicin to damage DNA and trigger oxidative stress have been heavily implicated in the pathogenesis of chemotherapy-associated cardiomyopathy. …”
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Early tolerance and late persistence as alternative drug responses in cancer by Simona Punzi, Davide Cittaro, Guido Gatti, Gemma Crupi, Oronza A. Botrugno, Antonino Alex Cartalemi, Alon Gutfreund, Caterina Oneto, Valentina Giansanti, Chiara Battistini, Giovanni Santacatterina, Lucrezia Patruno, Ilaria Villanti, Martina Palumbo, Daniel J. Laverty, Francesca Giannese, Alex Graudenzi, Giulio Caravagna, Marco Antoniotti, Zachary Nagel, Ugo Cavallaro, Luisa Lanfrancone, Timothy A. Yap, Giulio Draetta, Nathalie Balaban, Giovanni Tonon

“…Here, we show that human cancer cells elicit a tolerant response when exposed to commonly used chemotherapy regimens, propelled by the pervasive activation of autophagy, leading to the comprehensive activation of DNA damage repair pathways. After prolonged drug exposure, such tolerant responses morph into persistence, whereby the increased DNA damage repair is entirely reversed. …”
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Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury by Luying Zhang, Song Yang, Hao Cui, Chenchen Hang, Xingsheng Wang, Le An, Zhenyu Shan, Zhen Liang, Rui Shao, Ziren Tang

“…Abstract Post-cardiac arrest brain injury (PCABI), as the main cause of high mortality and long-term disability in patients, induces mitochondrial damage and cell apoptosis. Hypothermia is well-known as an effective neuroprotective therapy, but its underlying mechanisms deserve further exploration. …”
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Edaravone dexborneol alleviates pericyte-mediated fibrosis depositing extracellular matrix through TGF-β1/IL-11 in cerebral small vessel disease by Qingrui Duan, Zhiyang Liu, Yuxuan Xing, Haifeng Huang, Lin Zhu, Jiaxuan Liu, Peikun He, Guixian Ma, Yuhu Zhang, Kun Nie, Yuyuan Gao, Lijuan Wang

“…Measures of cognitive function, neuronal damage, white matter lesion (WML), the fibrous profiles of pericytes and ECM protein were investigated to assess the effect of EDB. …”
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TOPBP1 as a potential predictive biomarker for enhanced combinatorial efficacy of olaparib and AZD6738 in PDAC by Xiao-Mei Tang, Min-Min Shi, Jia-Cheng Wang, Yi-Jin Gu, Yu-Ting Dai, Qin-Xin Yang, Jia Liu, Ling-Jie Ren, Xin-Yun Liu, Chun Yang, Fang-Fang Ma, Ji-Bing Liu, Hong Yu, Da Fu, Yun-Feng Wang

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and often lethal malignancy, requiring the development of enhanced therapeutic approaches. The DNA damage response (DDR) pathway is frequently altered during PDAC development, leading to an increased occurrence of DNA damage. …”
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Baccaurea ramiflora fruit peel powder supplementation prevented inflammatory cell infiltration, oxidative stress, and fibrosis in carbon tetrachloride (CCl4) administered ovariecto... by Tahsin Zahan, Mirza Alimullah, Ishrat Jahan, Md. Borhan Uddin, Khondker Ayesha Akter, Md. Junaeid Rahman, Shahnaz Siddiqua, Kamrun Nahar Ela, Sakil Amin, Khondoker Shahin Ahmed, Hemayet Hossain, Ferdous Khan, Md Ashraful Alam, Nusrat Subhan

“…This study explored the impact of Baccaurea ramiflora fruit peel powder on oxidative stress and fibrosis in hepatic damage induced by carbon tetrachloride (CCl4) in ovariectomized rats. …”
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Flower thrips, Frankliniella tritici (Fitch) (Insecta: Thysanoptera: Thripidae) by Danielle Sprague, Joseph E. Funderburk, Andrea Lucky

“…Several species in the genus Frankliniella are considered economic pests and cause damage to a wide variety of crops through feeding and oviposition (Childers 1997). …”
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Queensland Fruit Fly, Bactrocera tryoni (Froggatt) (Insecta: Diptera: Tephritidae) by Howard V. Weems, Jr., Thomas R. Fasulo

