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961
Chromium "(VI)" phytoremediation using Azolla pinnata: effects on Vicia faba growth, physiology, cytogenetics, and gene expression profiling
Published 2025-02-01“…It modulates stress-related gene expression, protects DNA integrity, enhances cell mitosis, and reduces chromosomal damage. These results indicate that Azolla has the potential to be a valuable asset in phytoremediation strategies for chromium-contaminated environments, and that it may enhance plant survival and growth under Cr stress conditions. …”
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962
Toxic effects of monocrotophos and glyphosate on the female reproductive organ and aromatase gene expression in climbing perch
Published 2025-01-01“…These agrochemicals caused ovarian damage and alteration in gonadosomatic index and cytochrome P450 aromatase gene expression.…”
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963
Séptimo Congreso Colombiano De Atención Farmacéutica – Encuentro Iberoamericano De Farmacia Hospitalaria Conductual: “Servicios Profesionales Farmacéuticos y Satisfacción de Necesi...
Published 2023-11-01“…En esta séptima versión, la cual se desarrolla en el contexto del trámite legislativo en el Congreso de Colombia de una propuesta de reforma al Sistema de Salud (Proyecto de Ley No. 339 de 2023, Cámara), el programa de nuestro congreso está orientado a evidenciar la contribución de los servicios profesionales farmacéuticos en la satisfacción de las necesidades de pacientes y sistemas de salud. …”
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964
Microglia TRPC1 SUMOylation drives neuroinflammation after stroke by modulating NLRP3 activity via increasing TRPC1 interaction with ARRB2
Published 2025-03-01“…Mice with a loss of TRPC1 SUMOylation in microglia exhibited improved stroke outcomes including reduced behavior deficits, infarct volume, blood brain barrier damage as well as neuronal apoptosis. Mechanistically, SUMOylation of microglial TRPC1 exacerbated neutrophil infiltration into the peri-infarct area. …”
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965
The change rule of smoke dispersion and temperature evolution in fires within lithium iron phosphate energy storage prefabricated cabin
Published 2025-01-01“…This perfluorohexane fire extinguishing system, with a sprinkler intensity of 20 L/(min ·m2), a sprinkler angle of 120°and a particle size of 50 μm, can successfully controls fires and mitigates fire damage. The research results in the article can provide theoretical guidance for the distributed deployment strategy in energy storage prefabricated cabin and fire safety design of monitoring and warning devices.…”
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966
Mitochondria-targeted photothermal-chemodynamic therapy enhances checkpoint blockade immunotherapy on colon cancer
Published 2025-04-01“…This effect has been attributed in several studies to the release of damage-associated molecular patterns (DAMPs) triggered by mitochondrial injury. …”
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967
The unseen perils of oral-care products generated micro/nanoplastics on human health
Published 2025-01-01“…The gut epithelium absorbs some particles, while others are excreted, entering ecosystems, accumulating through the food chain, and causing ecological damage. Although analytical techniques have advanced in detecting MPs/NPs in oral care products, more robust methods are needed to understand their release mechanisms. …”
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968
Mechanism of podophyllotoxin-induced ovarian toxicity via the AMPK/TSC1/mTOR/ULK1 axis in rats on the basis of toxicological evidence chain (TEC) concept
Published 2025-01-01“…Methods: Using the toxicological evidence chain (TEC) as a research method, our team constructed, for the first time, a rat model in which podophyllotoxin caused ovarian damage and investigated the mechanism of the toxic effects of podophyllotoxin on the ovaries. …”
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969
Optimization design of an acoustic cover layer for a cylindrical cavity based on porous materials
Published 2025-03-01“…These disturbances, if not mitigated, can lead to structural fatigue or damage to sensitive equipment. To address this problem, porous materials, renowned for their lightweight and sound-absorbing properties, have been widely investigated and applied to noise reduction and vibration damping for payload fairings. …”
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970
Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa)
Published 2025-01-01“…However, the exact ways DON causes intestinal damage in pigs still need to be fully understood. …”
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971
The effect of blue-blocking intraocular lenses on circadian biological rhythm: protocol for a randomised controlled trial (CLOCK-IOL colour study)
