HВcorAg expression in HВeАg-negative hepatitis: correlation to clinical and histological activity and HВsAg-status by O. P. Dudanova, I. A. Pravdolyubova

“…НBcorAg expression did not depend on HВsAg-status, but in HВsAg-negative patients grade of parenchymatous damage, premalignant hepatocyte changes i.e. micro- and macrocellular dysplasia was higher, than in HВsAg-positive patients.…”
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Bauhinia coccinea extract prevents memory loss induced by scopolamine through activation of antiapoptotic and antioxidant pathways in mice by Eunjin Sohn, Bu-Yeo Kim, Yu Jin Kim, Joo-Hwan Kim, Soo-Jin Jeong

“…This study investigated the effects of an ethanol extract from Bauhinia coccinea (EEBC) on memory impairment and neuronal damage in a memory deficit mouse model. EEBC was administered to ICR mice at doses of 50, 100, or 200 mg/kg daily for 3 weeks. …”
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Learning-based locomotion control fusing multimodal perception for a bipedal humanoid robot by Chao Ji, Diyuan Liu, Wei Gao, Shiwu Zhang

“…Excessive collisions can damage the biped robot hardware, and more critically, the absence of multimodal input, such as vision, limits the robot’s ability to perceive environmental context and adjust its gait trajectory promptly. …”
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Case Report: Cholestatic liver disease in the course of erythropoietic protoporphyria associated with renal hypodysplasia and atrial septal defect by Patryk Lipiński, Agnieszka Lipniacka, Maja Klaudel-Dreszler, Lidia Ziółkowska, Grażyna Kostrzewa, Edyta Odnoczko, Robert Wasilewski, Rafał Płoski, Anna Tylki-Szymańska

“…Erytropoietic protoporphyria should be considered in patients with hepatosplenomegaly and cholestasis accompanied by skin damage. The natural history of liver disease in the course of EPP could be determined by other factors, like the co-existence of congenital anomalies.…”
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Metabolic and Genetic Determinants of Lipid Metabolism Disruption in Non-Alcoholic Fatty Liver Disease by O. Yu. Kytikova, T. P. Novgorodtseva, Yu. K. Denisenko, D. A. Kovalevsky

“…Violations in the activity of FADS1 and FADS2 and their genes are accompanied by dysregulation of the metabolic pathway involved in the biosynthesis of fatty acids. This leads to the damage of cell membranes, whose main components are represented by phospholipids. …”
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Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment. by Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila Poisson, Houtan Noushmehr, Douglas Ruden, Ana C deCarvalho

“…Both mutant and wt p53 models exhibited significant activation of the DNA-damage associated interferon (IFN) response in CSCs and differentiated cells, implicating this pathway in the GBM response to therapy. …”
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Innovative nanoparticle-based approaches for modulating neutrophil extracellular traps in diseases: from mechanisms to therapeutics by Haisong Li, Can Li, Cong Fu, Yizhuo Wang, Tingting Liang, Haitao Wu, Chenxi Wu, Chang Wang, Tianmeng Sun, Shuhan Liu

“…While they help capture and eliminate pathogens, NETs’ excessive or dysregulated formation can lead to tissue damage and disease progression. Therapeutic strategies targeting NET modulation have shown potential, but challenges remain, particularly in achieving precise drug delivery and maintaining drug stability. …”
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Properties of Wood Powder Sheets Extruded with Hydroxypropyl Methylcellulose and Citric Acid after Heating by Hiroyuki Hiratsuka, Xiangyu Tao, Yuki Tokunaga, Hiroshi Nonaka

“…Excessive heating at 210 °C was found to damage the sheet. The overall activation energy, calculated from the weight loss during heating, was as low as 46 kJ/mol, indicating that the dehydration and crosslinking of HPMC could occur easily. …”
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Flowering characteristics and breeding system of the rare plant Rosa anemoniflora by YU Qun, RUAN Shuming, SHI Qinghua, HUANG Xiaochun, ZENG Huahao, GAO Wei

“…Releasing effective insects during the flowering period and reducing human damage were important measures for the conservation of R. anemoniflora.…”
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Bioanthropological and Biomechanical Perspectives on Skeletal Senescence Variation by Sayf Muhammad Alaydrus, Muhamad Andri Jauhari

“…Literature Review: Age-related skeletal cellular death and imbalance contributes to bone damage in elders. Senescence also affects skeletal biomechanics, expressed in increased bone porosity and brittleness. …”
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MAIN FACTORS OF INFLUENCE ON GEOECOSYSTEMS OF WATER BASINS AND RISKS OF THEIR DESTRUCTION by V.O. Iemelianov, P.O. Kiriakov, O.M. Rybak, O.O. Paryshev, L.V. Stupina