“…It is not established in the United States, but the extensive damage caused by the larvae of this fly in areas similar to Florida where it has become established indicates that this species could become a serious pest of pome and stone fruit crops, and possibly of citrus, if it were to become established in Florida. …”
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The General Condition of Agriculture in Kalmykia at the beginning of collectivization by Namsyr A. Shikhanov

“…The analysis showed that the agriculture of the Kalmyk Autonomous Region, which suffered significant damage during the Civil War and famine of 1921–1922, managed to recover in almost all directions during the years of the NEP, although it did not reach pre-revolutionary indicators. …”
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Consumers' Response to "Neonic-Free" and Other Insect Pollinator Promotions on Ornamental Plants by Hayk Khachatryan, Alicia Rihn

“…But many nursery and greenhouse growers use neonic-based pesticide control measures because they are effective, inexpensive, and cause less environmental damage than other insecticides. The increased publicity may influence consumer demand and preferences but very few studies have investigated consumer responses to neonic-free labels, and evidence suggests that many consumers have little knowledge or awareness of the issue. …”
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<i>H. pylori</i>-negative peptic ulcer: state-of-the-art by M. A. Osadchuk, A. M. Osadchuk, A. A. Sibrjaev

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Improving CD3 bispecific antibody therapy in solid tumors using combination strategies by Katy Lloyd, Jim Middelburg, Vitalijs Ovcinnikovs, Nora Pencheva, Kristel Kemper, Thorbald van Hall

“…Furthermore, tumor surface antigen selection for an optimal therapeutic window and acceptable collateral damage to normal tissues is challenging. In this review, we discuss recent research investigating combination approaches aimed at improving CD3 bsAb efficacy in solid cancer.…”
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2018–2019 Florida Citrus Production Guide: Weeds by Stephen H. Futch, Brent A. Sellers, Ramdas G. Kanissery

“…The objective of today's weed management program is to suppress and control weeds so that they do not cause damage to the tree, impact yield, or impede grove and harvesting operations. …”
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Controversy About Management of Osteoarthritis with Disease-modifying Anti-rheumatic Drugs by CUI Hanshu, LIU Bin

“…Osteoarthritis (OA) is a degenerative joint cartilage disease characterized pathologically by osteophytes formation and subchondral bone damage. It leads to pain, stiffness, deformation and even disability in the patients, and increases the risk of comorbidities. …”
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2019–2020 Florida Citrus Production Guide: Weeds by Stephen H. Futch, Brent A. Sellers, Ramdas G. Kanissery

“…The objective of today's weed management program is to suppress and control weeds so that they do not cause damage to the tree, impact yield, or impede grove and harvesting operations. …”
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Tawny Crazy Ant (previously known as Caribbean crazy ant) Nylanderia (formerly Paratrechina) fulva (Mayr) (Insecta: Hymenoptera: Formicidae: Formicinae) by Shweta Sharma, John Warner, Rudolf H. Scheffrahn

“…They can infest sidewalks, buildings and gardens, and damage phone lines, air conditioning units and computers. …”
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EFFECT OF ORGANISATIONAL DYNAMICS ON ACCOUNTING PRACTICES OF LISTED DEPOSIT MONEY BANKS (DMBs) IN NIGERIA by Mubaraq Sanni

“…The nature and level of damage arising from accounting scandals and financial irregularities differ based on individual firm characteristics. …”
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SCHOOL-BASED VIOLENCE AND PEACE: IMPROVING LEARNING IN HIGHER EDUCATION AMONG ADULT SURVIVORS OF SCHOOL BULLYING by Jonathan Chukwuemeka Madu, Abugu Solomon Ogbonna

“…Evidence exists of considerable problems with bullying and bullied children in secondary schools that undermine these efforts as a result of their long-lasting effects for the victims, which include hindrance in learning and advantages of higher education in their survivors. The psychological damage and pain caused by bullying can become almost indelible and affect one’s future. …”
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The General Assembly Resolution ˝Protection of the Environment in Relation to Armed Conflicts˝ of 2022: Where We Stand 30 Years after by Vesna Barić Punda, Irena Nišević

“…This work puts emphasis on Principle 13 of the Resolution which, subject to applicable international law, prohibits widespread, long-term and severe damage to the environment. The authors analyse whether such a threshold is too high and restrictive, consequently preventing the Resolution from effectively protecting the environment in accordance with its goals. …”
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