Published 2015-05-01“…Meanwhile, blue light causes photochemical damage to the retina, and may be associated with age-related macular degeneration (AMD). …”
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972
Physiological and multi-omics analysis revealed the mechanism of arbuscular mycorrhizal fungi to cadmium toxicity in green onion
Published 2025-01-01“…The ameliorative effect of AMF on Cd toxicity was mainly due to a reduction in malondialdehyde content in leaves (30.12 %) and an enhancement of antioxidant enzyme activities (peroxidase, catalase, superoxide dismutase, glutathione reductase and reduced glutathione) that mitigated damage from excessive reactive oxygen species. In addition, AMF induced secretion of easily extractable glomalin soil protein and total glomalin-related soil protein and inhibited the translocation of Cd to the shoots. …”
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973
Oxidative potential determines the oxidative stress and ferroptotic toxicity of airborne particulate matter on pulmonary epithelial cells
Published 2025-02-01“…Furthermore, the reduction of OP reversed redox imbalance and alleviated lung damage in vivo. This study provides additional insights into the structure-activity relationship for PM’s toxicity. …”
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974
Toward Understanding of Quiet Human Resource Management Theory in Iranian Organizations: Theoretical Origins, Conceptual Narration and its Consequences
Published 2024-11-01“…The consequences of quiet HRM are both positive, such as skill diversification and identification of high performers, and negative, including increased turnover, damage to employer branding, and declines in employee mental health, job satisfaction, and performance. …”
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975
Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease
Published 2025-02-01“…FuRong Laboratory, Changsha, Hunan, 410078, People’s Republic of China, Email [email protected] Jian Wang, The Institute of Reproduction and Stem Cell Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410006, People’s Republic of China, Email [email protected]: Ferroptosis is a form of programmed cell death triggered by iron-dependent lipid peroxidation, characterized by iron accumulation and elevated reactive oxygen species (ROS), leading to cell membrane damage. It is associated with a variety of diseases. …”
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976
Dynamic 19F-MRI of pulmonary ventilation in lung transplant recipients with and without chronic lung allograft dysfunction
Published 2025-02-01“…Background: By the time chronic lung allograft dysfunction (CLAD), with its main phenotypes bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), is diagnosed by pulmonary function testing, irreversible damage to the lung allograft may already have occurred. …”
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977
MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism
Published 2025-02-01“…HUVEC activity and mitochondrial structure and function were detected to explore the ability of MT2A to alleviate CPO-induced damage. Finally, a rat model of 2-vessel occlusion plus encephalo-myo-synangiosis (2VO + EMS) with CPO was established to test the proangiogenic effect of MT2A through the copper–mitochondria regulatory mechanism in chronically ischemic brains. …”
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978
Cellular rejuvenation protects neurons from inflammation-mediated cell death
Published 2025-02-01“…This is supported by immunostaining demonstrating alterations to the nuclear envelope, modifications in chromatin marks, and accumulation of DNA damage. Transduction of RGCs with an Oct4-Sox2-Klf4 adeno-associated virus (AAV) to rejuvenate the transcriptome enhances RGC survival in EAE and improves visual acuity. …”
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979
β2 integrin regulates neutrophil trans endothelial migration following traumatic brain injury
Published 2025-02-01“…Abstract Neutrophils are the first responders among peripheral immune cells to infiltrate the central nervous system following a traumatic brain injury (TBI), triggering neuroinflammation that can exacerbate secondary tissue damage. The precise molecular controls that dictate the inflammatory behavior of neutrophils post-TBI, however, remain largely elusive. …”
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980
Advancements in noninvasive techniques for transplant rejection: from biomarker detection to molecular imaging
Published 2025-02-01“…Traditional biomarkers, such as creatinine and troponin, offer limited predictive value owing to their low specificity, and conventional imaging techniques often fail to detect early organ damage, increasing the risk of undiagnosed rejection episodes. …”
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