“…Due to Russia's large-scale armed aggression has added a powerful negative impact on the environment due to the terrible consequences of military actions, primarily related to damage to communications, destruction of enterprises and other hazardous facilities, contamination of water and land resources in conditions of impossibility to exercise effective control and prompt elimination of the negative impact of military operations. …”
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Research Progress of ROS-Mitochondrial Pathway on Cardiovascular Protection of Tea Polyphenols by Tingting DENG, Jinchan PI, Xiaoping PENG, Yufei YAO, Yiquan LI, Wenjuan LI

“…From the perspective of ROS-mitochondrial pathway, the article elucidates how tea polyphenols behaved the beneficial effects against cardiovascular diseases by modulating the expression of mitochondrial fusion and fission proteins, reducing the opening of mitochondrial membrane permeability transition pore, maintaining cellular calcium homeostasis, mitigating mitochondrial DNA damage and regulating mitochondrial apoptosis signaling pathways. …”
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Enhanced image processing and storage for defect evaluation in BIM of inspected steel bridges by Dogan Karluklu, Cecilia Rinaldi, Marianna Crognale, Lucia Figuli, Vincenzo Gattulli

“…The authors table a procedure that can be followed, starting with storing defect images and ending with defect visualization in the BIM environment, and present a discussion on the advantages and limits of the process by examining concepts such as automated data collection by drones, machine vision-based damage identification by color detection technique, BIM and Industry Foundation Classes standardisation applied to inspection data.…”
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Rules for investigation of patients with asymptomatic elevation of serum aminotransferase activity by M. V. Mayevskaya, V. T. Ivashkin, Ye. N. German

“…As a rule, elevation of activity of alanine and-or aspartate aminotransferases (ALT, AST) is considered as highly significant marker of hepatocyte damage. However, it is necessary to remember, that far from all patients with raised level of aminotransferases have serious liver diseases. …”
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Differential affection of the visual information sub-streams in a patient with visual agnosia by Kirstin Lederer, Bruno Fimm, Jorn Munzert, Mathias Reiser, Heiko Maurer, Ferdinand Binkofski, Ferdinand Binkofski, Ferdinand Binkofski, Antonello Pellicano

“…IntroductionVisual agnosia is a deficit of object recognition addressed to the damage of the ventral stream (VS). The dorsal stream (DS) is usually intact in these patients, and it can be derived from well-preserved reaching and grasping of visually presented objects. …”
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Selective laser trabeculoplasty for the treatment of intraocular pressure elevation after viscocanalostomy with Ologen implant in the management of primary open-angle glaucoma: a r... by Ahmed AM Gad, Bahaa-Eldin Hasan Abdulhalim, Amal F Gharib, Amr Mahfouz Mohammed

“…These eyes showed a progression of glaucomatous damage, the IOP was above 21 mmHg, or with intolerable glaucoma medications. …”
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Dynamic evaluation of vertebral alveolar echinococcosis using MR T2 mapping by Jinhuan Han, Yushan Chang, Hui Guo

“…Conclusion The MR T2 mapping technique can quantitatively evaluate the changes of vertebral alveolar echinococcosis, and it shows sensitivity to pathological changes in vertebrae prior to detectable damage using conventional MRI; this offers potential for early detection of vertebral alveolar echinococcosis.…”
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Establishment of an animal model for monkeypox virus infection in dormice by Gaojie Song, Lingling Cheng, Jun Liu, Yu Zhou, Cuiling Zhang, Yuping Zong

“…Virological tests further confirmed the distribution of MPXV in multiple vital organs of dormice, including the lungs, liver, spleen, and trachea, with particularly significant pathological damage observed in lung tissue. An MPXV infection model in dormice was successfully established through intranasal inoculation with a titer of 105.5 PFU MPXV, which can be used for studying the infection mechanism and pharmacology of MPXV.…”
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Neutral zone closing overvoltage characteristics analysis in traction power supply system for group trains by XIANG Nianwen, XU Chenglin, SHAO Bingbing, YUAN Qiankun, YANG Jin, WANG Zhoulong

“…Then, the generated closing overvoltage will cause serious insulation damage to the traction power supply system and the trains′ high-voltage equipment box. …”
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Widespread mutagenesis and chromosomal instability shape somatic genomes in systemic sclerosis by Sriram Vijayraghavan, Thomas Blouin, James McCollum, Latarsha Porcher, François Virard, Jiri Zavadil, Carol Feghali-Bostwick, Natalie Saini

“…We hypothesize that the inflammation and immune response associated with systemic sclerosis can trigger DNA damage, leading to elevated somatic mutagenesis, a hallmark of pre-cancerous tissues. …”
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